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1.
Clin Neurol Neurosurg ; 112(10): 844-8, 2010 Dec.
Article in English | MEDLINE | ID: mdl-20667421

ABSTRACT

OBJECTIVE: The prognostic value of electrophysiology and its significance in the prediction facial function outcome in facial palsy patients remains unclear because of the different methodologies used in previous studies. We aimed to establish the prognostic value of electrophysiological testing in a group of patients with facial palsy. METHODS: We prospectively analyzed facial nerve electrophysiology results and compared them with the House-Brackmann scale in 65 patients. The treatment consisted of a standard corticosteroid plus antiviral regimen. Clinical evaluation comprised the House-Brackmann grading system and electrophysiological tests (nerve excitability, nerve conduction study (NCS), needle electromyography (EMG), and blink reflex) conducted on the 5th, 20th, and 90th days after paralysis onset. RESULTS: In predicting the prognosis, the nerve excitability test in the acute phase, NCS in the subacute phase, blink reflex in the acute and subacute phases and needle EMG in the subacute phase provided statistically significant results. CONCLUSION: Prognosis can be determined, and excessive tests can be eliminated with proper timing and electrophysiological testing. SIGNIFICANCE: In determining the prognosis of facial paralysis, the nerve excitability test should be used in the acute phase, and NCS and needle EMG should be used in the subacute phase. Blink reflex studies are helpful in both the acute and subacute phases.


Subject(s)
Facial Paralysis/physiopathology , Acyclovir/analogs & derivatives , Acyclovir/therapeutic use , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Inflammatory Agents/therapeutic use , Antiviral Agents/therapeutic use , Blinking/physiology , Electrodiagnosis , Electromyography , Electrophysiological Phenomena , Facial Paralysis/drug therapy , Female , Humans , Male , Middle Aged , Neural Conduction/physiology , Neurologic Examination , Predictive Value of Tests , Prednisolone/therapeutic use , Prognosis , Treatment Outcome , Valacyclovir , Valine/analogs & derivatives , Valine/therapeutic use , Young Adult
2.
Neurologist ; 16(2): 109-12, 2010 Mar.
Article in English | MEDLINE | ID: mdl-20220445

ABSTRACT

OBJECTIVES: Hot water epilepsy (HWE) or bathing epilepsy is one of the reflex epilepsies induced by hot water pouring over the head, face, neck, or trunk during bathing. The aim of this study was to demonstrate the clinical and electroencephalographic features and the management alternatives of the patients with HWE. METHODS: The age of seizure onset, duration of seizure, family history, interictal and postictal electroencephalography findings, triggering temperature of water, type of seizure, medication, and follow-up results were evaluated for each patient. RESULTS: The mean age at seizure onset was 10.5 years. The mean duration of seizures was 10 years. Interictal EEG recordings showed focal abnormalities in 4 patients and generalized abnormalities in 3 patients. Only one patient had normal interictal EEG findings. Among the 8 patients with HWE, 6 had seizures only during hot bathing, whereas 2 had additional seizures. Seven patients had generalized tonic-clonic seizures and 1 patient had complex partial seizure during their hot bathings. The mean triggering temperature of water was calculated as 41.4 degrees C. The mean duration of follow-up period was 23 months. Five patients became seizure-free during the follow-up period and seizures persisted in 3 patients. Antiepileptic drugs were given (800 mg/d carbamazepine for 2 patients and 600 mg/d phenytoin for 1 patient) to these 3 patients and they also became seizure-free during the follow-up period. CONCLUSIONS: Hot water epilepsy is a benign reflex epilepsy. Lowering water temperature must be the first step for the treatment. If needed, antiepileptic drugs should be considered as an additive treatment.


Subject(s)
Epilepsy/drug therapy , Epilepsy/physiopathology , Hot Temperature , Seizures/drug therapy , Seizures/physiopathology , Water , Adolescent , Age of Onset , Anticonvulsants/therapeutic use , Brain/physiopathology , Child , Child, Preschool , Electroencephalography , Epilepsy/etiology , Epilepsy, Complex Partial/drug therapy , Epilepsy, Complex Partial/etiology , Epilepsy, Complex Partial/physiopathology , Family , Follow-Up Studies , Humans , Male , Seizures/etiology , Temperature , Time Factors
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