Effects of different types of exercise intensity on improving health-related physical fitness in children and adolescents: a systematic review.

A substantial body of empirical evidence reveals that physical activity is associated with a wide range of positive physical and mental health outcomes. However, an absence of comprehensive syntheses is observed concerning the varying effects of different exercise intensities on the improvement of physical health among children and adolescents. The aim of this review is to systematically investigate the effects of different exercise intensities on the physical fitness of children and adolescents, to analyses the optimal exercise intensities for improving physical fitness, and to provide a relevant theoretical basis for optimizing school physical education curricula. A systematic search strategy was used in this study in four online databases (PubMed, Scopus, EBSCO and Web of Science). Intervention studies that met the inclusion criteria underwent a thorough screening process, and their methodological quality was assessed utilizing the PEDro scale. The selected literature was systematically analyzed and evaluated through induction, summary, analysis, and evaluation. These findings indicate that high-intensity exercise training exerts significant positive effects on body composition, cardiopulmonary function and muscle fitness in children and adolescents. Therefore, we suggest that schools should focus on high-intensity sports in their physical education curriculum, which can further improve the student's PHYSICAL FITNESS.

The effects of nicotine withdrawal on exercise-related physical ability and sports performance in nicotine addicts: a systematic review and meta-analysis.

BACKGROUND: Previous research has established that nicotine withdrawal can ameliorate cardiovascular and pulmonary function in smokers. Nevertheless, the impact on physical fitness and athletic performance remains under-investigated. OBJECTIVE: To evaluating the impacts of nicotine withdrawal on both exercise performance and exercise-associated physical capabilities in nicotine-dependent individuals. STUDY DESIGN: A comprehensive systematic review and meta-analysis. DATA SOURCES: The data was compiled from databases such as PubMed, Scopus, Web of Science, Cochrane Central, and EBSCO. STUDY SELECTION: The selection criteria required studies to elucidate the effects of nicotine withdrawal on exercise performance or exercise-related physical abilities. Moreover, the selected studies needed to provide discernible experimental results. DATA SYNTHESIS AND ANALYSIS: The random effects model was employed in data analysis, utilizing the standardized mean difference (SMD) and the 95% confidence intervals (95% CIs) to estimate participants' exercise performance and physical abilities, referencing the Mean ±SD during baseline and withdrawal states. RESULTS: Out of the selected studies, 10 trials were included, encompassing 13,538 participants aged 18 to 65 years. The findings suggest that nicotine withdrawal could potentially enhance sports performance (SMD = 0.45, 95% CI: 0.03 to 0.88; I^2 = 83%), particularly in terms of aerobic capacity. Short-term nicotine withdrawal (spanning 12 to 24 hours) might lead to a decline in participants' physical abilities in certain aspects like reaction time and sustained attention (SMD = -0.83, 95% CI: -1.91 to 0.25; I^2 = 79%), whereas long-term withdrawal (lasting 48 hours or more) demonstrated an opposing trend (SMD = 0.25, 95% CI: 0.12 to 0.39; I^2 = 81%). Overall, the results show that long-term nicotine withdrawal exhibited some positive impacts on sports performance and exercise-related physical ability, with the withdrawal duration being an indicator of subsequent physical performance. CONCLUSIONS: Mid- to long-term (≥3 months) nicotine withdrawal significantly improved the exercisers' exercise-related physical ability and sports performance. Conversely, short-term (≤24 hours) nicotine withdrawal considerably hampered exercisers' performance and physical cognition. It is suggested that exercises avoid abrupt nicotine cessation prior to competitions, as long-term nicotine withdrawal has been shown to significantly enhance exercise-related physiological capacities and athletic performance. By referring to existing literatures we also found that athletes with existing nicotine addiction may could consume nicotine 15-30 minutes before competition to enhance athletic performance and physical function.PROSPERO registration number CRD42023411381.

A chiral pentanidium and pyridinyl-sulphonamide ion pair as an enantioselective organocatalyst for Steglich rearrangement.

Enantioselective ion pair catalysis has gained significant attention due to its ability to exert selectivity control in various reactions. Achiral counterions have been found to play crucial roles in modulating reactivity and selectivity. The modular nature of an ion pair catalyst allows rapid alterations of the achiral counterion to achieve optimal outcomes, without the need to modify the more onerous chiral component. In this study, we report the successful development of a stable chiral pentanidium pyridinyl-sulphonamide ion pair as a nucleophilic organocatalyst for asymmetric Steglich rearrangement. The ion pair catalyst demonstrated excellent performance, leading to enantioenriched products with up to 99% ee through simple alterations of the achiral anions. We conducted extensive ROESY experiments and concluded that the reactivity and enantioselectivity were correlated to the formation of a tight ion pair in solution. Further computational analyses provided greater clarity to the structure of the ion pair catalyst in solution. Our findings reveal the critical roles of NMR experiments and computational analyses in the design and optimisation of ion pair catalysts.

