Common computations for metacognition and meta-metacognition.

Recent evidence shows that people have the meta-metacognitive ability to evaluate their metacognitive judgments of confidence. However, it is unclear whether meta-metacognitive judgments are made by a different system and rely on a separate set of computations compared to metacognitive judgments. To address this question, we asked participants (N = 36) to perform a perceptual decision-making task and provide (i) an object-level, Type-1 response about the identity of the stimulus; (ii) a metacognitive, Type-2 response (low/high) regarding their confidence in their Type-1 decision; and (iii) a meta-metacognitive, Type-3 response (low/high) regarding the quality of their Type-2 rating. We found strong evidence for the existence of Type-3, meta-metacognitive ability. In a separate condition, participants performed an identical task with only a Type-1 response followed by a Type-2 response given on a 4-point scale. We found that the two conditions produced equivalent results such that the combination of binary Type-2 and binary Type-3 responses acts similar to a 4-point Type-2 response. Critically, while Type-2 evaluations were subject to metacognitive noise, Type-3 judgments were made at no additional cost. These results suggest that it is unlikely that there is a distinction between Type-2 and Type-3 systems (metacognition and meta-metacognition) in perceptual decision-making and, instead, a single system can be flexibly adapted to produce both Type-2 and Type-3 evaluations recursively.

The timing of confidence computations in human prefrontal cortex.

Knowing when confidence computations take place is critical for building a mechanistic understanding of the neural and computational bases of metacognition. Yet, even though a substantial amount of research has focused on revealing the neural correlates and computations underlying human confidence judgments, very little is known about the timing of confidence computations. To understand when confidence is computed, we delivered single pulses of transcranial magnetic stimulation (TMS) at different times after stimulus presentation while subjects judged the orientation of a briefly presented visual stimulus and provided a confidence rating. TMS was delivered to either the right dorsolateral prefrontal cortex (DLPFC) in the experimental group or to vertex in the control group. We found that TMS to right DLPFC, but not to vertex, led to increased confidence in the absence of changes to accuracy or metacognitive efficiency. Critically, equivalent levels of confidence increase occurred for TMS delivered between 200 and 500 msec after stimulus presentation. These results suggest that confidence computations occur during a broad window that begins before the perceptual decision has been fully made and thus provide important constraints for theories of confidence generation.

The timing of confidence computations in human prefrontal cortex.

Knowing when confidence computations take place is critical for building mechanistic understanding of the neural and computational bases of metacognition. Yet, even though substantial amount of research has focused on revealing the neural correlates and computations underlying human confidence judgments, very little is known about the timing of confidence computations. Subjects judged the orientation of a briefly presented visual stimulus and provided a confidence rating regarding the accuracy of their decision. We delivered single pulses of transcranial magnetic stimulation (TMS) at different times after stimulus presentation. TMS was delivered to either dorsolateral prefrontal cortex (DLPFC) in the experimental group or to vertex in the control group. We found that TMS to DLPFC, but not to vertex, led to increased confidence in the absence of changes to accuracy or metacognitive ability. Critically, equivalent levels of confidence increase occurred for TMS delivered between 200 and 500 ms after stimulus presentation. These results suggest that confidence computations occur during a broad window that begins before the perceptual decision has been fully made and thus provide important constraints for theories of confidence generation.

[Applying Problem Behavior Theory to Investigate the Factors Affecting Tobacco Products Use by Students at Eight Universities in the Greater Taipei Area].

BACKGROUND: There is growing concern related to the recent rise in consumption of cigarettes, electronic cigarettes, and heated tobacco products. The government should pay more attention to the use of various tobacco products by university students. PURPOSE: Problem behavior theory was used in this study to explore the factors influencing the use of various tobacco products by university students in the Greater Taipei area. METHODS: In this cross-sectional study, convenience sampling was used to select eight institutions of higher education in the Greater Taipei area. Eight departments recognized by the Ministry of Education were then listed on a table for use in randomizing the selection of third- and fourth-year undergraduate students. A total of 115 participants filled out the questionnaires included in the self-administered online survey. Data analysis was conducted using logistic regression. RESULTS: The prevalence of tobacco-product use in the sample was 5.22%. Logistic regression analysis revealed having parents who smoked (adjusted odds ratio, AOR = 2.05), holding a positive attitude toward their parents' smoking (AOR = 4.23), having peers who smoked (AOR = 4.33), engaging in deviant behavior (AOR = 90.44), and having peers involved in deviant behavior (AOR = 103.99) to be associated with a higher likelihood of engaging in tobacco-product use. CONCLUSIONS / IMPLICATIONS FOR PRACTICE: Family, peers and delinquency significantly influence the usage behavior of university students with regard to tobacco products. The government should allocate greater resources for tobacco harm prevention education aimed at the parents of university students. In addition, integrating tobacco harm education into campus curricula, utilizing social media for online digital education, and providing students with counseling and support measures are strategies that may help reduce the tobacco-product use among this vulnerable population.

Atypical meta-memory evaluation strategy in schizophrenia patients.

BACKGROUND: Previous research has reported that patients with schizophrenia would regard false memories with higher confidence, and this meta-memory deficit was suggested as a neurocognitive marker of schizophrenia. However, how schizophrenia patients determine their memory decision confidence has received scant consideration. This study, therefore, aimed to characterize the extent to which meta-memory evaluation strategy differs between schizophrenia patients and healthy individuals, and how such difference contributes to the patients' meta-memory performance. METHODS: 27 schizophrenia patients and 28 matched healthy controls performed a temporal-order judgement (TOJ) task, in which they judged which movie frame occurred earlier in an encoded video, and then made retrospective confidence rating. Mixed effect regression models were performed to assess the between-group metacognitive evaluation strategy difference and its relationship to clinical symptoms. RESULTS: Compared to the control group, the patients' confidence ratings were correlated more with the recent confidence history and less with the TOJ-related evidence. The degree of dependence on recent history of confidence was negatively correlated with the severity of positive symptoms. Furthermore, by controlling for the first-order TOJ performance, we observed that the patients discriminated correct memory decisions from the incorrect ones as accurately as the controls. CONCLUSION: The present investigation revealed that schizophrenia patients tend to use more heuristics in making meta-memory evaluations, and such atypical strategy is related to their clinical symptoms. This study provides new insights into how schizophrenia patients perform meta-memory processes. Future research could consider examining such metacognitive deficits in light of other cognitive domains in psychosis.

Diffusion property and functional connectivity of superior longitudinal fasciculus underpin human metacognition.

Metacognition as the capacity of monitoring one's own cognition operates across domains. Here, we addressed whether metacognition in different cognitive domains rely on common or distinct neural substrates with combined diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI) techniques. After acquiring DTI and resting-state fMRI data, we asked participants to perform a temporal-order memory task and a perceptual discrimination task, followed by trial-specific confidence judgments. DTI analysis revealed that the structural integrity (indexed by fractional anisotropy) in the anterior portion of right superior longitudinal fasciculus (SLF) was associated with both perceptual and mnemonic metacognitive abilities. Using perturbed mnemonic metacognitive scores produced by inhibiting the precuneus using TMS, the mnemonic metacognition scores did not correlate with individuals' SLF structural integrity anymore, revealing the relevance of this tract in memory metacognition. To further verify the involvement of several cortical regions connected by SLF, we took the TMS-targeted precuneus region as a seed in a functional connectivity analysis and found the functional connectivity between precuneus and two SLF-connected regions (inferior parietal cortex and precentral gyrus) mediated mnemonic metacognition performance. These results illustrate the importance of SLF and a putative white-matter grey-matter circuitry that supports human metacognition.