Combinação de terapia por ondas de choque extracorpórea e agulhamento seco no tratamento de lombalgia crônica incapacitante: um relato de caso / Combination of extracorporeal shockwave therapy and dry needling as treatment of disabling chronic low back pain: a case report

Paciente do sexo masculino, 55 anos, apresentava antecedente clínico de radiculopatia lombar abordado cirurgicamente (discectomia e artrodese L5-S1) em dezembro de 2021, com resolução completa da dor associada. Iniciou com quadro de dor pós-operatória de características distintas. A primeira sessão de tratamento iniciou-se com terapia por ondas de choque extracorpóreas focal direcionada ao quadrado lombar, glúteo médio, glúteo mínimo e região peritrocantérica à direita. Posteriormente, associou-se agulhamento seco em pontos-gatilho presentes nesses mesmos 3 músculos e também no ligamento sacrotuberal direito, junto à inserção do glúteo máximo direito. Numa reavaliação uma semana depois, o paciente referiu uma redução de 70% da intensidade da dor inicial. O mesmo tratamento foi repetido, com resolução completa dos sintomas no final da sessão. Três meses depois, o doente manteve o controle álgico e recuperou totalmente a sua funcionalidade e qualidade de vida anteriores. Neste caso de limitação funcional a longo prazo devido a dor lombar crônica, a combinação da terapia por ondas de choque extracorporais e do agulhamento seco resultou num método eficaz e rápido para obter o alívio da dor e restaurar a funcionalidade anterior. No entanto, são necessários mais estudos para investigar o impacto desta combinação de terapias no controle da dor e na perda de funcionalidade devido à dor lombar crônica.

Male patient, 55 years old, had a clinical background of lumbar radiculopathy and a surgical approach (L5-S1 discectomy and arthrodesis) in December of 2021, with complete resolution of associated pain. One year later, the patient seeks medical treatment, referring a new, different pattern of low back pain, which initiated post-surgery. The first treatment session began with focused extracorporeal shockwave therapy directed at the right quadratus lumborum, gluteus medius, gluteus minimus and peritrochanteric region. Afterwards, dry needling was associated in trigger-points present in those same 3 muscles and also in the right sacrotuberal ligament, close to the insertion of the right gluteus maximus. In a reevaluation one week later, the patient reported a reduction of 70% of initial pain intensity. The same treatment was repeated, with complete resolution of symptoms at the end of the session. Three months later, the patient-maintained symptom control and fully recovered his previous functionality and quality of life. In this case of long-term functional limitation due to chronic low back pain, the combination of extracorporeal shock wave therapy and dry needling resulted in an effective and quick method to achieve pain relief and restore previous functionality. However, more studies are needed to investigate the impact of this combination of therapies in pain management and functionality loss due to chronic low back pain.

Associação de estimulação por ondas de choque a toxina botulínica e baclofeno durante a reabilitação de paciente com lesão medular e trauma cranioencefálico: relato de caso / Association of extracorporeal shockwave stimulation to botulinum toxin and baclofen during an in-patient rehabilitation in spinal cord injury and traumatic brain injury: case report

Recentemente, a terapia por ondas de choque extracorpóreas (TOCE) mostraram-se ser uma promissora tecnologia não invasiva para neuromodulação e recuperação funcional devido a melhora em brotamento neuronal, neuroproteção, controle de neuroplasticidade e reorganização neuronal, além de atuar em fatores de neurogênese. Objetivo: Descrever um caso que usa TOCE como um adjuvante na reabilitação de trauma medular. Relato de caso: LPS, 25 anos, estudante de medicina, sofreu uma queda de altura indeterminada com fratura de C5 e lesão medular associada a trauma cranioencefálico. Na fase aguda, ele se recuperou adequadamente, tendo sido submetido a descompressão e fixação de coluna e hospitalizado por 5 meses devido a disautonomias e infecções urinárias. Após esse período, ele iniciou um programa de reabilitação intensiva para tetraplegia espástica com classificação inicial segundo o ASIA (American Spinal Injury Association) nível C5 motor e C6 sensório. O tratamento incluiu 10 sessões de TOCE, realizadas com Duolith SD1 (Storz Medical, Suíça) com uma densidade de energia de 0,25mJ/mm², 5 cm e 3 cm de profundidade de foco, 2000 pulsos aplicados na linha média de coluna níveis C5 a T1 e 2000 pulsos a 5 cm de profundidade aplicados em região plantar bilateral. Bloqueio com toxina botulínica e fenol foram realizados com resposta parcial apesar da dose otimizada de baclofeno.

Recently, extracorporeal shockwaves (ESWT) have shown as a promising non-invasive technology for neuromodulation and functional recovery, due to improving neuronal budding, neuroprotection, control of neuroplasticity and neuronal reorganization, in addition to acting on neurogenesis factors. Objective: To describe a case that uses ESWT as an adjuvant to the rehabilitation of spinal cord trauma. Case Report: LPS, 25 years old, medical student, suffered a fall from an undetermined height with C5 fracture and spinal cord injury, associated with a cranioencephalic trauma. In the acute phase, he was rescued properly, performed decompression and spinal cord fixation and remained hospitalized for 5 months due to dysautonomia and urinary infections. After this period, he started an intensive in-patient rehabilitation program for spastic tetraplegia with initial classification according to ASIA C5 (motor) and C6 (sensory). The treatment included 10 sessions of ESWT, made with Duolith SD1 (Storz Medical, Switzerland) with an Energy flux density 0,25 mJ/mm2, at 5cm and 3cm depth focus, 2000 pulses each over the spinal cord at the midline of levels from C5 to T1, and 2000 pulses at 5cm depth focus applied at plantar region bilaterally.

Estimulação cerebral por pulsos sonoros de baixa frequência como coadjuvante nas alterações das funções corticais superiores / Non-invasive brain stimulation by low-frequency sound pulses as an adjunct to changes in higher cortical functions

Não há dúvidas sobre os prejuízos na vida humana, extensivos à família e sociedade como um todo, abrangendo todos os aspectos funcionais das pessoas envolvidas, além do indivíduo, originados dos traumatismos cranioencefálico, agudos e crônicos, externos ou internos: acidentes, atropelamentos, quedas, crimes, acidente vascular cerebral, doenças com neurodegeneração progressiva, resultando em estados demenciais. Ao longo de meio século, houve a introdução contínua de medicamentos, com resultados usualmente contraditórios e frustrantes, exigindo novas tentativas com outras classes farmacológicas. No todo, a limitação se faz sentir na impossibilidade de reversão ou mesmo de mera estabilização dos danos neurológicos, e inocuidade em termos de estimulação da neuroplasticidade. Uma exceção parece ser uma nova abordagem: a estimulação cerebral profunda por pulsos sonoros de baixa frequência (Transcranial Pulse Stimulation, ou TPS). Ainda pouco conhecida, a não ser em alguns centros de tratamento, tem se mostrado ser um acréscimo válido, por complementar os programas multidisciplinares de reabilitação

