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1.
Psychon Bull Rev ; 2024 Sep 23.
Article in English | MEDLINE | ID: mdl-39313676

ABSTRACT

Monitoring the environment for prospective memory (PM) targets can be attentionally demanding, such as searching for a pharmacy to pick up medication while driving in traffic. It is therefore optimal to increase monitoring in contexts when the probability of encountering a PM target is high (e.g., business plaza) and decrease monitoring in contexts when the probability is low (e.g., residential area), referred to as strategic monitoring. In some instances, though, identifying whether the context is appropriate for monitoring can be attentionally demanding. For example, when contextual information varies unpredictably, it may be easier to continuously monitor rather than dynamically increase and decrease monitoring on a moment-by-moment basis. The current study extends previous research by showing that participants strategically monitor when the ongoing task automatically orients attention to contextual information (i.e., focal context cues), regardless of the difficulty of checking for PM targets (Experiment 1). In contrast, when ongoing task processing does not orient attention to contextual information (i.e., nonfocal context cues), participants only strategically monitor when the demands of target checking are high (Experiment 2). These findings suggest that the decision to utilize context to adjust monitoring is driven by a cost-benefit analysis that weighs the perceived efforts of context identification relative to the expected benefit of not having to check for PM targets on half of the trials. When the perceived effort of identifying context on each trial is outweighed by the benefit of reducing target checking on a subset of trials, strategic monitoring occurs.

2.
Cogn Res Princ Implic ; 9(1): 63, 2024 Sep 18.
Article in English | MEDLINE | ID: mdl-39289316

ABSTRACT

People perform poorly at sighting missing and wanted persons in simulated searches due to attention and face recognition failures. We manipulated participants' expectations of encountering a target person and the within-person variability of the targets' photographs studied in a laboratory-based and a field-based prospective person memory task. We hypothesized that within-person variability and expectations of encounter would impact prospective person memory performance, and that expectations would interact with within-person variability to mitigate the effect of variability. Surprisingly, low within-person variability resulted in better performance on the search task than high within-person variability in Experiment one possibly due to the study-test images being rated as more similar in the low variability condition. We found the expected effect of high variability producing more hits for the target whose study-test images were equally similar across variability conditions. There was no effect of variability in Experiment two. Expectations affected performance only in the field-based study (Experiment two), possibly because performance is typically poor in field-based studies. Our research demonstrates some nuance to the effect of within-person variability on search performance and extends existing research demonstrating expectations affect search performance.


Subject(s)
Facial Recognition , Memory, Episodic , Humans , Facial Recognition/physiology , Male , Female , Adult , Young Adult , Attention/physiology , Adolescent
3.
Cureus ; 16(8): e67454, 2024 Aug.
Article in English | MEDLINE | ID: mdl-39314589

ABSTRACT

Introduction Elderly people may experience a deterioration in cognitive function as part of natural aging, which impacts their ability to function independently. Dementia is often experienced by the elderly; their cognitive and memory deficits can limit independence and productivity. Metacognitive skills training can facilitate self-awareness and strategy use and may improve cognitive skills.  Aims and objectives  The article aimed to evaluate the effectiveness of prospective memory and metacognitive skills training in improving cognitive skills and quality of life for elderly persons with dementia.  Methods This was a quasi-experimental study that took place in Chennai city, India. Based on the criteria, a total of fifty (n = 50) elderly participants were selected and divided into control (n = 25) and experimental (n = 25) groups. The control group underwent conventional occupational therapy, whereas the experimental group underwent prospective memory and metacognitive skills training (PM and MST) over 36 sessions (three times/week, for 12 weeks). Outcome measures used were the mini mental status examination (MMSE) and quality of life - Alzheimer's disease (QOL-AD). Data were analyzed using the Mann-Whitney U test and Wilcoxon signed-rank test.  Results The results revealed that there were statistically significant (p-value < 0.05) differences between control and experimental groups. When compared to the control group, the experimental group had greater significant improvement in cognitive skills (MMSE, the control group's mean score was 20.94 and the experimental group's mean score was 30.94, p-value = 0.026), and quality of life (QOL-AD, the control group's mean score was 13.54 and the experimental group's mean score was 37.46, p-value = 0.000) after the implementation of a 12-week therapy program.  Conclusion This study concludes that PM and MST can be used as an effective intervention as it improves cognitive skills and quality of life among elderly persons with dementia.

