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Chem Commun (Camb) ; 60(27): 3721-3724, 2024 Mar 28.
Article in English | MEDLINE | ID: mdl-38482771

ABSTRACT

Here, we report a DNA tetrahedron dimer for dual membrane protein logic recognition and interaction inhibition. The DNA tetrahedron dimer not only detects dual proteins that are both overexpressed on target cells in "AND" logic, but also inhibits protein interaction by steric hindrance to suppress cell proliferation, offering new insights for cancer cell diagnosis and treatment.


Subject(s)
DNA , Membrane Proteins , Logic
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