The influence of gestational trimester, physical activity practice and weight gain on the low back and pelvic pain intensity in low risk pregnant women.

BACKGROUND: Low back and pelvic pain in pregnant women is a clinical condition of which the etiology is multifactorial. Thus, various variables can influence the low back and pelvic pain's intensity. OBJECTIVE: The purpose of this study was to analyze the influence of the gestational trimester, practice of physical activity and weight gain on the intensity of low back and pelvic pain in low risk pregnant women. METHODS: Two hundred and sixty-seven pregnant women participated in this study. The gestational age, body mass index, weight gain, physical activity practice and the low back and pelvic pain were evaluated. RESULTS: We found a significant difference (P= 0.02) in pain intensity, when comparing active and sedentary pregnant women. No significant differences were found when comparing pain intensity between the gestational trimesters (2ndversus 3rd; P= 0.60). There was no significant relation between the weight gain and pain intensity (r= 0.03 |P= 0.28). The multivariate analysis indicated that sedentary pregnant women have a higher risk (P= 0.001) of intense pain and the pain is not influenced by the weight gain (P= 0.08) and the gestational trimester (P= 0.98). CONCLUSIONS: Sedentary pregnant women have 30% more chances to have higher pain intensities when compared to the active women, regardless of the gestational trimester and weight gain.

Plasma zinc in institutionalized elderly individuals: Relation with immune and cardiometabolic biomarkers.

Changes in zinc metabolism caused by aging and the institutionalization process may contribute to zinc deficiency in elderly individuals. Hypozincemia results in changes in glycemic, lipid, and inflammatory profiles. The aim of this study was to evaluate plasma zinc concentrations and their relationships with sociodemographic, dietary, inflammatory, and cardiometabolic biomarkers in institutionalized elderly individuals. A cross-sectional study was carried out including 255 elderly adults living in nursing homes. The associations between plasma zinc and dietary zinc intake, sociodemographic indicators, and glycemic, lipid, and inflammatory biomarkers were evaluated. Independent variables were analyzed according to quartiles of plasma zinc concentrations (Q1: <71.1 µg/dL; Q2: 71.1-83.3 µg/dL; Q3: <83.3-93.7 µg/dL; Q4: >93.7 µg/dL). The relationship between plasma zinc concentrations and predictor variables was also tested. In Q1, higher concentrations of the following variables were observed, compared with those in other quartiles: total cholesterol and low-density lipoprotein cholesterol (LDL-c; Q1 > Q2, Q3, Q4; all p <0.001); triglycerides (Q1 > Q3, Q4; all p < 0.001); interleukin (IL)-6 (Q1 > Q3, Q4; p = 0.024 and p = 0.010, respectively); tumor necrosis factor (TNF)-α (Q1 > Q3, p = 0.003). A significant reduction in plasma zinc concentrations was observed with increasing age-adjusted institutionalization time (Δ = - 0.10; 95% confidence interval [CI]: -0.18 to -0.01). The concentrations of total cholesterol (Δ = - 0.19; 95% CI: -0.23 to -0.15), LDL-c (Δ = - 0.19; 95% CI: -0.23 to -0.15), triglycerides (Δ = - 0.11; 95% CI: -0.16 to -0.06), IL-6 (Δ = - 1.41; 95% CI: -2.64 to -0.18), and TNF-α (Δ = - 1.04; 95% CI: -1.71 to -0.36) were also significantly increased. In conclusion, decreased plasma zinc concentrations were associated with longer institutionalization time and worse lipid and inflammatory profiles in elderly institutionalized individuals.