Subject(s)
Cardiovascular Diseases/ethnology , Antihypertensive Agents/therapeutic use , Asia/ethnology , Cardiac Output, Low/ethnology , Cardiovascular Diseases/prevention & control , Coronary Disease/ethnology , Europe/ethnology , Health Services Accessibility , Humans , Hypertension/drug therapy , Hypertension/ethnology , Myocardial Ischemia/ethnology , Peripheral Vascular Diseases/ethnology , Risk Factors , Stroke/ethnology , West Indies/ethnologyABSTRACT
The neurological observations have been reported at André Bouron Hospital of Saint-Laurent du Maroni and at General Hospital of Cayenne during a period of 5 years. All patients belonged to the "Noir Marron" ethnic group and lived in the area of Saint-Laurent. There were six women and four men, aged 15-35 years. Neurological symptoms were isolated or associated to other organ failure. Neurological manifestations included retrobulbar optic neuropathy, spastic paraparesis, sensitive ataxia and cerebellar ataxia, psychiatric symptoms were observed. Other organs affected were cardiovascular, digestive, cutaneous or endocrinologic (thyroid). Diet consist mainly in cassava. Thiamin deficiency has been observed several times. Improvement of neurological deficits following thiamin administration points towards Thiamin as an etiological factor. Ethnological specificity of Saint-Laurent area may explain that such neurological manifestation have not been observed in the rest of the department.