4.
Article in English | MEDLINE | ID: mdl-39237071

ABSTRACT

OBJECTIVES: To examine the association between subjective and objective prospective memory (PM) in people with multiple sclerosis (PwMS). DESIGN: Secondary analysis of a cross-sectional cohort study. SETTING: Community-based comprehensive MS center. PARTICIPANTS: PwMS (n = 112) who completed a battery that included measures of PM, depression, and fatigue. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Objective PM was measured with the performance-based Memory for Intentions Test (MIST), while subjective PM was assessed with the self-report Perceived Deficits Questionnaire-Prospective Memory (PDQ-PM). RESULTS: PwMS had low scores on the PDDS (Median = 2) and HADS-D (M = 5.29), with 26.8% scoring one standard deviation or lower (≤ 15th percentile) on the MIST. Objective PM was significantly associated with subjective PM in a multivariate model (ß = -0.18, p = .036), which accounted for demographics, physical disability, retrospective memory, and depressive and fatigue severity. Physical disability, depression, and fatigue were also significant contributors to subjective PM. Time-based PM performance emerged as the specific component that was associated with subjective PM. CONCLUSIONS: These findings suggest that among PwMS with relatively mild impairment and symptomatology, their objective PM performance was associated with their self-assessments, even when considering retrospective memory and factors that influence their cognitive perceptions. The results expand upon the subjective-objective cognition discrepancy literature in MS and highlights how the PDQ-PM could be used as a complementary measure to help identify difficulties with PM.

5.
J Neuropsychol ; 2024 Aug 27.
Article in English | MEDLINE | ID: mdl-39188167

ABSTRACT

A large body of evidence suggests that individuals with traumatic brain injury (TBI) have significant difficulties with prospective memory (PM), the memory for future intentions. However, the processes underlying this cognitive deficit remain unclear. This study aimed to gather further evidence regarding PM functions in TBI and clarify the role of neuropsychological deficits, metamemory, and mood disorders. We used a laboratory-based clinical measure, the Virtual Week, to examine PM function in 18 patients with TBI and 18 healthy control subjects. Measures of attention, processing speed, executive functions, episodic memory, and self-report questionnaires were also administered. In line with prior literature, our findings indicate that individuals with TBI had a consistent deficit compared to controls across all PM tasks. In previous studies, TBI patients had more severe impairment on time-based tasks; nevertheless, our results show that across all participants event-based tasks were easier to perform compared to time-based only when the retrospective memory demand was high. The patients were not only impaired on the prospective component of PM but also failed to recognise the content of their task (the retrospective component). Interestingly, the TBI group did not report higher levels of everyday memory problems, anxiety and depression compared to the control group. These measures also failed to correlate with PM and recognition memory performance. This study found that besides the neuropsychological deficits, a global impairment in PM functioning is present in individuals with TBI across various task types, tasks low and high in retrospective demands, and event versus time-based.

6.
J Cogn ; 7(1): 56, 2024.
Article in English | MEDLINE | ID: mdl-39035074

ABSTRACT

Several studies have suggested that time monitoring is important for appropriate time-based prospective memory (TBPM). However, it is still unknown if people actively use internal timing processes to monitor the approaching target time, and whether they do so by tracking the duration between clock digits, or by counting and matching the numerical progression of clock ticks' digits with the target time. Therefore, in the present study, we investigated whether a manipulation of the external time affected time monitoring and TBPM performance. In two experiments, participants performed two identical TBPM tasks: a first TBPM block with no clock-speed manipulation followed by a second TBPM block, where the clock-speed was manipulated as faster or slower (experimental conditions) or normal (control condition). The results showed that only participants in the slower clock condition increased time monitoring in the second compared to the first TBPM block (d = 0.42 and 1.70); moreover, particularly in Experiment 2, participants in the faster clock condition checked the clock significantly less frequently than participants in the slower clock (d = -1.70) and in the control condition (d = -0.98), but only during the 4th minute. No effect was found for TBPM performance. Overall, results suggested that people tracked the target time by counting and matching the numerical progression of clock ticks' digits with the target time. The findings are discussed considering the most recent theoretical advancements about the relationship between time perception and TBPM.