There is no doubt about the damage to human life, also extended to family and society as a whole, regarding all the functional aspects of those involved, not only the patient itself, which originates from traumatic brain injury, acute or chronic, for external or internal reasons, such as accidents, run overs, falls, crimes, stroke, progressive neurodegenerative diseases that result in dementia states. Over half a century, drugs have been continuously introduced, however their results have constantly been contradictory and frustrating, requiring new attempts with other pharmacological classes. Overall, the limitation is felt in the impossibility of reversing or even merely stabilizing the neurological damage and inefficacy regarding neuroplasticity stimulation. One exception seems to be a new approach, the non-invasive brain stimulation by low-frequency sound pulses (Transcranial Pulse Stimulation, or TPS). Except for some treatment centers, TPS is still unknown, however it has shown to be a valid adjunct in multidisciplinary rehabilitation programs

Efectividad de la terapia por ondas de choque en lesiones de tendones y ligamentos del sistema osteomioarticular / Effectiveness of Shock Wave Therapy in Tendon and Ligament Injuries of the Osteomioarticular System

Introducción: Por más de 20 años la litotricia extracorpórea se ha aplicado con éxito en el mundo. Objetivo: Evaluar la efectividad de la terapia por ondas de choque en el tratamiento a pacientes que presentan lesiones en los tendones y ligamentos del sistema osteomioarticular. Métodos: Se realizó un estudio descriptivo, de corte transversal, con 107 pacientes diagnosticados con lesiones en los tendones y ligamentos del sistema osteomioarticular, los cuales fueron tratados con el equipo Well Wave (ondas de choque extracorpóreas) en el Complejo Científico Ortopédico Internacional Frank País, en el período comprendido entre marzo de 2019 y abril de 2020. Se realizó el análisis de las variables edad, sexo, dolor y discapacidad. Se obtuvieron frecuencias absolutas y relativas, y con ellas se confeccionaron las tablas que resumen la información estadística de la investigación. Resultados: Predominó el sexo femenino (71,9 por ciento), de 51 - 60 años (28 por ciento). El 40,2 por ciento de los pacientes fueron atendidos por presentar una tendinitis del supraespinoso. Todos los pacientes presentaban dolor antes de la aplicación de la terapia. Luego del tratamiento el 78,5 por ciento de los enfermos dejaron de sentirlo y el 71 por ciento presentó ausencia de discapacidad según escala de DASH. Según los criterios de evaluación de la respuesta al tratamiento los resultados fueron satisfactorios en el 56 por ciento de los pacientes. Conclusiones: La terapia con las ondas de choque posibilitó una rápida recuperación de los pacientes atendidos y su incorporación a las actividades diarias(AU)

ABSTRACT Introduction: Over more than 20 years, extracorporeal lithotripsy has been successfully used worldwide. Objective: To evaluate the effectiveness of shock wave therapy in the treatment of patients with injuries to the tendons and ligaments of the osteomioarticular system. Methods: A descriptive, cross-sectional study was carried out with 107 patients diagnosed with injuries to the tendons and ligaments of the osteomioarticular system. These subjects were treated with the Well Wave equipment (extracorporeal shock waves) at Frank País International Orthopedic Scientific Center, from March 2019 to April 2020. The variables age, sex, pain and disability were analyzed. Absolute and relative frequencies were obtained, and the results of statistical information of the investigation was shown in summarizing tables. Results: The female sex prevailed (71.9percent), 51 - 60 years old (28 percent). 40.2 percent of the patients were treated for supraspinatus tendinitis. All patients had pain before the use of therapy. After treatment, 78.5 percent of the patients stopped feeling pain and 71 percent showed no disability according to DASH scale. According to the treatment response evaluation criteria, the results were satisfactory in 56percent of the patients. Conclusions: This therapy enabled rapid recovery of the patients treated and their integration into daily activities(AU)

Influencia de la densidad de energía de ondas de choque focalizadas en el tratamiento de la fascitis plantar / Influence of energy density on the effectiveness of the treatment of plantar fasciitis with focused extracorporeal shock waves

Resumen La fascitis plantar (FP) es una patología frecuente e invalidante que puede tratarse con ondas de choque focalizadas. El objetivo principal del estudio fue valorar la eficacia del tratamiento con ondas de choque focalizadas en la FP según la densidad de energía utilizada. Se incluyeron 82 pacientes con diagnóstico clínico de FP que fueron asignados mediante muestreo aleatorio simple a dos grupos de tratamiento: densidad de energía media- alta (0,59mJ/mm2) y densidad de energía media-baja (0,27mJ/mm2). Se evaluaron el dolor y la funcionalidad, mediante las escalas EVA (Escala Visual Analógica) y AOFAS (American Orthopedic Foot and Ankle Society Ankle-Hindfoot Scale) respectivamente, al inicio del estudio (consulta base), y al primer, tercer y sexto mes tras el tratamiento. Por último, se evaluó el grado de satisfacción de los pacientes mediante la escala de Roles y Maudsley. Se compararon los resultados de las escalas en las revisiones posteriores al tratamiento, obteniéndose significación estadística para las variables principales del estudio (dolor y funcionalidad) en cada grupo de intervención. Aunque los niveles de dolor y la funcionalidad mejoraron en ambos grupos de estudio, se obtuvo una respuesta analgésica y funcional mayor y más precoz en el grupo tratado con densidad de energía media-alta.

Abstract Plantar fasciitis (FP) is a frequent and disabling condition that can be treated with focused extracorporeal shock waves. The main objective of this study was to assess the effectiveness of focused extracorporeal shockwave treatment in FP according to the energy density used. Eighty-two patients with a clinical diagnosis of FP were included and assigned, by simple random sampling, to two treatment groups: medium-high energy density (0.59mJ/mm2) and low-medium energy density (0.27mJ/mm2). Pain and functionality were assessed using the VAS (Visual Analogical Scale) and AOFAS (American Orthopedic Foot and Ankle Society Ankle-Hindfoot Scale) scales, respectively, at the start of the study (baseline consultation), and at the first, third and sixth month post-treatment. Finally, the degree of patient satisfaction was evaluated using the Roles and Maudsley score. The results of the scales in the post-treatment reviews were compared, and statistical significance was obtained for the main study variables (pain and functionality) in each intervention group. Although pain levels and functionality improved in both study groups after treatment, a greater and earlier analgesic and functional response was obtained for the medium-high energy density group.

Extracorporeal shockwave therapy in shoulder injuries: prospective study / Uso de terapia de ondas de choque em doenças ortopédicas do ombro: estudo prospectivo

ABSTRACT Objective: To evaluate the functional results after the use of extracorporeal shockwave therapy (ESWT) in four groups of patients: tendinopathy, partial rotator cuff injury, adhesive capsulitis and calcareous tendinopathy of the rotator cuff at one month and three months after the end of treatment. Methods: Case series in which patients were evaluated according to the VAS of pain, range of motion of the shoulder, and functional questionnaires DASH and modified UCLA. Results: There was a significant increase in the measure of flexion, lateral rotation and shoulder abduction in the evaluations after treatment in relation to the baseline measurement (p < 0.001) and no evidence of significant difference was found between the post-treatment evaluations at one month and three months follow-up (p > 0.05). There was a significant reduction in the VAS score, increase in the UCLA score and a significant reduction in the DASH score in the post-treatment evaluations in relation to the baseline score (p < 0.001) and a significant improvement in the three-month evaluation in relation to one month (p < 0.05). Conclusion: Extracorporeal shockwave therapy proved to be efficient and safe in the treatment of shoulder pathologies, improving pain, range of motion and functional scores in all groups of patients evaluated in the study. Level of Evidence IV, Case series.

