Quantifying the impact of anthropogenic emissions and aquatic environmental impacts on sedimentary mercury variations in a typical urban river.

In urban and industrial regions, sedimentary mercury (Hg) serves as the crucial indicator for Hg pollution, posing potential risks to ecology and human health. The physicochemical processes of Hg in aquatic environments are influenced by various factors such as anthropogenic emissions and aquatic environmental impacts, making it challenging to quantify the drivers of total mercury (THg) variations. Here, we analyzed the spatiotemporal variations, quantified driving factors, and assessed accumulation risks of sedimentary THg from the mainstream of a typical urban river (Haihe River). THg in the urban region (37-3237 ng g-1) was significantly higher (t-test, p < 0.01) than in suburban (71-2317 ng g-1) and developing regions (156-916 ng g-1). The sedimentary THg in suburban and developing regions increased from 2003 to 2018, indicating the elevated atmospheric deposition of Hg. Together with the temperature, grain size of sediments, total organic carbon (TOC), the pH and salinity of water, 40 components of parent and substituted polycyclic aromatic hydrocarbons (PAHs) were first introduced to quantify the driver of sedimentary THg based on generalized additive model. Results showed that anthropogenic emissions, including three PAHs components (31%) and TOC (63%), accounted for 94% of sedimentary THg variations. The aquatic environmental impacts accounted for 5% of sedimentary THg variations. The geo-accumulation index of THg indicated moderate to heavy accumulation in the urban region. This study demonstrates that homologous pollutants such as PAHs can be used to trace sources and variations of Hg pollution, supporting their co-regulation as international conventions regulate pollutants.

Pollution characteristics and affecting factors of phthalate esters in agricultural soils in mainland China.

Phthalate esters (PAEs), the most commonly produced and used plasticizers, are widely used in plastic products and agroecosystems, posing risks to agricultural products and human health. However, current research on PAE pollution characteristics in agricultural soils in China is not comprehensive; affecting factors and relationships with microplastics and plasticizer organophosphate esters have not been sufficiently considered. In this study, farmland soil samples were collected with field questionnaires on a national scale across mainland China. The results showed that the detection rate of PAEs was 100% and the Σ16PAEs concentrations were 23.5 - 903 µg/kg. The level of PAEs was highest in the greenhouse, and significantly higher than that in mulched farmland (p < 0.05). The PAE concentration in northwestern China was the lowest among different physical geographic zones. PAEs in farmlands posed a low cancer risk to Chinese people. PAE pollution in farmlands was significantly (p < 0.05) affected by agronomic measures (such as disposal method), environmental factors, and socioeconomic factors. Overall, PAEs were significantly and positively correlated (p < 0.05) with organophosphate esters but not with microplastics. This study aims to provide scientific data for relevant prevention and control policies, as well as actionable recommendations for pollution reduction.

[Latest Findings on Stimuli-Responsive Hydrogel Wound Dressings Applied in Diabetic Chronic Wound Repair].

Diabetic chronic wounds entail enormous psychological and economic burdens on diabetic patients. Traditional types of wound dressings lack diversity in their functions and do not have sufficient adaptability to the wound environment, which makes it difficult to meet the complicated needs arising during the healing process when they are used. Stimuli-responsive hydrogels respond specifically to the special environment of the wound area, for example, temperature, pH, glucose, etc., and achieve on-demand release by loading active substances, which effectively promotes diabetic wound healing. Herein, based on the research progress in stimulus-responsive wound dressings in recent years and the relevant work of our research team, we summarized and discussed hydrogel wound dressings responsive to temperature, pH, glucose, reactive oxygen species, enzymes, and multiple stimuli. Based on the special physiological environment of diabetic wounds, hydrogels with single or multiple stimuli-responsive properties can be designed so that they can release drugs on demand and improve the microenvironment of the wound, thus meeting the specific needs of different stages of wound healing. Although stimuli-responsive hydrogels currently show excellent therapeutic potential, there is still room for further development-cells or cytokines loaded in wound dressings usually act only at specific healing stages and the timing needs to be precisely controlled in order to avoid counterproductive effects on wound healing. In addition, the construction of sensor-therapeutic integrated devices for real-time monitoring of wound biochemical indicators so that drugs are release on demand and with precision to promote wound healing is also one of the topics that deserve more attention from researchers.

Status, characteristics, and ecological risks of microplastics in farmland surface soils cultivated with different crops across mainland China.