7.
Geriatr Psychol Neuropsychiatr Vieil ; 22(2): 217-231, 2024 Jun 01.
Article in French | MEDLINE | ID: mdl-39023157

ABSTRACT

Prospective memory allows us to remember to perform an action in the future in response to environmental cues (event-based) or predetermined times (time-based). It is often impaired in individuals with mild cognitive impairment. These deficits are related to various cognitive functions such as episodic memory and executive functions and are particularly affected in pathological ageing. In this article, we propose a literature review of non-pharmacological interventions with the elderly with MCI and neurodegenerative diseases. This article explores different strategies for managing prospective memory, including cognitive training, mnemonic strategies, and external aids. In all cases, it is important to design personalized interventions that take account of patients' individual characteristics. Research into the long-term effectiveness of these strategies is still limited, and further studies are needed to properly assess their benefits.


Subject(s)
Aging , Cognitive Dysfunction , Memory Disorders , Memory, Episodic , Humans , Aged , Aging/psychology , Memory Disorders/rehabilitation , Memory Disorders/psychology , Cognitive Dysfunction/rehabilitation , Cognitive Dysfunction/psychology , Aged, 80 and over , Male , Female
8.
Q J Exp Psychol (Hove) ; : 17470218241270264, 2024 Aug 23.
Article in English | MEDLINE | ID: mdl-39075805

ABSTRACT

Remembering to complete goals-termed prospective memory (PM)-is critical for success in everyday life, yet minimal empirical work has been dedicated to examining PM within an educational setting. The main goal of this study was to investigate students' ability to complete numerous future-oriented academic intentions (PM tasks) while simultaneously paying attention to a lecture and to see if working memory (WM) capacity and adding subtle contextual information would support the students' likelihood of completing their PM tasks. Participants took part in a 2-hr session of college course-like activities. Throughout the session, there was occasionally the opportunity to complete one of several naturalistic PM tasks. The following findings are based on the results of our Bayesian models. Providing subtle contextual clues about when PM tasks could be completed was found to likely increase performance. The number of PM intentions to be remembered (i.e., load) produced no discernable effect on ongoing task performance or PM performance. Furthermore, individual differences in WM capacity were likely to be predictive of a near-zero change in PM performance. The current findings hold meaningful implications for educators, wherein providing context, even at a subtle level, can enhance students' ability to remember to complete tasks, without altering their ability to focus on the tasks at hand. Moreover, it appears that asking students to remember to complete multiple, prospective in-class tasks is not likely to hinder task completion or their ability to focus on other ongoing tasks.

9.
Memory ; 32(7): 947-957, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38968418

ABSTRACT

The current study examined the effect of a delay on naturalistic time-based prospective memory (PM) tasks. Two experiments were performed to compare PM performance on a texting task with delays of 1 to 6 days after an initial session. In the first experiment, half of the participants were asked to repeat their response with the same delay to test whether requiring a second response (i.e., a repeated PM task, such as taking medication at the same time each day) would affect time-based PM performance. In the second experiment, participants were given an implicit or an explicit reminder several hours before their time to respond to examine the effect of type of reminder on this PM task. The results of both experiments showed a significant decline in PM performance between the 1-day and multi-day delays. Repeating responses (Experiment 1) had no effect on accuracy of the PM task, but in Experiment 2, explicit experimenter-initiated reminders significantly increased time-based PM performance compared with implicit reminders. These results are discussed in the context of previous studies that have tested delay effects on time-based PM and current theoretical descriptions of time-based PM.


Subject(s)
Memory, Episodic , Humans , Male , Female , Young Adult , Time Factors , Adult , Reaction Time , Adolescent , Text Messaging , Reminder Systems
10.
Mem Cognit ; 2024 Jun 18.
Article in English | MEDLINE | ID: mdl-38888717

ABSTRACT

Interest in the metacognitive aspects of prospective memory (PM) is growing. Yet, the interplay between participants' metacognitive awareness of PM task demands and features that contribute to successful PM require further attention. To this aim, participants in the current study completed laboratory-based PM tasks of varying difficulty (cue focality: focal, nonfocal-category, or nonfocal-syllable) and reported their strategy use and perceptions of PM task importance. Most participants reported using a strategy regardless of cue focality. However, only under the most challenging condition (i.e., nonfocal-syllable) did participants who reported using a strategy exhibit better PM performance compared to those who did not use a strategy. Additionally, strategy use and cue focality were independently associated with greater costs to ongoing task performance: strategy users exhibited greater slowing relative to individuals who did not use a strategy, and the extent of slowing was greater as the task difficulty increased across cue focality. Finally, perceived task importance appeared to play an important role in the interactive link between cue focality and strategy use on PM performance for the more challenging, nonfocal PM tasks. Specifically, moderation analyses suggested that greater perceived task importance alone may improve the likelihood of PM success for moderately challenging PM tasks (i.e., nonfocal-category), but for the most challenging PM tasks (i.e., nonfocal-syllable), individuals' strategy use was still associated with better PM performance. The present study expands our understanding of metacognition's role in PM performance and has implications for everyday PM performance.