RESUMO Objetivo: Avaliar os resultados funcionais após uso de terapia de ondas de choque (TOC) em quatro grupos de pacientes: tendinopatia, lesão parcial de manguito rotador, capsulite adesiva e tendinopatia calcária do manguito rotador com 1 mês e 3 meses após término do tratamento. Métodos: Série de casos, na qual os pacientes foram avaliados de acordo com a EVA da dor, amplitude de movimento do ombro, e questionários funcionais DASH e UCLA modificados. Resultados: Houve aumento significativo das medidas de flexão, rotação lateral e abdução do ombro nas avaliações após tratamento, em relação à medida basal (p < 0,001) e não houve evidências de variação significativa entre as avaliações pós-tratamento com 1 mês e 3 meses de acompanhamento (p°> 0,05). Houve redução significativa do escore EVA, aumento do escore UCLA e redução significativa do escore DASH nas avaliações após tratamento em relação ao escore basal (p < 0,001) e melhora significativa na avaliação de três meses em relação a um mês (p < 0,05). Conclusão: A terapia de ondas de choque mostrou-se uma terapia eficiente e segura no tratamento das patologias do ombro, com melhora da dor, arco de movimento e escores funcionais em todos os grupos de pacientes avaliados no estudo. Nível de Evidência IV, Série de casos.

Rotura de tendones rotulianos como complicación de mala técnica de aplicación de ondas de presión radial. Reporte de dos casos / Patellar ligament rupture as a complication of poor application technique of radial pressure wave therapy. Report of two cases

RESUMEN La tendinopatía rotuliana se caracteriza por dolor anterior de la rodilla localizado en el polo inferior de la rótula en la unión del tendón rotuliano. Esta es, a menudo, una condición discapacitante que limita la calidad de vida de los pacientes, afecta su capacidad para participar en deportes e incluso dificulta sus actividades cotidianas. El tratamiento de ondas de choque extracorpóreas (ESWT por sus siglas en inglés) ha sido reconocido como una alternativa prometedora y segura para el tratamiento de diversos trastornos musculoesqueléticos, incluida la tendinopatía rotuliana crónica. Sin embargo, existe evidencia limitada con respecto a sus efectos secundarios, en particular las lesiones de tendones asociadas con ESWT. Según el conocimiento de los autores, este es el primer artículo que demuestra evidencia clínica y radiológica de dos pacientes sin factores de riesgo que presentan desgarros parciales del tendón rotuliano después de haber recibido terapia de ondas de presión radiales, también conocida como terapia de ondas de choque radiales, como tratamiento para la tendinopatía rotuliana. El tratamiento con ondas de choque debe ser aplicada por profesionales debidamente capacitados para que se cumplan los requisitos específicos necesarios para garantizar una técnica de aplicación adecuada, minimizar los posibles efectos adversos y mejorar la seguridad del paciente.

ABSTRACT Patellar tendinopathy is characterized by anterior knee pain located at the lower pole of the patella at the junction of the patellar tendon. This is often a disabling condition that limits patients' quality of life, affects their ability to participate in sports, and even hinders their normal daily activities. Extracorporeal shock wave therapy (ESWT) has been recognized as a promising and safe alternative for the treatment of various musculoskeletal disorders - including chronic patellar tendinopathy. However, there is limited evidence regarding its side effects, in particular ESWT-associated tendon injuries. To the authors' knowledge, this is the first report demonstrating clinical and radiological evidence of two patients without known risk factors for partial patellar tendon tears that developed this condition after the application of radial pressure wave therapy - also known as radial shock wave therapy - for patellar tendinopathy. ESWT must be applied by properly trained professionals so that specific requirements needed to guarantee an appropriate application technique, minimize possible adverse effects, and improve patient safety could be met.

Efectividad del tratamiento con ondas de choque en la fascitis plantar / Effectiveness of shock wave treatment in plantar fasciitis

Introducción. Existe una gran heterogeneidad en los estudios que abordan la efectividad e indicación del tratamiento con ondas de choque (OCH) en la fascitis plantar (FP) respecto a otros tratamientos alternativos. Objetivos. Evaluar la efectividad del tratamiento con OCH en pacientes con FP mediante las evidencias científicas más actuales y evaluar la eficacia de este tratamiento en comparación con otros tipos de terapias también empleadas en el manejo de esta inflamación. Materiales y métodos. Se realizó una búsqueda bibliográfica en las bases de datos PubMed y PEDro con los términos clave "shock wave" y "plantar fasciitis AND shock wave". Se selecciona- ron artículos publicados en español e inglés entre los años 2015 y 2019. Resultados. Tras aplicar los criterios de inclusión y exclusión y luego de eliminar los duplica- dos, se seleccionaron 13 estudios que englobaban una muestra total de 1.220 individuos y comparaban las OCH frente a placebo, OCH con ejercicios, ultrasonoterapia, laserterapia de bajo nivel e infiltración de corticoides y toxina botulínica. Conclusión. Las OCH constituyen un método eficaz y seguro para tratar la FP, siendo más efectivo que la ultrasonoterapia y la infiltración de toxina botulínica, aunque existe controversia en el resto de comparaciones. Su uso se aconseja asociado a un programa de ejercicios; sin embargo, es necesario realizar más estudios sobre esta técnica.

Introduction. There is great heterogeneity in the studies that address the effectiveness and indication of shock wave therapy (SWT) in plantar fasciitis (PF) with respect to other alternative treatments. Objectives. To evaluate the effectiveness of OCH treatment in patients with PF using the most current scientific evidence and to assess the efficacy of this treatment in comparison with other types of therapies also used in the management of this inflammation. Materials and methods. A literature search was performed in the PubMed and PEDro databases with the key terms "shock wave" and "plantar fasciitis AND shock wave". Articles published in Spanish and English between 2015 and 2019 were selected. Results. After applying the inclusion and exclusion criteria and after eliminating duplicates, 13 studies were selected that encompassed a total sample of 1,220 individuals and compared OCH versus placebo, OCH with exercises, ultrasound therapy, low-level laser therapy, and corticosteroid and botulinum toxin infiltration. Conclusion. OCH is an effective and safe method to treat PF, being more effective than ultrasound therapy and botulinum toxin infiltration, although there is controversy in the rest of the comparisons. Its use is recommended in association with an exercise program; however, further studies on this technique are needed.

