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Arq Bras Cardiol ; 80(3): 279-88, 2003 Mar.
Article in English, Portuguese | MEDLINE | ID: mdl-12856271

ABSTRACT

OBJECTIVE: To determine the immediate behavior and the prognostic value in terms of late survival of serum troponin I measurement in patients undergoing myocardial revascularization surgery with extracorporeal circulation. METHODS: We studied 88 random patients, 65 (73.8%) of the male sex, who underwent myocardial revascularization surgery with extracorporeal circulation. Troponin measurements were performed as follows: in the preoperative period, right after intensive care unit admission, and on the first and second postoperative days. Values below 0.1 nanogram per milliliter (ng/mL) were considered normal. The cut points for late prognostic assessment were 0.5 ng/mL; 1 ng/mL; 2.5 ng/mL; and 5 ng/mL. RESULTS: The serum troponin I levels were elevated on the first postoperative day, suggesting the occurrence of specific myocardial damage. Patients with a poor prognosis could be identified, because the serum levels above 2.5 ng/mL and 5 ng/mL in the postoperative period resulted, respectively, in mortality rates of 33% and 50% in a maximum 6-month follow-up. CONCLUSION: Troponin I values around 2.5 ng/mL in the postoperative period should call attention to the need for more aggressive diagnostic or therapeutical measures.


Subject(s)
Myocardial Reperfusion Injury/blood , Myocardial Revascularization/mortality , Troponin I/blood , Biomarkers/blood , Brazil/epidemiology , Extracorporeal Circulation , Female , Follow-Up Studies , Humans , Male , Myocardial Ischemia/blood , Myocardial Ischemia/diagnosis , Myocardial Reperfusion Injury/diagnosis , Postoperative Complications , Predictive Value of Tests , Preoperative Care , Prognosis , Risk Assessment
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