ABSTRACT
Primary localized cutaneous amyloidosis is a skin-limited amyloidosis that does not involve internal organs. It is clinically subclassified into 3 general categories and some rare variants. However, there is considerable overlap within the classification. Though there are a variety of therapeutic measures, the treatment is often unsatisfactory, particularly when the disease is severe and extensive. We describe a rare case of primary localized cutaneous amyloidosis with lichen and poikiloderma-like lesions that showed an excellent response to systemic acitretin.
Subject(s)
Acitretin/therapeutic use , Amyloidosis, Familial/drug therapy , Keratolytic Agents/therapeutic use , Skin Diseases, Genetic/drug therapy , Amyloidosis, Familial/complications , Amyloidosis, Familial/diagnosis , Female , Humans , Lichenoid Eruptions/complications , Lichenoid Eruptions/drug therapy , Skin Diseases, Genetic/complications , Skin Diseases, Genetic/diagnosis , Treatment Outcome , Young AdultABSTRACT
Abstract: Primary localized cutaneous amyloidosis is a skin-limited amyloidosis that does not involve internal organs. It is clinically subclassified into 3 general categories and some rare variants. However, there is considerable overlap within the classification. Though there are a variety of therapeutic measures, the treatment is often unsatisfactory, particularly when the disease is severe and extensive. We describe a rare case of primary localized cutaneous amyloidosis with lichen and poikiloderma-like lesions that showed an excellent response to systemic acitretin.