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1.
J Subst Use Addict Treat ; 153: 208963, 2023 10.
Article in English | MEDLINE | ID: mdl-37654011

ABSTRACT

INTRODUCTION: Racial/ethnic discrimination and ethnic identity, the affiliation and connection to one's ethnic group, are important for understanding alcohol, tobacco, and drug use disorders (AUD, TUD, DUD, respectively) among Hispanic/Latin American individuals. Although discrimination is a well-recognized risk factor, the role of ethnic identity is less understood. Moreover, no study has examined which of these factors is more important for informing AUD, TUD, and DUD. This information is necessary for creating effective prevention and treatment programs tailored for Hispanic/Latin American people. Herein we examined the role and relative importance of racial/ethnic discrimination and Hispanic ethnic identity on past year AUD, TUD, and DUD. METHODS: Hispanic/Latin American participants of the National Epidemiologic Survey on Alcohol and Related Conditions-III constituted the sample for this cross-sectional secondary data analysis. Participants (N = 7037) were 39.93 years old on average (SD = 15.32). More than half were female (56.1 %) and had family incomes below the median household income in the United States (58.7 %). Most had national origins in North America (79.3 %), including US dependent territories and Mexico. Confirmatory factor analysis (CFA) verified the psychometric properties of the discrimination and Hispanic ethnic identity measures. Logistic regressions, supplemented with dominance analysis, estimated the role and relative contribution of discrimination and Hispanic ethnic identity on the probability of past year AUD, TUD, and DUD. RESULTS: The CFAs yielded adequate convergent validity and reliability for each construct. More racial/ethnic discrimination and a higher Hispanic ethnic identity related to a higher and lower probability of AUD, TUD, and DUD, respectively. The magnitude of the association between Hispanic ethnic identity and the probability of TUD exceeded that of racial/ethnic discrimination, but the converse was the case for AUD and DUD. CONCLUSIONS: Prevention and treatment programs for TUD that highlight the value of having a strong sense of self as a member of a Hispanic ethnic group, and that encourage the individual to explore their Hispanic ancestry may prove effective among Hispanic/Latin American individuals, particularly those who have experienced racial/ethnic discrimination. Programs for AUD and DUD tailored for Hispanic Latin/American adults should also incorporate coping strategies to address experiences with racial/ethnic discrimination.


Subject(s)
Alcoholism , Substance-Related Disorders , Tobacco Use Disorder , Adult , Female , Humans , Male , Cross-Sectional Studies , Hispanic or Latino , Reproducibility of Results , Substance-Related Disorders/ethnology , Tobacco Use Disorder/ethnology , Alcoholism/ethnology , United States
2.
J Ethn Subst Abuse ; 22(4): 782-803, 2023.
Article in English | MEDLINE | ID: mdl-35073229

ABSTRACT

This study explores stigma-related beliefs within the Latino community concerning alcohol misuse. A community-based convenience sample of 251 self-identified Latino adults were recruited to participate in a research study using an experimental vignette methodology. Participants were randomly assigned one of four vignettes about alcohol misuse and asked to share their attitudes and stigma-related beliefs about the problem and the person in the vignette. Sociodemographic characteristics of participants differentially predicted alcohol-related stigma. These data may be used to inform health literacy and stigma reduction interventions within the Latino community.


Subject(s)
Alcoholism , Hispanic or Latino , Social Stigma , Humans , Alcoholism/epidemiology , Alcoholism/ethnology , Hispanic or Latino/psychology , Hispanic or Latino/statistics & numerical data
3.
J Gerontol Soc Work ; 66(4): 491-511, 2023.
Article in English | MEDLINE | ID: mdl-36190695

ABSTRACT

Recent declines in life expectancy in the US, especially for middle-aged White persons, have called attention to mortality from deaths of despair - deaths due to alcohol, drugs, and suicide. Using data from the Centers for Disease Control and the U.S. Census Bureau, this paper examined deaths of despair by race/ethnicity, age, cause of death, birth cohort, and sex in Missouri. We focused on Area Agencies on Aging as geographic units of interest to increase usefulness of our findings to public administrators. Deaths of despair began trending up for all age groups beginning in 2007-2009, with the sharpest increases occurring for Black or African American non-Hispanics beginning in 2013-2015. The most dramatic increases occurred for the population age 50-59 in St. Louis City and Area Agency on Aging regions in southern Missouri. For older adults, considerable variation in rates, trends, and cause of deaths of despair is evident across the state.


Subject(s)
Aging , Black or African American , Substance-Related Disorders , Suicide , Aged , Humans , Middle Aged , Aging/ethnology , Aging/psychology , Black or African American/psychology , Black or African American/statistics & numerical data , Missouri/epidemiology , Suicide/ethnology , Suicide/psychology , Suicide/statistics & numerical data , United States , Alcoholism/epidemiology , Alcoholism/ethnology , Alcoholism/mortality , Alcoholism/psychology , Substance-Related Disorders/epidemiology , Substance-Related Disorders/ethnology , Substance-Related Disorders/mortality , Substance-Related Disorders/psychology
4.
Subst Use Misuse ; 57(5): 708-718, 2022.
Article in English | MEDLINE | ID: mdl-35156525

