ABSTRACT
This comprehensive clinical and laboratory study was designed to elucidate the antioxidant status of the volunteers before and after a course of general infrared irradiation. It was shown that the effect of high temperatures promotes the development of oxidative stress that is followed by the formation of adaptive reactions in the form of activation of antioxidant protection, enhancement of non-specific responses of the cells, increase of stability and restoration of structural homeostasis of erythrocyte membranes. The molecular mechanism of endothelium-independent vasodilation develops by the end of the treatment period; it may serve as the compensatory-adaptive reaction needed to maintain the adequate tone of the vascular wall and thereby to support the functioning of mechanisms supporting physical thermoregulation. The results of the study give evidence of the stimulatory influence of the described method on the adaptive and protective potential of the organism. It is concluded that the proposed scheme of physiotherapeutic treatment may be used for prophylactic purposes.
Subject(s)
Antioxidants/metabolism , Body Temperature Regulation/radiation effects , Erythrocyte Membrane/metabolism , Infrared Rays/therapeutic use , Steam Bath , Vasodilation/radiation effects , Adult , Endothelium, Vascular , Humans , MaleABSTRACT
Analysis of the lipid status and oxidation of serum of blood lipids by free radicals was performed in the study involving practically healthy volunteers who underwent a course of general air cryotherapy. It was ahown that oxidized and modified lipoproteins play an important role in the etiopathogenetic mechanisms underlying the development of vasoconstrictive reactions and heat production processes in response to the short-term exposure to extremely low temperatures.
Subject(s)
Cryotherapy/methods , Free Radicals/blood , Lipoproteins, LDL/blood , Adult , Cold Temperature , Humans , Male , Myocardial Contraction/physiology , Vasoconstriction/physiologyABSTRACT
The present clinical and laboratory study of the effects of general air cryogenic therapy on the characteristics of blood supply included practically healthy subjects. The study has demonstrate that dosed cold stress promotes adaptive capacities of the organism by modulating the oxygen-transporting function of the blood that in its turn stimulates the adaptive mechanisms and leads to decoupling tissue respiration. It is concluded that general air cryogenic therapy can be recommended as an instrument for the improvement of endurance of and resistibility to the action of hypoxemia in special groups of people under the low temperature conditions.