Microplastics (MPs) in agricultural soils could affect the safety of food crops. However, most relevant studies have paid scant attention to the crop fields and focused more on MPs in farmlands with or without film mulching in different regions. To detect MPs, we investigated farmland soils with >30 typical crop species from 109 cities in 31 administrative districts across mainland China. The relative contributions of different MP sources in different farmlands were estimated in detail based on a questionnaire survey, and we also assessed the ecological risks of MPs. Our results indicated the order of MP abundances in farmlands with different crop types, namely fruit fields > vegetable fields > mixed crop fields > food crop fields > cash crop fields. For the detailed sub-types, the highest MP abundance was detected in grape fields, which was significantly higher than that in solanaceous & cucurbitaceous vegetable fields (ranked second, p < 0.05), whereas the MP abundance was lowest in cotton and maize fields. The total contributions of three potential sources, namely livestock and poultry manure, irrigation water, and atmospheric deposition to MPs, varied depending on the crop types in the farmlands. Owing to exposure to MPs, the potential ecological risks to agroecosystems across mainland China were not negligible, particularly in fruit fields. The results of the current study could provide basic data and background information for future ecotoxicological studies and relevant regulatory strategies.

Adhesive Ion-Conducting Hydrogel Strain Sensor with High Sensitivity, Long-Term Stability, and Extreme Temperature Tolerance.

Ion-conducting hydrogels with excellent flexibility and ductility have great potential in human movements monitoring. However, some obstacles, including a small detection range, low sensitivity, low electrical conductivity, and poor stability under extreme conditions, impede their use as sensors. Herein, an ion-conducting hydrogel comprising acrylamide (AM), lauryl methacrylate (LMA), 2-acrylamido-2-methylpropanesulfonic acid (AMPS), and a water/glycerol binary solvent (named the AM-LMA-AMPS-LiCl (water/glycerol) hydrogel) is designed, which exhibits an enlarged detection range of 0%-1823% and improved transparency. Notably, the ion channel constructed using AMPS and LiCl significantly improves the sensitivity (gauge factor = 22.15 ± 2.86) of the hydrogel. The water/glycerol binary solvent endows the hydrogel with electrical and mechanical stability under extreme conditions (70 and -80 °C). Furthermore, the AM-LMA-AMPS-LiCl (water/glycerol) hydrogel exhibits antifatigue properties for 10 cycles (0%-1000%) because of noncovalent interactions such as hydrophobic interactions and hydrogen bonding. The hydrogel can be used to monitor human movements such as joint bending and perceive subtle discrepancies such as different joint bending speeds and angles, showing its great potential application in human movement monitoring, electronic skin, and wearable devices.

Spatial Distributions, Compositional Profiles, Potential Sources, and Intfluencing Factors of Microplastics in Soils from Different Agricultural Farmlands in China: A National Perspective.

More attention has been paid to ubiquitous microplastics (MPs). As a major food producer, the situation of MPs in China's farmland is of even greater concern. Spatial distributions, characteristics, and compositions of MPs in five types of agricultural lands with representative crops were investigated by collecting 477 soil samples from 109 cities in 31 administrative regions of mainland China. To better control MPs in farmland, nearly 400 field questionnaires were obtained, and meteorological conditions, soil properties, and other statistics were collected to quantify potential sources and determine influencing factors. The average abundances of MPs was 2462 ± 3767 items/kg in the agricultural soils, and MP abundance in the greenhouses, farmlands with film mulching, and blank farmlands from four integrated physical geographic regions were determined. The contributions of agricultural films, livestock and poultry manures, irrigation water, and air deposition to MPs in farmlands have been calculated. Influencing factors, such as recovery method, plowing frequency, meteorological conditions, and part of soil properties, were significantly correlated with the abundances of MPs in the agricultural soils (p < 0.05), while mulching age mainly affected MPs in the greenhouses (p < 0.05). This study provides basic scientific data for decision-making and further analysis.

The efficacy of soap against schistosome cercariae: A systematic review.

BACKGROUND: Schistosomiasis is a parasitic disease that is endemic in 78 countries and affects almost 240 million people worldwide. It has been acknowledged that an integrated approach that goes beyond drug treatment is needed to achieve control and eventual elimination of the disease. Improving hygiene has been encouraged by World Health Organisation, and one aspect of good hygiene is using soap during water-contact activities, such as bathing and doing laundry. This hygiene practice might directly reduce the skin exposure to cercariae at transmission sites. A systematic review was carried out to investigate the efficacy of soap against schistosome cercariae and to identify the knowledge gaps surrounding this topic. METHODOLOGY: Six online databases were searched between 5th and 8th July of 2021. Records returned from these databases were screened to remove duplicates, and the remaining records were classified by reading titles, abstracts, and full texts to identify the included studies. The results were categorised into two groups based on two different protective mechanisms of soap (namely, damage to cercariae and protection of skin). CONCLUSIONS: Limited research has been conducted on the efficacy of soap against schistosome cercariae and only 11 studies met the criteria to be included in this review. The review demonstrates that soap has the potential of protecting people against schistosome cercariae and there are two protective aspects: (1) soap affects cercariae adversely; (2) soap on the skin prevents cercariae from penetrating the skin, developing into adult worms and producing eggs. Both aspects of protection were influenced by many factors, but the differences in the reported experimental conditions, such as the cercarial endpoint measurement used and the cercaria numbers used per water sample, lead to low comparability between the previous studies. This review indicates that more evidence is needed to inform hygiene advice for people living in schistosomiasis endemic areas.

