ABSTRACT
La ribavirina es una molécula con actividad antiviral sobre diferentes virus. Ha encontrado su hueco en la práctica clínica de forma casi exclusiva para el tratamiento del virus de la hepatitis C, pero existen otras enfermedades que podrían beneficiarse de su empleo. Su disponibilidad para administración por vía oral, por vía intravenosa e inhalada es una característica beneficiosa. En este trabajo se realiza una revisión de las indicaciones en las principales agencias del medicamento (española, europea y americana), así como de otras posibles indicaciones, principalmente sobre fiebres hemorrágicas y coronavirus
Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitis C virus. However, there are other diseases in which it could be of benefit and it has the advantage of being suitable for oral, intravenous and inhaled administration. We conducted a review of the indications of the main drug agencies (Spanish, European and American) and other possible indications, mainly haemorrhagic fevers and coronavirus
Subject(s)
Humans , Ribavirin/therapeutic use , Hepatitis C/drug therapy , Antiviral Agents/therapeutic use , Respiratory Syncytial Viruses/drug effects , Adenoviridae/drug effects , Adenovirus Infections, Human/drug therapy , Risk FactorsABSTRACT
Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitisC virus. However, there are other diseases in which it could be of benefit and it has the advantage of being suitable for oral, intravenous and inhaled administration. We conducted a review of the indications of the main drug agencies (Spanish, European and American) and other possible indications, mainly haemorrhagic fevers and coronavirus.
Subject(s)
Antiviral Agents/therapeutic use , Ribavirin/therapeutic use , Virus Diseases/drug therapy , Viruses/drug effects , Adenoviridae Infections/drug therapy , Adenoviruses, Human/drug effects , Antiviral Agents/pharmacology , Arenaviruses, New World/drug effects , Clinical Trials as Topic , Coronavirus Infections/drug therapy , Orthohantavirus/drug effects , Hantavirus Infections/drug therapy , Hemorrhagic Fever Virus, Crimean-Congo/drug effects , Hemorrhagic Fever, American/drug therapy , Hemorrhagic Fever, Crimean/drug therapy , Humans , Lassa Fever/drug therapy , Lassa virus/drug effects , Meta-Analysis as Topic , Middle East Respiratory Syndrome Coronavirus/drug effects , Respiratory Syncytial Virus Infections/drug therapy , Respiratory Syncytial Viruses/drug effectsABSTRACT
Ribavirin is a molecule with antiviral activity against different viruses. In clinical practice, it has made its niche almost exclusively for the treatment of the hepatitis C virus. However, there are other diseases in which it could be of benefit and it has the advantage of being suitable for oral, intravenous and inhaled administration. We conducted a review of the indications of the main drug agencies (Spanish, European and American) and other possible indications, mainly haemorrhagic fevers and coronavirus.