ABSTRACT

OBJECTIVE: Prior research shows that Black/African American adults experience more negative alcohol use consequences than White adults, despite lower alcohol consumption. Research also shows that Black/African Americans experience higher rates of depression, which can increase risk for alcohol consumption and alcohol use disorder (AUD) through drinking to cope. We examined associations between depressive symptoms and drinking to cope with alcohol consumption and AUD symptoms among White and Black/African American college students. METHODS: Participants completed an online survey during the fall and spring semester of their first year of college (N = 2,168, 62.8% female, 75.8% White). Path analyses were conducted to examine whether depressive symptoms and drinking to cope mediated the association between race/ethnicity and alcohol use outcomes, and whether race/ethnicity moderated the associations between depressive symptoms, drinking to cope, and alcohol use outcomes. RESULTS: Results indicated that Black/African Americans had lower levels of depressive symptoms, which were associated with lower drinking to cope, and in turn associated with lower alcohol consumption and AUD symptoms. Multigroup analysis indicated that the pattern of associations between depressive symptoms, drinking to cope, and alcohol use outcomes were largely similar between White and Black/African American college students and between males and females, except that the association between depressive symptoms and drinking to cope appeared to be stronger for Whites than for Black/African American students. CONCLUSION: Depressive symptoms and drinking to cope are risk factors in relation to alcohol use outcomes among White and Black/African American college students and partially account for the link between race/ethnicity and alcohol use outcomes.Supplemental data for this article is available online at https://doi.org/10.1080/10826084.2022.2034871 .


Subject(s)
Alcohol Drinking in College/ethnology , Alcohol Drinking/psychology , Alcoholism/ethnology , Black or African American , Depression/ethnology , Adaptation, Psychological , Adult , Alcohol Drinking/epidemiology , Depression/complications , Depression/epidemiology , Female , Humans , Male , Students , Surveys and Questionnaires , Universities
5.
Addict Biol ; 27(1): e13099, 2022 01.
Article in English | MEDLINE | ID: mdl-34611967

ABSTRACT

Polygenic risk scores (PRS) represent an individual's summed genetic risk for a trait and can serve as biomarkers for disease. Less is known about the utility of PRS as a means to quantify genetic risk for substance use disorders (SUDs) than for many other traits. Nonetheless, the growth of large, electronic health record-based biobanks makes it possible to evaluate the association of SUD PRS with other traits. We calculated PRS for smoking initiation, alcohol use disorder (AUD), and opioid use disorder (OUD) using summary statistics from the Million Veteran Program sample. We then tested the association of each PRS with its primary phenotype in the Penn Medicine BioBank (PMBB) using all available genotyped participants of African or European ancestry (AFR and EUR, respectively) (N = 18,612). Finally, we conducted phenome-wide association analyses (PheWAS) separately by ancestry and sex to test for associations across disease categories. Tobacco use disorder was the most common SUD in the PMBB, followed by AUD and OUD, consistent with the population prevalence of these disorders. All PRS were associated with their primary phenotype in both ancestry groups. PheWAS results yielded cross-trait associations across multiple domains, including psychiatric disorders and medical conditions. SUD PRS were associated with their primary phenotypes; however, they are not yet predictive enough to be useful diagnostically. The cross-trait associations of the SUD PRS are indicative of a broader genetic liability. Future work should extend findings to additional population groups and for other substances of abuse.


Subject(s)
Comorbidity , Electronic Health Records/statistics & numerical data , Genetic Predisposition to Disease/genetics , Substance-Related Disorders/ethnology , Substance-Related Disorders/genetics , Adult , Aged , Aged, 80 and over , Alcoholism/ethnology , Alcoholism/genetics , Black People/genetics , Female , Genome-Wide Association Study , Genotype , Humans , Male , Middle Aged , Multifactorial Inheritance , Opioid-Related Disorders/ethnology , Opioid-Related Disorders/genetics , Phenotype , Risk Factors , Sex Factors , Tobacco Use Disorder/ethnology , Tobacco Use Disorder/genetics , White People/genetics
6.
J Ethn Subst Abuse ; 21(1): 174-196, 2022.
Article in English | MEDLINE | ID: mdl-32065558

ABSTRACT

The study explored associations among childhood abuse, post-traumatic stress symptoms (PTSS), and alcohol misuse in a sample of low-income African-American women (N = 172). Using bootstrapping techniques, a mediation effect was found of childhood physical and emotional abuse on alcohol misuse via PTSS symptom severity, avoidance, and hyperarousal, as well as for childhood sexual abuse on alcohol misuse via PTSS symptom severity and hyperarousal. Our results suggest that PTSS indicators, particularly symptom severity and hyperarousal, may be important mechanisms underlying the association of experiences of abuse during childhood and alcohol misuse in adulthood.


