A functional regression analysis of vessel source level measurements from the Enhancing Cetacean Habitat and Observation (ECHO) database.

Measurements of the source levels of 9880 passes of 3188 different large commercial ships from the Enhancing Cetacean Habitat and Observation (ECHO) program database were used to investigate the dependencies of vessel underwater noise emissions on several vessel design parameters and operating conditions. Trends in the dataset were analyzed using functional regression analysis, which is an extension of standard regression analysis and represents a response variable (decidecade band source level) as a continuous function of a predictor variable (frequency). The statistical model was applied to source level data for six vessel categories: cruise ships, container ships, bulk carriers, tankers, tugs, and vehicle carriers. Depending on the frequency band and category, the functional regression model explained approximately 25%-50% of the variance in the ECHO dataset. The two main operational parameters, speed through water and actual draft, were the predictors most strongly correlated with source levels in all of the vessel categories. Vessel size (represented via length overall) was the design parameter with the strongest correlation to underwater radiated noise for three categories of vessels (bulkers, containers, and tankers). Other design parameters that were investigated (engine revolutions per minute, engine power, design speed, and vessel age) had weaker but nonetheless significant correlations with source levels.

Population Dynamics of Underdominance Gene Drive Systems in Continuous Space.

Underdominance systems can quickly spread through a population, but only when introduced in considerable numbers. This promises a gene drive mechanism that is less invasive than homing drives, potentially enabling new approaches in the fight against vector-borne diseases. If regional confinement can indeed be achieved, the decision-making process for a release would likely be much simpler compared to other, more invasive types of drives. The capacity of underdominance gene drive systems to spread in a target population without invading other populations is typically assessed via network models of panmictic demes linked by migration. However, it remains less clear how such systems would behave in more realistic population models where organisms move over a continuous landscape. Here, we use individual-based simulations to study the dynamics of several proposed underdominance systems in continuous-space. We find that all these systems can fail to persist in such environments, even after an initially successful establishment in the release area, confirming previous theoretical results from diffusion theory. At the same time, we find that a two-locus two-toxin-antidote system can invade connected demes through a narrow migration corridor. This suggests that the parameter space where underdominance systems can establish and persist in a release area while at the same time remaining confined to that area could be quite limited, depending on how a population is spatially structured. Overall, these results indicate that realistic spatial context must be considered when assessing strategies for the deployment of underdominance drives.

Distribution characteristics of meridian sinew (jingjin) syndrome in 313 cases of whiplash-associated disorders.

OBJECTIVE: To investigate and analyze the characteristics of Meridian Sinew (Jingjin) syndrome in patients with whiplash-associated disorders (WAD). METHODS: From August 2010 to September 2011, 313 WAD cases from New York and California states were collected. The survey mostly collects the information of "Sinew Knotted Points" and symptoms of four types of Meridian Sinew differentiation-Taiyang, Shaoyin, Shaoyang and Yangming. RESULTS: Among the cases which are on the average of medium injury level, the higher frequency of "Sinew Knotted Points" tenderness were found on Jianwaishu (SI 14), Jianzhongshu (SI 15), Tianchuang (SI 16), C3-6 Spinous Process, Dazhui (GV 14), Fengchi (GB 20), Tianliao (SJ 15) and Tianding (LI 17). The most commonly presented symptoms were widespread spasm and tenderness in the neck (Taiyang), difficulty in lateral flexion (Shaoyang), problems of extension and flexion (Taiyang), and stiffness and pain during neck movement (Yangming). Among the cases, 237 cases (75.72%) were related to Taiyang Meridian Sinew syndrome, 82 cases (26.20%) to Shaoyin syndrome and 175 (55.91%) and 176 (56.23%) cases to Shaoyang and Yangming syndrome respectively. The most of cases presented in a combination format. The syndrome distribution under Grade I, II and III reflected that more combination of the Meridian Sinew syndromes in the whiplash injury patients which is resulted from more severity of injury. CONCLUSION: It is practical to identify the location of abnormality through Meridian Sinew differentiation, considering both "Sinew Knotted Points" tenderness and corresponding symptoms, for the local neck symptoms of WAD.