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1.
J Ultrasound Med ; 40(4): 771-778, 2021 Apr.
Article in English | MEDLINE | ID: mdl-32856750

ABSTRACT

OBJECTIVES: To investigate the B-mode ultrasound (US) features and elasticity of the Achilles tendon in patients with chronic kidney disease (CKD) using US elastography and to compare them with those of healthy individuals. METHODS: From March 2019 through May 2019, 30 consecutive patients with variable stages of CKD and 30 healthy individuals were prospectively included in this study. Ultrasound and strain elastographic examinations were performed on both Achilles tendons of all individuals. Degrees of tendinopathy, if existed, were classified as defined by Archambault et al (J Clin Ultrasound 1998; 26:335-339), and thicknesses were documented with US. Strain ratios (SRs) were calculated by measuring the strain values from the Achilles tendon and Kager fat pad. Statistical differences in the SRs of Achilles tendons between the control group and patients with CKD were calculated. RESULTS: The 30 patients with CKD ranged in age from 24 to 73 years, and the 30 healthy individuals ranged in age from 25 to 78 years. Both distal and left middle thirds of the Achilles tendons were thicker in patients with CKD than in healthy individuals (P < .05). The mean SRs ± SDs in the patient group (4.71 ± 0.95 and 4.85 ± 1.47 on the right and left, respectively) were significantly higher (P < .05) than in healthy individuals (2.31 ± 0.42 and 2.65 ± 0.55 on the right and left), which indicated an increased stiffness of Achilles tendons in the patient group. CONCLUSIONS: As a semiquantitative and noninvasive imaging modality, strain elastography has the potential to detect the morphologic and elasticity changes of Achilles tendons in patients with CKD, which may give an opportunity to help physicians predict possible leading partial or complete tears.


Subject(s)
Achilles Tendon , Elasticity Imaging Techniques , Renal Insufficiency, Chronic , Tendinopathy , Achilles Tendon/diagnostic imaging , Adult , Aged , Humans , Middle Aged , Renal Insufficiency, Chronic/complications , Renal Insufficiency, Chronic/diagnostic imaging , Ultrasonography
2.
Ultrasound Q ; 37(2): 155-160, 2020 Sep 25.
Article in English | MEDLINE | ID: mdl-32976319

ABSTRACT

ABSTRACT: We aimed to evaluate the efficiencies of quantitative shear-wave elastography, fine-needle aspiration (FNA) biopsy and American College of Radiology (ACR)-thyroid imaging reporting and data system (TIRADS) scoring system in determining the malignity potential of solid thyroid nodules. In period between September 2014 and January 2016, 191 solid thyroid nodules of 189 patients were enrolled in this study. The mean shear wave velocities of the nodules were recorded by acoustic radiation force impulse method. All nodules were classified according to ACR-TIRADS scoring system and underwent FNA procedure. The cytopathologic results (after FNA) were benign in nature, atypical-cytology/suspiciously malign and highly suspicious of malignity in 117, 28, and 21 nodules, respectively. The specimen from FNA was insufficient in 25 nodules. Thirty-four nodules of 33 enrolled patients were operated, and the efficiencies of shear wave elastography, FNA, and ACR-TIRADS procedures were statistically analyzed; relying on the histopathologic results, the shear-wave elastography had 83.3% sensitivity, 93.7% specificity (with a cutoff value of 2,74 m/s), the FNA had 94.4% sensitivity, 87.5% specificity, and ACR-TIRADS had 88.2% sensitivity, 94.1 specificity in determining malignant tyroid nodules (P < 0.005). Quantitative shear wave elastography is concluded to be an effective, noninvasive, and practical imaging modality with a lesser sensitivity and specificity values than TIRADS unless a lower sensitivity but a higher specificity values than FNA (93.7% vs 87.5%) in considering the malignity potential of solid thyroid nodules.