Subject(s)
Alcoholism/etiology , Child Abuse/ethnology , Child Abuse/psychology , Stress Disorders, Post-Traumatic , Adult , Black or African American , Alcoholism/epidemiology , Alcoholism/ethnology , Alcoholism/psychology , Child , Female , Humans , Stress Disorders, Post-Traumatic/epidemiology , United States/epidemiology
7.
Interface (Botucatu, Online) ; 26: e210516, 2022. ilus
Article in Portuguese | LILACS | ID: biblio-1405326

ABSTRACT

O objetivo deste artigo é compreender os significados do alcoolismo de uma maneira êmica, isto é, tal como ele é concebido e vivenciado por mulheres que frequentam uma reunião feminina de Alcoólicos Anônimos (AA). Realizou-se uma pesquisa qualitativa, de abordagem etnográfica, em uma reunião exclusiva de mulheres em um grupo localizado na cidade de São Paulo, Brasil. O alcoolismo está ligado às assimetrias de gênero, que estabelecem uma diferença entre homens e mulheres em relação ao uso de bebidas alcoólicas, de modo que a reunião feminina de AA possui uma dimensão política que se contrapõe à cultura patriarcal de AA ao garantir às mulheres um espaço de gênero, moral e politicamente, privilegiado para que elas possam compartilhar e significar suas experiências e, por essa via, realizar seu tratamento do alcoolismo.(AU)


The aim of this emic study of alcoholism was to understand how this problem is conceived and experienced by women attending a women-only Alcoholics Anonymous (AA) meeting. We conducted an ethnographic study with a women's AA group in São Paulo, Brazil. Alcoholism is linked to gender asymmetries, which establish a difference between men and women in relation to drinking. Women-only AA meetings therefore possess a political dimension that counterposes AA's patriarchal culture by providing women with a morally and politically unique gendered space that allows them to share and signify their experiences and, in this way, treat their alcoholism.(AU)


El objetivo de este artículo es comprender los significados del alcoholismo de una manera émica, es decir, tal como es concebido y vivido por mujeres que frecuentan una reunión femenina de Alcohólicos Anónimos (AA). Se realizó una investigación cualitativa, de abordaje etnográfico, en una reunión exclusiva de mujeres en un grupo localizado en la Ciudad de São Paulo, Brasil. El alcoholismo está vinculado a las asimetrías de género que establecen una diferencia entre hombres y mujeres con relación al uso de bebidas alcohólicas, de modo que la reunión femenina de AA tiene una dimensión política que se contrapone a la cultura patriarcal de AA al asegurar a las mujeres un espacio de género, moral y políticamente privilegiado para que ellas puedan compartir y significar sus experiencias y, por esa vía, realizar su tratamiento del alcoholismo.(AU)


Subject(s)
Humans , Female , Adult , Middle Aged , Aged , Women/psychology , Alcoholics Anonymous , Alcoholism/ethnology , Anthropology, Cultural/methods , Brazil , Qualitative Research , Gender Role
8.
PLoS One ; 16(12): e0260319, 2021.
Article in English | MEDLINE | ID: mdl-34879064

ABSTRACT

BACKGROUND: Aside from human papillomavirus (HPV), the role of other risk factors in cervical cancer such as age, education, parity, sexual partners, smoking and human immunodeficiency virus (HIV) have been described but never ranked in order of priority. We evaluated the contribution of several known lifestyle co-risk factors for cervical cancer among black South African women. METHODS: We used participant data from the Johannesburg Cancer Study, a case-control study of women recruited mainly at Charlotte Maxeke Johannesburg Academic Hospital between 1995 and 2016. A total of 3,450 women in the study had invasive cervical cancers, 95% of which were squamous cell carcinoma. Controls were 5,709 women with cancers unrelated to exposures of interest. Unconditional logistic regression models were used to calculate adjusted odds ratios (ORadj) and 95% confidence intervals (CI). We ranked these risk factors by their population attributable fractions (PAF), which take the local prevalence of exposure among the cases and risk into account. RESULTS: Cervical cancer in decreasing order of priority was associated with (1) being HIV positive (ORadj = 2.83, 95% CI = 2.53-3.14, PAF = 17.6%), (2) lower educational attainment (ORadj = 1.60, 95% CI = 1.44-1.77, PAF = 16.2%), (3) higher parity (3+ children vs 2-1 children (ORadj = 1.25, 95% CI = 1.07-1.46, PAF = 12.6%), (4) hormonal contraceptive use (ORadj = 1.48, 95% CI = 1.24-1.77, PAF = 8.9%), (5) heavy alcohol consumption (ORadj = 1.44, 95% CI = 1.15-1.81, PAF = 5.6%), (6) current smoking (ORadj = 1.64, 95% CI = 1.41-1.91, PAF = 5.1%), and (7) rural residence (ORadj = 1.60, 95% CI = 1.44-1.77, PAF = 4.4%). CONCLUNSION: This rank order of risks could be used to target educational messaging and appropriate interventions for cervical cancer prevention in South African women.


Subject(s)
Alcoholism/epidemiology , Carcinoma, Squamous Cell/epidemiology , Papillomavirus Infections/epidemiology , Smoking/epidemiology , Uterine Cervical Neoplasms/epidemiology , Adult , Alcoholism/complications , Alcoholism/ethnology , Carcinoma, Squamous Cell/ethnology , Carcinoma, Squamous Cell/virology , Case-Control Studies , Female , Hospitals, Teaching , Humans , Life Style , Logistic Models , Middle Aged , Papillomavirus Infections/ethnology , Parity , Pregnancy , Prevalence , Smoking/adverse effects , South Africa/epidemiology , Uterine Cervical Neoplasms/ethnology , Uterine Cervical Neoplasms/virology
9.
Alcohol Clin Exp Res ; 45(11): 2309-2321, 2021 11.
Article in English | MEDLINE | ID: mdl-34837658

