A study of auxiliary factors for judges in sentencing dangerous driving offenses - the mediating role of favorable and unfavorable factors.

This paper investigates the ancillary factors judges consider when sentencing dangerous driving offenses. These factors are divided into favorable (i.e., "Confess" [CF], and "Actively compensate and obtain forgiveness from victims" [AC]) and unfavorable categories (i.e., "Mainly or solely responsible for the accident" [MSR], and "Post-accident behavior" [BAA]). Results indicate that both types of factors mediate the relationship between "Blood Alcohol Concentration" (BAC) and the sentencing outcome: favorable factors have a significant negative correlation with sentences, while unfavorable ones show a positive correlation. The mediation effect ratios are 13.8% and 19.1% respectively, with no significant differences between their impacts on judges' sentencing decisions.

RNA polymerases from low G+C gram-positive bacteria.

The low G + C Gram-positive bacteria represent some of the most medically and industrially important microorganisms. They are relied on for the production of food and dietary supplements, enzymes and antibiotics, as well as being responsible for the majority of nosocomial infections and serving as a reservoir for antibiotic resistance. Control of gene expression in this group is more highly studied than in any bacteria other than the Gram-negative model  Escherichia coli, yet until recently no structural information on RNA polymerase (RNAP) from this group was available. This review will summarize recent reports on the high-resolution structure of RNAP from the model low G + C representative  Bacillus subtilis, including the role of auxiliary subunits δ and ε, and outline approaches for the development of antimicrobials to target RNAP from this group.

Connecting Chlorophyll Metabolism with Accumulation of the Photosynthetic Apparatus.

Chlorophyll (Chl) is indispensable for photosynthesis. In association with Chl-binding proteins (CBPs), it is responsible for light absorption, excitation energy transfer, and charge separation within the photosynthetic complexes. By contrast, photoexcitation of free Chl and its metabolic intermediates generates hazardous reactive oxygen species (ROS). While antagonistic activities of Chl synthesis and catabolism have been mostly elucidated, the tight synchronization of these metabolic activities with the formation and dismantling of the photosynthetic complexes is poorly understood. Recently, a set of auxiliary factors were identified to adjust metabolic activities and provide accurate amounts of Chl for pigment-protein complexes. Here, we review current knowledge of post-translational coordination of Chl formation, breakdown, and turnover with the assembly and disassembly of various CBPs and highlight future research perspectives.