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2.
Arq. bras. oftalmol ; 84(2): 158-162, Mar,-Apr. 2021. tab, graf
Article in English | LILACS | ID: biblio-1153111

ABSTRACT

ABSTRACT Purpose: The aim of this study was to evaluate the appropriate timing of capsular tension ring implantation in cases of zonular weakness due to pseudoexfoliation syndrome. Methods: This prospective, comparative study was performed at the Ophthalmology Department of Inonu University, Malatya, Turkey. There were 43 patients included in the study. Group 1 (16 patients) had early capsular tension ring implantation, and group 2 (27 patients) had late capsular tension ring implantation. Patients with pseudoexfoliation syndrome who underwent phacoemulsification surgery, posterior chamber intraocular lens implantation, and capsular tension ring implantation were included in the study. Intraoperative complications and difficulties with either capsular tension ring implantation or cortex removal were evaluated in each eye. Results: There was no significant difference between the groups in the difficulty of capsular tension ring implantation (p=0.124). The difficulty of cortex removal differed significantly between the groups (p=0.003). Intraoperative complications were observed in 3 patients in group 1 and 11 patients in group 2; the difference between the groups was not significant (p=0.18). Posterior capsule fluctuations were observed in 8 patients (29.5%) in group 2, which resulted in posterior capsule rupture in 2 patients. Conclusions: Cortex removal is more difficult with early capsular tension ring implantation, and posterior capsule fluctuations may cause problems with late capsular tension ring implantation. The surgeon must consider the risk-to-benefit ratio of early versus late insertion for the optimal timing of capsular tension ring implantation.


RESUMO Objetivo: Avaliar o momento apropriado para implante de anel de tensão capsular em casos de fraqueza zonular devida à síndrome pseudoesfoliativa. Métodos: Este foi um estudo prospectivo e comparativo realizado no Departamento de Oftalmologia da Universidade İnönü. Foram incluídos 43 pacientes, sendo 16 no grupo 1 e 27 no grupo 2. O grupo 1 era composto de pacientes que se submeteram ao implante precoce do anel de tensão capsular, enquanto no grupo 2 os pacientes tiveram implante tardio. Foram incluídos pacientes com síndrome pseudoesfoliativa submetidos à cirurgia de facoemulsificação e ao implante de lente intraocular na câmara posterior e anel de tensão capsular. Em cada olho, foram avaliadas as complicações intraoperatórias e as dificuldades tanto com a implantação do anel de tensão capsular quanto com a remoção do córtex. Resultados: Não houve diferença significativa entre os grupos quanto à dificuldade de implante do anel de tensão capsular (p=0,124). Ao se comparar as remoções do córtex, observou-se diferença significativa entre os grupos (p=0,003). Complicações intraoperatórias foram observadas em 3 pacientes do grupo 1 e 11 pacientes do grupo 2; porém, não houve diferença significativa entre os grupos (p=0,18). No grupo 2, observaram-se flutuações da cápsula posterior em 8 pacientes (29,5%), com ruptura da cápsula posterior em dois deles. Conclusões: A remoção do córtex é mais difícil no implante precoce do anel de tensão capsular e flutuações da cápsula posterior podem causar problemas no implante tardio do anel de tensão capsular. O cirurgião deve ponderar a relação risco/benefício do implante precoce e tardio ao avaliar o momento ideal para implante de anel de tensão capsular.


Subject(s)
Humans , Cataract Extraction/rehabilitation , Phacoemulsification/instrumentation , Cost Efficiency Analysis , Prospective Studies
3.
Acta Ophthalmol ; 98(6): 579-584, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32180359

ABSTRACT

PURPOSE: To describe long-term objective and subjective visual outcomes in a group of Danish children after cataract surgery. METHODS: Follow-up examination of 56 children aged 7-18 years who had undergone uni- or bilateral cataract surgery. Subjective visual function was assessed using the Cardiff Visual Ability Questionnaire for Children (CVAQC) and compared to objective visual acuity for distance and near, contrast vision and stereopsis. RESULTS: Better visual acuity on the better seeing and contrast vision on worst seeing eye were significant predictors of increased subjective visual function in a multivariate analysis, p = 0.024. Children in the unilateral group had a significantly better CVAQC ratio compared to children in the bilateral group, median of 0.88 (range 0.50-1.00) versus 0.80 (range 0.55-0.98), p = 0.027. Reading small print, playing ball games and seeing friends in the playground were the most difficult CVAQC items in the unilateral group and reading small print, seeing the board in the classroom and seeing friends in the playground were the most difficult in the bilateral group. CONCLUSION: Children with unilateral disease often have a healthy eye to support the operated eye, why they overall have better subjective visual function. Many of the most difficult visual tasks were related to academic activities which might hamper future academical capabilities.


