Fruit and Vegetable Concentrate Supplementation and Cardiovascular Health: A Systematic Review from a Public Health Perspective.

Fruits and vegetables (FV) are very important for the prevention of noncommunicable diseases (NCDs), but it has been demonstrated that FV consumption is below that recommended. Several companies have worked to offer FV concentrates, but it remains unclear whether they represent a potentially effective means of reducing the burden of NCDs. The present study provides a systematic review aimed at assessing the effect of FV concentrate supplementation on select parameters that are known to be risk factors for NCDs. The systematic review was done according to the PRISMA guidelines. Relevant studies were identified through the online databases PubMed, Scopus, Web of Science, and Embase. The physiological parameters of interest were total cholesterol, low-density lipoprotein, plasmatic homocysteine, systolic blood pressure, and body mass index. Data extraction was performed in duplicate. The results of the systematic review provided input for a Markov chain simulation model aimed at estimating the public health consequences of various scenarios of FV concentrate utilization on NCDs burden. The present results suggest a positive and significant role of FV concentrate supplementation on select parameters known to affect the risk of NCDs. Such an effect might be hypothesized to turn into mitigation of the burden of those NCDs modulated by the physiological parameters analyzed in the present systematic review.

Communicating Risk Regarding Food Consumption: The Case of Processed Meat.

The present research combines real data and parameters found in recent literature that were used to design realistic scenarios demonstrating the potential effects (benefits and costs) of the World Health Organization (WHO)'s risk communication regarding the consumption of processed meat, which was proven to be associated with an increased risk of colorectal cancer (CRC) in an International Agency for Research on Cancer (IARC)/WHO report. The impact of the risk communication of processed meat consumption was simulated using Monte Carlo microsimulation models. The results showed that a 1% reduction in the number of high-level processed meat consumers may lead to a yearly decrease in CRC cases of 406.43 (IC 95%: -243.94, 1056.81), while the more extreme scenario of a 15% reduction may lead to 2086.62 fewer cases (IC 95%: 1426.66, 2746.57). On the other hand, if demand contraction in the processed meat sector resulted in a 0.1% loss in employment, one could expect 27.23 all-cause mortalities attributable to job loss (IC 95%: 16.55, 37.80). This simulation study demonstrates that caution should be taken when implementing public awareness campaigns, particularly when the prevention message is not straightforward.

High Agreement and High Prevalence: The Paradox of Cohen's Kappa.

BACKGROUND: Cohen's Kappa is the most used agreement statistic in literature. However, under certain conditions, it is affected by a paradox which returns biased estimates of the statistic itself. OBJECTIVE: The aim of the study is to provide sufficient information which allows the reader to make an informed choice of the correct agreement measure, by underlining some optimal properties of Gwet's AC1 in comparison to Cohen's Kappa, using a real data example. METHOD: During the process of literature review, we have asked a panel of three evaluators to come up with a judgment on the quality of 57 randomized controlled trials assigning a score to each trial using the Jadad scale. The quality was evaluated according to the following dimensions: adopted design, randomization unit, type of primary endpoint. With respect to each of the above described features, the agreement between the three evaluators has been calculated using Cohen's Kappa statistic and Gwet's AC1 statistic and, finally, the values have been compared with the observed agreement. RESULTS: The values of the Cohen's Kappa statistic would lead to believe that the agreement levels for the variables Unit, Design and Primary Endpoints are totally unsatisfactory. The AC1 statistic, on the contrary, shows plausible values which are in line with the respective values of the observed concordance. CONCLUSION: We conclude that it would always be appropriate to adopt the AC1 statistic, thus bypassing any risk of incurring the paradox and drawing wrong conclusions about the results of agreement analysis.

Long term interaction between dietary patterns and disease incidence: evidence from serbia

The objective of this study was to evaluate the relationship between dietary pattern and incidence of nutrition-related non-communicable diseases in Serbia, a country which has experienced a significant shift in nutrition and lifestyle habits, guided by its particular historical background and its rapid transition to liberal economy. Data was collected from annual reports published by the Statistical Office of the Republic of Serbia and the Institute of Public Health. It provides a focus on the timeframe of 1997-2014, in order to capture any changing pattern after the year 2000, in which the process of complete trade liberalization started.The results have shown a striking growing trend in both disease incidence on the one hand and processed food items such as processed meat, fruit juices, chocolate and biscuits and on the other hand. Granger causality test suggests that there exists causality that goes beyond spurious relationship between the disease of blood and blood-forming organs and immune system disorders and average per capita consumption of fruit and vegetables, poultry, processed meat, chocolates and biscuits and fruit juices. Also, we find evidence of long-term relationship between fish consumption and endocrine, metabolic and digestive diseases(AU)

El objetivo de este estudio fue evaluar la relación entre los patrones de dieta y la incidencia de las enfermedades no transmisibles relacionadas con la nutrición en Serbia, un país que ha experimentado un cambio significativo en los hábitos de nutrición y estilo de vida, guiado por sus antecedentes históricos particulares y su rápida transición hacia una economía liberal. Se recogieron datos de los informes anuales publicados por la Oficina de Estadística de la República de Serbia y el Instituto de Salud Pública. Se hizo foco en el período de 1997 a 2014, con el fin de poder detectar cualquier cambio en los patrones a partir del año 2000, cuando comenzó el proceso de liberalización total del comercio. Los resultados han mostrado llamativamente una tendencia creciente tanto en la incidencia de enfermedades como en la proliferación de alimentos procesados, tales como carne procesada, jugos de frutas, chocolate y galletas. La prueba de causalidad de Granger sugiere que existe una relación de causalidad que va más allá de la relación espuria entre las enfermedades hematológicas, las afecciones de los órganos hematopoyéticos y del sistema inmunológico y el consumo promedio per cápita de frutas y hortalizas, productos avícolas, carne procesada, chocolates, galletas y jugos de frutas. Parece evidente también la existencia de una relación a largo plazo entre la aparición de enfermedades endocrinas, metabólicas y digestivas y el consumo de pescado(AU)

The influence of cationic impurities in silica on its crystallization and point of zero charge.

The influence of the heat treatment on the crystal structure change of five (two laboratory prepared and three commercial) silica powders were investigated. Silicas were heat treated in the temperature range from 150 to 1300 degrees C in air. Also, the influence of the washing procedure with 0.01 mol/L HCl in order to desorb cations present as impurities in silica samples, was studied. The change of the amorphous into the crystal structure (alpha-cristobalite) takes place in the range 1050-1300 degrees C, depending on the chemical purity of silica samples. Points of zero charge, pHpzc, of the same silica samples, ranging from 3.8 to 7.1, were also determined by batch equilibration method. It is shown that the desorption of cations from silica samples, i.e., increase in their purity, leads to a shift in pHpzc toward lower values.