ABSTRACT
OBJECTIVES: A systematic review and meta-analysis of the literature was conducted to compare the accuracy with which flexible endoscopic evaluation of swallowing (FEES) and videofluoroscopic swallowing study (VFSS) assessed oropharyngeal dysphagia in adults. DATA SOURCES: PubMed, Embase, and the Latin American and Caribbean Health Sciences Literature (LILACS) database. METHODS: A review of published studies was conducted in parallel by two groups of researchers. We evaluated the methodological quality, homogeneity, threshold effect, and publication bias. The results are presented as originally published, then with each test compared against the other as a reference and both compared against a composite reference standard, and then pooled using a random effects model. Software use consisted of Meta-DiSc and SPSS. RESULTS: The search yielded 5,697 articles. Fifty-two articles were reviewed in full text, and six articles were included in the meta-analysis. FEES showed greater sensitivity than VFSS for aspiration (0.88 vs. 0.77; P = .03), penetration (0.97 vs. 0.83; P = .0002), and laryngopharyngeal residues (0.97 vs. 0.80; P < .0001). Sensitivity to detect pharyngeal premature spillage was similar for both tests (VFSS: 0.80; FEES: 0.69; P = .28). The specificities of both tests were similar (range, 0.93-0.98). In the sensitivity analysis there were statistically significant differences between the tests regarding residues but only marginally significant differences regarding aspiration and penetration. CONCLUSIONS: FEES had a slight advantage over VFSS to detect aspiration, penetration, and residues. Prospective studies comparing both tests against an appropriate reference standard are needed to define which test has greater accuracy. LEVEL OF EVIDENCE: 2a Laryngoscope, 127:2002-2010, 2017.
Subject(s)
Deglutition Disorders/diagnosis , Esophagoscopy/methods , Fluoroscopy/methods , Adult , Deglutition/physiology , Female , Humans , Male , Pharynx/physiopathology , Sensitivity and Specificity , Video RecordingABSTRACT
Neurologically impaired children have a high incidence of coexistent respiratory problems, of multifactorial etiology. Among the main related factors are: ineffective cough, hypersalivation, dysphagia, gastroesophageal reflux and lung restriction secondary to chest wall deformity. Because of this, patients with cerebral palsy and neuromuscular diseases present a high prevalence of pulmonary aspiration, which has very varied and sometimes complex clinical manifestations. a variety of imaging exams are available to clarify the etiological diagnosis of the neurological affectation (Computed Tomography -CT- and magnetic Resonance mR), and evaluate the gastrointestinal compromise of this patients, including the diagnosis of anterograde and retrograde aspiration (upper gi Barium Radiography and Videofluoroscopic swallowing study). An early and accurate imaging diagnosis allows an appropriate clinical management, which anticipates the possible complications and allows us to choose the therapies that improve the quality of life of these children.
Los niños con severos déficits neurológicos tienen una alta incidencia de problemas respiratorios, de etiología multifactorial. Entre los factores asociados destacan la tos inefectiva, sialorrea, disfagia, reflujo gastroesofágico y restricción pulmonar secundaria a deformidades de la caja torácica. Por lo anterior, los pacientes con parálisis cerebral y enfermedades neuromusculares presentan una alta incidencia de aspiración pulmonar cuyas manifestaciones clínicas son variadas y a veces complejas. La imaginología cuenta con exámenes que resultan de utilidad en precisar el diagnóstico etiológico del compromiso neurológico (tomografía computarizada, TC, y resonancia magnética), diagnosticar y evaluar el compromiso pulmonar (radiografías simples y TC) y valorar el compromiso gastrointestinal, incluyendo el diagnóstico de aspiración anterógrada y retrógrada (radiografía de esófago-estómago-duodeno y videofluoroscopía de deglución). Un adecuado diagnóstico por imágenes permite un manejo clínico adecuado que se anticipe a las posibles complicaciones y permita elegir terapias que mejoren la calidad de vida de estos niños.