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Management of an Outbreak of Exophiala dermatitidis Bloodstream Infections at an Outpatient Oncology Clinic.
Vasquez, Amber; Zavasky, D; Chow, N A; Gade, L; Zlatanic, E; Elkind, S; Litvintseva, A P; Pappas, P G; Perfect, J R; Revankar, S; Lockhart, S R; Chiller, T; Ackelsberg, J; Vallabhaneni, S.
Clin Infect Dis ; 66(6): 959-962, 2018 03 05.
Article in English | MEDLINE | ID: mdl-29121235

ABSTRACT

We report the presentation and management of 17 cases of Exophiala dermatitidis and Rhodotorula mucilaginosa bloodstream infections caused by a compounded parenteral medication at an oncology clinic. Twelve patients were asymptomatic. All central venous catheters were removed and antifungal therapy, primarily voriconazole, was administered to patients. Three patients died.


Subject(s)
Disease Management , Disease Outbreaks , Drug Contamination , Fungemia/drug therapy , Phaeohyphomycosis/drug therapy , Aged , Ambulatory Care Facilities , Antifungal Agents/therapeutic use , Asymptomatic Infections , Exophiala/drug effects , Exophiala/isolation & purification , Female , Fungemia/mortality , Humans , Immunocompromised Host , Male , Middle Aged , Oncology Service, Hospital , Outpatients , Phaeohyphomycosis/mortality , Rhodotorula/drug effects , Rhodotorula/isolation & purification
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