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2.
Gan To Kagaku Ryoho ; 46(13): 2216-2218, 2019 Dec.
Article in Japanese | MEDLINE | ID: mdl-32156883

ABSTRACT

The rate of local and anastomotic recurrence after curative resection for colon cancer is quite low, at 2.1%. We describe an anastomotic recurrence that rapidly increased after transverse colon cancer resection. An 80-year-old man underwent laparoscopic- assisted transverse colon resection with D3 lymph node dissection. The pathological diagnosis was pT4aN1bM0, pStage Ⅲb. We diagnosed the patient with anastomotic recurrence and liver metastasis 4 months after the procedure based on PET-CT findings. Partial colon resection(small intestine and stomach combined)was performed at 6 months after the procedure. The patient's quality of life(QOL)was reduced by complications after the second procedure and continuing with chemotherapy became difficult. Although the prognosis of curative resection of local and anastomotic recurrence after transverse colon cancer surgery can be good, combined resection of an adjacent organ can result in a decline in patient QOL. Surgical intervention should be minimally invasive and neo-adjuvant chemotherapy might offer 1 option.


Subject(s)
Colon, Transverse , Colonic Neoplasms , Aged, 80 and over , Colon, Transverse/surgery , Colonic Neoplasms/surgery , Humans , Male , Neoplasm Recurrence, Local , Positron Emission Tomography Computed Tomography , Quality of Life
3.
Gan To Kagaku Ryoho ; 45(13): 1830-1832, 2018 Dec.
Article in Japanese | MEDLINE | ID: mdl-30692368

ABSTRACT

A woman in her early 50s underwent abdominoperineal resection with left lateral lymph node resection for advanced rectal cancer. The pathological diagnosis was RC, RbP, well-differentiated, type 5, 65×47mm, pT3(A), pN0(0/40), M0, pStage Ⅱ. The local recurrence discovered under the perineal skin 2 months later was treated by resecting the tumor and both inguinal lymph nodes. Adjuvant chemotherapy containing UFT plus LV was also initiated for 6 months. She remains free of recurrence 1 year after resection of the local recurrence.


Subject(s)
Proctectomy , Rectal Neoplasms , Female , Humans , Lymph Node Excision , Lymphatic Metastasis , Middle Aged , Neoplasm Recurrence, Local , Rectal Neoplasms/surgery
4.
Gan To Kagaku Ryoho ; 44(12): 1420-1422, 2017 Nov.
Article in Japanese | MEDLINE | ID: mdl-29394654

ABSTRACT

The patient was a man in his early 30s. He underwent sigmoidectomy with D3+ #216 for advanced sigmoid colon cancer with metastatic para-aortic lymph nodes. The pathological diagnosis was colon cancer(S), type 2, moderately differentiated, pT4a(SE), pN3(19/33), pM1a(LYM), pStage IV , KRAS wild-type, EGFR(+). He received FOLFOX plus bevacizumab(Bmab) as adjuvant chemotherapy. One year postoperatively, he experienced recurrence as multiple lung metastases. FOLFIRI plus panitumumab, SOX plus Bmab, CapeOX, nivolumab and FOLFIRI plus ramucirumab were then administered. The patient has survived for 4 years and 11 months from operation.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Aorta/pathology , Sigmoid Neoplasms/pathology , Sigmoid Neoplasms/therapy , Adult , Aorta/surgery , Combined Modality Therapy , Fatal Outcome , Humans , Lymph Nodes , Lymphatic Metastasis , Male , Neoplasm Staging , Time Factors
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