Subject(s)
Cataract Extraction/rehabilitation , Visual Acuity , Adolescent , Case-Control Studies , Child , Denmark , Female , Follow-Up Studies , Humans , Male , Surveys and Questionnaires , Vision Tests/methods
4.
J Fr Ophtalmol ; 42(4): 368-374, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30898370

ABSTRACT

PURPOSE: To describe the visual results and postoperative complications of congenital cataract surgeries performed between 2005 and 2016. METHODS: A retrospective consecutive case series of congenital cataract surgeries was carried out at the Dijon University Hospital in France. Intraocular lens implantation was primary or secondary according to age. Pre- and post-operative assessment was performed through ophthalmologic consultations with orthoptic measurements. Visual function and adverse events were recorded. RESULTS: Fifty-six consecutive procedures were evaluated in 37 infants. Overall, 26.8% of patients had unilateral cataracts, and 73.2% had bilateral cataracts. Median age at surgery was 1.0 years [IQR (interquartile range): 0.3-5.2] and 2.7 years [IQR: 0.4-9.5] for unilateral and bilateral cataracts, respectively. Median best-corrected visual acuity (BCVA) at the last follow-up was 0.5logMAR [IQR: 0.2-0.8] and 0.1logMAR [IQR: 0.0-0.8] for the unilateral and bilateral group, respectively. Posterior capsule opacification (PCO) was the primary postoperative complication: 60.0% in unilateral cataract and 46.3% in bilateral cataracts (P=0.019). Median follow-up was 2.0 years [IQR: 1.0-5.0]. CONCLUSION: Congenital cataract surgery appears to be safe and effective when combined with early, conscientious amblyopia treatment. Bilateral congenital cataracts had better visual outcome than unilateral cataract.


Subject(s)
Cataract Extraction , Cataract/congenital , Postoperative Complications/epidemiology , Visual Acuity/physiology , Cataract/complications , Cataract/epidemiology , Cataract/therapy , Cataract Extraction/adverse effects , Cataract Extraction/rehabilitation , Cataract Extraction/statistics & numerical data , Child, Preschool , Female , France/epidemiology , Humans , Infant , Lens Implantation, Intraocular/adverse effects , Lens Implantation, Intraocular/methods , Lens Implantation, Intraocular/statistics & numerical data , Lenses, Intraocular/adverse effects , Male , Postoperative Complications/etiology , Retrospective Studies , Treatment Outcome
5.
J Fr Ophtalmol ; 42(4): 381-386, 2019 Apr.
Article in French | MEDLINE | ID: mdl-30926269

ABSTRACT

PURPOSE: To determine whether phacoemulsification with intraocular lens implantation has a greater impact on the corneal endothelium of type 2 diabetic patients compared to non-diabetic patients. MATERIALS AND METHODS: This study compared the endothelial status in 32 diabetics with good glycemic control and 32 non-diabetic patients before and after uneventful phacoemulsification. Central corneal thickness (CCT), central corneal endothelial cell density (CD), hexagonal cell percentage (HEX), and percent coefficient of variation (% CV) were measured using a specular microscope. RESULTS: Data were matched by age and sex. Diabetics showed a significantly higher loss of endothelial cells compared to non-diabetics. After 3 months, there was a decline of 165 endothelial cells (SD 97) in the diabetic group and 114 (SD 45) in the control group. This was statistically significant (P=0.0065). In addition, diabetics showed a slower recovery trend of endothelial healing as evidenced by a lower CV variation. The CV change was 4.7 in the control group and 3.2 in the diabetic group, which was statistically significant (P=0.023). A significant correlation was found between the energy used and the change in endothelial count as well as the CV in both groups. CONCLUSION: Despite good glycemic control, diabetics have significantly more endothelial damage compared to non-diabetics with a similar nuclear classification and phacoemulsification energy used. This justifies a more careful use of phacoemulsification energy in diabetics.


Subject(s)
Cataract Extraction , Cataract/complications , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/surgery , Endothelium, Corneal/pathology , Lens Implantation, Intraocular , Phacoemulsification , Aged , Blood Glucose/metabolism , Case-Control Studies , Cataract/blood , Cataract Extraction/adverse effects , Cataract Extraction/methods , Cataract Extraction/rehabilitation , Cell Count , Corneal Endothelial Cell Loss/etiology , Diabetes Mellitus, Type 2/blood , Female , Humans , Male , Middle Aged , Phacoemulsification/adverse effects , Phacoemulsification/methods , Phacoemulsification/rehabilitation , Treatment Outcome
6.
Acta Ophthalmol ; 97(2): 173-177, 2019 Mar.
Article in English | MEDLINE | ID: mdl-30242976

