Tenosynovial chondromatosis of the wrist: A case report.

We report the case of an 80-year-old woman who presented with an asymptomatic slowly growing mass in the dorsal aspect of her right wrist. Radiographs revealed a snail-shaped radiopaque structure. Surgical exploration and excision revealed a calcified lesion over the extensor digitorum communis. Histopathological analysis confirmed the diagnosis of tenosynovial chondromatosis. At the last follow-up, four years after surgery, the patient was asymptomatic and free of recurrence. Practitioners and hand surgeons should be aware of the dorsal involvement and evocative radiological calcifications of tenosynovial chondromatosis, which is a rare benign soft tissue neoplasm that affects all tendon sheaths of the hand.

[Soft tissue tumours with FN1 (Fibronectin 1) fusion gene]. / Tumeurs des tissus mous avec fusion du gène FN1 (Fibronectine 1).

Translocations involving FN1 gene have been described in several tumours, which share the presence of a cartilaginous matrix with or without calcifications and a good prognosis. They encompass: soft tissue chondroma, synovial chondromatosis, calcifying aponeurotic fibroma, phosphaturic mesenchymal tumour and a new spectrum of tumours: "the calcified chondroid mesenchymal neoplasms". We review all the clinical, histopathological and molecular data of these tumours and discuss the differential diagnoses.

[Tumors affecting the temporomandibular joint - a literature review]. / Tumeurs de l'articulation temporomandibulaire ­ revue de la littérature.

Benign and malign tumors can affect the temporomandibular joint (TMJ) as any other articulation. Nevertheless, TMJ tumors are rare and mostly benign. Their clinical expression is varied including symptomatology similar to TMJ dysfunctional disorders, otologic or neurologic pathologies. In some cases, they remain totally asymptomatic. Hence, diagnosis is difficult since the symptomatology can be misleading with TMJ dysfunctional disorders or otologic disorders wrongly diagnosed. There is thus frequently a long delay between symptoms onset and diagnosis. The great variety of TMJ lesions explains the wide range of possible treatment modalities, mostly based on surgery. We provide here a review of the lesions originating from the TMJ. Tumoral or cystic mandibular lesion affecting the TMJ through local extension will not be discussed. Osteoma, osteoid osteoma, osteoblastoma, chondroma, osteochondroma, chondroblastoma, tenosynovial giant cell tumors, giant cell lesions, non-ossifying fibroma, hemangioma, lipoma or Langerhans cell histiocytosis are all possible diagnosis among the benign tumors found in the TMJ. Pseudotumors include synovial chondromatosis and aneurysmal bone cyst. Finally, malign tumors of the TMJ include mainly sarcomas (osteosarcoma, chondrosarcoma, synovial sarcoma, Ewing sarcoma, and fibrosarcoma), but also multiple myeloma and secondary metastases. We will review the clinical, radiological and histological aspects of each of these lesions. The treatment and the recurrence risk will also be discussed.

Tenosynovial chondromatosis of the wrist presenting with acute carpal tunnel syndrome: A case report.

We report a case of synovial chondromatosis of the wrist that manifested as acute carpal tunnel syndrome. The patient successfully underwent carpal tunnel release, tenosynovectomy and resection of dorsal and volar ossified bodies embedded in the tenosynovium overlying the wrist. Final histopathology confirmed the diagnosis of synovial chondromatosis. The patient's symptoms of pain, numbness, and paresthesia in a median nerve distribution resolved completely and the patient resumed full-time work in the service industry 4-weeks postoperatively with no functional limitations. This case highlights the importance of maintaining a broad differential in the approach to wrist pain and the role of magnetic resonance imaging in the diagnosis of synovial chondromatosis given its variable degree of ossification.

[Chondromatose of the temporomandibular joint: Multicentric study and clarification from 14 cases]. / Chondromatose de l'articulation temporomandibulaire : étude multicentrique et mise au point à partir de 14 cas.

