ABSTRACT
A 12-y-old, castrated male Weimaraner dog was presented for a wellness examination. A 7-cm, firm mass was palpated on the left, ventral, mid-lateral neck. The neck mass was removed surgically and submitted for histopathology. A thyroid carcinoma was diagnosed based on microscopic examination. Immunohistochemistry for chromogranin-A, calcitonin, and thyroglobulin identified dual immunoreactivity of the latter two, and a final diagnosis was of a well-differentiated, compact, mixed medullary and follicular cell thyroid carcinoma. These neoplasms are rare in humans and have not been reported in dogs, to our knowledge.
Subject(s)
Adenocarcinoma, Follicular , Carcinoma, Medullary , Dog Diseases , Thyroid Neoplasms , Humans , Dogs , Male , Animals , Thyroglobulin , Calcitonin , Carcinoma, Medullary/pathology , Carcinoma, Medullary/ultrastructure , Carcinoma, Medullary/veterinary , Chromogranins , Adenocarcinoma, Follicular/diagnosis , Adenocarcinoma, Follicular/surgery , Adenocarcinoma, Follicular/veterinary , Thyroid Neoplasms/surgery , Thyroid Neoplasms/veterinary , Thyroid Neoplasms/pathology , Dog Diseases/diagnosis , Dog Diseases/surgery , Dog Diseases/pathologyABSTRACT
A red ruffed lemur (Varecia rubra) from a zoo in Louisiana, USA, was euthanized for worsening paresis. Brain and spinal cord histology identified eosinophilic meningoencephalomyelitis with intralesional adult Angiostrongylus sp. nematodes. PCR and sequencing confirmed A. cantonensis infection, indicating this parasite constitutes an emerging zoonosis in the southeastern United States.
Subject(s)
Angiostrongylus cantonensis , Lemuridae , Strongylida Infections , Angiostrongylus cantonensis/genetics , Animals , Louisiana/epidemiology , Strongylida Infections/diagnosis , Strongylida Infections/epidemiology , Strongylida Infections/veterinary , Zoonoses/parasitologyABSTRACT
A 4-y-old, spayed female, mixed-breed domesticated rabbit (Oryctolagus cuniculus domesticus) was presented because of progressive bilateral exophthalmos, with a large mediastinal mass in the cranial thorax. Palliative radiation therapy was elected, and 4 fractions of 5 Gy were delivered twice weekly under general anesthesia using 3-dimensional conformal radiation therapy for a total dose of 20 Gy, guided by an on-board cone beam CT scan. Quality-of-life and respiratory rate improved before sudden death that followed an episode of dyspnea. The overall survival time following initial diagnosis was 93 d, with 68 d after the first dose of radiation. An autopsy was performed, and the mass was diagnosed as a type A thymoma. The diagnosis was confirmed with positive immunohistochemical labeling of the neoplastic cells for cytokeratin 5/6 and cytokeratin 7.