11.
Article in English | MEDLINE | ID: mdl-38915139

ABSTRACT

OBJECTIVE: To accurately assess prospective memory (PM) functioning in patients who sustained a traumatic brain injury (TBI), it is important to use both subjective (questionnaires) and objective (tests) measures. However, which factors have the most significant effect on each PM measure remains unknown. This observational study aims to verify whether TBI severity or psychological status has the most influence on patients' objective and subjective PM measures. METHOD: Fifteen healthy control (HC) participants (n = 15), 19 patients with a mild TBI (n = 19) and 30 patients with a moderate-to-severe TBI (n = 30) were recruited during the post-acute phase. For almost every participant, a relative was also recruited (n = 62). The Test écologique de mémoire prospective (TEMP), an objective computerized PM measure consisting of naturalistic stimuli, was administered to all participants along with anxiety (BAI) and depression inventories (BDI). Participants and their relatives also completed a questionnaire, the comprehensive assessment of PM (CAPM), a subjective PM measure assessing everyday failures. RESULTS: Results on the objective PM measure were predicted by TBI severity, while psychological symptoms (BAI and BDI) predicted scores on the subjective PM measure. In addition, relatives in the moderate-to-severe TBI group reported more PM failures on the subjective measure and their perception was significantly correlated with results on the objective PM measure, which was not the case for the other two groups of relatives. CONCLUSIONS: Objective PM measures are related to TBI severity and appear more robust against the influence of psychological factors than subjective PM measures.

12.
Sensors (Basel) ; 24(11)2024 Jun 03.
Article in English | MEDLINE | ID: mdl-38894403

ABSTRACT

OBJECTIVE: To investigate the activity-based prospective memory performance in patients with insomnia, divided, on the basis of actigraphic evaluation, into sleep onset, maintenance, mixed and negative misperception insomnia. METHODS: A total of 153 patients with insomnia (I, 83 females, mean age + SD = 41.37 + 16.19 years) and 121 healthy controls (HC, 78 females, mean age + SD = 36.99 + 14.91 years) wore an actigraph for one week. Insomnia was classified into sleep onset insomnia (SOI), maintenance insomnia (MaI), mixed insomnia (MixI) and negative misperception insomnia (NMI). To study their activity-based prospective memory performance, all the participants were required to push the actigraph event marker button twice, at bedtime (task 1) and at get-up time (task 2). RESULTS: Only patients with maintenance and mixed insomnia had a significantly lower accuracy in the activity-based prospective memory task at get-up time compared with the healthy controls. CONCLUSION: The results show that maintenance and mixed insomnia involve an impaired activity-based prospective memory performance, while sleep onset and negative misperception insomnia do not seem to be affected. This pattern of results suggests that the fragmentation of sleep may play a role in activity-based prospective memory efficiency at wake-up in the morning.


Subject(s)
Actigraphy , Memory, Episodic , Sleep Initiation and Maintenance Disorders , Humans , Female , Sleep Initiation and Maintenance Disorders/physiopathology , Male , Adult , Middle Aged , Actigraphy/methods , Sleep/physiology
13.
Mult Scler Relat Disord ; 88: 105718, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38878624

