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1.
Biomed Res Int ; 2018: 1809091, 2018.
Article in English | MEDLINE | ID: mdl-29854729

ABSTRACT

BACKGROUND: Healing of tibia fractures occurs over a wide time range of months, with a number of risk factors contributing to prolonged healing. In this prospective, multicentre, observational study, we investigated the capability of FRACTING (tibia FRACTure prediction healING days) score, calculated soon after tibia fracture treatment, to predict healing time. METHODS: The study included 363 patients. Information on patient health, fracture morphology, and surgical treatment adopted were combined to calculate the FRACTING score. Fractures were considered healed when the patient was able to fully weight-bear without pain. RESULTS: 319 fractures (88%) healed within 12 months from treatment. Forty-four fractures healed after 12 months or underwent a second surgery. FRACTING score positively correlated with days to healing: r = 0.63 (p < 0.0001). Average score value was 7.3 ± 2.5; ROC analysis showed strong reliability of the score in separating patients healing before versus after 6 months: AUC = 0.823. CONCLUSIONS: This study shows that the FRACTING score can be employed both to predict months needed for fracture healing and to identify immediately after treatment patients at risk of prolonged healing. In patients with high score values, new pharmacological and nonpharmacological treatments to enhance osteogenesis could be tested selectively, which may finally result in reduced disability time and health cost savings.


Subject(s)
Fracture Healing/physiology , Tibia/physiopathology , Tibia/surgery , Tibial Fractures/physiopathology , Tibial Fractures/surgery , Adolescent , Adult , Female , Humans , Male , Middle Aged , Osteogenesis/physiology , Prospective Studies , Reproducibility of Results , Treatment Outcome , Young Adult
2.
Int Orthop ; 36(4): 817-25, 2012 Apr.
Article in English | MEDLINE | ID: mdl-21505801

ABSTRACT

PURPOSE: This retrospective review follows 31 tibial nonunions to compare union at the docking site using closed versus open strategies. In this cohort of patients, all but five were infected nonunions. METHODS: Thirteen patients initially treated with single compression were compared with 18 patients treated by open revision of the docking site. In the single compression group, an average of 6.5 cm of bone was resected and index lengthening was 2.04. In the open revision group, a mean of 9.4 cm was resected and the index lengthening was 1.73. RESULTS: Consolidation at the docking site occurred in all subjects in both groups. There was no statistical difference between the two groups. Conclusive evidence of superiority of one modality of treatment over the other cannot be drawn from our data. CONCLUSIONS: The simple compression procedure requires less invasive surgery and is probably less demanding and more cost-effective in short transports.


Subject(s)
Fracture Fixation, Internal/methods , Fractures, Ununited/therapy , Manipulation, Orthopedic , Osteogenesis, Distraction/methods , Tibial Fractures/therapy , Adult , Aged , Bone Lengthening , Cost-Benefit Analysis , Female , Fracture Fixation, Internal/economics , Fracture Healing , Humans , Male , Middle Aged , Minimally Invasive Surgical Procedures , Osteogenesis/physiology , Osteogenesis, Distraction/economics , Osteotomy , Reoperation , Reproducibility of Results , Retrospective Studies , Young Adult
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