Respiratory Viral Testing and Influenza Antiviral Prescriptions During Hospitalization for Acute Respiratory Illnesses.

We examined respiratory viral testing and influenza antiviral prescriptions at a US tertiary care hospital. During the 2010-11 to 2012-13 influenza seasons, antiviral prescriptions among acute respiratory illness (ARI) hospitalizations were associated with viral testing (rate ratio = 15.0), and empiric prescriptions were rare (<1% of ARI hospitalizations).

Neighborhood socioeconomic status and influenza hospitalizations among children: New Haven County, Connecticut, 2003-2010.

OBJECTIVES: We examined surveillance data for disparities in pediatric influenza-associated hospitalizations according to neighborhood socioeconomic status (SES) measures in New Haven County, Connecticut. METHODS: We geocoded influenza-associated hospitalization case data from the past 7 years for children from birth to age 17 years and linked these to US Census 2000 tract-level SES data. Following the methods of Harvard's Public Health Disparities Geocoding Project, we examined neighborhood SES variables, including measures of poverty and crowding. We calculated influenza-associated hospitalization incidence by influenza season and individual case characteristics, stratified by SES measures. RESULTS: Overall, the mean annual incidence of pediatric influenza-associated hospitalization in high-poverty and high-crowding census tracts was at least 3 times greater than that in low-poverty and low-crowding tracts. This disparity could not be fully explained by prevalence of underlying conditions or receipt of influenza vaccination. CONCLUSIONS: Linkage of geocoded surveillance data and census information allows for ongoing monitoring of SES correlates of health and may help target interventions. Our analysis indicates a correlation between residence in impoverished or crowded neighborhoods and incidence of influenza-associated hospitalization among children in Connecticut.

Peridomestic Lyme disease prevention: results of a population-based case-control study.

BACKGROUND: Peridomestic Lyme disease-prevention initiatives promote personal protection, landscape modification, and chemical control. PURPOSE: A 32-month prospective age- and neighborhood-matched case-control study was conducted in Connecticut to evaluate the effects of peridomestic prevention measures on risk of Lyme disease. METHODS: The study was conducted in 24 disease-endemic Connecticut communities from 2005 to 2007. Subjects were interviewed by telephone using a questionnaire designed to elicit disease-prevention measures during the month prior to the case onset of erythema migrans. Data were analyzed in 2008 by conditional logistic regression. Potential confounders, such as occupational/recreational exposures, were examined. RESULTS: Between April 2005 and November 2007, interviews were conducted with 364 participants with Lyme disease, and 349 (96%) were matched with a suitable control. Checking for ticks within 36 hours of spending time in the yard at home was protective against Lyme disease (OR=0.55; 95% CI=0.32, 0.94). Bathing within 2 hours after spending time in the yard was also protective (OR=0.42; 95% CI=0.23, 0.78). Fencing of any type or height in the yard, whether it was contiguous or not, was protective (OR=0.54; 95% CI=0.33, 0.90). No other landscape modifications or features were significantly protective against Lyme disease. CONCLUSIONS: The results of this study suggest that practical activities such as checking for ticks and bathing after spending time in the yard may reduce the risk of Lyme disease in regions where peridomestic risk is high. Fencing did appear to protect against infection, but the mechanism of its protection is unclear.