Subject(s)
Absorbable Implants , Angioplasty, Balloon, Coronary/instrumentation , Coronary Artery Disease/therapy , Stents , Absorbable Implants/history , Angioplasty, Balloon, Coronary/adverse effects , Angioplasty, Balloon, Coronary/history , Animals , Coronary Angiography , Coronary Artery Disease/diagnostic imaging , Coronary Artery Disease/history , Drug-Eluting Stents , History, 20th Century , History, 21st Century , Humans , Prosthesis Design , Stents/history , Treatment OutcomeSubject(s)
Suture Techniques/history , Absorbable Implants/history , Anastomosis, Surgical/history , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , History, 20th Century , History, 21st Century , History, Ancient , History, Medieval , Humans , Sutures/history , Vascular Surgical Procedures/historyABSTRACT
Today, more than 200years after the first production of metallic magnesium by Sir Humphry Davy in 1808, biodegradable magnesium-based metal implants are currently breaking the paradigm in biomaterial science to develop only highly corrosion resistant metals. This groundbreaking approach to temporary metallic implants is one of the latest developments in biomaterials science that is being rediscovered. It is a challenging topic, and several secrets still remain that might revolutionize various biomedical implants currently in clinical use. Magnesium alloys were investigated as implant materials long ago. A very early clinical report was given in 1878 by the physician Edward C. Huse. He used magnesium wires as ligature for bleeding vessels. Magnesium alloys for clinical use were explored during the last two centuries mainly by surgeons with various clinical backgrounds, such as cardiovascular, musculoskeletal and general surgery. Nearly all patients benefited from the treatment with magnesium implants. Although most patients experienced subcutaneous gas cavities caused by rapid implant corrosion, most patients had no pain and almost no infections were observed during the postoperative follow-up. This review critically summarizes the in vitro and in vivo knowledge and experience that has been reported on the use of magnesium and its alloys to advance the field of biodegradable metals.
Subject(s)
Absorbable Implants/history , Magnesium/history , Animals , Cardiac Surgical Procedures , Corrosion , History, 19th Century , History, 20th Century , History, 21st Century , HumansABSTRACT
Joseph Lister is associated with pioneering work on antisepsis. However an important but less well-known contribution to surgical progress was his work on the absorbable suture. This article details the problems Lister faced in operative surgery, his observations and experiments that lead to his development of an absorbable suture.