Subject(s)
Elasticity Imaging Techniques , Radiology , Thyroid Neoplasms , Thyroid Nodule , Biopsy, Fine-Needle , Humans , Retrospective Studies , Thyroid Nodule/diagnostic imaging , United States
3.
Anat Histol Embryol ; 49(1): 60-66, 2020 Jan.
Article in English | MEDLINE | ID: mdl-31486129

ABSTRACT

This study was carried out to determine the morphometric values of the pelvic cavity, the cranial and caudal pelvic aperture by three-dimensional (3D) reconstruction of the images obtained by computed tomography in adult Van Cats and to show the differences between these indicators in both genders. A total of 16 adult Van Cats, eight male and eight female, were used in the study. Animals were anesthetized with ketamine-xylazine combination and were scanned by computerized tomography. Images of the pelvic cavity were obtained. Three-dimensional reconstruction of the pelvis was performed with three-dimensional modelling program. Measurements of the diameters of the pelvic cavity, the cranial and caudal pelvic aperture were calculated from these images, and statistical analyzes were performed. Three-dimensional modelling of the pelvic cavity of Van Cats were examined between males and females. The results showed that there were significant (p < .05) differences between measurement of the pelvic inclination, the medial transverse diameter, the caudal transverse diameter and the angle between ischiatic arch. In addition, the correlations between age and weight were found statistically significant (p < .05) with the dorsal transverse diameter, the intermediate transverse diameter and the caudal transverse diameter in males. On the other hand, the correlations of age were statistically significant (p < .01) with the cranial pelvic aperture and the caudal pelvic aperture in females. In conclusion, some biometric values of pelvic cavity were observed to be statistically different in Van Cats.


Subject(s)
Pelvis/anatomy & histology , Animals , Cats , Female , Imaging, Three-Dimensional/veterinary , Male , Tomography, X-Ray Computed/veterinary
4.
Forensic Sci Int ; 303: 109955, 2019 Oct.
Article in English | MEDLINE | ID: mdl-31541936

ABSTRACT

Sex estimation is an essential step in the process of the identification of the skeletal remains in forensic anthropology since it reduces the number of possible matches by half. In this study, sex estimation with 21 sacral and coccygeal metric parameters obtained from Computerized Tomography images of a Turkish population which consists of 480 patients that are equalized according to their sexes and ages, is performed. Univariate discriminant analysis, linear discriminant function analysis, stepwise discriminant function analysis, and multilayer perceptron neural networks are used in this study. A maximum of 67.1% accuracy for univariate discriminant analysis, 82.5% for linear discriminant function analysis, 78.8% for stepwise discriminant function analysis, and 86.3% for multilayer perceptron neural networks, were achieved. Although it does not reach an acceptable accuracy rate of 95% or more for sacrum and coccyx, sex estimation with neural networks is a promising field of research in corpses where identification is otherwise not possible, and further studies with other bones and with new techniques might give useful information.


Subject(s)
Coccyx/diagnostic imaging , Discriminant Analysis , Neural Networks, Computer , Sacrum/diagnostic imaging , Sex Determination by Skeleton/methods , Tomography, X-Ray Computed , Adult , Aged , Female , Forensic Anthropology , Humans , Male , Middle Aged , Turkey , Young Adult
5.
J Ultrasound ; 22(4): 447-452, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31482292

ABSTRACT

In this study, a comparison is made of the findings of B-mode ultrasound and ultrasound elastography with the Lens Opacities Classification (LOCS) grade in patients with senile cataracts. A total of 74 patients with cataracts and 32 age-matched healthy volunteers as the control group were evaluated in the departments of ophthalmology and radiology between 2016 and 2017. In the patient group, cataracts were graded according to LOCS, and B-mode sonographic appearance and elasticity measurements were recorded, after which the cataract grade and sonoelastography/B-mode ultrasound findings were compared using statistical methods. Among the 74 patients with cataracts, 38 were females (51.4%) and 36 were males (48.6%), and the mean age was 62.05 ± 7.95 (43-78) years. A Chi-square test revealed a significant relationship between ultrasound echogenicity of cataract and grade of cataract (p < 0.005). The ultrasound elastography revealed a mean shear-wave velocity of 2.90 m/s ± 0.371 (2.13-3.53) among patients with grade 3 cataracts, 3.1 m/s ± 0.45 (2.26-3.98) among patients with grade 4, 3 m/s ± 0.58 (2.35-4.60) among patients with grade 5 and 3 m/s ± 0.528 (2.31-4.50) among patients with grade 6 cataracts, and 3 m/s ± 0.258 (2.36-3.58) among the normal subjects. No statistically significant difference was noted in the analysis of variance (p > 0.005). While cataract grade and B mode echogenicity were directly proportional, there was no significant difference in lens elasticity.


