Avaliação de lesões cariosas e biofilme dentário por fluorescência em pacientes portadores da síndrome metabólica submetidos à cirurgia bariátrica: um estudo de coorte prospectivo / Evaluation of caries lesions and dental biofilm by fluorescence, in patients with metabolic syndrome submitted to bariatric surgery: a prospective cohort study

A obesidade e a síndrome metabólica têm aumentado em proporções preocupantes em nível mundial. Além das consequências sistêmicas, a obesidade e suas comorbidades também têm sido relacionadas com a condição bucal. O objetivo deste estudo foi identificar a progressão de lesões cariosas, presença de biofilme dentário, fluxo salivar e presença de saburra lingual em indivíduos eutróficos, sendo avaliados em dois momentos e portadores de síndrome metabólica antes e após a cirurgia bariátrica. A amostra foi constituída por 150 indivíduos, divididos em dois grupos: grupo controle (GC: 75) e grupo obeso (GO: 75), ambos avaliados em T0 e T1, sendo GC 6 meses após a primeira avaliação e GO 6 meses após a cirurgia bariátrica. A avaliação antropométrica dos indivíduos foi realizada por meio do IMC e circunferência da cintura. Os índices ICDAS II e CPOD foram utilizados para avaliar a progressão da cárie dentária. O método de fluorescência verde (QLF- Quantitative Light-induced Fluorescence) avaliou a perda mineral nas superfícies lisas dos dentes e presença de biofilme dentário. O fluxo salivar estimulado foi avaliado em mL/min. O Índice de Saburra Lingual foi utilizado para a avaliação da presença de saburra na língua. Para análise estatística, utilizou-se os testes Qui Quadrado, Exato de Fisher, Mann-Whitney, Kruskal-Wallis e Regressão Logística Múltipla, adotando nível de significância de 5%. Os resultados mostraram que houve diferença significativas entre os grupos, GC apresentou maior número de dentes hígidos (p=0,038) e dentes sem alteração no esmalte (p=0,005) quando comparado ao GO. Ao comparar GC e GO no T1, verificou-se que houve diferença significativa em relação ao CPOD (p<0,0001), dentes restaurados (p<0,0001) e área da lesão (Ws) (p=0,045), sendo as piores condições encontradas encontradas em GO. Observou-se que houve diferença significativa entre a perda mineral e quantidade de biofilme dentário por fluorescência entre os grupos, mas não entre T0 e T1. Diante dos resultados, podese concluir que indivíduos portadores de síndrome metabólica, comparado com os eutróficos, apresentam maior número de lesões cariosas antes e após a cirurgia bariátrica. No presente estudo a cirurgia bariátrica não interferiu na progressão das lesões cariosas, todavia, destaca-se a necessidade de abordagem multiprofissional e contínua, atuando na prevenção de doenças e atenção odontológica.(AU)

Obesity and the metabolic syndrome have increased in alarming proportions at world level. Apart from systemic consequences, obesity and its comorbidities have also been related to the oral condition. The aim of this study was to identify the caries lesion progression, presence of dental biofilm, the salivary flow and tongue coating in eutrophic individuals, being evaluated in two moments and individuals with metabolic syndrome before and after undergoing bariatric surgery. The sample consisted of 150 individuals divided into two groups: Control Group (CG: 75) and Obese Group (OG): 75, both evaluated in T0 and T1; CG being evaluated six months after T0, and EG, 6 months after bariatric surgery. Anthropometric assessment of individuals was made by means of BMI and waist circumference measurement. The ICDAS II and DMFT indices were used for evaluating the progression of dental caries. The Quantitative Light-induced Fluorescence (QLF) method, for evaluating mineral loss on the smooth tooth surfaces and the presence for dental biofilm. The stimulated salivary flow was evaluated in mL/min. The Winkel tongue coating index (WTCI) was used to evaluate the presence of tongue coating. For statistical analysis, the Chi- Square, Fishers Exact, Kruskal-Wallis and Multiple Logistic Regression tests were used, adopting a significance level of 5%. The results showed statistical difference between the groups: CG presented a higher; number of healthy teeth (p=0.038) and teeth without changes in enamel (p=0.005) when compared to OG. When comparing CG and EG after the second evaluation (T1), statistically significant difference was verified in relation to DMFT (p<0.0001), restored teeth (p<0.0001) and lesion area (Ws) (p=0.045), being the worst conditions found in OG. It was observed that there was a significant difference between mineral loss and the quantity dental biofilm by fluorescence between groups, but not between T0 and T1. In view of the results, the authors concluded that patients with metabolic syndrome, compared to eutrophic, have a higher number of caries lesions before and after bariatric surgery. In the present study, bariatric surgery did not influence in caries lesion progression, however, highlights the necessity to a continuous multi professional approach to acting in the prevention of diseases and dental care.(AU)

Assessment of Oral Conditions and Quality of Life in Morbid Obese and Normal Weight Individuals: A Cross-Sectional Study.