ABSTRACT

BACKGROUND: Persons with multiple sclerosis (PwMS) can experience deficits in prospective memory (PM) or "remembering to remember," which are associated with functional difficulties. However, no cognitive rehabilitation intervention has specifically addressed improving PM in PwMS. The Telehealth PM Intervention (TPMI) provides a novel combination of two strategies-visual imagery and implementation intentions-that have each been beneficial in other populations. This study aimed to evaluate the feasibility of TPMI and its preliminary efficacy, which could be used to inform future trials. METHODS: Participants (n = 35) were PwMS who were pre-screened and endorsed experiencing problems "remembering places they have to be" and "things they have to do." After completing a baseline evaluation, which included objective (Memory for Intentions Test; MIST) and subjective (Perceived Deficits Questionnaire; PDQ-PM) measures of PM, participants were randomized to either the active treatment (TPMI; n = 17) or active control group (Control; n = 18). TPMI was offered through remote one-on-one sessions twice a week over a four-week period. Participants were asked about treatment credibility and expectancy during the first session. The MIST and PDQ-PM were repeated at post-treatment, where treatment satisfaction was also captured. Mann-Whitney U and chi-square tests were used to examine the feasibility measures, while repeated measures ANOVAs were used to examine changes in the PM outcomes. RESULTS: A total of 88.2 % of the TPMI group completed all eight sessions, with moderate-to-high (≥7 out of 10) treatment credibility/expectancy and satisfaction reported by 93.3 % and 86.7 %, respectively. While there were no significant effects on overall PM, the TPMI group had an improvement in objective time-based PM after adjusting for baseline differences (F(1,29) = 4.61, p = 0.040; d = 0.80). Furthermore, the TPMI group had a significant reduction in the number of time-based loss of content errors compared to the Control group, which remained significant after covariate adjustment (F(1,25) = 4.29, p = 0.049; d = 0.83). CONCLUSIONS: TPMI is a feasible intervention, with high completion rates and moderate-to-high treatment ratings, that can be delivered remotely. Early evidence shows its potential benefit for improving time-based PM, a particular concern for PwMS, which should be further evaluated in a larger clinical trial.


Subject(s)
Feasibility Studies , Memory Disorders , Memory, Episodic , Multiple Sclerosis , Telemedicine , Humans , Male , Female , Multiple Sclerosis/rehabilitation , Multiple Sclerosis/therapy , Multiple Sclerosis/complications , Middle Aged , Adult , Memory Disorders/etiology , Memory Disorders/rehabilitation , Memory Disorders/therapy , Patient Satisfaction
14.
BMC Psychol ; 12(1): 318, 2024 May 31.
Article in English | MEDLINE | ID: mdl-38816781

ABSTRACT

BACKGROUND: Prospective memory (PM) refers to the ability to perform planned activities in the appropriate future situations. It needs to be planned in advance and processed through multiple stages such as encoding, retention, retrieval, and execution, which usually require more attention resources. Impulsivity trait individuals are usually characterized by lack of consideration, premature expression, excessive risk-taking and easy to make inappropriate reaction, so they are more likely to show disadvantages in PM. Nevertheless, increasing the importance of PM tasks can promote more adequate and effective cue encoding, and encourage individuals to devote attention to PM tasks, which may change the disadvantage of impulsivity individuals in PM performance. METHODS: In this study, the between-subjects design of 2 (trait type: high-impulsivity trait, low-impulsivity trait) ×2 (task importance: important, unimportant) was adopted in the experiment, the 2-back task was used for the ongoing task, and the focal cues were used for the PM task cues. RESULTS: The results showed that the PM accuracy of high-impulsivity trait individuals was lower than that of low-impulsivity trait individuals under the task unimportant condition, but there was no difference between the two traits groups under the task important condition. CONCLUSIONS: The results of this study suggested that high-impulsivity trait individuals had a deficit in PM performance, but emphasizing the importance of PM tasks can compensate for their disadvantage in PM performance.


Subject(s)
Impulsive Behavior , Memory, Episodic , Personality , Humans , Male , Female , Young Adult , Adult , Cues , Attention
15.
Front Psychol ; 15: 1279144, 2024.
Article in English | MEDLINE | ID: mdl-38699576

ABSTRACT

Background: Prospective memory (PM) is the ability to remember to perform an intended action at a specific future moment. The current study examined the impact of age, task focality, and cue salience on PM in children aged 2 to 6 years, based on the multiprocess theory of PM and the executive framework of PM development. Additionally, the study explored the relationship between various cognitive abilities and their association with PM performance. Methods: A total of 224 preschool-aged children, aged 2-6, engaged in event-based PM tasks with varying cognitive demands. The tasks were either focal or nonfocal, with salient or nonsalient cues. Additionally, individual differences in cognitive abilities were measured. Results: The results support previous indications that even very young children can successfully complete event-based PM tasks. The accuracy of PM display improved with age, especially between the ages of 3 and 4. Better performance was observed in focal PM tasks compared to nonfocal PM tasks. Additionally, preschoolers' PM performance correlated with various cognitive abilities, including fluid intelligence, retrospective memory, inhibitory control, working memory, and language ability. These correlations varied depending on the child's age and the task's nature. For both focal and nonfocal PM tasks, cognitive abilities partially mediated the relationship between age and PM performance. Conclusion: In summary, this study comprehensively explores the specific roles played by age and fundamental cognitive abilities in event-based PM performance among preschool-aged children.