Subject(s)
Cataract/classification , Adult , Aged , Case-Control Studies , Cataract/diagnosis , Cataract/diagnostic imaging , Elasticity Imaging Techniques , Female , Humans , Lens, Crystalline/diagnostic imaging , Male , Middle Aged , Ultrasonography
6.
Ultrasound Q ; 35(2): 164-168, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30724867

ABSTRACT

The aim of the study was to investigate the efficacy of shear-wave elastography (SWE) in the differentiation of transudative and exudative pleural effusions. This monocentric study comprised 60 cases (17 transudative, 43 exudative).Transthoracic SWE was performed in 60 cases for whom to use thoracentesis for the pleural fluid analysis was planned. The mean SWE values of each patient were recorded, and the correlation between the biochemical analysis results of pleural fluid after thoracentesis and SWE findings was evaluated. The effusion SWE values and biochemical analysis results were compared. Of the 60 patients who participated in this study, 32 (53.4) were male and 28 (46.6%) were female. The mean ± SD age was 59 ± 17.09 years (range = 21-89 years). Simultaneous serum biochemical analysis was performed for the patients with PE. The mean ± SD shear-wave velocity value of the transudative fluid was calculated 2.29 ± 0.41 (1.6-2.94), whereas the mean ± SD shear-wave velocity value of the exudative pleural fluid was calculated as 3.29 ± 0.63 (2.01-4.88) (P < 0.001). The receiver operating characteristic analysis showed that sensitivity and specificity were found as 91% and 76.5%, respectively, when the cutoff value was selected as 2.52 m/s in the differentiation of the transudative and exudative effusions.Shear-wave elastography may help in the differentiation of transudative and exudative of the pleural effusions.


Subject(s)
Elasticity Imaging Techniques/methods , Pleural Effusion/diagnostic imaging , Adult , Aged , Aged, 80 and over , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Pleural Cavity/diagnostic imaging , Reproducibility of Results , Sensitivity and Specificity , Young Adult
7.
J Matern Fetal Neonatal Med ; 32(15): 2481-2485, 2019 Aug.
Article in English | MEDLINE | ID: mdl-29480138

ABSTRACT

OBJECTIVE: In this study, we aimed to evaluate the elasticities of fetal placentas with a single umbilical artery using the Virtual Touch Tissue Quantification (VTTQ) technique. MATERIALS AND METHODS: Pregnant women with fetuses with a single umbilical artery (SUA) and pregnant women with fetuses having three vessel cord (3VC) at 18-22 weeks of gestation were enrolled in the research. The placentas were evaluated and divided into three equal parts as the inner 1/3 of the placenta (fetal edge), the outer 1/3 of the placenta (maternal edge) and the central 1/3 of the placenta (central part). Shear-wave velocity (SWV) measurements were used in the elastographic evaluation of placentas by VTTQ. RESULTS: Forty pregnant women were included in the study (n = 20 SUA, n = 20 three vessel cord pregnant women). The placental Acoustic Radiation Force Impulse (VTTQ) of the placenta regarding SWV measurement values of the fetal edge of the placenta in the fetuses with SUA and the control group were 0.876 and 0.957 m/sec, respectively. A significant statistical difference was found between the groups regarding the measurement of the stiffness of fetal placenta (p = 0.021). There was no significant difference between the measured stiffness values of the central or outer region of the placentas. CONCLUSIONS: In this study, we found lower SWV scores for the fetal edge of the placenta with SUA. This finding may reflect tissue elasticity level, and we hope that the use of the VTTQ technique may contribute to predicting the pregnancy-related morbidities of fetuses with SUA in the future.


