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Rheumatol Int ; 30(7): 973-5, 2010 May.
Article in English | MEDLINE | ID: mdl-19536544

ABSTRACT

Neuropathic arthropathy (Charcot's arthropathy) is a progressive articular disease associated with a reduced sensorial and protector proprioceptive reflex. Its etiology includes many different conditions such as syringomyelia, traumatic lesion causing medullary deformity, spina bifida, diabetic neuropathy, leprosy neuropathy, neurofibromatosis, amyloid neuropathy, alcohol, and repetitive injection of hydrocortisone into joints, among others. However, the relationship between Charcot's arthropathy and herpetic encephalitis has not yet been described. Herpes encephalitis causes acute and chronic diseases of the peripheral or central nervous system. It can manifest as subacute encephalitis, recurrent meningitis, or myelitis. It can also resemble psychiatric syndromes, diplopia, sensory changes in the face and limbs, personality changes, frontal dysexecutive syndrome, stiff neck, subclinical alterations of the vestibular function, intracranial hypertension, convulsion, hemiparesis, and generally includes motor components, among others. On the other hand, pure peripheral sensory disturbance has not been described. In this article, we report the clinical case of a patient with Charcot's arthropathy secondary to pure peripheral sensory polyneuropathy as a consequence of progressive herpetic encephalitis sequelae. In this article, the authors report the first case of Charcot's arthropathy secondary to herpetic encephalitis.


Subject(s)
Arthropathy, Neurogenic/immunology , Encephalitis, Herpes Simplex/complications , Peripheral Nervous System Diseases/immunology , Peripheral Nervous System Diseases/virology , Afferent Pathways/immunology , Afferent Pathways/pathology , Afferent Pathways/virology , Ankle Joint/diagnostic imaging , Ankle Joint/innervation , Ankle Joint/pathology , Arthropathy, Neurogenic/diagnostic imaging , Arthropathy, Neurogenic/pathology , Disease Progression , Elbow Joint/diagnostic imaging , Elbow Joint/innervation , Elbow Joint/pathology , Humans , Male , Middle Aged , Peripheral Nerves/diagnostic imaging , Peripheral Nerves/immunology , Peripheral Nerves/pathology , Peripheral Nervous System Diseases/physiopathology , Radiography , Sensory Receptor Cells/immunology , Sensory Receptor Cells/pathology , Sensory Receptor Cells/virology
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