ABSTRACT
BACKGROUND: Between 2002 and 2008, China's National Tuberculosis Control Programme created the Health X Project, financed in part by a World Bank loan, with additional funding from the UK Department for International Development. OBJECTIVES: To assess the cost-effectiveness of the Project and its impact from a financial point of view on tuberculosis (TB) control in China. METHODS: A decision-analytic model was used to evaluate the cost-effectiveness of the Project. Sensitivity analysis was used to assess the impact of different scenarios and assumptions on results. The primary outcome of the study was cost per disability-adjusted life-year (DALY) saved and incremental DALYs saved. RESULTS: In comparison with alternative scenario 1, the Project detected 1.6 million additional cases, 44 000 deaths were prevented and a total of 18.4 million DALYs saved. The Project strategies cost approximately Chinese yuan (CNY) 953 per DALY saved (vs. CNY1140 in the control areas), and saved an estimated CNY17.5 billion in comparison with the unchanged alternative scenario (scenario 1) or CNY10.8 billion with the control scenario (scenario 2). CONCLUSION: The Project strategies were affordable and of comparable cost-effectiveness to those of other developing countries. The results also provide strong support for the existing policy of scaling up DOTS in China.
Subject(s)
Antitubercular Agents/administration & dosage , National Health Programs/organization & administration , Tuberculosis/prevention & control , Antitubercular Agents/economics , China , Cost-Benefit Analysis , Decision Support Techniques , Developing Countries , Directly Observed Therapy , Humans , National Health Programs/economics , Program Development , Program Evaluation , Quality-Adjusted Life Years , Tuberculosis/economics , United Nations/economicsSubject(s)
Anti-Bacterial Agents/pharmacology , Drug Resistance, Multiple, Bacterial , Pneumococcal Infections/microbiology , Respiratory Tract Infections/microbiology , Streptococcus pneumoniae/drug effects , Child, Preschool , China/epidemiology , Cross-Sectional Studies , Female , Hospitalization , Humans , Male , Microbial Sensitivity Tests , Pneumococcal Infections/drug therapy , Pneumococcal Infections/epidemiology , Respiratory Tract Infections/drug therapy , Serotyping , Streptococcus pneumoniae/classification , Streptococcus pneumoniae/isolation & purificationABSTRACT
We evaluated animal food intake and cooking methods in relation to endometrial cancer risk in a population-based case-control study in Shanghai, China. A validated food frequency questionnaire was used to collect the usual dietary habits of 1204 cases and 1212 controls aged 30-69 years between 1997 and 2003. Statistical analyses were based on an unconditional logistic regression model adjusting for potential confounders. High intake of meat and fish was associated with an increased risk of endometrial cancer, with adjusted odds ratios for the highest vs the lowest quartile groups being 1.7 (95% confidence interval: 1.3-2.2) and 2.4 (1.8-3.1), respectively. The elevated risk was observed for all types of meat and fish intake. Intake of eggs and milk was not related to risk. Cooking methods and doneness levels for meat and fish were not associated with risk, nor did they modify the association with meat and fish consumption. Our study suggests that animal food consumption may play an important role in the aetiology of endometrial cancer, but cooking methods have minimal influence on risk among Chinese women.
Subject(s)
Cooking/methods , Diet/adverse effects , Endometrial Neoplasms/etiology , Meat/adverse effects , Adult , Aged , Case-Control Studies , China , Female , Humans , Middle Aged , Risk FactorsABSTRACT
We report measurements of the oxygen-isotope effect (OIE) on the in-plane penetration depth lambda(ab)(0) in underdoped La2-xSrxCuO4 single crystals. A highly sensitive magnetic torque sensor with a resolution of Deltatau approximately 10(-12) N m was used for the magnetic measurements on microcrystals with a mass of approximately 10 &mgr;g. The OIE on lambda(-2)(ab)(0) is found to be -10(2)% for x = 0.080 and -8(1)% for x = 0.086. It arises mainly from the oxygen-mass dependence of the in-plane effective mass m(*)(ab). The present results suggest that lattice vibrations are important for the occurrence of high temperature superconductivity.