Subject(s)
Elasticity Imaging Techniques , Placenta/diagnostic imaging , Single Umbilical Artery/diagnostic imaging , Ultrasonography, Prenatal/methods , Adult , Female , Humans , Pregnancy , Prospective Studies , Young Adult
8.
Ultrasound Q ; 34(4): 233-237, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30169488

ABSTRACT

In this study, the effectiveness of transthoracic ultrasound elastography in the benign and malign distinction of subpleural/pleural solid lesions was investigated.Between July 2015 and December 2016, 33 consecutive patients with subpleural solid lesions detected via computed tomography (CT) of the thorax were identified and prospectively included in this study. The average for each lesion's shear wave velocity (SWV) value was detected, and benign and malignant lesions' SWV values are statistically compared. The CT and pathology results were used as a reference to compare these values. A receiver operating characteristic analysis was used to determine the cutoff value for benign/malignant neoplasms.The 33 patients (10 female, 23 male) included in the study had a mean age of 56.2 ± 15.40 years (range, 17-84 years), and the mean SWV value of the lesions in 13 (39%) cases evaluated benign after a CT scan, histopathological examination, or both 2.18 ± 0.49 m/s. The mean SWV value of the lesions which were histopathologically diagnosed as malign in 23 (61%) cases was 3.50 ± 0.69 m/s. (P < 0.001). When the cutoff value was set as 2.47 m/s for the SVW value, sensitivity and specificity were determined to be 97.7%.The present study has shown that transthoracic ultrasound shear wave elastography can be an effective radiological examination method in the benign and malign differentiation of subpleural lesions and has the potential for use in the routine clinical application of transthoracic ultrasound elastography, a noninvasive method for evaluating the malignancy potentials of such lesions.


Subject(s)
Carcinoma, Large Cell/diagnostic imaging , Carcinoma, Small Cell/diagnostic imaging , Elasticity Imaging Techniques/methods , Lung Neoplasms/diagnostic imaging , Neoplasms, Squamous Cell/diagnostic imaging , Sarcoma/diagnostic imaging , Adolescent , Adult , Aged , Aged, 80 and over , Diagnosis, Differential , Female , Humans , Lung/diagnostic imaging , Male , Middle Aged , Prospective Studies , Reproducibility of Results , Sensitivity and Specificity , Young Adult
9.
Med Ultrason ; 20(2): 141-147, 2018 May 02.
Article in English | MEDLINE | ID: mdl-29730678

ABSTRACT

AIMS: To evaluate the reliability of testicular stiffness quantification using shear wave elastography in predicting the fertility potential of males and for the pre-diagnosis of disorders based upon sperm quantification. MATERIAL AND METHODS: One hundred males between the ages of 19-49 years (mean age of 28.77±6.11), ninety of whom with complaints of infertility, were enrolled in this prospective study. Scrotal grey-scale, Doppler ultrasound (US), and mean testicular shear wave velocity quantifications (SWVQs) were performed. The volumes of testes, as well as the grade of varicocele if present, were recorded. The mean shear wave velocity values (SWVVs) of each testis and a mean testicular SWVV for each patient were calculated. The semen-analyses of patients were consecutively performed. RESULTS: There were significant negative correlations between the mean testicular SWVVs of patients and their sperm counts or the testis volumes (r=-0.399, r=-0.565; p<0.01, respectively). A positive correlation was found between testicular volumes and sperm counts (r=0.491, p<0.01). The cut-off values regarding mean testicular SWVV to distinguish normal sperm count from azoospermia and oligozoospermia were 1.465 m/s (75.0% sensitivity and 75.0% specificity) and 1.328 m/s (64.3% sensitivity and 68.2% specificity), respectively, and the value to distinguish oligozoospermia from azoospermia was 1.528 m/s (66.7% sensitivity, 60.7% specificity). CONCLUSION: The mean testicular SWVQ using the ARFI shear wave technique was a reliable, non-invasive and acceptably stable method for predicting male infertility, especially related to sperm count issues.