ABSTRACT

PURPOSE: The primary goal was to validate a Danish translated version of the Catquest-9SF by Rasch analysis. The secondary goal was to investigate whether preoperative Catquest-9SF scores, best-corrected visual acuity, comorbidity, gender, age or corneal astigmatism could predict improvements in subjective outcome. METHODS: In a prospective trial, 250 patients eligible for cataract surgery were included. Patients filled out the translated Catquest-9SF questionnaire before surgery and again 3 months after surgery. Both preoperative and postoperative questionnaires were included in the Rasch analysis. A multiple reverse stepwise regression model was used to investigate the correlation between preoperative measurements and subjective improvement. RESULTS: The preliminary Rasch analysis showed misfit of items 4 and 6. These items were removed, and the remaining seven items demonstrated a measurement precision of 2.78, a person reliability coefficient of 0.89, ordered response categories, infit of 0.69-1.22, outfit of 0.73-1.14, observed raw variance explained by measures of 70.4% and an eigenvalue of 1.7. Item 7 showed a mild DIF for gender (0.54 logits), and person mean Rasch score targeting was -1.69 logits. Preoperative Catquest score was the only parameter with a significant correlation to a gain in subjective outcome (p < 0.001). A preoperative Catquest-9SF score of 0.5 carried a 95% likelihood of an increase in subjective outcome. CONCLUSION: The Danish version of the Catquest-9SF fit the Rasch model. Only preoperative Catquest-9SF score was correlated to subjective improvement, and a cut-off value of 0.5 predicted an improvement in subjective outcome with 95% probability.


Subject(s)
Cataract Extraction/rehabilitation , Cataract/rehabilitation , Disability Evaluation , Psychometrics/methods , Quality of Life , Surveys and Questionnaires/standards , Visual Acuity , Activities of Daily Living , Aged , Cataract/epidemiology , Denmark/epidemiology , Female , Follow-Up Studies , Humans , Male , Morbidity/trends , Prospective Studies , Reproducibility of Results , Sickness Impact Profile
7.
Humanidades Médicas ; 18(3)set.-dic. 2018.
Article in Spanish | CUMED | ID: cum-75366

ABSTRACT

Se presentan los resultados de la investigación La calidad de vida en pacientes con catarata senil atendidos en Nuevitas de junio a diciembre del 2016, con el objetivo de demostrar el impacto social de la cirugía. Para el estudio descriptivo, longitudinal, prospectivo realizado se seleccionaron 65 pacientes (65 ojos), los cuales constituyen la muestra seleccionada. Para medir el impacto se aplicó una planilla de recolección de datos, y el cuestionario de calidad de vida relativa a la visión (QOLQ-15) pre y postoperatoria. Se concluye que todos los pacientes fueron operados debido a un deterioro visual y funcional marcado. Luego de la cirugía se logró una recuperación visual satisfactoria, con una mejor calidad de vida que revela valores altamente significativos desde el punto de vista clínico, psicológico y social que contribuyeron a la reincorporación de estos ancianos a la sociedad(AU)


It is presented the results of the investigation “The quality of life in patients with senile cataract attended in Nuevitas from June to December, 2016", with the objective to demonstrate the social impact of the surgery. For the descriptive, longitudinal, pilot study were selected 65 patients (65 eyes), which constitute the chosen sample. To measure the impact there was applied a chart of information compilation, and the questionnaire of quality of life relative to the vision (QOLQ-15) pre and postoperative. It was concluded that all the patients were operated due to a pronounced visual and functional deterioration. After the surgery a satisfactory visual recovery was achieved, with a better quality of life that reveals highly significant values from the clinical, psychological and social point of view that they contributed to the reincorporation of these elders to the society(AU)


Subject(s)
Humans , Aged , Cataract Extraction/rehabilitation , Quality of Life , Eye Health , Epidemiology, Descriptive , Longitudinal Studies , Prospective Studies
8.
J Glaucoma ; 27(7): 622-626, 2018 07.
Article in English | MEDLINE | ID: mdl-29750722