Spatial distribution and risk assessment of 11 organophosphate flame retardants in soils from different regions of agricultural farmlands in mainland China.

The occurrence and distribution of organophosphate flame retardants (OPFRs) in nationwide farmland soils of mainland China are rarely measured. The current study was the first to collect 325 farmland soil samples from 109 cities throughout mainland China. Ten organophosphate esters (OPEs), including alkyl-OPEs, Cl-OPEs, and aryl-OPEs, together with an organophosphate intermediates (TPPO), were determined. The results indicated that ΣOPFRs ranged from 2.41 ng/g to 35.8 ng/g dry weight (dw), and ΣOPFRs in northeastern and southern China were significantly (p < 0.01) higher than those in northwestern and central China. Alkyl-OPEs and Cl-OPEs served as the main components of OPEs, and the novel aryl-OPEs showed the highest detection frequency (> 92 %). Principal component analysis (PCA) was employed to identify the different sources of OPEs, in which atmospheric deposition, irrigation, or direct release of plastic mulch acted as the main input routes in farmland soils. The potential risks of OPFRs were assessed through soil ingestion exposure and ecotoxicological impacts. Our results showed that direct exposure to farmland soils had no high risks to the human body and ecological environments. This study provides new evidence for further understanding the spatial distributions and contamination status of OPFRs in farmland soils throughout mainland China.

Insights into the horizontal and vertical profiles of microplastics in a river emptying into the sea affected by intensive anthropogenic activities in Northern China.

Studies focused only on surface water may underestimate microplastic abundance in aquatic environments. This was the first survey to investigate the vertical (surface, intermediate, and bottom waters) distribution and composition of microplastics (MPs) in the water columns and surface sediments collected from an urban seagoing river in northern China. Microplastic abundance in the water columns ranged from 5.6 to 31.4 items∙L-1 and from 2141 to 10,035 items∙kg-1 dry weight (dw) in the surface sediments. Polyethylene dominated throughout the water columns to the surface sediments, in which low- and high-density polyethylene (LDPE and HDPE) were dominant in the water columns and surface sediments, respectively. The dominant shape of MPs was fibers/lines in both the water column and the surface sediment samples. Different from the estimations, the average abundance of MPs in the surface and intermediate waters was significantly lower (p < 0.01) than that in the bottom water, which may be due to the resuspension of small-sized MPs in the bottom water. As the MPs size increased, their vertical distributions in the water columns were more affected by the water depth. The results showed that MPs were detained in the water columns of river system, and the high concentrations of MPs in the bottom water could not be neglected.

Distribution characteristics of microplastics in agricultural soils from the largest vegetable production base in China.

The study area is situated in Shouguang City, Shandong Province, as the largest greenhouse vegetable production base in Northern China. Samples of facility agricultural soil, open-field agricultural soil, and agricultural plastic mulch film were collected to investigate the distribution characteristics, influencing factors, and discharging sources of microplastics (MPs). Microplastic abundance of three soil layers at all sampling sites ranged from 310 to 5698 items/kg, with an average value of 1444 ± 986 items/kg. The main size category of MPs was less than 0.5 mm, and the contribution of MPs with sizes <0.5 mm in the 10-25 cm layer of facility agricultural soils was significantly higher (p < 0.05) than that in the 0-5 cm soil layer, which indicated that small MPs tended to migrate to deeper soil layers. The prevailing shapes of MPs were fragment and film, while polypropylene, ethylene-propylene copolymer, and polyethylene dominated among chemical compositions. The fractions of silty and sandy particles were correlated with the abundance of MPs, and the microplastic abundance in sandy loam was significantly higher (p < 0.05) than that in silty loam or loam based on the international classification standard. Thus, the soil texture may affect the distribution of MPs in local agricultural soils. In addition, the planting age of facility agricultural soil was related to microplastic abundance, while there was no significant difference in the microplastic abundances of facility agricultural soils under different irrigation methods. CAPSULE: The microplastic abundance in sandy loam surpassed that in silty loam or loam, small size (<0.5 mm) MPs tended to migrate to deeper soil layers, and planting age affected microplastic abundance in facility agricultural soils.

