1.
Br J Cancer
; 89(5): 860-3, 2003 Sep 01.
Article
in English
| MEDLINE
| ID: mdl-12942118
ABSTRACT
Tropomyosin 1 (TM1) is downregulated in a number of transformed cell types, and exogenous expression of TM1 can restore actin organisation and reverse cellular transformation. We find that TM1 is also downregulated in human neuroblastoma cell lines, correlating with increasing malignancy. However, exogenous TM1 does not restore actin cytoskeleton organisation in neuroblastoma cells.