Effect of exercise intervention on depression in children and adolescents: a systematic review and network meta-analysis.

OBJECTIVES: To evaluate the effect of different exercise interventions on depressive symptoms in children and adolescents. METHODS: Randomized controlled trials (RCT) published until May 2023 were screened in four databases. The Cochrane collaboration tool was used to assess the risk of bias for quality evaluation. Stata 16.0 software was used for both a pairwise meta-analysis and a series of frequentist network meta-analyses (NMA). RESULTS: A total of 35 RCTs and 5393 participants were included. Aerobic exercise had the most significant effect on depressive symptoms (66.2%), followed by group training (62.5%), resistance exercise (59.0%), and aerobic combined with resistance exercise (57.9%). Furthermore, children and adolescents younger than 15 years showed significant improvement in depressive symptoms (SMD=-0.41, 95% CI (-0.63, -0.19), P < 0.01). The study also found a significant improvement in depression among healthy, obesity, and depressed populations (SMD=-0.25, 95% CI (-0.41, -0.08), P < 0.01); SMD=-0.15, 95% CI (-0.31, -0.00), P < 0.01; SMD=-0.75, 95% CI (-1.32, -0.19), P < 0.01). Additionally, 30 min of exercise had a significant effect (SMD=-0.14, 95% CI (-0,81, -0.01), P < 0.01), and 40-50 min of exercise had the best effect (SMD=-0.17, 95% CI (-0,33, -0.02), P < 0.01). Lastly, exercise frequency of three times per week was significant in children and adolescents (SMD=-0.42, 95% CI (-0,66, -0.18), P < 0.01). CONCLUSION: Exercise significantly improves depressive symptoms in children and adolescents, with aerobic exercise having the most significant effect. A 12-week, three-times-a-week, 40-50-minute exercise intervention was found to be more effective in younger children and adolescents.

Effect of exercise intervention on depression in children and adolescents: A systematic review and network meta-analysis.

OBJECTIVES: To evaluate the effect of different exercise interventions on depressive symptoms in children and adolescents. METHODS: Randomized controlled trials (RCT) published until May 2023 were screened in four databases. The Cochrane collaboration tool was used to assess the risk of bias for quality evaluation. Stata 16.0 software was used for both a pairwise meta-analysis and a series of frequentist network meta-analyses (NMA). RESULTS: A total of 35 RCTs and 5393 participants were included. Aerobic exercise had the most significant effect on depressive symptoms (66.2 %), followed by group training (62.5 %), resistance exercise (59.0 %), and aerobic combined with resistance exercise (57.9 %). Furthermore, children and adolescents younger than 15 years showed significant improvement in depressive symptoms (SMD = -0.41, 95 % CI (-0.63, -0.19), P < 0.01). The study also found a significant improvement in depression among healthy, obesity, and depressed populations (SMD = -0.25, 95 % CI (-0.41, -0.08), P < 0.01); SMD = -0.15, 95 % CI (-0.31, -0.00), P < 0.01; SMD = -0.75, 95 % CI (-1.32, -0.19), P < 0.01). Additionally, 30 min of exercise had a significant effect (SMD = -0.14, 95 % CI (-0,81, -0.01), P < 0.01), and 40-50 min of exercise had the best effect (SMD = -0.17, 95 % CI (-0,33, -0.02), P < 0.01). Lastly, exercise frequency of three times per week was significant in children and adolescents (SMD = -0.42, 95 % CI (-0,66, -0.18), P < 0.01). CONCLUSION: Exercise significantly improves depressive symptoms in children and adolescents, with aerobic exercise having the most significant effect. A 12-week, three-times-a-week, 40-50-min exercise intervention was found to be more effective in younger children and adolescents.

"Wane and wax" strategy: Enhanced evolution kinetics of liquid phase Li2S4 to Li2S via mutually embedded CNT sponge/Ni-porous carbon electrocatalysts.