ABSTRACT

PURPOSE: To evaluate a novel gonioscopy score as a potential predictor for intraocular pressure (IOP) reduction after cataract surgery. MATERIALS AND METHODS: This was a prospective study that included consecutive patients with or without glaucoma, either with open or narrow angles but without peripheral anterior synechiae, who underwent phacoemulsification. Eyes with intraoperative complications and secondary glaucoma were excluded. A preoperative gonioscopy score was created, summing the Shaffer gonioscopy grading in 4 quadrants (range, 0 to 16). To determine variables associated with IOP change at 6 months, univariate and multivariate linear mixed-effects regression analysis was performed adjusting for age, sex, and preoperative IOP. RESULTS: In total, 188 eyes from 137 patients were enrolled. The mean age of the patients was 75.0 (±8.5) years and the average preoperative IOP was 15.6 (±3.6) mm Hg with 0.7 (range, 0 to 4) glaucoma medications. The mean IOP reduction after phacoemulsification was 3.0 (±2.6) mm Hg at postoperative month 6. After multivariate analysis, preoperative IOP [ß=0.49 (0.41-0.58), P<0.0001], gonioscopy score [ß=-0.17 (-0.24 to -0.09), P<0.0001], anterior chamber depth (ACD) [ß=-0.88 (-1.64 to -0.14), P=0.02], and IOP/ACD ratio [ß=0.45 (0.07 to 0.83) P=0.021] were associated with IOP reduction at 6 months. CONCLUSIONS: Preoperative predictors for IOP reduction after cataract surgery were preoperative IOP, ACD, gonioscopy score, and IOP/ACD ratio. The IOP/ACD ratio and gonioscopy score can be easy parameters to obtain and may help clinicians to estimate the IOP reduction after phacoemulsification.


Subject(s)
Cataract Extraction , Cataract/diagnosis , Glaucoma/diagnosis , Glaucoma/surgery , Gonioscopy , Phacoemulsification , Aged , Aged, 80 and over , Cataract/complications , Cataract/physiopathology , Cataract Extraction/methods , Cataract Extraction/rehabilitation , Female , Glaucoma/complications , Glaucoma/physiopathology , Gonioscopy/methods , Humans , Intraocular Pressure/physiology , Male , Middle Aged , Phacoemulsification/methods , Phacoemulsification/rehabilitation , Postoperative Period , Prognosis , Prospective Studies , Research Design , Tonometry, Ocular , Treatment Outcome , Visual Acuity
9.
J Glaucoma ; 27(7): 600-605, 2018 07.
Article in English | MEDLINE | ID: mdl-29757810

ABSTRACT

PURPOSE: The aims of this study were to observe the changes in the demand for prescriptions of ocular hypertensive drug (OHD) after cataract surgery, to investigate patterns of change in the required OHD amount in open-angle glaucoma (OAG) and angle-closure glaucoma (ACG) cases, and to determine the associated factors related to the change. MATERIALS AND METHODS: This population-based cohort study using the Taiwan National Health Insurance Research Database enrolled patients with glaucoma who underwent bilateral cataract surgeries within 2 years between 2001 and 2012. The major dependent variables were the total amounts of OHDs prescribed within 1 year before the first cataract surgery and 1 year after the second cataract surgery. We compared the overall change in the required OHD amount before and after cataract surgery and further explored potential factors affecting the change. RESULTS: Among the 440 patients, there were more cases of ACG than OAG (68.6% vs. 31.4%). The total OHD amount prescribed reduced significantly after cataract surgery in patients with OAG (median, from 12 to 6 bottles before and after the surgery, P<0.0001) and ACG (median, from 10 to 3 bottles, P<0.0001), and the reduction was sustained for 5 years. The reduction was significantly larger in patients with ACG and higher demand for OHD (P=0.0157). Among the OAG cases, the reduction was significantly larger in patients who were female individuals (P=0.0138), treated in clinics (P=0.0305), and exhibited high demand for OHD (P=0.0282). CONCLUSIONS: The prescriptions of OHDs by glaucoma patients reduced considerably after cataract surgery. Although the reduction proportion of the demand for OHD after cataract surgery was significantly larger in patients with ACG than in those with OAG, the reduction was sustained for 5 years in both types of glaucoma.


Subject(s)
Antihypertensive Agents/therapeutic use , Cataract Extraction/statistics & numerical data , Cataract/epidemiology , Glaucoma/drug therapy , Glaucoma/epidemiology , Aged , Antihypertensive Agents/pharmacology , Cataract/complications , Cataract/drug therapy , Cataract Extraction/adverse effects , Cataract Extraction/rehabilitation , Cohort Studies , Female , Glaucoma/complications , Glaucoma/surgery , Humans , Intraocular Pressure/drug effects , Longitudinal Studies , Male , Middle Aged , Practice Patterns, Physicians'/statistics & numerical data , Retrospective Studies , Taiwan/epidemiology
10.
Acta Ophthalmol ; 96(6): 582-585, 2018 Sep.
Article in English | MEDLINE | ID: mdl-29461682

ABSTRACT

PURPOSE: To explore the relationship between acquisition of new spectacles after routine cataract surgery and vision-related activity limitation (VRAL) postoperatively. METHODS: This cohort study with intervention (survey) included 1329 patients in Sweden who had undergone a second-eye cataract surgery during March 2013. Data from the Swedish National Cataract Register were used, including evaluations of VRAL through the Catquest-9SF questionnaire before and 3 months after cataract surgery. Five months after the second-eye surgery, patients completed another five-item questionnaire about spectacle use preoperatively and postoperatively including an item on surgeons' advice about the need for spectacles. These responses were linked to the Rasch-analysed Catquest-9SF data to identify correlations with VRAL. RESULTS: A total of 1239 patients finally participated in the study after excluding those who did not fulfil the inclusion criteria. Patients who were advised about the need for spectacles postoperatively (n = 387) had a greater (p = 0.039) improvement in the postoperative VRAL compared to patients who were not advised (n = 691). Patients who obtained new spectacles postoperatively (n = 512) also had greater improvement (p = 0.032) compared to those who did not (n = 724). CONCLUSION: The average improvements in the VRAL after surgery were significantly higher for patients who obtained new distance spectacles postoperatively and for patients who were informed about the need for spectacles by their practitioners.