Ondas de choque eletromagnéticas na Dermatologia: análise microscópica de sua interação com a possível redução do tecido adiposo em indivíduos obesos / Electromagnetic shock wave therapy in dermatology: Microscopic analysis of its interaction with the possible reduction of adipose tissue in obese individuals

Introdução: a obesidade é uma doença que afeta a saúde pública em nível mundial devido a suas comorbidades e ao risco de morte prematura. Diante disso, a tecnologia de terapia de ondas de choque extracorpóreas (ESWT) pode ser útil em seu tratamento e na prevenção de suas comorbidades. Objetivos: o objetivo foi avaliar se a ESWT é capaz de estimular a lipólise e/ou apoptose da célula adiposa de indivíduos obesos. Métodos: trata-se de um estudo comparativo de intervenção baseado em análises imuno- -histoquímicas de um conjunto de amostras de tecido subcutâneo de mulheres com obesidade, submetidas ao tratamento ESWT. O material biológico foi coletado no momento da cirurgia bariátrica. Resultados: 14 mulheres obesas foram incluídas na pesquisa. Foi evidenciada positividade na expressão de Casp3 (p<0,0001), cCasp3 (p<0,0024), macrófagos CD68+ (p<0,0001), HSL (p<0,0001) e adipofilina (p<0,0013) na amostra intervenção quando comparada ao controle. Conclusões: a ESWT estimula a apoptose com consequente lipólise do tipo autofágica no tecido adiposo de mulheres obesas. Assim, a ESWT pode ser considerada uma terapia adjuvante útil, segura e promissora para redução do tecido adiposo e, consequentemente, para prevenção e/ou tratamento de obesidade

Introduction: Obesity is a disease that affects public health worldwide due to its comorbidities and premature death risk. Therefore, extracorporeal shock wave therapy (ESWT) technology can help treat and prevent its comorbidities. Objective: This study aims to assess whether ESWT can stimulate lipolysis and/or apoptosis of the fat cells of obese individuals. Methods: This is a comparative interventional study based on immunohistochemical analyzes of a set of subcutaneous tissue samples from women with obesity submitted to ESWT treatment. The biological material was collected at the time of bariatric surgery. Results: The survey included 14 obese women. Positivity was shown in the expression of Casp3 (p<0.0001), cCasp3 (p<0.0024), CD68+ macrophages (p<0.0001), HSL (p<0.0001), and adipophilin (p<0.0013) in the intervention sample compared to the control. Conclusions: We conclude that ESWT stimulates apoptosis with consequent autophagic lipolysis in the adipose tissue of obese women. Thus, ESWT can be considered useful, safe, and promising adjuvant therapy for reducing adipose tissue and, consequently, for preventing and/or treating obesity.

Lesión del nervio cubital secundario a terapia de ondas de choque extracorpóreas radiales identificada con ultrasonografía de alta resolución: Reporte de caso / Ulnar Nerve Injury After Radial Extracorporeal Shock Wave Therapy Identified With High­Resolution Ultrasonography: Case Report

Mujer de 49 años fue evaluada por desarrollar dolor súbito a nivel de los epicóndilos mediales conjuntamente con entumecimiento y sensación de hormigueo en el cuarto y quinto dedos después de recibir terapia de ondas de choque extracorpóreas radiales (rESWT) como tratamiento para epicondilitis medial bilateral. El examen neurológico reveló signo de Tinel positivo, parestesia y una prueba de discriminación de dos puntos alterada sobre la región cubital del cuarto y quinto dedos. La ultrasonografía de alta resolución demostró hallazgos de lesión nerviosa periférica tales como hipoecogenicidad y aumento del diámetro de ambos nervios cubitales. La paciente mejoró únicamente tras recibir tratamiento conservador, demostrando así una aparente neuropatía compresiva bilateral aguda como resultado de la terapia. ESWT se utiliza como una alternativa prometedora para el tratamiento de diversos trastornos musculoesqueléticos; sin embargo, existe evidencia limitada con respecto a sus efectos secundarios, en particular la mononeuropatía periférica. Según el conocimiento de los autores, este es el primer reporte que demuestra un daño nervioso estructural después de rESWT con el uso de ultrasonografía de alta resolución.

A 49-year old woman was evaluated for developing bilateral acute medial elbow pain, numbness, and tingling sensation in the fourth and fifth fingers after receiving radial extracorporeal shock wave therapy (rESWT) for bilateral medial epicondylitis. Neurologic examination revealed the presence of Tinel's sign, paresthesia and impaired two-point discrimination testing over the ulnar side of the fourth and fifth fingers bilaterally. High-resolution ultrasonography demonstrated findings of nerve injury, such as hypoechogenicity and increased diameter of both ulnar nerves. After conservative treatment, the patient improved her condition demonstrating an apparently acute compressive nerve injury as a result of the therapy. ESWT is used as a promising alternative for the treatment of various musculoskeletal disorders; however, there is limited evidence regarding its side effects, in particular peripheral mononeuropathy. To the authors' knowledge, this is the first report demonstrating structural damage of a nerve after rESWT with the use of high-resolution ultrasonography.

Pancreatitis aguda como complicación infrecuente de litotricia extracorpórea por ondas de choque. Comunicación de un caso / Acute pancreatitis as an unusual complication of extracorporeal shock wave lithotripsy. A case report / Pancreatite aguda como complicação pouco frequente de litotrícia extracorpórea por ondas de choque. Comunicação de um caso

Resumen: La litotricia extracorpórea por ondas de choque para el tratamiento de la urolitiasis es un tratamiento ampliamente aceptado, pero no exento de complicaciones. La pancreatitis aguda que se desencadena inmediatamente posterior a este procedimiento es infrecuente, pero puede ser una complicación grave que amenaza la vida del paciente. La aparición aguda de dolor abdominal y vómitos en las horas posteriores al procedimiento, deben hacer al médico tratante sospechar esta complicación. Presentamos el caso de un paciente joven que luego de someterse a una sesión de litotricia para el tratamiento de una litiasis renal derecha instaló una pancreatitis aguda que requirió ingreso a terapia intensiva y que se suma a los escasos informes de casos publicados en la literatura médica.

Summary: Extracorporeal shock wave lithotripsy to treat urolithiasis is a widely aceptable treatment, although it may involve complications. Acute pancreatitis immediately after the procedures is rather unusual, but it may result in a serious life-threatening complication for patients. The appearance of severe pain and vomits a few hours after the procedure should make physicians suspicious of this complication. The study presents the case of a young patient who developed acute pancreatitis after undergoing lithotripsy to treat lithiasis in the right kidney, requiring his admission to the intensive care unit. This will add up to the scarce reports published in the medical literature.

Resumo: A litotrícia extracorpórea por ondas de choque para o tratamento da urolitíase é um tratamento amplamente aceito, mas não isento de complicações. A pancreatite aguda que se desencadeia imediatamente depois deste procedimento não é frequente, porém pode ser uma complicação grave que ameaça a vida do paciente. O surgimento súbito de dor abdominal e vómitos nas horas seguintes ao procedimento devem induzir à suspeita desta complicação. Apresentamos o caso de um paciente jovem que depois de uma sessão de litotrícia para o tratamento de uma litíase renal direita apresentou uma pancreatite aguda com posterior admissão a terapia intensiva; este caso se agrega aos poucos publicados na literatura médica.