Effects of anthropogenic discharge and hydraulic deposition on the distribution and accumulation of microplastics in surface sediments of a typical seagoing river: The Haihe River.

Microplastics pollution in river systems has generated great concern; however, few studies have focused on the contributions of multiple influencing factors to microplastics in river systems. In the current study, we utilized data on microplastics in surface sediments from the Haihe River, a seagoing river in northern China to establish a generalized additive model (GAM) for quantifying the effects of multiple factors on the distribution of microplastics. A high abundance of microplastics (4980 ± 2462 items∙kg-1 dry weight) was found. Small particles (< 1000 µm) accounted for a dominant proportion (44.8-61.0%). Polyethylene (PE) was the chief component with an averaged fraction of 49.3%, in which low- and high-density polyethylene contributed 90.7% and 9.3% of the PE, respectively. Microplastics abundance was positively correlated with sediment TOC and the silt fraction (p < 0.05) but negatively correlated with the sand fraction (p < 0.05). The GAM could explain approximate 60% of the total microplastics abundance, and dam (28.5%), sediment TOC (22.9%), and sewage effluent (17.6%) were the main contributors to total variations in microplastics abundance. Local sewage effluent acted as an important point source of microplastics discharge, and the dam on the river greatly affected the deposition and accumulation of microplastics.

Distribution, partitioning behavior, and ecological risk assessment of phthalate esters in sediment particle-pore water systems from the main stream of the Haihe River, Northern China.

The distribution, partitioning behavior and risk assessment of phthalate esters (PAEs) in the surface sediment-pore water system of the Haihe River were investigated. The total cumulative concentrations of 21 PAE species (Σ21PAEs) in the surface sediment ranged from 45.9 to 1474.1 ng·g-1 dry weight (dw) and were from 17.9 to 2628.8 ng·mL-1 in the pore water. Di (2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), and diisobutyl phthalate (DIBP) were the dominant components, and their sum accounted, on average, for 88.4% and 72.0% of Σ21PAEs in the surface sediment and pore water, respectively. The spatial distributions of Σ21PAEs in the surface sediment and pore water indicated that large amounts of the consumed products contained plasticizers in the urban and nearshore areas and increased the discharge of PAEs into the Haihe River. The river dam also affected PAEs distributions. The organic carbon normalized partitioning coefficient (logKOC) followed a sequence as dry season (2.47 ± 0.35 mL·g-1) > wet season (2.02 ± 0.45 mL·g-1) > normal season (1.98 ± 0.42 mL·g-1). The risk quotient (RQ) method was employed to assess the potential ecological risk from specific species. High ecological risks of DEHP to the sensitive algae, crustacean, and fish species along with high ecological risks of DIBP to sensitive fish species were found in the surface sediment and pore water for all sampling seasons. In addition, DBP in the surface sediment and pore water exhibited moderate and high ecological risks to sensitive aquatic species. The highest RQ values for PAEs were found in the surface sediment and pore water in suburban and urban areas, respectively, and indicated that anthropogenic activities may cause severe river pollution and high risk to the local aquatic ecosystem. CAPSULE: High levels and ecological risks from PAEs were found in the urban river, and the partitioning behaviors of PAEs between the surface sediment and pore water were not significantly affected by their hydrophobicity, especially for species with low KOW.

Occurrence and characteristics of microplastics in the Haihe River: An investigation of a seagoing river flowing through a megacity in northern China.

Freshwater systems serve as important sources and transportation routes for marine microplastic pollution, and inadequate attention has been paid to this situation. Data on microplastic pollution of typical seagoing rivers in northern China are lacking. In the current study, we investigated the distribution and characteristics of microplastics in the main stream of the Haihe River, which flows through a metropolis with a high population density and level of industrialization and then flows into the Bohai Sea. The microplastic samples were collected by manta trawls with pore sizes of 333 µm, and the microplastic concentrations ranged from 0.69 to 74.95 items/m3. Fibers dominated in the surface water of the Haihe River; their shapes that were categorized as fibers, film, foam, fragments, and spheres, and contributed 17.4-86.7% of the total microplastics studied. The size distribution of the microplastics was concentrated in a range of 100-1000 µm, with 54.7% of the total sizes corresponding to the 333-µm trawl. Micro-Fourier transform infrared (µ-FT-IR) spectra showed that the main components were polyethylene, poly(ethylene-propylene) copolymer, and polypropylene. Scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) measurements revealed scratches, micropores, and cracks on the surfaces of the microplastics due to mechanical friction, chemical oxidation and degradation processes. The results of this study confirmed the high abundance and high diversity of microplastics in an urban river and indicated appreciable impacts from point-source inputs on the microplastic pollution, such as effluents from wastewater treatment plants (WWTPs).