Subject(s)
Activities of Daily Living , Cataract Extraction/rehabilitation , Eyeglasses/statistics & numerical data , Patient Satisfaction , Refractive Errors/rehabilitation , Visual Acuity , Aged , Disability Evaluation , Female , Humans , Male , Postoperative Period , Quality of Life , Refractive Errors/etiology , Refractive Errors/physiopathology , Surveys and Questionnaires
11.
Indian J Ophthalmol ; 65(12): 1294-1300, 2017 Dec.
Article in English | MEDLINE | ID: mdl-29208809

ABSTRACT

Modern day cataract surgery is evolving from a visual restorative to a refractive procedure. The advent of multifocal intraocular lenses (MFIOLs) allows greater spectacle independence and increased quality of life postoperatively. Since the inception in 1980s, MFIOLs have undergone various technical advancements including trifocal and extended depth of vision implants more recently. A thorough preoperative workup including the patients' visual needs and inherent ocular anatomy allows us to achieve superior outcomes. This review offers a comprehensive overview of the various types of MFIOLs and principles of optimizing outcomes through a comprehensive preoperative screening and management of postoperative complications.


Subject(s)
Cataract Extraction/rehabilitation , Multifocal Intraocular Lenses , Patient Satisfaction , Presbyopia/therapy , Visual Acuity , Humans , Presbyopia/etiology , Presbyopia/physiopathology , Prosthesis Design , Quality of Life
12.
J Fr Ophtalmol ; 40(8): 629-635, 2017 Oct.
Article in French | MEDLINE | ID: mdl-28882390

ABSTRACT

INTRODUCTION: Our goal is to assess the Quality of Life (QL) of our patients after cataract surgery. MATERIALS AND METHODS: We performed a multicenter prospective study from July 2012 to December 2013 including patients undergoing cataract surgery, aged 18 and older. A survey sheet with sociodemographic data, clinical data and QL survey (VF-14) was given to each patient after surgery at day 7 (D7), one month (M1) and two months (M2) postoperatively. The final score was obtained by the following formula: QL=V (%)=(F __/__ C)×25. The data analysis was performed using SPSS software. RESULTS: A total of 100 patients were included, 56 men, and 61 years was the mean age. The mean QL score was 29.86% at D7, 73.97% at M1 and 81.21% at M2. Subjects between 18 and 30 years of age had a score of 90.15% vs. 82.52% at M2 for older patients. After optical correction, the quality of life scores increased from 83.22% at D7 to 93.18% at M2. Patients who did not have functional signs had a QL score of 83.94%. Anxious patients had a QL score of 44% at D7, 61.23% at M1 and 52.67% at M2. CONCLUSION: Good surgical outcomes require, in addition to clinical success, good quality of life. Several factors may influence this quality of life.


Subject(s)
Cataract Extraction/rehabilitation , Quality of Life , Adult , Aged , Aged, 80 and over , Cataract Extraction/psychology , Female , Humans , Male , Middle Aged , Postoperative Period , Surveys and Questionnaires , Vision, Ocular/physiology , Visual Acuity/physiology
13.
Adv Ther ; 34(8): 1815-1839, 2017 08.
Article in English | MEDLINE | ID: mdl-28674958