Subject(s)
Elasticity Imaging Techniques/methods , Infertility/diagnostic imaging , Infertility/pathology , Testis/diagnostic imaging , Testis/pathology , Adult , Fertility , Humans , Infertility/complications , Male , Middle Aged , Organ Size , Prospective Studies , Reproducibility of Results , Sensitivity and Specificity , Ultrasonography, Doppler , Varicocele/complications , Varicocele/diagnostic imaging , Varicocele/pathology , Young Adult
10.
World Neurosurg ; 118: 86-87, 2018 Oct.
Article in English | MEDLINE | ID: mdl-29705229

ABSTRACT

A 55-year-old male who complained of frequent back pain accompanied by increasing weakness in the lower extremities was admitted to our hospital's Neurosurgery Department. No additional disease was in his history. Magnetic resonance imaging of the thoracic area, anterior epidural space, and paravertebral area revealed an approximately 55 × 9 mm lymphoma pressuring the spinal cord from the anterior. It was fusiformed with a dural tail, hypointense on sagittal T1-weighted imaging series, and hypointense on sagittal T2-weighted imaging series compared with the spinal cord, showing contrast enhancement. After gadolinium application, an extra-axial mass lesion was detected. The lesion was surgically removed from the patient, whom we thought had meningioma on the basis of radiology. However, histopathology resulted in the diagnosis of diffuse large B-cell non-Hodgkin lymphoma.


Subject(s)
Magnetic Resonance Imaging , Meningeal Neoplasms/surgery , Meningioma/diagnostic imaging , Meningioma/surgery , Humans , Lymphoma, Large B-Cell, Diffuse/pathology , Magnetic Resonance Imaging/methods , Male , Meningeal Neoplasms/diagnostic imaging , Meninges/pathology , Middle Aged , Postoperative Period , Thoracic Vertebrae/pathology
12.
J Obstet Gynaecol ; 38(7): 911-915, 2018 Oct.
Article in English | MEDLINE | ID: mdl-29564950

ABSTRACT

We aimed to evaluate the efficiency of placental elasticity in predicting a placental invasion anomaly with the Virtual Touch Quantification (VTQ) technique. Pregnant women in the third trimester with suspected placental invasion anomaly were enrolled into the research (n = 58). The placenta was evaluated and divided into three equal parts as foetal edge (inner 1/3 of placenta), maternal edge (outer 1/3 of placenta) and the central part (central 1/3 of placenta). Shear wave velocity (SWV) measurements were used in the elastographic evaluation of placentas by VTQ. We performed the measurements at the different regions of placenta for sampling the variety areas of the placenta. Acoustic Radiation Force Impulse (ARFI) Elastography scores were significantly higher in the group in which an invasion was detected during the surgery of patients with preoperative placental invasion suspicion. A significant difference in the measurements of the inner, central and outer third of the placenta between the groups was found (p < .001). In this study, we have shown higher SWV scores of placental measurements of the patients with preoperative suspected anomalies and an invasion detected during their surgery. These findings may reflect an event at the tissue elasticity level and we hope that the use of the VTQ technique may contribute to an early prediction of placental invasions before surgery in the future via new research. Impact statement What is already known on this subject? Placenta invasion anomalies (PIA's) are characterized by haemorrhages which can threat the mother's life. Placental invasion anomalies are among the most important causes of maternal mortality and morbidity. Early diagnosis is very important condition in reducing the mortality and morbidity. Gray scale ultrasonography (US) is mostly used in early diagnosis of PIA's. Acoustic radiation force impulse elastography (ARFI) is a new elastographic ultrasonography technic. We aimed to evaluate a new method in the early diagnosis of PIA's using ARFI technique. There is no study in the diagnosis of PIA's by ARFI in the literature to our knowledge. We think that this original study will contribute to the literature. What do the results of this study add? We showed the accuracy of ARFI in determination of PIA's. ARFI scores were significantly higher in the group in which invasion was detected during surgery of patients with preoperative placental invasion suspicion. What are the implications are of these findings for clinical practice and/or further research? Our findings may reflect an event at the tissue elasticity level and we hope that the use of VTQ technique may contribute to early predict of placental invasions before surgery in the future via new researches. Early diagnosis of placental invasion anomalies may reduce mortality and morbidity.