16.
Autism Res ; 17(6): 1258-1275, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38800974

ABSTRACT

Prospective memory (PM) is the ability to remember to carry out intended actions in the future. The present study investigated the effects of episodic future thinking (EFT) and enactment encoding (EE) on PM performance in autistic adults (ASD). A total of 72 autistic individuals and 70 controls matched for age, gender, and cognitive abilities completed a computerized version of the Dresden breakfast Task, which required participants to prepare breakfast following a set of rules and time restrictions. A two (group: ASD vs. controls) by three (encoding condition: EFT vs. EE vs. standard) between-subjects design was applied. Participants were either instructed to engage in EFT or EE to prepare to the different tasks prior to performing the Dresden breakfast or received standard instructions. Analyses of variance were conducted. Autism-spectrum-disorders (ASD) participants did not differ from control participants in their PM performance, regardless of which strategy they used. Compared to the standard condition, EE but not EFT improved time-based PM performance in all participants. This is the first study to find spared time-based PM performance in autistic individuals. The results confirm earlier results of beneficial effects of EE on PM performance. Findings are discussed with regards to the methodology used, sample composition as well as autistic characteristics.


Subject(s)
Autism Spectrum Disorder , Memory, Episodic , Thinking , Humans , Male , Female , Autism Spectrum Disorder/physiopathology , Autism Spectrum Disorder/psychology , Adult , Thinking/physiology , Young Adult , Practice, Psychological , Adolescent , Neuropsychological Tests/statistics & numerical data
17.
J Clin Exp Neuropsychol ; 46(4): 329-340, 2024 May.
Article in English | MEDLINE | ID: mdl-38695493

ABSTRACT

INTRODUCTION: Prospective memory (PM) deficits have been documented in multiple sclerosis (MS). This study aimed to explore the specific types of errors made by persons with MS (PwMS), including differences between PwMS and healthy controls (HC) and PwMS who do and do not have impairments in processing speed and/or verbal learning and memory. METHOD: PwMS (n = 111) and HC (n = 75) completed the Memory for Intentions Test (MIST), an objective measure of PM that has five types of errors that can be coded (PM failure, task substitution, loss of content, loss of time, and random errors). The number and types of PM errors were calculated for the overall MIST and six subscales, which break down performance by types of delay (2-Minute and 15-Minute), cue (Time and Event), and response (Verbal and Action). Impairment was defined as performing < 1.5 SD on either the Symbol Digit Modalities Test (SDMT) or Rey Auditory Verbal Learning Test (RAVLT). Bivariate analyses were used to examine group differences, with post-hoc pairwise comparisons with Bonferroni corrections. RESULTS: Nearly 93% of PwMS made at least one PM error, compared to 76% of HC (V = .24, p = .001). The most commonly made PM error by PwMS was loss of content errors (45.0%). PwMS made significantly more task substitution errors (26.4% vs. 7.6%, p < .001) and fewer loss of time errors (9.5% vs. 21.2%, p < .001) than HC. Impaired PwMS made more errors than non-impaired PwMS, specifically PM failures on time-based tasks. CONCLUSIONS: PM errors are common in PwMS, particularly when there are longer delays and time-based cues. Not only do PwMS make more errors than demographically similar HC, but they exhibit different cognitive process failures.


Subject(s)
Memory Disorders , Memory, Episodic , Multiple Sclerosis , Humans , Male , Female , Adult , Multiple Sclerosis/complications , Multiple Sclerosis/physiopathology , Middle Aged , Memory Disorders/etiology , Memory Disorders/physiopathology , Memory Disorders/diagnosis , Neuropsychological Tests/standards , Verbal Learning/physiology
18.
J Clin Exp Neuropsychol ; 46(4): 352-363, 2024 May.
Article in English | MEDLINE | ID: mdl-38717052