Effectiveness of shockwave therapy in the treatment of plantar fasciitis / Eficácia da terapia por ondas de choque no tratamento de fasciíte plantar

ABSTRACT Objective: To evaluate the effectiveness of single-dose focal shockwave therapy in plantar fasciitis treatment. Methods: a primary, prospective study of a series of cases, conducted in the city of São Paulo, Brazil, by the Department of Orthopedics and Traumatology of the Universidade Federal de São Paulo, in Hospital São Paulo. All outcomes were measured at the time of inclusion of the patient in the study and at the post-intervention moments as it follows: three, six and twelve weeks. The VAS, AOFAS and SF-36 scales were applied by teams other than those who performed the SWT. Results: Data from 56 patients were collected during 2017 and 2018. There was improvement of the parameter evaluated (p < 0.005 and 95%CI) in all the periods in which the patients were reevaluated (3, 6 and 12 weeks), progressive improvement were observed in the three outcomes evaluated. Conclusion: Shock wave therapy was effective for plantar fasciitis treatment according to the proposed protocol considering pain, function and quality of life. Level of Evidence Ic, Case-series Study.

RESUMO Objetivo: Avaliar a eficácia da terapia de ondas de choque focais de dose única no tratamento de fasciíte plantar. Métodos: Um estudo primário e prospectivo de série de casos foi realizado na cidade de São Paulo, Brasil, pelo Departamento de Ortopedia e Traumatologia da Universidade Federal de São Paulo, no Hospital São Paulo. Todos os desfechos foram medidos no momento da inclusão do paciente no estudo e nos momentos pós-intervenção da seguinte forma: 3, 6 e 12 semanas. As escalas VAS, AOFAS e SF-36 foram aplicadas por equipes diferentes daquelas que realizaram o tratamento. Resultados: Dados de 56 pacientes foram coletados durante 2017 e 2018. Houve melhora do parâmetro avaliado (p < 0,005 e IC95%) em todos os períodos de reavaliação dos pacientes (3, 6 e 12 semanas), sendo observada a melhora progressiva nos três desfechos avaliados. Conclusão: A terapia por ondas de choque foi eficaz no tratamento da fasciíte plantar de acordo com o protocolo proposto, considerando dor, função e qualidade de vida. Nível de evidência Ic, Estudo de série de casos.

Manejo con ondas de choque radiales en fractura de múltiples metacarpianos con retardo de la consolidación / Management with radial shockwaves in fracture of multiple methacarpals with delay of consolidation

El proceso de consolidación de una fractura depende de muchos factores externos e internos del paciente, así como físicos y biológicos. Cuando se retarda tal proceso se pueden usar diferentes estrategias como cirugía, manejo expectante y ondas de choque buscando mejorar esa condición. Se presenta un paciente de 27 años quien sufrió accidente de trabajo con tres fracturas en mano izquierda y compromiso del 2o., 4o. y 5o. metacarpianos. La fractura del 4o. dedo consolidó adecuadamente, pero las del 2o. y 5o. no lo hicieron. Se dio manejo con ondas de choque radiales en seis sesiones a 2 Barr y 2.000 golpes, acompañado de dos sesiones de terapia física para el 2o. dedo, logrando un proceso exitoso de consolidación ósea, mientras que en el 5o. metacarpiano no lo hubo porque no se hizo esta intervención. Luego de este proceso el paciente volvió a sus actividades laborales mejorando inclusive los arcos de movimiento así como la capacidad de agarre y prensión. En el mismo paciente se asumió el 2o. dedo como intervención y el 5o. dedo como control, lográndose consolidación completa con ondas radiales, además de mejoría en los arcos de movimiento y la capacidad de hacer pinzas y prensión, aunque no hubo alivio de la algia. Se confirmó que las ondas de choque promovieron un adecuado proceso biológico de osteoformación que favoreció la consolidación. Se ha demostrado que el manejo con ondas de choque es un procedimiento terapéutico efectivo, se considera más económico y prácticamente libre de efectos secundarios que facilita la consolidación retardada en fracturas de huesos metacarpianos. Además de este proceso, comprobado mediante seguimiento radiográfico, también puede ayudar a mejorar la funcionalidad y el reintegro del paciente a las actividades diarias

The fracture healing process depends on many external and internal factors of the patient, as well as physical and biological factors. When this process is delayed, different strategies such as surgery, expectant management and shock waves can be used in order to improve this condition. We present a 27-year-old patient who suffered a work accident with three fractures in the left hand and involvement of the 2nd, 4th and 5th metacarpals. The fracture of the 4th finger consolidated adequately, but those of the 2nd and 5th did not. Radial shock wave therapy was given in six sessions at 2 Barr and 2,000 strokes, accompanied by two sessions of physical therapy for the 2nd finger, achieving a successful process of bone consolidation, while the 5th metacarpal did not consolidate because this intervention was not performed. After this process, the patient returned to his work activities, even improving the arches of movement as well as the ability to grip and grasp. In the same patient, the 2nd finger was taken as intervention and the 5th finger as control, achieving complete consolidation with radial waves, as well as improvement in the arches of movement and the ability to grip and grasp, although there was no relief of the algia. It was confirmed that shock waves promoted an adequate biological process of osteoformation that favored consolidation. Shock wave management has been shown to be an effective therapeutic procedure, considered to be more economical and practically free of side effects that facilitates delayed healing in metacarpal bone fractures. In addition to this process, proven by radiographic follow-up, it can also help to improve the patient's functionality and reintegration into daily activities.

Terapia con ondas de choque extracorpóreas como alternativa no quirúrgica para el síndrome de túnel del carpo / Extracorporeal shock wave therapy as a non- surgical alternative for carpal tunnel syndrome

Recientemente se han postulado las ondas de choque extracorpóreas como tratamiento para el síndrome de túnel del carpo, el cual ha demostrado ser eficaz, no invasivo y con pocos efectos adversos. Mujer de 49 años con síndrome de túnel del carpo bilateral moderado de tres años de evolución, sin mejoría con el tratamiento convencional y con criterios para manejo quirúrgico. Sin embargo, ante la negativa de la paciente se propone manejo conservador con una sesión de ondas de choque extracorpóreas radiales con 5.000 descargas, a 4 Bar de intensidad y frecuencia de 15 Hz. Seis meses después de la intervención se documenta recuperación en los parámetros neurofisiológicos a nivel bilateral, pero clínica y funcionalmente solo hubo mejoría completa en la mano izquierda, registrando empeoramiento en la mano derecha; por tal razón se realizó liberación quirúrgica con buenos resultados. En la actualidad la paciente se encuentra asintomática en ambas manos. El tratamiento con ondas de choque radiales se constituye en una alternativa efectiva para el manejo conservador del síndrome de túnel del carpo leve a moderado. Los pacientes presentan buena tolerancia, garantizando la adherencia a la intervención.

Recently, extracorporeal shock waves have been postulated as a treatment for carpal tunnel syndrome, which has been shown to be effective, noninvasive and with few adverse effects. A 49-year-old woman with moderate bilateral carpal tunnel syndrome of three years of evolution, with no improvement with conventional treatment and with criteria for surgical management. However, due to the patient's refusal, conservative management was proposed with a session of extracorporeal radial shock waves with 5,000 shocks, at 4 Bar intensity and frequency of 15 Hz. Six months after the intervention, recovery in the neurophysiological parameters at bilateral level was documented, but clinically and functionally there was only complete improvement in the left hand, registering worsening in the right hand; for this reason, surgical release was performed with good results. At present the patient is asymptomatic in both hands. Radial shock wave therapy is an effective alternative for the conservative management of mild to moderate carpal tunnel syndrome. Patients present good tolerance, guaranteeing adherence to the intervention.