ABSTRACT

BACKGROUND: Belief in the myth of an American Indian/Alaska Native (AIAN)-specific biological vulnerability (BV) to alcohol problems is associated with worse alcohol outcomes among AIAN college students who drink, despite also being associated with greater attempts to reduce drinking. This study examined the association of belief in a BV with alcohol use among reservation-dwelling AI adults with a substance use problem. METHODS: Participants (n = 141) who drank alcohol in the past 90 days were selected from a larger AI sample who self-identified as having a substance use problem. Moderated-mediation analyses examined whether belief in a BV was positively associated with alcohol- and substance use-related consequences and whether self-efficacy and craving mediated the association of belief in a BV with alcohol use. RESULTS: Among participants who reported using alcohol but not hard drugs (e.g., methamphetamine, opioids), greater belief in a BV was associated with more drinking days, which in turn was associated with greater alcohol-related consequences. Among participants who used alcohol only, belief in a BV was also significantly associated with greater craving, and in turn with more drinking days. Among individuals who used both alcohol and hard drugs, greater belief in a BV was associated with fewer drinking days, but was not significantly associated with substance use-related consequences. No association was found between belief in a BV and self-efficacy to avoid alcohol or drug use. CONCLUSIONS: Among individuals who use only alcohol, belief in a BV may contribute to more drinking days and greater alcohol-related consequences through its association with greater craving. This study provides further evidence of the potential harm of internalizing the belief that being AIAN contributes to the risk for alcohol problems, a notion that lacks scientific evidence despite decades of research. The findings highlight the importance of combating societal myths regarding AIAN peoples and the internalization of these stereotypes.


Subject(s)
/statistics & numerical data , Alcohol-Related Disorders/epidemiology , Alcoholism/ethnology , Minority Groups/psychology , Stereotyping , Adolescent , Adult , Alaska , Alcohol Drinking/epidemiology , Binge Drinking/ethnology , Humans , Male , Motivation , Self Efficacy , Students/statistics & numerical data
10.
Medicine (Baltimore) ; 100(43): e27343, 2021 Oct 29.
Article in English | MEDLINE | ID: mdl-34713823

ABSTRACT

OBJECTIVES: Reported associations of the cannabinoid receptor 1 (CNR1) single nucleotide polymorphisms (SNPs) with alcohol dependence (AD) have been inconsistent, prompting a meta-analysis to obtain more precise estimates. METHODS: A Boolean search of 4 databases (PubMed, Scopus, Google Scholar, and Mednar) sought articles that evaluated the association between CNR1 polymorphisms and risk of AD. We selected the articles with sufficient genotype frequency data to enable calculation of odds ratios (ORs) and 95% confidence intervals (CIs). Using the Population Intervention Comparators Outcome elements, AD patients (P) were compared by genotype data between AD-participants (I) and non-AD-participants (C) in order to determine the risk of AD (O) attributed to the CNR1 SNPs. Analyzing 4 SNPs (rs1049353, rs1535255, rs2023239, and rs806379) using standard genetic models, we examined associations where multiple comparisons were Holm-Bonferroni corrected. The pooled ORs were assessed for aggregate statistical power and robustness (sensitivity analysis). Subgroups were Caucasians and African-Americans. RESULTS: From 32 comparisons, 14 were significant indicating increased risk, from which 5 outcomes (P-value for association [Pa] = .003 to <.001) survived the Holm-Bonferroni-correction, which were deemed robust. In the rs1535255 outcomes, the codominant effect (OR = 1.43, 95% CIs = 1.24-1.65, Pa < .001) had greater statistical power than the dominant effect (OR = 1.30, 95% CI = 1.08-1.57, Pa = .006). In contrast, the rs2023239 codominant outcome was underpowered. Significance of both rs806379 Caucasian outcomes (ORs = 1.20-1.43, 95% CIs = 1.07-1.57, Pa = .003) contrasted with the null effects in African-Americans (ORs = 0.98-1.08, 95% CIs = 0.70-1.53). CONCLUSIONS: Three CNR1 SNPs (rs1535255, rs2023239, and rs806379) were implicated in their associations with development of AD: based on aggregate statistical power, rs1535255 presented greater evidence for associations than rs2023239; rs806379 implicated the Caucasian subgroup. Multiple statistical and meta-analytical features (consistency, robustness, and high significance) underpinned the strengths of these outcomes. Our findings could render the CNR1 polymorphisms useful in the clinical genetics of AD.