ABSTRACT

OBJECTIVE: Identifying factors that moderate cognitive outcomes following mild traumatic brain injury (mTBI) is crucial. Prospective memory (PM) is a cognitive domain of interest in mTBI recovery as it may be especially sensitive to TBI-related changes. Since studies show that genetic status - particularly possession of the apolipoprotein E (APOE) ε4 allele - can modify PM performance, we investigated associations between mTBI status and APOE-ε4 genotype on PM performance in a well-characterized sample of Veterans with neurotrauma histories. METHODS: 59 Veterans (mTBI = 33, Military Controls [MCs] = 26; age range: 24-50; average years post-injury = 10.41) underwent a structured clinical interview, neuropsychological assessment, and genotyping. The Memory for Intentions Test (MIST) measured PM across multiple subscales. ANCOVAs, adjusting for age and posttraumatic stress symptoms, tested the effects of mTBI status (mTBI vs. MC) and ε4 status (ε4+ vs. ε4-) on MIST scores. RESULTS: Veterans with mTBI history performed more poorly compared to MCs on the MIST 15-min delay (p=.002, ηp2 =.160), Time Cue (p = .003, ηp2 =.157), and PM Total (p = .016, ηp2 =.102). Those with at least one copy of the ε4 allele performed more poorly compared to ε4- Veterans on the MIST 15-min delay (p = .011, ηp2 =.113) and PM Total (p = .048, ηp2 = .071). No significant interactions were observed between mTBI and APOE-ε4 status on MIST outcomes (ps>.25). Within the mTBI group, APOE-ε4+ Veterans performed worse than APOE-ε4- Veterans on the MIST 15-min delay subscale (p = .031, ηp2 = .150). CONCLUSIONS: mTBI history and APOE-ε4 genotype status were independently associated with worse PM performance compared to those without head injury histories or possession of the APOE-e4 genotype. Performance on the MIST 15-min delay was worse in Veterans with both risk factors (mTBI history and APOE-ε4 positivity). Findings suggest that genetic status may modify outcomes even in relatively young Veterans with mTBI histories. Future research examining longitudinal associations and links to neuroimaging and biomarker data are needed.


Subject(s)
Apolipoprotein E4 , Brain Concussion , Memory, Episodic , Veterans , Humans , Male , Apolipoprotein E4/genetics , Adult , Female , Brain Concussion/genetics , Brain Concussion/complications , Brain Concussion/physiopathology , Middle Aged , Young Adult , Genotype , Neuropsychological Tests/statistics & numerical data
19.
J Cogn ; 7(1): 43, 2024.
Article in English | MEDLINE | ID: mdl-38765760

ABSTRACT

While previous research has suggested that prospective memory may be enhanced by providing a social motive (i.e., social importance) or by promising a monetary reward for successful performance, to the best of our knowledge, the underlying mechanisms responsible for these effects are still largely unexplored. In a sample of 96 younger adults, this study investigated how social importance and promising a monetary reward influence the prospective component and the retrospective component of event-based prospective memory separately, with the application of a multinomial modeling approach. Results revealed enhanced prospective memory performance for all importance conditions compared to a standard condition. This improvement was characterized by an increased allocation of resource-demanding attentional processes in performing the prospective memory task at the expense of the ongoing task without an increase in the perceived importance of the prospective memory task. The model-based analyses showed that the beneficial effects of importance arise from an increased engagement of the prospective component, leaving the estimates for the retrospective component unaffected.

20.
Psicol Reflex Crit ; 37(1): 17, 2024 May 06.
Article in English | MEDLINE | ID: mdl-38709384

ABSTRACT

BACKGROUND: Prospective memory is the ability to engage in an intention to be performed in the future. The main objective of this study was to identify instruments that assess both time-based and event-based prospective memory in children and adolescents and that have the potential to be clinically applicable. METHOD: Three databases (PubMed, Scopus, and PsycINFO) were searched to identify existing PM measures in original articles published until 2022. Literature searches were conducted using the following terms: (prospective memor* OR memor* for intentions) AND (neuropsychological assessment) AND (test* OR instrument* OR questionnaire* OR task*) AND (psychometric properties) AND (child* OR adolescen*). Relevant studies identified in the reference lists were also included in the review. RESULTS: Ten instruments were identified and classified into three categories: (a) test batteries, (b) experimental procedures, and (c) questionnaires. All the instruments identified were described concerning their content and the psychometric properties available. Some of the instruments presented empirical evidence regarding validity and reliability, but no one provided normative data. CONCLUSION: Besides the recent progress regarding studies publishing the development of a variety of novel measures, there are still many limitations surrounding the assessment of PM in the youth population because of the yet incipient psychometric properties presented by the majority of the PM instruments. Recommendations for a gold-standard PM instrument for assessing children and adolescents are provided.

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