INTRODUCTION: The aim of our study was to analyse a series of patients suffering from temporomandibular joint (TMJ) chondromatosis treated in 2 departments of stomatology and maxillofacial surgery (University hospitals of the Conception in Marseille and of Caen) and to make a general review of this disease. MATERIAL AND METHODS: We conducted a retrospective study including all the patients treated for a TMJ chondromatosis in one of these 2 departments. Following parameters were analyzed: sex, ages at discovery and at surgery, symptoms, side, imaging, histology, recurrence and any other events considered as relevant. RESULTS: Fourteen patients could be included: 85.7 % were women. Average age at diagnosis was 40.14 (σ = 13.82; IC95: 32.90-47.38) (41 for women [σ = 14.74; IC95: 33.28-48.72] and 35 years for men [σ = 5.66, IC95: 27.16-42.84]). Average age at surgery was 40.86 (σ = 14.18; IC95: 33.43-48.28). There was no predominance of side; 57.14 % of the patients had a joint syndrome, 57.14 % a tumor syndrome, 28.57 % had pain and 14.29 % had headaches. Panoramic X-ray was informative in 3 cases only. CT scan showed intra-articular calcifications in half of the cases only but arthrosic modifications in all the cases. Magnetic resonance imaging (MRI) constantly showed intra-articular cartilage fragments. When histology was performed, it found the synovial to be normal in one case and multiple nodules with clear cartilaginous differentiation in another case. One patient suffered from a second contralateral localization 10 years later. DISCUSSION: Chondromatosis has a slow evolution and is asymptomatic for a long time. MRI allows to evoke the diagnosis and to locate precisely the osteochondromas. Diagnosis is confirmed by histology that highlights a synovial metaplasia and more or less calcified chondromas. The main differential diagnosis to be eliminated because of prognostic reasons is the synovial chondrosarcoma. Treatment consists in surgical removing of the chondromas. Evolution is usually favorable.

Condrometaplasia tenosinovial extraarticular / Extra-articular tenosynovitis chondrometaplasia / Chondrométaplasie ténosynoviale extraarticulaire

La condromatosis tenosinovial es una metaplasia idiopática benigna de la membrana sinovial. Se caracteriza por la formación de nódulos cartilaginosos en la membrana sinovial y en la cavidad articular. La localización extraarticular es un hallazgo poco frecuente. Los síntomas predominantes son dolor, inflamación y limitación de los movimientos. Los métodos diagnósticos más efectivos comprenden la radiología, la tomografía computarizada, la resonancia magnética y la ecografía. Se presenta un nuevo caso de condromatosis tenosinovial extraarticular, se incluyen imágenes diagnósticas, se exponen el tratamiento realizado y los resultados histológicos. Además se ofrece una revisión de la literatura médica sobre el tema.

Tenosynovitis chondromatosis is a benign idiopathic metaplasia os sinovial membrane. It is characterized by formation of cartilaginous nodules in synovial membrane and in the articular cavity. Extra-articular location is an infrequent finding. Predominant symptoms are: pain, inflammation and movements limitation. The more effective diagnostic methods include radiology, computed tomography, magnetic resonance and echography. This is a new case of extra-articular tensosynovial chondromatosis where diagnostic images are included, as well as the treatment applied and histological results. Also, a review of medical literature on this subject is offered.

La chondromatose ténosynoviale est une métaplasie idiopatique benigne de la membrane synoviale. Elle est caractérisée par la formation de nodules cartilagineux dans la membrane synoviale et dans la cavité articulaire. Sa localisation extraarticulaire est une anomalie très rare. Les symptômes prédominants sont la douleur, l'inflammation et la limitation des mouvements. Les méthodes diagnostiques les plus effectives comprennent la radiologie, la tomographie informatisée, la résonance magnétique et l'échographie. Un nouveau cas de chondromatose ténosynoviale extraarticulaire, dont les images diagnostiques sont inclues, est présenté; le traitement réalisé et les résultats histologiques sont exposés. Une revision de la littérature médicale est également présentée.