The aim of this study was to identify the impact of oral disease on the quality of life of morbid obese and normal weight individuals. Cohort was composed of 100 morbid-obese and 50 normal-weight subjects. Dental caries, community periodontal index, gingival bleeding on probing (BOP), calculus, probing pocket depth, clinical attachment level, dental wear, stimulated salivary flow, and salivary pH were used to evaluate oral diseases. Socioeconomic and the oral impacts on daily performances (OIDP) questionnaires showed the quality of life in both groups. Unpaired Student, Fisher's Exact, Chi-Square, Mann-Whitney, and Multiple Regression tests were used (p<0.05). Obese showed lower socio-economic level than control group, but no differences were found considering OIDP. No significant differences were observed between groups considering the number of absent teeth, bruxism, difficult mastication, calculus, initial caries lesion, and caries. However, saliva flow was low, and the salivary pH was changed in the obese group. Enamel wear was lower and dentine wear was higher in obese. More BOP, insertion loss, and periodontal pocket, especially the deeper ones, were found in obese subjects. The regression model showed gender, smoking, salivary pH, socio-economic level, periodontal pocket, and periodontal insertion loss significantly associated to obesity. However, both OIDP and BOP did not show significant contribution to the model. The quality of life of morbid obese was more negatively influenced by oral disease and socio-economic factors than in normal weight subjects.

Periodontal status and pathogenic bacteria after gastric bypass: a cohort study.

AIM: The aim this study was to evaluate the influence of gastric bypass surgery (GBS) on periodontal disease and quantify the periodontopathogenic bacteria in patients undergoing this surgery. MATERIAL AND METHODS: This prospective study was composed of 50 patients who underwent bariatric surgery and the data collection was performed in three periods pre-operative, 6 (6M) and 12 months (12 M) postoperative. The oral clinical examination to assess periodontal disease; gingival fluid sample collection for quantification of the periodontopathogenic bacteria Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Prevotella intermedia using q-PCR; body mass index (BMI) and for collection of the individual's health-related data from medical files. RESULTS: There was a significant reduction in serum C-reactive protein (CRP) and glucose levels after surgery. The mean probing pocket depth (PPD) and clinical attachment level (CAL) increased significantly in the postoperative period of 6 months (p = 0.001). In the same period, the amount of P. gingivalis increased (p = 0.028) and the other bacteria decreased slightly (p > 0.050). In the presence of P. gingivalis, T. forsythia, T. denticola and P. intermedia, a poor periodontal condition was observed. CONCLUSION: The periodontal disease increased in severity and P. gingivalis increased after GBS. A systemic inflammation resolution due to bariatric surgery in obese subjects does not seem to affect the course of periodontal disease.

Impact of bariatric surgery on oral health conditions: 6-months cohort study.

OBJECTIVES: We evaluate oral health conditions before and after bariatric surgery. METHODS: The sample was composed of 59 patients who had undergone Roux-en-Y gastric bypass (RYGB). Salivary flow, periodontal pocket depth and dental wear were evaluated before and after 6 months of surgery. Body mass index (BMI), C-reactive protein (CRP) and glucose levels were obtained from the patient's medical files. A t-test was used for dependent samples. RESULTS: The mean BMI decreased from 49.31 ± 8.76 to 35.52 ± 8.12 kg/m(2) in 6 months after surgery (P < 0.000). Before surgery, 67% of patients had high levels of CRP and 38% higher blood glucose levels and after surgery there were significant reductions in these levels (P < 0.001). Salivary flow ranged from 0.84 to 0.95 ml/min. There was increased prevalence of periodontal pockets (P = 0.022) and mean pocket depth increased to about 0.5 mm (P < 0.001). The percentage of surfaces with dental wear in dentine was significantly higher after bariatric surgery (P = 0.002), while dental wear in enamel decreased (P = 0.019). CONCLUSIONS: Bariatric surgery may improve systemic conditions. However, it had a negative impact on oral health conditions because of an increase in periodontal disease and dental wear.

Manifestações bucais em pacientes portadores de Diabetes Mellitus: uma revisão sistemática / Oral manifestations in patients with Diabetes Mellitus: a systematic review

Objetivo: O objetivo deste estudo foi realizar uma revisão sistemática da literatura sobre a associação entre o Diabetes Mellitus e as manifestações bucais. Método: Os métodos aplicados incluíram estratégia de busca na literatura e critérios de inclusão e exclusão para a seleção dos artigos a serem adotados. As bases de dados incluídas foram PubMed, SciElo, BBO e LILACS, até setembro de 2011. Os artigos selecionados investigaram a associação ou não do Diabetes Mellitus com manifestações bucais, excluindo a doença periodontal. Resultado: De 1164 artigos encontrados, 30 deles estavam de acordo com os critérios de inclusão, podendo permanecer no estudo. As manifestações bucais foram associadas com Diabetes Mellitus em 20 estudos. Os desfechos relacionados foram candidíase, hipossalivação, líquen plano bucal, estomatite por dentadura e lesões linguais. Conclusão: Os pacientes portadores de Diabetes Mellitus estão mais predispostos a apresentar candidíase e hipossalivação, podendo agravar muito determinadas condições de saúde bucal.