Subject(s)
Alcoholism/genetics , Receptor, Cannabinoid, CB1/genetics , Black or African American , Alcoholism/ethnology , Genetic Predisposition to Disease , Genome-Wide Association Study , Genotype , Humans , Meta-Analysis as Topic , Polymorphism, Single Nucleotide , White People
11.
Alcohol Clin Exp Res ; 45(8): 1653-1663, 2021 08.
Article in English | MEDLINE | ID: mdl-34388267

ABSTRACT

BACKGROUND: Alcohol use is disproportionately higher among multiracial than monoracial adults; yet, associated risk and protective factors are underexplored. The present study compared levels of experienced racial discrimination, racial identity affiliation, and heavy alcohol use among multiracial and monoracial adults and tested whether racial identity affiliation, experienced racial discrimination, and their interaction were significantly associated with heavy alcohol use among multiracial individuals. METHODS: We conducted secondary analyses of data from the National Epidemiologic Survey on Alcohol and Related Conditions-III. Participants are a nationally representative sample of all U.S. adults (N = 29,026; 56.4% female) and were interviewed for the study from 2012 to 2013. The sample includes 598multiracial individuals. RESULTS: Linear regression analyses showed that multiracial individuals experienced significantly greater racial discrimination than White (b = -1.26, 95% CI [-1.47, -1.05], p < 0.001) or Asian individuals (b = -0.30, 95% CI [-0.53, -0.06], p = 0.013) but less than Black individuals (b = 0.29, 95% CI [0.08, 0.50], p = 0.007). Furthermore, multiracial individuals reported less affiliation with their racial identity than Black (b = 4.92, 95% CI [4.23, 5.62], p < 0.001) or Asian individuals (b = 3.86, 95% CI [3.09, 4.63], p < 0.001) but did not differ significantly from White individuals. Logistic regression analysis showed that multiracial individuals were significantly more likely to report heavy drinking than Asian individuals (OR = 0.53, 95% CI [0.36, 0.78], p = 0.001) but did not differ significantly from White or Black individuals. Finally, experienced racial discrimination was significantly related to heavy alcohol use in multiracial adults (b = 0.11, 95% CI [0.01, 0.20], p = 0.031), though neither racial identity affiliation nor the interaction of racial identity affiliation with experienced racial discrimination were significantly related to heavy alcohol use. CONCLUSIONS: Our results suggest that multiracial individuals, as compared to other minoritized individuals who are monoracial, report high levels of experienced racial discrimination and heavy alcohol use and low levels of racial identity affiliation. Further understanding of the effects of racial identity affiliation and experienced racial discrimination on the risk for heavy alcohol use could help in the development of interventions aimed at reducing alcohol use disparities among multiracial individuals.


Subject(s)
Alcoholism/ethnology , Racism/ethnology , Social Identification , Adult , Aged , Alcoholism/psychology , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Racism/psychology , United States/epidemiology
12.
Psychol Addict Behav ; 35(5): 501-513, 2021 Aug.
Article in English | MEDLINE | ID: mdl-34110841

ABSTRACT

BACKGROUND: Family history of alcohol use disorder; AUD (FH +) and impulsivity-related traits are known risk factors for problem drinking that have been investigated in predominately White samples. This cross-sectional study examined whether these risk factors vary by sex in the overall, majority White sample and in a Black subsample. METHOD: A model building regression procedure was used to investigate the combined effect of FH + and impulsivity-related traits on alcohol quantity, frequency, and problems by sex (overall sample: N = 757, 50% female, 73% White, agemean = 33.74, SD = 11.60; Black subsample: n = 138, 47% female, agemean = 33.60, SD = 9.87). RESULTS: Overall Sample. No sex differences were found in the compounding effects of FH + and impulsivity-related traits on alcohol outcomes. Males reported more physical, social, and overall alcohol-related problems than females. FH + was positively associated with all alcohol-related consequences. Poor self-regulation was the only trait associated with all alcohol outcomes. Black Subsample: A three-way interaction suggested a negative association between inhibition and frequency of alcohol use among FH + males only. A two-way interaction also suggested impulse control was associated with more interpersonal alcohol-related problems among males only. Main effects were also found in the expected direction such that higher impulsivity and FH + were associated with poorer alcohol outcomes. CONCLUSION: These findings suggest no sex differences in the overall sample in the interactive effects of established risk factors for AUD on alcohol outcomes, and that poor self-regulation may be key for personality-targeted alcohol prevention and intervention programs. Preliminary findings of sex differences in the Black subsample should be replicated. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Alcohol-Related Disorders , Alcoholism , Individuality , Adult , Black or African American/psychology , Black or African American/statistics & numerical data , Alcohol-Related Disorders/epidemiology , Alcohol-Related Disorders/ethnology , Alcohol-Related Disorders/psychology , Alcoholism/epidemiology , Alcoholism/ethnology , Alcoholism/psychology , Cross-Sectional Studies , Female , Humans , Impulsive Behavior , Male , Medical History Taking/statistics & numerical data , Risk Factors , Sex Distribution , White People/psychology , White People/statistics & numerical data
13.
Am J Epidemiol ; 190(9): 1751-1759, 2021 09 01.
Article in English | MEDLINE | ID: mdl-33778856

ABSTRACT

Life expectancy for US White men and women declined between 2013 and 2017. Initial explanations for the decline focused on increases in "deaths of despair" (i.e., deaths from suicide, drug use, and alcohol use), which have been interpreted as a cohort-based phenomenon afflicting middle-aged White Americans. There has been less attention on Black mortality trends from these same causes, and whether the trends are similar or different by cohort and period. We complement existing research and contend that recent mortality trends in both the US Black and White populations most likely reflect period-based exposures to 1) the US opioid epidemic and 2) the Great Recession. We analyzed cause-specific mortality trends in the United States for deaths from suicide, drug use, and alcohol use among non-Hispanic Black and non-Hispanic White Americans, aged 20-64 years, over 1990-2017. We employed sex-, race-, and cause-of-death-stratified Poisson rate models and age-period-cohort models to compare mortality trends. Results indicate that rising "deaths of despair" for both Black and White Americans are overwhelmingly driven by period-based increases in drug-related deaths since the late 1990s. Further, deaths related to alcohol use and suicide among both White and Black Americans changed during the Great Recession, despite some racial differences across cohorts.