ABSTRACT

INTRODUCTION: Refractive surgery in presbyopia tends to achieve spectacle independence with minimal optical disturbances. We compared monovision to multifocality procedures regarding these outcomes. METHODS: We conducted a systematic review of published (till November 21, 2016) randomized controlled trials (RCTs) comparing any monovision to any multifocality method or comparing different monovision/multifocality methods to each other that enabled direct or indirect comparisons between particular monovision and particular multifocality procedures in presbyopic patients undergoing cataract-related or unrelated surgery in respect to spectacle independence, unaided binocular visual acuity (VA), contrast sensitivity (CS), and adverse events. RESULTS: Three trials comparing monovision (monofocal lenses, LASIK) to multifocal intraocular lenses (MFIOLs; Isert refractive or Tecnis diffractive) and 6 comparing other MFIOLs to Tecnis were included (1-12 months duration). Spectacle independence. All reporting trials were of sufficient quality. Directly, pseudophakic monovision was inferior to Isert (1 trial, N = 75, RR = 0.49, 95% CI 0.28-0.80) and Tecnis (1 trial, N = 211, RR = 0.36, 95% CI 0.25-0.52) in cataract patients, and LASIK was comparable to Tecnis (1 trial, N = 100, RR = 0.93, 0.78-1.10) in refractive surgery. In network meta-regression (6 trials, 14 arms) pseudophakic monovision in cataract patients was inferior to Tecnis. Indirect data suggest also that it is inferior (ReZoom refractive, TwinSet diffractive) or tends to be inferior (Array refractive) to other MFIOLs. LASIK was comparable to Tecnis in refractive surgery. Indirect data suggest also that it tends to superiority vs. ReZoom or Array refractive MFIOLs. Adverse events. No pooling was possible (heterogeneity of assessment and reporting). One quality direct RCT indicated less glare/dazzle with pseudophakic monovision vs. Tecnis in cataract patients. Unaided VA and CS data were burdened with heterogeneity (assessment, reporting) and insufficient quality. CONCLUSIONS: Randomized comparisons of monovision to multifocality are scarce. Existing estimates regarding spectacle independence (imprecision, indirectness) and particularly regarding unaided VA and CS (assessment/reporting heterogeneity, bias, imprecision, indirectness) are burdened with uncertainty. Dysphotopsia is less common with monovision, but estimate uncertainty is high (bias, imprecision).


Subject(s)
Cataract Extraction/rehabilitation , Lens Implantation, Intraocular , Multifocal Intraocular Lenses , Visual Acuity/physiology , Contrast Sensitivity , Eyeglasses , Humans , Male , Postoperative Period , Presbyopia , Randomized Controlled Trials as Topic
14.
J Fr Ophtalmol ; 40(6): 487-498, 2017 Jun.
Article in French | MEDLINE | ID: mdl-28571835

ABSTRACT

OBJECTIVE: Cataract surgery for 50 Alzheimer patients (55 eyes). METHODS: Cinquante Alzheimer's patients with 0≤MMS≤25, with bilateral disabling cataracts were included for surgery. The surgical technique is analyzed. RESULTS AND CONCLUSION: The preoperative examination of Alzheimer's patients is time consuming and requires experience in this area, which is important to integrate into the practice of ophthalmology. The type of cataract is unusual, with a predilection for pseudoexfoliation syndrome and zonular fragility that has to be managed during surgery. The procedure may be performed under local anesthesia. Three months after surgery, Alzheimer's patients demonstrated improved visual acuity (P<0.001) with no worsening of their dementia.


Subject(s)
Alzheimer Disease/surgery , Cataract Extraction , Cataract/complications , Aged , Aged, 80 and over , Alzheimer Disease/complications , Cataract Extraction/rehabilitation , Exfoliation Syndrome/surgery , Female , Humans , Intraoperative Complications/etiology , Life Style , Male , Postoperative Complications/etiology , Visual Acuity
15.
Cochrane Database Syst Rev ; 12: CD003169, 2016 12 12.
Article in English | MEDLINE | ID: mdl-27943250