Resultados de la terapia con ondas de choque extracorpórea de baja intensidad en pacientes con angina refractaria / Results of low intensity extracorporeal shock wave therapy in patients with refractory angina

RESUMEN Introducción: La terapia con ondas de choque extracorpórea de baja intensidad ha demostrado ser útil en el tratamiento de los pacientes con angina de pecho refractaria. Objetivo: Valorar los resultados de este tipo de terapia en pacientes con angina refractaria al tratamiento farmacológico. Método: Se realizó un estudio cuasiexperimental en 30 pacientes con angina de pecho refractaria a tratamiento, seleccionados de forma no probabilística a partir de los criterios de inclusión. A todos los pacientes se les aplicó terapia con ondas de choque extracorpórea de baja intensidad en el Cardiocentro Ernesto Guevara de Santa Clara, en el período comprendido de enero a diciembre de 2017. Se analizaron variables epidemiológicas, clínicas y ecocardiográficas al inicio del tratamiento y 6 meses después de concluido este. Resultados: Los resultados obtenidos demostraron una mejoría de la clase funcional (CF) de la Canadian Cardiovascular Society (CCS). Previo al tratamiento el 76,7% de los pacientes tenían una CF III y un 23,3% una CF IV, y a los 6 meses de concluida la terapia el 73,3% mejoró a la CF II y solo un 26,7% quedó en CF III. También se evidenció mejoría con respecto a parámetros ecocardiográficos como la motilidad regional y la fracción de eyección del ventrículo izquierdo, la cual, en los hombres, de una media al inicio de la terapia de un 37,81% alcanzó 44,14% a los 6 meses de concluida; y en las mujeres, de una media de 37,11% inicial llegó a 47,22% a los 6 meses después. Conclusiones: El tratamiento con ondas de choque constituye una alterativa terapéutica para los pacientes con angina refractaria.

ABSTRACT Introduction: Low intensity extracorporeal shock wave therapy has proven useful in the treatment of patients with refractory angina pectoris. Objective: To assess the results of this type of therapy in patients with refractory angina to drug treatment. Method: A quasi-experimental study was carried out in 30 patients with refractory angina pectoris to treatment, selected in a non-probabilistic way, taking into account the following inclusion criteria. All patients were applied low intensity extracorporeal shock wave therapy in the Cardiocentro Ernesto Guevara of Santa Clara, in the period from January to December 2017. Epidemiological, clinical and echocardiographic variables were analyzed at the beginning of the treatment and six months after it was completed. Results: The results obtained demonstrated an improvement of the functional class (FC) of the Canadian Cardiovascular Society (CCS). Previous to treatment, 76.7% of patients had a FC III and 23.3% a FC IV, and after six months of completed therapy, 73.3% improved to FC II and only 26.7 % remained in FC III. There was also an improvement with respect to echocardiographic parameters such as regional motility and left ventricular ejection fraction, which, in men, of an average at the start of therapy of 37.81% it reached 44.14% at six months of completed; and in women, of an average of 37.11% initially, it reached 47.22 % six months later. Conclusions: The treatment with shock waves represents a therapeutic alternative for patients with refractory angina.

Ondas de choque extracorpórea en el tratamiento de la bursitis trocantérica / Extracorporeal shock waves in the treatment of trochanteric bursitis

RESUMEN Introducción: La terapia con ondas de choque son ondas acústicas presentes en situaciones diarias. Es un método que se emplea en la actualidad para tratar la bursitis trocantérica. Objetivo: Evaluar la efectividad de la terapia con ondas de choque en el tratamiento de la bursitis trocantérica. Métodos: Se realizó un estudio descriptivo, de corte transversal, con 46 pacientes diagnosticados con bursitis trocantérica, los cuales fueron tratados con el equipo Piezolith-3000 (ondas de choque extracorpóreas) en el Complejo Científico Ortopédico Internacional "Frank País", en el periodo comprendido entre marzo de 2014 y abril de 2018. Se realizó el análisis de las variables (edad, sexo, dolor y escala de Harris). Se obtuvieron las frecuencias absolutas y relativas, y con ellas se confeccionaron las tablas y gráficos que resumen la información estadística de la investigación. Resultados: Hubo predominio del sexo femenino (86,9 por ciento) y del grupo etario de 46 - 55 años (50 por ciento). Todos los pacientes presentaban dolor antes de la aplicación de las ondas de choque. Luego del tratamiento esta situación se revirtió y 69,5 por ciento de los enfermos dejaron de sentirlo. Según la escala de Harris, 50 por ciento de los pacientes estudiados tuvo una interpretación cualitativa de pobre (<70 puntos) antes de iniciar el tratamiento; posteriormente, solo 8,6 por ciento permanecieron con esa puntuación. Conclusiones: La terapia con las ondas de choque es una técnica no invasiva, segura y eficaz. Posibilitó una rápida recuperación de los pacientes atendidos y su incorporación a las actividades diarias(AU)

ABSTRACT Introduction: Shock wave therapy is acoustic waves present in daily situations. This method is currently used to treat trochanteric bursitis. Objective: To evaluate the effectiveness of shockwave therapy in the treatment of trochanteric bursitis. Methods: A descriptive, cross-sectional study was conducted with 46 patients diagnosed with trochanteric bursitis. They were treated with Piezolith-3000 equipment (extracorporeal shock waves) at Frank País International Orthopedic Scientific Complex, from March 2014 to April 2018. The analysis of the variables (age, sex, pain and Harris scale) was performed. The absolute and relative frequencies were obtained. Tables and graphs were prepared to summarize the statistical information of the investigation. Results: There was a predominance of the female sex (86.9 percent) and the age group of 46-55 years (50 percent). All patients had pain before receiving shock waves. After treatment this situation was reversed; the pain stopped in 69.5 percent of the patients. According to Harris scale, 50 percent of the patients studied had a poor qualitative interpretation (<70 points) before starting treatment; subsequently, only 8.6 percent remained at that score. Conclusions: Shockwave therapy is a non-invasive, safe and effective technique. It enabled a rapid recovery of patients and their return into daily activities(AU)