Subject(s)
Black or African American/statistics & numerical data , Mortality , White People/statistics & numerical data , Adult , Black or African American/psychology , Alcoholism/ethnology , Alcoholism/mortality , Cause of Death/trends , Economic Recession , Female , Humans , Male , Middle Aged , Mortality/trends , Substance-Related Disorders/ethnology , Substance-Related Disorders/mortality , Suicide/ethnology , Suicide/statistics & numerical data , White People/psychology , Young Adult
14.
JAMA Psychiatry ; 78(6): 599-606, 2021 06 01.
Article in English | MEDLINE | ID: mdl-33656561

ABSTRACT

Importance: Many American Indian and Alaska Native communities are disproportionately affected by problems with alcohol use and seek culturally appropriate and effective interventions for individuals with alcohol use disorders. Objective: To determine whether a culturally tailored contingency management intervention, in which incentives were offered for biologically verified alcohol abstinence, resulted in increased abstinence among American Indian and Alaska Native adults. This study hypothesized that adults assigned to receive a contingency management intervention would have higher levels of alcohol abstinence than those assigned to the control condition. Design, Setting, and Participants: This multisite randomized clinical trial, the Helping Our Native Ongoing Recovery (HONOR) study, included a 1-month observation period before randomization and a 3-month intervention period. The study was conducted at 3 American Indian and Alaska Native health care organizations located in Alaska, the Pacific Northwest, and the Northern Plains from October 10, 2014, to September 2, 2019. Recruitment occurred between October 10, 2014, and February 20, 2019. Eligible participants were American Indian or Alaska Native adults who had 1 or more days of high alcohol-use episodes within the last 30 days and a current diagnosis of alcohol dependence. Data were analyzed from February 1 to April 29, 2020. Interventions: Participants received treatment as usual and were randomized to either the contingency management group, in which individuals received 12 weeks of incentives for submitting a urine sample indicating alcohol abstinence, or the control group, in which individuals received 12 weeks of incentives for submitting a urine sample without the requirement of alcohol abstinence. Regression models fit with generalized estimating equations were used to assess differences in abstinence during the intervention period. Main Outcomes and Measures: Alcohol-negative ethyl glucuronide (EtG) urine test result (defined as EtG<150 ng/mL). Results: Among 1003 adults screened for eligibility, 400 individuals met the initial criteria. Of those, 158 individuals (39.5%; mean [SD] age, 42.1 [11.4] years; 83 men [52.5%]) met the criteria for randomization, which required submission of 4 or more urine samples and 1 alcohol-positive urine test result during the observation period before randomization. A total of 75 participants (47.5%) were randomized to the contingency management group, and 83 participants (52.5%) were randomized to the control group. At 16 weeks, the number who submitted an alcohol-negative urine sample was 19 (59.4%) in the intervention group vs 18 (38.3%) in the control group. Participants randomized to the contingency management group had a higher likelihood of submitting an alcohol-negative urine sample (averaged over time) compared with those randomized to the control group (odds ratio, 1.70; 95% CI, 1.05-2.76; P = .03). Conclusions and Relevance: The study's findings indicate that contingency management may be an effective strategy for increasing alcohol abstinence and a tool that can be used by American Indian and Alaska Native communities for the treatment of individuals with alcohol use disorders. Trial Registration: ClinicalTrials.gov Identifier: NCT02174315.


Subject(s)
Alcohol Abstinence , Alcoholism/ethnology , Alcoholism/therapy , Culturally Competent Care/ethnology , Motivation , Adult , Female , Glucuronates/urine , Humans , Intersectoral Collaboration , Male , Middle Aged , Outcome Assessment, Health Care , Substance Abuse Detection , Urinalysis , American Indian or Alaska Native/ethnology
15.
Am J Addict ; 30(1): 26-33, 2021 01.
Article in English | MEDLINE | ID: mdl-32573050

ABSTRACT

BACKGROUND AND OBJECTIVES: Alcohol use disorder (AUD) is highly prevalent in US military veterans, though little is known about whether the psychiatric comorbidities and functional outcomes (ie, clinical features) of AUD differ across race/ethnic groups. We aimed to identify differences in the clinical features of veterans with AUD by race/ethnicity. METHODS: In a sample of veterans with AUD (n = 1212) from the nationally representative National Health and Resilience in Veterans Study, we compared the clinical features associated with AUD across racial/ethnic groups using analysis of covariance and logistic regression. RESULTS: Black veterans (n = 60, 34.0%) were less likely to screen positive for lifetime AUD compared with white (n = 1099, 42.7%) and Hispanic (n = 53, 41.5%) veterans. Among those with lifetime AUD, Hispanic veterans were more likely than white veterans to have lifetime and current mood or anxiety disorders (adjusted odds ratio range [AORR] = 2.21-2.52, P < .05). Black veterans were more likely than white veterans to have current mood and anxiety disorders (AORR = 2.01-3.07, P < .05). Hispanic veterans reported poorer functioning and quality of life than white and black veterans (Cohen's d range = 0.12-0.37, P < .05). DISCUSSION AND CONCLUSIONS: Black and Hispanic veterans with lifetime AUD may experience a higher disease burden relative to white veterans. Results underscore the importance of race/ethnicity-sensitive assessment, monitoring, and treatment of AUD for veterans. SCIENTIFIC SIGNIFICANCE: This is the first known study to examine differences by race/ethnicity in the clinical features of Veterans with AUD in a nationally representative sample. Findings suggest higher disease burden for racial/ethnic minority veterans. (Am J Addict 2021;30:26-33).