ABSTRACT

BACKGROUND: Good unaided distance visual acuity (VA) is now a realistic expectation following cataract surgery and intraocular lens (IOL) implantation. Near vision, however, still requires additional refractive power, usually in the form of reading glasses. Multiple optic (multifocal) IOLs are available which claim to allow good vision at a range of distances. It is unclear whether this benefit outweighs the optical compromises inherent in multifocal IOLs. OBJECTIVES: To assess the visual effects of multifocal IOLs in comparison with the current standard treatment of monofocal lens implantation. SEARCH METHODS: We searched CENTRAL (which contains the Cochrane Eyes and Vision Trials Register) (2016, Issue 5), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to June 2016), Embase (January 1980 to June 2016), the ISRCTN registry (www.isrctn.com/editAdvancedSearch), ClinicalTrials.gov (www.clinicaltrials.gov), and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 13 June 2016. SELECTION CRITERIA: All randomised controlled trials comparing a multifocal IOL of any type with a monofocal IOL as control were included. Both unilateral and bilateral implantation trials were included. We also considered trials comparing multifocal IOLs with "monovision" whereby one eye is corrected for distance vision and one eye corrected for near vision. DATA COLLECTION AND ANALYSIS: We used standard methodological procedures expected by Cochrane. We assessed the 'certainty' of the evidence using GRADE. MAIN RESULTS: We found 20 eligible trials that enrolled 2230 people with data available on 2061 people (3194 eyes). These trials were conducted in Europe (13), China (three), USA (one), Middle East (one), India (one) and one multicentre study in Europe and the USA. Most of these trials compared multifocal with monofocal lenses; two trials compared multifocal lenses with monovision. There was considerable variety in the make and model of lenses implanted. Overall we considered the trials at risk of performance and detection bias because it was difficult to mask participants and outcome assessors. It was also difficult to assess the role of reporting bias.There was moderate-certainty evidence that the distance acuity achieved with multifocal lenses was not different to that achieved with monofocal lenses (unaided VA worse than 6/6: pooled RR 0.96, 95% confidence interval (CI) 0.89 to 1.03; eyes = 682; studies = 8). People receiving multifocal lenses may achieve better near vision (RR for unaided near VA worse than J3/J4 was 0.20, 95% CI 0.07 to 0.58; eyes = 782; studies = 8). We judged this to be low-certainty evidence because of risk of bias in the included studies and high heterogeneity (I2 = 93%) although all included studies favoured multifocal lenses with respect to this outcome.People receiving multifocal lenses may be less spectacle dependent (RR 0.63, 95% CI 0.55 to 0.73; eyes = 1000; studies = 10). We judged this to be low-certainty evidence because of risk of bias and evidence of publication bias (skewed funnel plot). There was also high heterogeneity (I2 = 67%) but all studies favoured multifocal lenses. We did not additionally downgrade for this.Adverse subjective visual phenomena were more prevalent and more troublesome in participants with a multifocal IOL compared with monofocals (RR for glare 1.41, 95% CI 1.03 to 1.93; eyes = 544; studies = 7, low-certainty evidence and RR for haloes 3.58, 95% CI 1.99 to 6.46; eyes = 662; studies = 7; moderate-certainty evidence).Two studies compared multifocal lenses with monovision. There was no evidence for any important differences in distance VA between the groups (mean difference (MD) 0.02 logMAR, 95% CI -0.02 to 0.06; eyes = 186; studies = 1), unaided intermediate VA (MD 0.07 logMAR, 95% CI 0.04 to 0.10; eyes = 181; studies = 1) and unaided near VA (MD -0.04, 95% CI -0.08 to 0.00; eyes = 186; studies = 1) compared with people receiving monovision. People receiving multifocal lenses were less likely to be spectacle dependent (RR 0.40, 95% CI 0.30 to 0.53; eyes = 262; studies = 2) but more likely to report problems with glare (RR 1.41, 95% CI 1.14 to 1.73; eyes = 187; studies = 1) compared with people receiving monovision. In one study, the investigators noted that more people in the multifocal group underwent IOL exchange in the first year after surgery (6 participants with multifocal vs 0 participants with monovision). AUTHORS' CONCLUSIONS: Multifocal IOLs are effective at improving near vision relative to monofocal IOLs although there is uncertainty as to the size of the effect. Whether that improvement outweighs the adverse effects of multifocal IOLs, such as glare and haloes, will vary between people. Motivation to achieve spectacle independence is likely to be the deciding factor.


Subject(s)
Cataract Extraction/rehabilitation , Lenses, Intraocular , Visual Acuity/physiology , Adult , Contrast Sensitivity/physiology , Humans , Lenses, Intraocular/psychology , Patient Satisfaction , Prosthesis Design , Randomized Controlled Trials as Topic , Vision, Ocular/physiology
17.
Klin Monbl Augenheilkd ; 233(8): 923-7, 2016 Aug.
Article in German | MEDLINE | ID: mdl-27385257

ABSTRACT

PURPOSE: Evaluation of the visual and refractive results 3 months after implantation of a diffractive extended range of vision (ERV) intraocular lens (IOL) during cataract surgery. METHODS: In a prospective multicentre study, patients with a calculated postoperative corneal astigmatism of ≤ 1.5 D received a diffractive ERV IOL (TECNIS Symfony, model ZXR00, Abbott Medical Optics, USA) during cataract surgery. After 3 months, the monocular and binocular corrected and uncorrected far, intermediate and near visual acuity, as well as refraction, were evaluated. RESULTS: 18 patients (36 eyes) with a mean age of 63.34 ± 4.6 years underwent bilateral cataract surgery. After 3 months, the binocular uncorrected distance visual acuity (UDVA) of logMAR was - 0.05 ± 0.11 and the corrected distance visual acuity (CDVA) of logMAR - 0.14 ± 0.05. Binocular uncorrected intermediate (UIVA) and near visual acuity (UNVA) were logMAR - 0.09 ± 0.02 and 0.19 ± 0.09, respectively. A target refraction of ± 0.75 D was reached by 89 % of the patients. CONCLUSION: Implantation of an extended range of vision intraocular lens offers an effective way for visual rehabilitation at far and intermediate distances. Near vision is still in a functional range.