The lithium-sulfur battery (Li-S) has been considered a promising energy storage system, however, in the practical application of Li-S batteries, considerable challenges remain. One challenge is the low kinetics involved in the conversion of Li2S4 to Li2S. Here, we reveal that highly dispersed Ni nanoparticles play a unique role in the reduction of Li2S4. Ni-porous carbon (Ni-PC) decorated in situ on a free-standing carbon nanotube sponge (CNTS/Ni-PC) enriches the current response of liquid phase Li2S4 and Li2S2 around the cathode more than 8.1 and 5.7 times higher than that of the CNTS blank sample, respectively, greatly boosting the kinetics and decreasing the reaction overpotential of Li2S4 reduction (lower Tafel slope and larger current response). Thus, with the same total overpotential, more space is provided for the concentration difference overpotential, allowing the more soluble polysulfide intermediates farther away from the surface of the conductive materials to be reduced based on the "wane and wax" strategy, and significantly improving the sulfur utilization. Consequently, S@CNTS/Ni-PC delivers excellent rate performance (812.4 mAh·g-1 at 2C) and a remarkable areal capacity of 10.1 mAh·cm-2. This work provides a viable strategy for designing a target catalyst to enhance the conversion kinetics in the Li2S4 reduction process.

High-Discrimination Comparison Algorithm for the Comprehensive Evaluation of Innovation Ability in Colleges and Universities under Uncertain Information.

The innovation ability of students is one of the most important objectives that need to be cultivated in colleges and universities. The comprehensive evaluation of innovation ability discussed in the study can be divided into two stages: the first stage can be called preliminary evaluation and its main target is to identify students with innovative potential; in the second stage, the target objects found in the previous stage will be evaluated quantitatively and ranked. However, it is always difficult to quantitatively evaluate the innovation ability by using traditional algorithms. Based on the above analysis, the study proposes an algorithm to quantitatively evaluate the innovation ability with the help of management thought and fuzzy mathematics. Data are the basis of evaluation, and the accuracy of the data directly determines the quality of the algorithm; the data structure of the incompletely probabilistic fuzzy set is proposed in the study; the data structure can fully consider the fuzziness of the problem and the hesitation in the decision-making process; it can save the original detailed data to the maximum extent. Certainly, certain information may be lost or only the value range can be determined; there are usually some unknowns in the evaluation data, and the consistency optimization model is proposed for solving the problem. Usually, there are certain contradictions among the evaluation data; the definition of the consistency degree is proposed in the study; the consistency can be verified in time after all the unknowns are obtained, and the automatic adjustment module will be activated immediately if the value of the consistency degree exceeds the warning threshold. Finally, after verifying the data consistency, the solution can be obtained by solving the optimization model. Several experiments have been carried out to verify the effectiveness and high-discrimination ability of the algorithm proposed in the study; meanwhile, the superiority of the algorithm is further verified through comparisons with other outstanding algorithms.

A Closed-Loop Method for Multiperiod Intelligent Information Processing with Cost Constraints under the Fuzzy Environment.

From trivial matters in life to major scientific projects related to the fate of mankind, decision-making is everywhere. Whether high-quality decisions can be made often directly affects the development of affairs, especially when sudden disasters occur. As the basis of decision-making, data are crucial. The continuously probabilistic linguistic set, a data structure of the fuzzy mathematics, is selected in the paper to collect original data after careful comparisons, because this data structure can fully consider the hesitation of decision-makers and the fuzziness of complex problems. Although all alternatives are costly, the costs of different alternatives still vary greatly; obviously, the low-cost alternative is better than others when the same predetermined goal can be achieved, which is one of the research objectives and characteristics of this paper. Different from other researchers who only take the cost as one of the decision-making indicators, the algorithm proposed in the paper pays much more attention on the cost reduction. When dealing with an emergency, it is often difficult to solve the problem by taking measures only once; usually, multiple rounds of measures are needed. Each round of decision-making has both connections and differences, and the multiround decision-making model is proposed and built in the paper. Different from traditional linear structures, the model mainly adopts the closed-loop structure, which divides the whole process into multiple sub-decision-making points, the severities measured at the current time point will be compared with the values estimated at the latter time point, and then, the differences will be input into the system, the corresponding automatic adjustment modules will be activated immediately according to the values. The accuracy of the system can be verified and adjusted in time by the closed-loop control module. Finally, several experiments are carried out and the results show that the algorithm proposed in the paper is more effective and the cost is lower.

Electrochemical Modification on CH4 and H2O Wettability of Qinshui Anthracite Coal: A Combined Experimental and Molecular Dynamics Simulation Study.

The wettability of gas and liquid on the coal surface is one of the fundamental factors that affect the depressurization process during the coalbed methane (CBM) extraction. The wettability of coal surface changed after electrochemical modification, leading to the change in methane adsorption/desorption and water movement in coal reservoirs. Thus, the CH4 adsorption amount, desorption ratio, and coal-water contact angle of raw and modified anthracite samples were measured and simulated. The mechanism of electrochemical modification was analyzed by functional groups, surface free energy, pore characteristics, interaction energies, and coal swelling. The experimental results showed that the saturated adsorption amount of methane decreased from 41.49 to 34.72 mL/g, and the simulation results showed that the saturated adsorption amount of methane decreased from 2.01 to 1.83 mmol/g. The coal-water contact angle also decreased from 81.9 to 68.6°. Electrochemical modification mainly affects the wettability of CH4 and H2O by changing the functional groups and pore structures of anthracite, and the influence on functional groups of coal surface is greater. This work provided a basis for enhancing CBM extraction by electrochemical modification.

