ABSTRACT
PURPOSE: To assess the function of inguinal lymph node (ILN) in low extremity lymphedema (LEL) with dynamic enhanced MR lymphangiography (MRL). MATERIALS AND METHODS: Sixty-four patients with clinically diagnosed LEL underwent MRL examinations. The lymph drainage patterns were separated into four subtypes. The peak time to enhancement and the contrast ratio of the ILN were calculated 35 min following contrast agent administration. RESULTS: Dilated lymphatic vessels could be observed in all subjects. Type I-IV drainage patterns were observed 25% (16/64), 45.31% (29/64), 17.19% (11/64), and 12.5% (8/64), respectively. The ILN in the edematous limbs could be observed in 93.75% (60/64) of subjects. The peak time to enhancement was correlated with clinical stages (P < 0.001) of the disease, lymph drainage patterns (P < 0.001), and the duration of lymphedema (P < 0.001). The contrast ratios were significantly different at each time point (P < 0.001) and significantly correlated with the lymphatic drainage patterns (P < 0.001). CONCLUSION: MRL could provide useful information for evaluating the functional status of the ILN. Data presented here demonstrate that the functionality of the ILN is related to the clinical stage of the disease, lymphatic drainage patterns, and the duration of lymphedema.
Subject(s)
Image Interpretation, Computer-Assisted/methods , Inguinal Canal/pathology , Lower Extremity/pathology , Lymphedema/pathology , Lymphography/methods , Magnetic Resonance Imaging/methods , Meglumine/analogs & derivatives , Organometallic Compounds , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Contrast Media , Female , Humans , Image Enhancement/methods , Male , Middle Aged , Reproducibility of Results , Sensitivity and Specificity , Young AdultABSTRACT
BACKGROUND: Recognizing renal vascular variants preoperatively is important in order to avoid vascular complications during surgery. This study aimed to investigate the renal vascular variants with dual-energy computed tomography (DECT) angiography to provide valuable information for surgery. METHODS: A total of 378 patients underwent DECT. The number, size, course and relationships of the renal vessels were retrospectively observed from the scans. Anomalies of renal arteries and veins were recorded and classified. Multiplanar reformations (MPR), maximum intensity projections (MIP), and volume renderings (VR) were used for analysis. RESULTS: In 378 patients (756 kidneys), renal artery variations were discovered and recorded in 123 kidneys (16.3%, 123/756) of 106 patients (28.0%, 106/378). Type IB (early branches of the only one main renal artery) and IC (accessory renal artery with only one main renal artery) were found most frequently with an incidence of 11.4% (43/378) and 14.5% (55/378). The incidence of renal artery variations in the left kidney was not statistically different than in the right kidney (12.4% vs. 11.1%). The incidence of renal vein variations was detected in 104 patients (27.5%, 104/378). The incidence of venous variants in the right kidney was higher than in the left kidney (20.1% vs. 7.4%), but left renal vein variations were more complex. Variants of the left renal vein were detected in 28 patients including type 1 (circumaortic left renal vein) in eight cases, type 2 (retroaortic left renal vein) in seven cases, type 3 (abnormal reflux) in six cases, type 4 (late venous confluence of left renal vein) in five cases, and type 5 (rare type) in two cases. The frequency of left renal vein variation associated with the left renal accessory artery was significantly higher than with early branches of the left renal artery (P = 0.037). CONCLUSIONS: The renal vascular variants are rather common and complex. DECT angiography can demonstrate the precise anatomy of the renal vessels, which is a benefit for renal transplantation or other renal operations.
Subject(s)
Angiography/methods , Kidney/blood supply , Radiography, Dual-Energy Scanned Projection/methods , Renal Veins/diagnostic imaging , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Retrospective Studies , Young AdultABSTRACT
The authors report a 12-mo-old girl with calcified cerebral cryptococcal granuloma. She was admitted with a 6-mo history of seizures. Laboratory examinations showed no abnormal findings. Electroencephalography revealed bilateral slow wave activity, greater in the right occipital region. CT showed an irregular calcified focus with small surrounding low density in the right parieto-occipital region. MRI demonstrated mixed signals without edema and visible flow-voids. The clinical symptoms mimicked intracranial vascular malformations. The diagnosis of cerebral cryptococcal granuloma was made by histopathology. Partial resection of the lesion with post-operatively antifungal and anticonvulsant therapy offered the satisfactory result. Cerebral cryptococcal granuloma is extremely rare, especially in infants. Calcification is indeed unusual. Cerebral cryptococcal granuloma should be included in the differential diagnosis of intracranial mass with calcification in infants.
Subject(s)
Brain Diseases/diagnosis , Calcinosis/diagnosis , Cryptococcus , Eosinophilic Granuloma/diagnosis , Parietal Lobe/diagnostic imaging , Parietal Lobe/pathology , Brain Diseases/complications , Brain Diseases/microbiology , Brain Diseases/surgery , Calcinosis/complications , Calcinosis/surgery , Child, Preschool , Cryptococcus/isolation & purification , Diagnosis, Differential , Electroencephalography , Eosinophilic Granuloma/complications , Eosinophilic Granuloma/microbiology , Eosinophilic Granuloma/surgery , Female , Humans , Magnetic Resonance Imaging , Neurosurgical Procedures/methods , Parietal Lobe/surgery , Patient Readmission , Seizures/etiology , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
OBJECTIVE: To explore the value of apparent diffusion coefficient (ADC) ratio in the diagnosis of bladder cancer pre-operation by analyzing its differences among different grades of bladder cancer. METHODS: A total of 52 cases of bladder cancer were all definitely diagnosed with histological results.Routine examinations of magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) were performed preoperatively on each patient. ADC map was constructed in work station and ADC values of tumor and internal obturator muscle were measured (b = 800 s/mm(2)).Ratio of ADC was calculated with internal obturator muscle as reference site. Then the relationship between ADC ratio and bladder cancer grade was analyzed. RESULTS: Mean ratio of ADC of all tumors was 0.98±0.35, G1 (1.12±0.21) and G2 (0.67±0.29), the sensitivity and specificity of ADC ratio was 90.2% and 85.3% respectively with an optimal threshold of 0.96. The ratios of ADC of low-grade group were significantly higher than those of high-grade group while the values of non-muscle-invasive group were significantly higher than those of muscle-invasive group. The ratios of ADC of tumor were inversely associated with the malignancy degree of bladder cancer (r = -0.845, P < 0.05). CONCLUSION: The ratio of ADC of bladder cancer reflects the lesion tissue properties. And its measurement plays an important role in the diagnosis of bladder cancer grading pre-operation.
Subject(s)
Diffusion Magnetic Resonance Imaging/methods , Urinary Bladder Neoplasms/diagnosis , Urinary Bladder Neoplasms/pathology , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Neoplasm GradingABSTRACT
BACKGROUND: Multiple calcified primary central nervous system lymphoma (PCNSL) is extremely rare in childhood. METHODS: We report a 4-year-old boy suffering from multiple calcified B-cell lymphoma in the brain with immunodeficiency. RESULTS: The boy had a history of walking weakness and seizure for 4 months. The serum levels of immunoglobulin G, A and M were decreased. Brain MRI showed multiple lesions which had ring enhancement. CT showed calcification in all of the lesions. The boy was firstly misdiagnosed with multiple chronic brain abscesses. Pathological analysis of biopsy confirmed the diagnosis of anaplastic diffuse large B-cell lymphoma. CONCLUSION: PCNSL should be included in the differential diagnosis of intracranial mass with calcification.