RÉSUMÉ Introduction: Les ondes de choc extracorporelles sont des ondes acoustiques présentes dans des situations de la vie quotidienne. C'est une technique actuellement utilisée pour traiter la bursite trochantérienne. Objectif: Évaluer l'efficacité de la thérapie par ondes de choc dans le traitement de la bursite trochantérienne. Méthodes: Une étude transversale descriptive de 46 patients diagnostiqués de bursite trochantérienne, et traités par ondes de choc extracorporelles à l'aide de l'appareil Piezolith-3000, a été réalisée dans le Complexe scientifique international d'orthopédie « Frank Pais¼, pendant la période de mars 2014 et avril 2018. On a effectué une analyse des variables (âge, sexe, douleur, score de Harris). On a obtenu les fréquences absolues et relatives, et grâce à elles, on a élaboré les tableaux et graphiques abrégeant l'information statistique de la recherche. Résultats: Le sexe féminin (86.9 pourcent) et la tranche d'âge de 46-55 ans (50 pourcent ) ont prédominé. Tous les patients soufraient de douleur avant l'application des ondes de choc. Après le traitement, cette situation s'est inversée, et 69.5 pourcent des malades ont cessé de la ressentir. D'après le score de Harris, les résultats obtenus dans 50 pourcent des patients ont été considérés comme mauvais (<70 points) avant le commencement du traitement ; puis après, seulement 8.6 pourcent des patients ont conservé cette évaluation. Conclusions: La thérapie par ondes de choc extracorporelles est donc une technique non invasive, fiable et efficace. Elle a permis la récupération des patients et leur retour aux activités de la vie quotidienne(AU)

Uso da terapia por ondas de choque para o tratamento do linfedema associado ao câncer de mama: uma revisão sistemática / Use of shockwave therapy for the treatment of lymphedema associated to breast cancer: a systematic review

O linfedema associado ao câncer de mama é causa de prejuízo significativo da qualidade de vida deste grupo de pacientes e constitui complicação frequente das intervenções necessárias nesse tipo de câncer. Sabe-se que o tratamento utilizado no linfedema associado ao câncer de mama envolve a Terapia Física Complexa (TFC), cuja eficácia é limitada e não atua diretamente na patogênese dessa comorbidade. Conforme já demonstrado em alguns estudos, o uso da Terapia por Ondas de Choque (TOC) demonstra-se potencialmente benéfico para reduzir o linfedema pela indução de neoangiogênese e linfangiogênese. Objetivo: Avaliar o impacto da TOC no tratamento do linfedema associado ao câncer de mama comparado ao uso da TFC. Métodos: Foram utilizadas as seguintes bases de dados: PubMed/MedLine; BIREME; LILACS; The Cochrane Library e EMBASE, e através de busca manual de artigos. Adotou-se o método de pesquisa PICO e os descritores MeSH ajustados conforme a respectiva base de dados. Resultados: Foram encontrados um total de 262 artigos e selecionados por leitura do título ou resumo um total de 17 estudos. Seis foram excluídos por serem duplicatas, totalizando 11 artigos eleitos para verificação dos critérios de inclusão. Destes, nenhum artigo atendeu ao delineamento da metodologia proposta para esta revisão. Três deles se destacaram por se aproximarem mais da temática proposta e foram discutidos. Conclusão: É necessária a realização de estudos com qualidade metodológica adequada para avaliar o potencial benefício do uso da TOC, visando contribuir para a composição de um tratamento mais eficaz, seguro e que atue na patogênese da doença.

Lymphedema associated with breast cancer is a cause of significant impairment of the quality of life and is a frequent complication of the necessary interventions in this type of cancer. It is known that the treatment used in lymphedema associated with breast cancer involves Complex Physical Therapy (CPT), whose efficacy is limited and does not act directly in the pathogenesis of this comorbidity. As demonstrated in some studies, the use of Shock Wave Therapy (TSWT) is potentially beneficial in reducing lymphedema by inducing neoangiogenesis and lymphangiogenesis. Objective: To evaluate the impact of TSWT on the treatment of lymphedema associated with breast cancer compared to the use of CPT. Methods: The following databases were used: PubMed / MedLine; BIREME; LILACS; The Cochrane Library and EMBASE, and through manual article search. We adopted the PICO search method and the Mesh descriptors were adjusted according to the respective database. Results: A total of 262 articles were found and selected by reading the title or abstract a total of 17 studies. Six were excluded because they were duplicates, totaling 11 articles elected to verify the inclusion criteria. Of these, no article met the outline of the methodology proposed. Three of them were closer to the proposed theme and were discussed. Conclusion: It is necessary to carry out studies with adequate methodological quality to evaluate the potential benefit of the use of TSWT, in order to contribute to the composition of a more effective and safe treatment, that acts in the pathogenesis of the disease.

Terapia de ondas de choque frente a infiltración corticosteroidea en el tratamiento de la fascitis plantar crónica / Extracorporeal shockwave therapy versus corticosteroid injection in chronic plantar fasciitis

Introducción La fascitis plantar crónica (FPC) es una afección dolorosa, en la cual el objetivo principal del tratamiento es aliviar el dolor y restaurar la función. La terapia de ondas de choque (TOCH) ha demostrado eficacia en el tratamiento de la fascitis plantar con pocos efectos secundarios en comparación con otros métodos conservadores. El objetivo del estudio es comparar la respuesta al tratamiento de TOCH frente a la infiltración con corticosteroides en el tratamiento de la fascitis plantar crónica. Materiales y métodos Sesenta pacientes con FPC fueron distribuidos de forma aleatoria para recibir TOCH (grupo A, n=36) o infiltración con corticosteroides (grupo B, n=24) a través de un programa de generación aleatorizada. Fueron evaluados con EVA y AOFAS para el retropié antes del tratamiento, inmediatamente después del tratamiento, a los 3, 6 y 12 meses posteriores al tratamiento. Resultados Los dos grupos fueron similares en características demográficas. Ambos grupos mejoraron durante el tratamiento y el período de seguimiento. La media de EVA disminuyó de 8 a 1,68 (p <0,001) en el grupo A y de 6,75 a 1,31 (p <0,001) en el grupo B. En el AOFAS presentó un incremento medio de 50,3 a 67,8 (p <0,001) en el grupo A y de 51,3 a 66 (p <0,001) en el grupo B a los 12 meses de seguimiento. A los 3 meses, el grupo B presentó una puntuación media de EVA más baja que en el grupo A (1,12 frente a 1,96; p=0,035), pero al final del seguimiento se observó mejoría en ambos grupos. Discusión Las infiltraciones con corticosteroideas y TOCH son efectivas en la reducción de síntomas y el incremento de la funcionalidad de los pacientes diagnosticados de FPC. Nivel de evidencia clínica Nivel II.

Background Chronic plantar fasciitis (CPF) is a painful condition where the primary goal of treatment is relieve the pain and restore function. Extracorporeal shockwaves therapy (ESWT) has shown efficacy in the treatment of plantar fasciitis with reported few side effects compared to other conservative methods. The purpose of the study is to compare the response to treatment of ESWT against corticosteroid infiltration for PF using VAS (Visual Analogue Scale) and AOFAS (American Orthopedic Foot and Ankle Society's) hind foot scales. Materials & methods Sixty patients with PF were randomized to receive ESWT (group A, n=36) or corticosteroid infiltration (group B, n=24) through a program of random number generation. They were evaluated with VAS and AOFAS hind foot scales before treatment, immediately after treatment and at 3, 6 and 12 months post treatment. Results The two groups were similar in demographic characteristics. Both groups improved during treatment and follow-up period. The mean VAS decreased from 8 to 1.68 (p <0.001) in group A and 6.75 to 1.31 (p <0.001) in group B and presented a mean increase in AOFAS scale from 50.3 to 67.8 (p <0.001) in group A and 51.3 to 66 (p <0.001) in group B at 12 months follow up. At 3 months, the B group presented a lower average score in VAS when compared with patients in group A (1.12 vs 1.96; p=0.035). Finally, follow-up improvement was seen in both groups with no significant differences. Discussion ESWT and corticosteroid injections are both effective in reducing symptoms and increased functionality when applied to patients diagnosed with CPF. Evidence level II.

