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Lik Sprava ; (1-2): 35-9, 2014.
Article in Ukrainian | MEDLINE | ID: mdl-24908957

ABSTRACT

Present article is devoted to the study of the clinic features of ischemic heart desease associated with acid peptic disease. It was shown the more evident increase of myocardial infarction risk in associated pathology patients. Such results have to be caused by the special risk factor. As such factor we desided to study the hyperhomosysteinemia. During research there were discovered that the lowest vitamin B12 serum level and the highest homocysteine serum level have been registrated in associated pathology (ischemic heart disease and acid peptic disease according to long-term proton pump inhibitor use) patients. It was shown evident correlation between that changes and dyslipidemia.


Subject(s)
Gastroesophageal Reflux/complications , Hyperhomocysteinemia/complications , Myocardial Ischemia/etiology , Peptic Ulcer/complications , Case-Control Studies , Cholesterol/blood , Gastroesophageal Reflux/blood , Gastroesophageal Reflux/drug therapy , Gastroesophageal Reflux/epidemiology , Homocysteine/blood , Humans , Hyperhomocysteinemia/blood , Hyperhomocysteinemia/epidemiology , Myocardial Ischemia/blood , Myocardial Ischemia/epidemiology , Peptic Ulcer/blood , Peptic Ulcer/drug therapy , Peptic Ulcer/epidemiology , Proton Pump Inhibitors/administration & dosage , Proton Pump Inhibitors/adverse effects , Proton Pump Inhibitors/therapeutic use , Risk Assessment , Risk Factors , Triglycerides/blood , Vitamin B 12/blood
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