Subject(s)
Elasticity Imaging Techniques/methods , Elasticity , Placenta Accreta/diagnosis , Placenta/diagnostic imaging , Adult , Female , Humans , Placenta/pathology , Predictive Value of Tests , Pregnancy , Pregnancy Trimester, Third , Prospective Studies
13.
Med Sci Monit ; 24: 855-862, 2018 Feb 11.
Article in English | MEDLINE | ID: mdl-29428963

ABSTRACT

BACKGROUND In the present study, the role and efficiency of strain elastography (SE) were evaluated in diagnosis and staging of acute appendicitis in pediatric patients. MATERIAL AND METHODS We enrolled 225 pediatric patients with suspected clinical and laboratory findings of acute appendicitis. Gray-scale sonographic findings were recorded and staging was made by the colorization method of SE imaging. Appendectomy was performed in all patients and the results of the surgical pathology were compared with the imaging findings. The sensitivity, specificity, and accuracy of SE imaging were determined in terms of evaluating the "acute appendicitis". RESULTS Sonographic evaluation revealed acute appendicitis in 100 patients. Regarding the SE analysis, cases with appendicitis were classified into 3 groups as: mild (n=17), moderate (n=39), and severe (n=44). The pathological evaluation revealed 95 different stages of appendicitis and normal appendix in 5 cases: acute focal (n=10), acute suppurative (n=46), phlegmonous (n=27), and perforated (n=12), regarding the results of surgical pathology. Five patients with pathologically proven "normal" appendix were noted as "mild stage appendicitis" based on gray scale and SE analysis. In total, when gray-scale and SE results were compared with pathology results regardless of the stage of appendicitis, sensitivity, specificity, positive predictive value, negative predictive value, and accuracy rates were 96%, 96%, 95%, 96.8%, and 96%, respectively. No statistically significant difference was detected between other groups (P<0.05). CONCLUSIONS In acute appendicitis, the use of SE imaging as a supportive method for the clinical approach can be useful in diagnosis, and its results are closely correlated with the histopathologic stage of appendix inflammation.


Subject(s)
Appendicitis/diagnosis , Appendicitis/physiopathology , Elasticity Imaging Techniques , Acute Disease , Adolescent , Appendicitis/diagnostic imaging , Appendix/diagnostic imaging , Appendix/pathology , Child , Child, Preschool , Female , Humans , Infant , Male
14.
J Med Ultrason (2001) ; 45(3): 453-459, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29330689

ABSTRACT

OBJECTIVES: The aim of the present study was to quantify the stiffness of the median nerve (MN) at the carpal tunnel inlet by acoustic radiation force impulse (ARFI) elastography and to evaluate whether ARFI can be used in diagnosis and staging of carpal tunnel syndrome (CTS). METHODS: Sonographic examinations of 96 wrists in 50 patients were included in the study. The cross-sectional area and stiffness of the MN were quantitatively measured by B-mode ultrasonography (USG) and ARFI. The findings of CTS were assigned to four groups: (I) normal (n = 21), (II) mild (n = 39), (III) moderate (n = 38), and (IV) severe (n = 19). The differences between CTS patients and controls and the differences in electrodiagnostic tests among subgroups were statistically compared. ROC analysis was performed to determine the cut-off values between subgroups. RESULTS: Bilateral CTS was present in 46 patients (92 wrists) and unilateral CTS in four patients. Of the 96 nerves in the 50 symptomatic "idiopathic CTS" patients (48 women, 2 men; mean age 45.9 years, range 23-73 years), 39 (40.4%) were mild, 38 (39.8%) were moderate, and 19 (19.8%) were severely affected. When compared to controls, MN stiffness was significantly higher in the CTS group (P < 0.001); furthermore, it was higher in the severe or extreme severity group than the mild or moderate severity group (P < 0.001). A 3.250 m/s cut-off value on ARFI revealed sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 81, 82, 95.1, 50, and 82%, respectively. CONCLUSION: The MN stiffness measured by ARFI elastography is significantly higher in patients with CTS then in controls. ARFI elastography appears to be a highly efficient imaging modality for the diagnosis and staging of these patients.