Distribution characteristics of and personal exposure with polycyclic aromatic hydrocarbons and particulate matter in indoor and outdoor air of rural households in Northern China.

Gaseous and particulate polycyclic aromatic hydrocarbons (PAHs) and size-segregated particulate matter (PM) in indoor air and outdoor air, along with personal exposure, were monitored in rural households of Northern China. The daily average concentrations of 28 species were 1310 ±â€¯811, 738 ±â€¯321, 465 ±â€¯247, and 655 ±â€¯250 ng/m3 in kitchen air, bedroom air, and outdoor air, and for personal exposure, respectively. PAHs tended to occur in the particulate phase with increasing molecular weight. Absorption by particulate organic carbon was dominant in the gas-particle partitioning process. The daily averaged concentrations of PM2.5 and PM1.0 were 104 ±â€¯39.5 and 88.4 ±â€¯39.3 µg/m3 in kitchen air, 79.0 ±â€¯63.2 and 65.7 ±â€¯57.5 µg/m3 in bedroom air, 52.9 ±â€¯16.5 and 41.5 ±â€¯12.5 µg/m3 in outdoor air, and 71.7 ±â€¯30.8 and 61.5 ±â€¯28.4 µg/m3 for personal exposure, respectively. The non-priority components contributed 5.5 ±â€¯2.8% to the total PAHs, while their fraction of carcinogenic risk reached 85.6 ±â€¯6.9%. The mean cancer risk posed to rural residents via inhalation exposure to PAHs exceeded the current acceptable threshold of 1.0 × 10-6 and the national average estimated in China. The personal exposure levels of PAHs and PM in households using clean energy were lower than those in households using traditional biomass by 30.0%, 29.4%, and 38.5% for PAH28, PM2.5, and PM1.0, respectively. However, the cancer risk of personal inhalation exposure to PAH28 from using liquid petroleum gas (LPG) was higher than that from using firewood, implying the adoption of LPG may not effectively reduce the cancer risk despite the decreasing exposure levels of PAH28 and PM with respect to the use of firewood. Cooking individuals suffered higher exposure levels of PAH28 and PM1.0 compared with non-cooking individuals, and the cancer risk of personal inhalation exposure to PAH28 for cooking individuals was 1.7 times that for non-cooking individuals. Cooking was a critical factor that affected the personal exposure levels of the local male and female residents.

Characteristics and human inhalation exposure of ionic per- and polyfluoroalkyl substances (PFASs) in PM10 of cities around the Bohai Sea: Diurnal variation and effects of heating activity.

Atmospheric PM10 (particulate matter with aerodynamic diameter <10 µm) samples were collected in the cities along the Bohai Sea Rim during heating and non-heating periods, and ionic per- and polyfluoroalkyl species (PFASs) in the PM10 were measured. The total concentration of ionic PFASs ranged from 21.8 to 87.0 pg/m3, and the mean concentration of ionic PFASs during the day (42.6 pg/m3) was slightly higher than that at night (35.1 pg/m3). Generally, diurnal variations in the levels of ionic PFASs were consistent with those in the PM10 concentrations. Perfluorooctanoic acid (PFOA, 23.5-33.7%), perfluoropentanoic acid (PFPeA, 28.3-39.9%) and perfluorobutyric acid (PFBA, 17.1-20.1%) accounted for the dominant compositional contributions. Significant positive correlations (p < 0.05) between the main components of PFASs and O3 implied that oxidative degradation (O3 served as the main oxidant) in the period of non-heating may affect the short-chain PFASs. The clustering analysis of a 72-h backward trajectory indicated that cross-provincial transport contributed to ionic PFASs at the sampling sites. Compared with ingestion via daily diet, the inhalation of PM10 exhibited an insignificant contribution to the estimated average daily intakes (ADIs) of PFASs by different age groups. In addition, the calculated hazard ratios (HRs) for the non-cancer respiratory risk, based on the air concentrations of PFOA and perfluorooctane sulfonate (PFOS), also manifested lower non-cancer risk through inhalation exposure. CAPSULE: The effects of heating and non-heating activity and diurnal variation on the concentrations of PFASs, dominated by PFOA, PFPeA, and PFBA in PM10, were determined, and atmospheric trans-provincial input served as an important source.