Purpose: The aim of this study was to systematically review studies on the association between diabetes mellitus and oral manifestations. Method: The methods applied include a literature search strategy, inclusion and exclusion criteria for selecting the studies, characteristics of the studies were adopted. Data bases included PubMed, SciElo, BBO and LILACS until September 2011. Selected articles were related to clinical studies investigating whether or not there is an association between diabetes mellitus and oral manifestations, excluding periodontal disease. Result: Of the 1164 studies identified, 30 of them remained in the study due the inclusion criteria. The oral manifestations were associated with diabetes mellitus in 20 studies. The diseases candidiasis, hypossalivation, oral lichen planus, dentadure stomatitis and tongue lesions were related. Conclusion: Patients with diabetes mellitus are more susceptible to the candidiasis and hypossalivation, which in turn may exacerbate other oral health conditions.

Estudo transversal sobre problemas bucais em pacientes obesos mórbidos / Cross-sectional study about oral problems in morbidly obese patients

A prevalência da obesidade tem aumentado em proporções alarmantes, tornando-se um problema de saúde pública. Há relatos de uma possível relação da obesidade com a condição bucal e o objetivo do presente estudo foi identificar os problemas bucais e seu impacto na qualidade de vida de indivíduos obesos mórbidos. A amostra foi composta por 100 pacientes obesos mórbidos (grupo obeso) e 50 indivíduos eutróficos (grupo controle), atendidos no Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da USP. Os pacientes responderam um questionário socioeconômico e outro de qualidade de vida, o Oral Impacts on Daily Performances (OIDP) e, em seguida, foi realizado o exame bucal. O índice International Caries Detection & Assessment System II (ICDAS II) foi utilizado para avaliar a cárie dentária; o Índice Periodontal Comunitário (IPC) e Perda de Inserção Periodontal (PIP) avaliaram as condições periodontais e o Índice de Desgaste Dentário (IDD) para avaliar a prevalência e severidade do desgaste. Ainda foram avaliados o fluxo salivar estimulado e o pH da saliva. Para análise estatística foram utilizados os testes T de Student, Qui-quadrado e Regressão Linear Múltipla. A média do OIDP foi de 13,06 ± 23,27 para o grupo obeso e 4,36 ± 10,92 para o grupo controle, indicando maior impacto da condição bucal no desempenho diário dos obesos (p=0,060). O grupo obeso apresentou maior prevalência e severidade de cárie (p=0,041) e de doença periodontal (p<0,050). Foi observada maior severidade de desgaste nos obesos (p<0,050). Ambos os grupos apresentaram fluxo salivar baixo, sendo significativamente menor entre os obesos (p=0,005). Após o ajuste da amostra, observou-se que as condições periodontais continuaram relacionadas à obesidade, enquanto que perda dentária, desgaste e fluxo salivar foram influenciados pela idade no grupo obeso e a cárie dentária pelo nível socioeconômico deste grupo. As condições de saúde bucal dos pacientes obesos mostraram-se piores...

The prevalence of obesity has increased in alarming proportions, becoming a public health problem. There are reports of a possible relationship between obesity and oral condition and the objective of this study was to identify oral problems and their impact in quality of life of morbidly obese individuals. The sample was composed of 100 morbidly obese patients (obese group) and 50 normal weight patients (control group) examined at the School of Medicine Hospital of Ribeirão Preto- USP. The subjects answered a socioeconomic and a quality of life questionnaire, the Oral Impacts on Daily Performances (OIDP) and, in the sequence the dental examination was performed. The International Caries Detection & Assessment System II (ICDAS II) was used to evaluate tooth decay, the Community Periodontal Index (CPI) and Clinical Attachment Level (CAL) evaluated periodontal conditions and the Dental Wear Index evaluated the prevalence and severity of wear. Also were evaluated the stimulated salivary flow and the Ph of saliva. Students t test, Chi- Square and Multiple Regression were used for statistical analysis. The average OIDP was 13.06 ± 23.27 for the obese group and 4.36 ± 10.92 for the control group, indicating higher impact of oral health in the quality of life of obese individuals (p=0.060). The obese group showed greater prevalence and severity of decay (p=0.041) and of periodontal disease (p< 0.050). Both groups showed low salivary flow and it was significantly lower among obese (p=0.005). After adjustment of the sample, it was observed that the periodontal conditions related to obesity continued, while that tooth loss, dental wear and salivary flow were influenced by age in obese group and the dental decay by the socioeconomic level of this group. The oral health condition of obese patients appeared worse when compared to eutrophic, mainly regarding periodontal disease, which contributed to a negative impact on quality of life.