Subject(s)
Carpal Tunnel Syndrome/diagnostic imaging , Elasticity Imaging Techniques , Adult , Aged , Elasticity , Elasticity Imaging Techniques/methods , Electrodiagnosis , Female , Humans , Male , Middle Aged , Observer Variation , Prospective Studies , ROC Curve , Severity of Illness Index , Wrist/diagnostic imaging , Wrist/physiopathology , Young Adult
15.
Neurol Neurochir Pol ; 52(1): 107-111, 2018.
Article in English | MEDLINE | ID: mdl-29162292

ABSTRACT

IgA vasculitis (IgAV) is a leukocytoclastic vasculitis and characterized by involvement of small vessels in skin, gastrointestinal system, joints, kidneys, and less frequently other organs. It is the commonest vasculitis in childhood and etiology is not completely known. Neurological manifestations of IgAV are very rare and usually seen in patients with severe hypertension or as an uncommon feature such as peripheral neuropathy. Posterior reversible encephalopathy syndrome (PRES) is a clinic-radiologic entity characterized with temporary vasogenic edema developing typically in posterior circulation of the brain and has been reported as a rare manifestation of IgAV. In this paper, a PRES case of 14-year-old male with IgAV is reported and etiopathogenesis was discussed with literature. Diagnosis was made by magnetic resonance imaging because of the existence of neurological symptoms (headache and visual loss) during the course of disease. His radiological findings have resolved with therapy. Although neurological involvement is a rare manifestation in IgAV, we recommend magnetic resonance imaging in such patients for diagnosis and evaluation of complications.


Subject(s)
Posterior Leukoencephalopathy Syndrome , Vasculitis , Adolescent , Humans , Immunoglobulin A , Magnetic Resonance Imaging , Male , Neuroimaging
16.
Ann Ital Chir ; 88: 20-25, 2017.
Article in English | MEDLINE | ID: mdl-28447586

ABSTRACT

AIM: Esophageal cancer is one of the most aggressive tumors of the gastrointestinal tract. In this study, we quantified the serum vascular endothelial growth factor-3 (VEGFR-3) expression in patients with esophageal squamous cell carcinoma (ESCC) to evaluate the role of VEGFR-3 in ESCC. MATERIALS AND METHODS: Ninety five patients with ESCC were studied. Pre-therapy and preoperative samples were stored and ELISA was used to designate the concentrations of VEGFR-3. RESULTS: The serum values of VEGFR-3 were significantly higher in patients with ESCC than in healthy donors (p<0.0001). CONCLUSIONS: The results imply a very good sensitivity of VEGFR-3 in ESCC. VEGFR-3 may be a good diagnostic biomarker for ESCC. KEY WORDS: Biomarker, ESCC, VEGFR-3.


Subject(s)
Biomarkers, Tumor/genetics , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/genetics , Esophageal Neoplasms/diagnosis , Esophageal Neoplasms/genetics , Vascular Endothelial Growth Factor Receptor-3/genetics , Adult , Aged , Biomarkers, Tumor/blood , Carcinoma, Squamous Cell/blood , Case-Control Studies , Esophageal Neoplasms/blood , Esophageal Squamous Cell Carcinoma , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Sensitivity and Specificity , Vascular Endothelial Growth Factor Receptor-3/blood
17.
Pol J Radiol ; 82: 161-164, 2017.
Article in English | MEDLINE | ID: mdl-28392853

ABSTRACT

BACKGROUND: To investigate the usefulness of popliteal artery spectral doppler findings as a complimentary approach to isolated calf vein thrombosis (DVT). MATERIAL/METHODS: We included consecutive patients presenting with symptomatic and sonographically proven acute isolated calf DVT. Patients with thrombosis of any other vein were excluded. We classified calf vein into into four main types. We investigated how many of these four vessels had DVT and compared them with respect to the pulsatility index (PI) value of the popliteal artery. RESULTS: We evaluated spectral doppler characteristics of the popliteal artery on the same side as the isolated calf vein thrombosis as well as on the opposite side. The relationship between PI values of the popliteal artery and the number of thrombosed calf veins was investigated. In patients with 1 and/or 2 thrombosed veins, the mean PI was 6.03±0.54 on the side of cDVT and 5.68±0.39 on the opposite side (p=0.008), respectively. Inpatients with 3 and/or 4 thrombosed veins, the mean PI was 8.05±0.61 on the side of cDVT and 6.34±0.47 on the opposite side (p=0.001), respectively. CONCLUSIONS: Venous doppler sonography for the evaluation of calf DVT may be limited by patient characteristics such as obesity, edema, and tenderness., Arterial PI can be used as a complimentary technique for the detection of venous thrombosis in such of cases.