Subject(s)
Alcoholism/ethnology , Anxiety Disorders/ethnology , Depressive Disorder, Major/ethnology , Ethnicity/statistics & numerical data , Veterans/statistics & numerical data , Black or African American/psychology , Black or African American/statistics & numerical data , Alcoholism/psychology , Anxiety Disorders/psychology , Comorbidity , Cost of Illness , Depressive Disorder, Major/psychology , Ethnicity/psychology , Female , Hispanic or Latino/psychology , Hispanic or Latino/statistics & numerical data , Humans , Male , Middle Aged , Minority Groups , Patient Health Questionnaire , Prevalence , Quality of Life/psychology , United States , Veterans/psychology , White People/psychology , White People/statistics & numerical data
16.
Alcohol Alcohol ; 56(1): 74-81, 2021 Jan 04.
Article in English | MEDLINE | ID: mdl-33179048

ABSTRACT

AIMS: Greater neighborhood co-ethnic density (living in proximity with people sharing an ethnicity) and being foreign-born each can protect against risky drinking, but little is known about whether these two factors interact. Using a representative sample of Latinos and Asians from California, USA, we investigate main and interactive effects of neighborhood co-ethnic density and nativity status in relation to heavy episodic drinking (HED). METHODS: This study uses the California Health Interview Survey (N = 30,203) linked with neighborhood data to investigate associations of co-ethnic density and nativity status with HED. Co-ethnic density was based on matching each respondent's ethnicity to the proportion of residents of the corresponding group in their Census tract. Using weighted logistic regression, we first examined main effects of neighborhood co-ethnic density and respondent nativity status on HED. Next, we assessed the interaction of co-ethnic density and nativity status. Finally, we estimated nativity-stratified models to investigate variation in effects of co-ethnic density. RESULTS: Co-ethnic density was not associated with HED for the full sample, but US-born nativity status was associated with increased odds of past-year HED. The interaction model showed co-ethnic density and nativity had synergistic effects, whereby greater levels of neighborhood co-ethnic density buffered risk associated with being US-born. Further, greater neighborhood co-ethnic density was associated with reduced odds of HED for US-born respondents, but it was not associated with HED for foreign-born respondents. CONCLUSIONS: Protective effects of high neighborhood co-ethnic density on HED are stronger for US-born than for foreign-born Latinos and Asians in California.


Subject(s)
Asian/statistics & numerical data , Binge Drinking/ethnology , Emigrants and Immigrants/statistics & numerical data , Hispanic or Latino/statistics & numerical data , Residence Characteristics/statistics & numerical data , Alcoholism/epidemiology , Alcoholism/ethnology , Asia/ethnology , Binge Drinking/epidemiology , Ethnicity , Humans , Latin America/ethnology , Logistic Models
17.
Alcohol Res ; 40(2): 09, 2020.
Article in English | MEDLINE | ID: mdl-32904739

ABSTRACT

Although research on alcohol-related disparities among women is a highly understudied area, evidence shows that racial/ethnic minority women, sexual minority women, and women of low socioeconomic status (based on education, income, or residence in disadvantaged neighborhoods) are more likely to experience alcohol-related problems. These problems include alcohol use disorder, particularly after young adulthood, and certain alcohol-related health, morbidity, and mortality outcomes. In some cases, disparities may reflect differences in alcohol consumption, but in other cases such disparities appear to occur despite similar and possibly lower levels of consumption among the affected groups. To understand alcohol-related disparities among women, several factors should be considered. These include age; the duration of heavy drinking over the life course; the widening disparity in cumulative socioeconomic disadvantage and health in middle adulthood; social status; sociocultural context; genetic factors that affect alcohol metabolism; and access to and quality of alcohol treatment services and health care. To inform the development of interventions that might mitigate disparities among women, research is needed to identify the factors and mechanisms that contribute most to a group's elevated risk for a given alcohol-related problem.


