ABSTRACT
Paraneoplastic neurologic degeneration (PND) is characterized by acute and subacute onset neurological syndrome associated with active or with subclinical cancer. It is rare but early diagnosis can improve the neurological and carcinological prognosis. Among the PNDs it is possible to distinguish subacute cerebellar degeneration often associated with gynecological or breast cancer. We report the case of a 50-year old female patient on follow-up for ovarian adenocarcinoma treated with surgery and whose recurrence was detected due to anti-Yo antibody-positive subacute cerebellar degeneration.
Subject(s)
Adenocarcinoma/diagnosis , Ovarian Neoplasms/diagnosis , Paraneoplastic Cerebellar Degeneration/diagnosis , Adenocarcinoma/pathology , Female , Humans , Middle Aged , Neoplasm Recurrence, Local , Nerve Tissue Proteins/immunology , Ovarian Neoplasms/pathology , Paraneoplastic Cerebellar Degeneration/immunology , PrognosisABSTRACT
Desmoid tumors are rare benign neoplasms with an aggressive local growth. In children, intra-abdominal localization is less frequent and few reports exist in the literature about the management of DTs in those special patients. In our report, we describe a case of a 13-year old patient with a bifocal intra-abdominal DT, treated unsuccessfully with tamoxifene, and we discuss briefly the existing literature data.