Ondas de choque de baja intensidad como alternativa terapéutica de la disfunción eréctil: experiencia inicial en el Hospital Italiano de Buenos Aires y revisión de la bibliografía / Low Intensity Shock Waves as a Therapeutic Alternative for Erectile Dysfunction: Initial Experience at the Hospital Italiano de Buenos Aires and Review of The Literature

Objetivos: los inhibidores de fosfodiesterasa revolucionaron el tratamiento de la disfunción eréctil. Las ondas de choque de baja intensidad emergen como una alternativa terapéutica no invasiva. Materiales y métodos: estudio de cohorte prospectiva y observacional, en el que se evaluó la respuesta de 17 pacientes sexualmente activos al tratamiento con ondas de choque de baja intensidad a los 3 y 6 meses, mediante el Indice Internacional de Función Eréctil (IIEF-6), las preguntas 2 y 3 del Sexual Encounter Profile (SEP-2 y SEP-3), y el Erection Hardness Score (EHS) para evaluar la rigidez peneana, así como una evaluación de satisfacción global con el tratamiento (GAQ) y de recomendación del mismo. Resultados: 6 pacientes presentaban disfunción eréctil leve y 11 disfunción eréctil moderada-severa. Ambos grupos mostraron diferencias estadísticamente significativas en el IIEF-6, SEP-2, SEP-3 y EHS, a los 3 y 6 meses. Sin embargo, no todos los pacientes se mostraron satisfechos o recomendarían el tratamiento, sobre todo en aquellos con disfunción eréctil moderada-severa previo al tratamiento. Conclusión: las ondas de choque de baja intensidad son un tratamiento emergente para la disfunción eréctil, aunque aun sin evidencia clara de su eficacia e indicaciones. Los dispares resultados de los grupos se han debido probablemente a la heterogeneidad de las condiciones basales de los pacientes.(AU)

Objectives: Iphosphodiesterase inhibitors revolutionized the treatment of erectile dysfunction. Low intensity shockwave therapy emerge as a non-invasive therapeutic alternative. Materials and methods: this was a prospective and observational study, in which 17 sexually active patients were evaluated 3 and 6 months after treatment with low intensity shockwave therapy, using the International Index of Erectile Function (IIEF-6), questions 2 and 3 of the Sexual Encounter Profile (SEP-2 and SEP-3), and the Erection Hardness Score (EHS) to assess penile rigidity, as well as a global satisfaction evaluation with the treatment (GAQ) and if they would recommend it to others. Results: 6 patients showed mild erectile dysfunction and 11 moderatesevere erectile dysfunction. Both groups showed statistically significant differences in IIEF-6, SEP-2, SEP-3 and EHS, after 3 and 6 months. However, not all of them were satisfied with the treatment or would recommend it to others, especially those with moderate-severe basal erectile dysfunction. Conclusion: low intensity shockwave therapy is an emergent treatment for erectile dysfunction, although there is no sufficient evidence of its efficacy and indications. The differences between groups were due probably to the heterogeneity of the basal conditions of the patients.(AU)

Terapia de ondas de choque focal para osteoartrose de joelho: um ensaio clínico randomizado duplo-cego / Focused extracorporeal shockwave therapy (f-ESWT) for knee osteoarthritis: a double-blind randomized clinical trial

Objetivo: Avaliar eficácia da terapia de ondas de choque focal (f-ESWT) comparada ao placebo para dor e incapacidade em pacientes com osteoartrose de joelho (OA). Métodos: Ensaio clínico randomizado, duplo-cego, placebo controlado, pacientes com OA primária de joelhos realizaram exercícios (alongamentos de isquiotibiais e fortalecimento de quadríceps) e randomizados em f-ESWT ou placebo. Todos os pacientes foram submetidos a 4 sessões semanais de 7.000 pulsos, e no grupo f-ESWT a energia foi de até 0.15mJ/mm2. O desfecho primário foi a escala analógica visual (VAS) para dor em 1 mês. Os desfechos secundários foram WOMAC, TUG, Lequesne e índice de resposta OMERACT-OARSI em 1 e 3 meses; bem como VAS aos 3 meses e eventos adversos (EAs). O teste de Mann-Whitney U e o teste exato Fisher foram utilizados com alfa = 5% e poder = 80% em uma análise de intenção de tratar. Os desfechos contínuos foram relatados como média ± desvio padrão. Resultados: 18 pacientes (9 em cada grupo), idade de 60.6±8.7 com 33.3% homens. Não houve diferença significativa entre grupos em qualquer variável. F-ESWT não foi superior ao placebo em 1 mês: VAS = -2,97 ± 3,18 e -2,68 ± 2,33 cm, respectivamente, p = 0,96. Somente o TUG no 1º mês foi significativo: 9.09 ± 2.30 e 11.01 ± 2.85 seg, p = 0.01. Conclusão: f-ESWT não foi superior ao placebo para osteoartrose de joelhos. Este estudo foi insuficiente para detectar diferenças. Novos estudos devem usar WOMAC A (subescala dor) como desfecho primário e recrutar 92 pacientes.

Objective: To assess the efficacy of focused extracorporeal shockwave therapy (f-ESWT) when compared to placebo for pain and disability in patients with knee osteoarthritis (OA). Methods: Randomized, parallel, double-blind, placebo-controlled clinical trial. Patients with primary knee OA were given a set of exercises (hamstring stretching and quadriceps strengthening) and randomized into f-ESWT or placebo (sham probe). All patients were submitted to 4 weekly sessions of 7,000 pulses, and in the f-ESWT group energy was up to 0.15mJ/mm2. Primary outcome was visual analog scale (VAS) for pain at 1 month. Secondary outcomes were WOMAC, TUG, Lequesne's index and OMERACT-OARSI responder index at 1 and 3 months; as well as VAS at 3 months and adverse events (AEs). Both patients and outcome assessors were blinded. Mann-Whitney U test and Fisher's exact test were used with alpha=5% and power=80% in an intention-to-treat analysis. Continuous outcomes were reported as mean± standard deviation. Results: 18 patients were included (9 in each group), aging 60.6±8.7, with 33.3% males. There was no significant difference at baseline across groups in any variables. f-ESWT was not superior to placebo at 1 month: VAS=-2.97±3.18 and -2.68±2.33cm, respectively, p=0.96. TUG at 1 month had significant differences: 9.09±2.30 and 11.01±2.85sec, p=0.01. No serious AEs were observed. Conclusions: f-ESWT was not superior to placebo for knee OA. This RCT was underpowered to detect differences in this study. New RCTs should use WOMAC A (pain subscale) as primary outcome and recruit at least 92 patients.