Subject(s)
Alcohol-Related Disorders/ethnology , Ethnicity/statistics & numerical data , Healthcare Disparities/statistics & numerical data , Minority Groups/statistics & numerical data , Sexual and Gender Minorities/statistics & numerical data , Adult , Black or African American/statistics & numerical data , Alcohol Drinking/ethnology , Alcoholism/ethnology , Female , Health Status Disparities , Hispanic or Latino/statistics & numerical data , Humans , Middle Aged , Socioeconomic Factors , White People/statistics & numerical data , Young Adult
18.
Medicine (Baltimore) ; 99(38): e21884, 2020 Sep 18.
Article in English | MEDLINE | ID: mdl-32957309

ABSTRACT

The Dulong nationality is one of the 5 smallest ethnic minorities in China. The suicide rate among people of the Dulong nationality is very serious. To address this issue, we conducted cross-sectional epidemiological studies on the prevalence of mental disorders in ethnic groups. Studying the unique situation of ethnic minorities can help us better understand their mental state and improve their quality of life.We conducted a cross-sectional epidemiological survey on a minority group in Southwest China. We used the cluster sampling method, and 2129 people were included in the study.The highest 1-month disorder prevalence was for alcohol dependence/abuse (4.16%), and the prevalence of lifelong mood disorders was 9.82%. The results of multivariate analysis showed that women faced a higher risk of mood disorders and anxiety disorders.This epidemiological survey of the prevalence of mental disorders in ethnic minorities in Southwest China provides a significant reference for mental health interventions for other ethnic minorities around the world.


Subject(s)
Ethnicity/statistics & numerical data , Mental Disorders/ethnology , Adolescent , Adult , Aged , Alcoholism/ethnology , China/epidemiology , Cross-Sectional Studies , Female , Health Surveys , Humans , Male , Middle Aged , Prevalence , Quality of Life , Sex Factors , Socioeconomic Factors , Young Adult
19.
BMC Womens Health ; 20(1): 202, 2020 09 14.
Article in English | MEDLINE | ID: mdl-32928173

ABSTRACT

BACKGROUND: Type D personality is a combination of high negative affectivity (NA) and high social inhibition (SI). This personality trait is suspected to impair cardiovascular patients' recovery. The 2016 European Guidelines on cardiovascular disease prevention in clinical practice recommend screening of psychosocial risk factors as Type D personality. The aim of this study was to assess the relationship between Type D personality and Metabolic syndrome (MetS) in working-age female population. METHODS: Six hundred thirty-four female employees with mean age of 48 ± 10 years were evaluated. Type D personality and its components (NA) and (SI) were screened with DS14 questionnaire. The definition of MetS was based on measurements done by trained medical staff. We investigated the relationship between Mets and Type D personality, NA and SI using the logistic regression models adjusting for age, education years, leisure-time physical activity, smoking, alcohol use and depressive symptoms. RESULTS: The prevalence of Type D personality was 10.6% (n = 67) [95% CI: 8.3 to 13.2] and MetS 34.7% (n = 220). Type D personality or its subcomponents were not associated with MetS. Women with Type D personality had significantly worse quality of sleep and lower LTPA. They were also more often unsatisfied with their economic situation, they had more often depressive symptoms and psychiatric disorders than non-D type persons. There were no differences in risk factors for cardiovascular diseases. CONCLUSION: Screening for Type D personality among working- age, reasonably healthy female population seems not to be practical method for finding persons with risk for cardiovascular disease.


Subject(s)
Alcoholism/psychology , Metabolic Syndrome/epidemiology , Metabolic Syndrome/psychology , Personality/classification , Type D Personality , Adult , Alcoholism/ethnology , Cardiovascular Diseases/epidemiology , Cross-Sectional Studies , Female , Finland/epidemiology , Humans , Metabolic Syndrome/etiology , Middle Aged
20.
J Stud Alcohol Drugs ; 81(4): 462-470, 2020 07.
Article in English | MEDLINE | ID: mdl-32800082

ABSTRACT

OBJECTIVE: Sexual minority (i.e., lesbian, bisexual) women and racial-ethnic minority groups in the United States are disproportionately harmed by excessive alcohol use. This study examined disparities in excessive alcohol use at the intersection of race-ethnicity and sexual identity for non-Hispanic Black and Hispanic sexual minority women. METHOD: Using data from the 2015 National Survey on Drug Use and Health, we compared the age-adjusted prevalence of binge drinking and heavy alcohol use among sexual minority women of color, sexual minority White women, and heterosexual women of color with that of White heterosexual women. The joint disparity is the difference in the prevalence of excessive alcohol use between sexual minority women of color and White heterosexual women. The excess intersectional disparity is the portion of the joint disparity that is due to being both a racial-ethnic minority and a sexual minority woman. RESULTS: Black and Hispanic sexual minority women reported the highest prevalence of binge drinking (45.4% and 43.4%, respectively), followed by White sexual minority women (35.7%) and White heterosexual women (23%). Black and Hispanic heterosexual women reported the lowest prevalence of binge drinking (20.8% and 20.2%, respectively). The joint disparity in binge drinking between Black sexual minority women and White heterosexual women was 21.2%, and the excess intersectional disparity was 17.7%. The joint disparity in binge drinking between Hispanic sexual minority women and White heterosexual women was 16.8%, and the excess intersectional disparity was 10.8%. CONCLUSIONS: Disparities in excessive alcohol consumption for Black and Hispanic sexual minority women, compared with White heterosexual women, were larger than what would be expected when considering differences by race or sexual identity individually.


Subject(s)
Alcoholism/ethnology , Binge Drinking/ethnology , Bisexuality/statistics & numerical data , Sexual and Gender Minorities/statistics & numerical data , Adolescent , Adult , Black or African American/statistics & numerical data , Aged , Female , Heterosexuality/statistics & numerical data , Hispanic or Latino/statistics & numerical data , Humans , Middle Aged , Minority Groups , United States/epidemiology , Young Adult
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