Optimal Gestational Weight Gain for Tibetans Based on Prepregnancy Body Mass Index.

We aimed to estimate the optimal gestational weight gain (GWG) in Tibetan women and to evaluate the appropriateness of the Institute of Medicine (IOM) GWG recommendations for Tibetan women. We analyzed data from 1474 Tibetan women from a cross-sectional study conducted in 2019. According to the three different body mass index (BMI) classification criteria (WHO BMI categories, WHO Asian BMI categories, Chinese BMI categories), we estimated the association of GWG with pregnancy outcomes (neonate birthweight and mode of delivery) using a polynomial regression model, and the optimal GWG in each BMI group was calculated. The risk of adverse outcomes showed a U-shaped curve with increasing GWG. The optimal GWG of Tibetan women based on the WHO BMI categories was 17.2 kg (range, 13.3 to 20.9 kg) for underweight, 9.3 kg (5.8 to 12.9 kg) for normal weight, and 5.2 kg (1.3 to 9.1 kg) for overweight. Underweight Tibetan mothers may gain more gestational weight than recommend by the IOM guidelines. However, normal weight Tibetan mothers are likely to benefit from gaining less weight than that recommended by the IOM. The GWG recommendations based on the IOM guidelines might not be appropriate for Tibetan women, and ethnicity-specific recommendations for GWG should be properly addressed.

Phrenic nerve injury during right inferior pulmonary vein ablation with the second-generation cryoballoon: A report of 2 cases and literature review. / 第2代冷冻球囊消融右下肺静脉致膈神经损伤2ä¾‹åŠæ–‡çŒ®å¤ä¹ .

The performance of the second-generation cryoballoon has been greatly improved compared to the first-generation.But it has not reduced the incidence of phrenic nerve injury, and even increased the incidence of this complication during ablation of the right inferior pulmonary vein. Two cases of phrenic nerve injury occurred when right inferior pulmonary vein was ablated with the second-generation cryoballoon in Department of Cardiovascular Medicine, Second Xiangya Hospital, Central South University. Based on literature review, the possible causes for phrenic nerve injury in our report were summarized to provide helpful information for operators aiming to reduce the occurrence of this complication related to the second-generation cryoballoon.

Risk factors for recurrence of paroxysmal atrial fibrillation after second-generation of cryoballoon ablation. / 第2ä»£å†·å†»çƒå›Šæ¶ˆèžæ²»ç–—é˜µå‘æ€§å¿ƒæˆ¿é¢¤åŠ¨çš„å¤å‘é£Žé™©å› ç´ .

OBJECTIVES: To analyze the risk factors for recurrence of paroxysmal atrial fibrillation (PAF) after the second-generation of cryoballoon ablation (CBA). METHODS: A total of 67 patients with PAF, who underwent CBA treatment from March 2017 to June 2018, were selected from the Department of Cardiology, Second Xiangya Hospital of Central South University. The incidence rate of early recurrence (within 3 months) and late recurrence (after 3 months) in patients with PAF were analyzed retrospectively and the risk factors for recurrence were discussed. RESULTS: Among the 67 patients, 40 were males (59.7%). The patients were at 34-84 (58.91±10.49) years old and followed up for 4-15 (9.04±4.66) months. Fifteen (22.4%) patients suffered early recurrence, and 16 (23.9%) patients suffered late recurrence. Among the 16 patients with late recurrence, 12 suffered early recurrence. The results of univariate analysis showed that there were significant differences between the early recurrence group and the non-early recurrence group in the freezing temperature of right inferior pulmonary vein at 30 s and right superior pulmonary vein at 60 s, the nadir freezing temperature of right inferior pulmonary vein and the width of left inferior pulmonary vein (all P<0.05); there were significant differences between the late recurrence group and the non-late recurrence group in the left atrial diameter, early recurrence and the nadir temperature of left superior pulmonary vein (all P<0.05). Multivariate analysis found that the freezing temperature of right superior pulmonary vein at 60 s was an independent risk factor for early recurrence (OR=1.108, 95% CI 1.002 to 1.225, P=0.046); and early recurrence was an independent risk factor for late recurrence (OR=24.94, 95% CI 7.85 to 41.91, P=0.020). CONCLUSIONS: Freezing temperature of right superior pulmonary vein at 60 s is an independent risk factor of early recurrence, and early recurrence is an independent risk factor of late recurrence after the second-generation cryoballon ablation for PAF.