18.
Radiol Oncol ; 51(1): 23-29, 2017 Mar 01.
Article in English | MEDLINE | ID: mdl-28265229

ABSTRACT

BACKGROUND: Diagnostic performance of Diffusion-Weighted magnetic resonance Imaging (DWI) and Multi-Detector Computed Tomography (MDCT) for TNM (Tumor, Lymph node, Metastasis) staging of gastric cancer was compared. PATIENTS AND METHODS: We used axial T2-weighted images and DWI (b-0,400 and b-800 s/mm2) protocol on 51 pre-operative patients who had been diagnosed with gastric cancer. We also conducted MDCT examinations on them. We looked for a signal increase in the series of DWI images. The depth of tumor invasion in the stomach wall (tumor (T) staging), the involvement of lymph nodes (nodal (N) staging), and the presence or absence of metastases (metastatic staging) in DWI and CT images according to the TNM staging system were evaluated. In each diagnosis of the tumors, sensitivity, specificity, positive and negative accuracy rates of DWI and MDCT examinations were found through a comparison with the results of the surgical pathology, which is the gold standard method. In addition to the compatibilities of each examination with surgical pathology, kappa statistics were used. RESULTS: Sensitivity and specificity of DWI and MDCT in lymph node staging were as follows: N1: DWI: 75.0%, 84.6%; MDCT: 66.7%, 82%;N2: DWI: 79.3%, 77.3%; MDCT: 69.0%, 68.2%; N3: DWI: 60.0%, 97.6%; MDCT: 50.0%, 90.2%. The diagnostic tool DWI seemed more compatible with the gold standard method (surgical pathology), especially in the staging of lymph node, when compared to MDCT. On the other hand, in T staging, the results of DWI and MDCT were better than the gold standard when the T stage increased. However, DWI did not demonstrate superiority to MDCT. The sensitivity and specificity of both imaging techniques for detecting distant metastasis were 100%. CONCLUSIONS: The diagnostic accuracy of DWI for TNM staging in gastric cancer before surgery is at a comparable level with MDCT and adding DWI to routine protocol of evaluating lymph nodes metastasis might increase diagnostic accuracy.

19.
Int J Angiol ; 25(5): e32-e36, 2016 Dec.
Article in English | MEDLINE | ID: mdl-28031648

ABSTRACT

Modern, minimally invasive techniques used to treat deep venous thrombosis, such as percutaneous mechanical thrombectomy (PMT) and catheter-directed thrombolysis, have gained worldwide acceptance. PMT has the advantage of speed and is also associated with improved outcomes, shortened hospital stays, and low complication rates. The main complications associated with PMT have been primarily due to iatrogenic vascular damage resulting in perforation, embolic occlusion, and arteriovenous fistula formation; to date, there has been no publication in the literature describing complications resulting from device failure. We present an unusual complication of PMT resulting from detachment of the catheter tip during thrombectomy and bailout technique employed.

20.
Arch Iran Med ; 19(7): 518-20, 2016 Jul.
Article in English | MEDLINE | ID: mdl-27362247

ABSTRACT

Neurofibromatosis type 2 mostly develops with multiple neoplasms of the central and peripheral nervous system and is associated with ocular abnormalities. The presented case is a 19-year-old female patient with bilateral vestibulocochlear schwannomas in both pontocerebellar corners, intradural intra-extramedullary masses, and multiple neurofibromas in the spinal canal. The clinical picture for NF-2, also called central neurofibromatosis, is completely different from von Recklinghausen disease. Untreated bilateral vestibulocochlear schwannoma may cause hydrocephalus in NF-2, and lead to death. Therefore, it is recommended to carefully monitor and treat bilateral vestibulocochlear schwannoma in accordance with its stage.


Subject(s)
Hydrocephalus/diagnostic imaging , Neurilemmoma/diagnostic imaging , Neurofibromatosis 2/diagnostic imaging , Spinal Cord Neoplasms/diagnostic imaging , Female , Humans , Hydrocephalus/etiology , Magnetic Resonance Imaging , Tomography, X-Ray Computed , Young Adult
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