Subject(s)
Cataract Extraction/rehabilitation , Lens Implantation, Intraocular , Lenses, Intraocular , Recovery of Function , Refractive Errors/diagnosis , Refractive Errors/rehabilitation , Adult , Cataract Extraction/adverse effects , Equipment Failure Analysis , Female , Follow-Up Studies , Germany , Humans , Longitudinal Studies , Male , Prosthesis Design , Refractive Errors/etiology , Treatment Outcome , Visual Acuity
18.
Klin Monbl Augenheilkd ; 233(5): 633-8, 2016 May.
Article in German | MEDLINE | ID: mdl-27187885

ABSTRACT

PURPOSE: Evaluation of the clinical data 3 months after implantation of a new diffractive multifocal intraocular lens (MIOL) with a reduced near add power of + 2.75 D. METHODS: In a prospective study, patients who underwent cataract surgery or refractive lens exchange with implantation of an MIOL (Tecnis ZKB00, Abbott Medical Optics, Santa Ana, California, USA) were included. Three months postoperative corrected and uncorrected visual acuities at different distances were measured and evaluated. Those patients that underwent bilateral MIOL implantation additionally filled out a questionnaire 3 months postoperatively. RESULTS: Between October 2013 and August 2014, 115 eyes of 62 patients were implanted with the ZKB00 IOL. Mean postoperative refractions were - 0.27 ± 0.44 D for the spherical equivalent, respectively. Mean binocular CDVA was - 0.01 ± 0.3 logMAR with a mean binocular UDVA of 0.06 ± 0.08 logMAR. For near distance in 40 cm, an UNVA of 0.07 ± 0.10 logMAR three months postoperatively was measured. CONCLUSION: The ZKB00 IOL belongs to a group of novel MIOL with an increased intermediate visual performance. Our study shows good visual acuity at all distances, as well as a high rate of satisfaction and subjectively good image quality.


Subject(s)
Cataract Extraction/adverse effects , Cataract Extraction/rehabilitation , Lens Implantation, Intraocular , Lenses, Intraocular/classification , Refractive Errors/etiology , Refractive Errors/therapy , Aged , Aged, 80 and over , Equipment Failure Analysis , Female , Humans , Male , Middle Aged , Prospective Studies , Prosthesis Design , Refractive Errors/diagnosis , Treatment Outcome , Visual Acuity
20.
Acta Ophthalmol ; 94 Suppl 2: 1-34, 2016 Apr.
Article in English | MEDLINE | ID: mdl-27111408

ABSTRACT

Cataract surgery is the most common ophthalmological surgical procedure, and it is predicted that the number of surgeries will increase significantly in the future. However, little is known about the recovery after surgery. The first aim of this study was to evaluate the prevalence, severity and duration of pain and other ocular discomfort symptoms experienced after cataract surgery. The other objectives were to identify the factors associated with lower postoperative patient satisfaction and to measure the effect of cataract surgery on patients' health-related quality of life (HRQoL) and visual function in everyday life. The study design was a prospective follow-up study. The course of the recovery and the presence of ocular symptoms were evaluated by interviewing the patients via a questionnaire at 1 day, 1 week, 6 weeks and one year after surgery The visual functioning in everyday life was measured with Visual Functioning Index VF-7 and Catquest-9SF-questionnaires and furthermore the HRQoL was measured with the 15D-instrument before surgery and at 12 months after surgery. The patients returned the questionnaires by mail and were interviewed in the hospital on the day of the surgery. The same patients filled-in all the questionnaires. The patient reports were used to collect the data on medical history. A total of 303 patients were approached at Kuopio University Hospital in 2010-2011 and of these 196 patients were eligible and willing to participate, with postoperative data being available from 186 (95%) patients. A systematic review article was included in the study procedure and it revealed the wide range in the reported incidence of postoperative ocular pain. Some of the identified randomized controlled studies reported no or only minor pain whereas in some studies significant pain or pain lasting for several weeks has been described in more than 50% of the study patients. In the present study setting, pain was reported by 34% during the first postoperative hours and by approximately 10% of patients during the first six weeks after surgery. During the early recovery in the hospital, only a minority of the patients reporting pain were provided with pain medication. The ocular discomfort symptoms such as itchiness, burning, foreign-body sensation and tearing were common both before (54%) and after surgery (38-52%). These symptoms can also be described as painful symptoms and are often difficult to distinguish from ocular pain. The symptoms are also typical of ocular surface disease, and some patients may benefit from the postoperative administration of tear substitutes. The patients reporting postoperative ocular symptoms were less satisfied with the treatment outcome at 12 months after surgery (p = 0.001) compared to the patients who experienced no symptoms. Those patients reporting less disability in visual functioning before surgery were more satisfied than patients with more reported disability. The HRQoL improved significantly after cataract surgery (p = 0.002). However, when compared to an age-and gender-standardized control population, in cataract subjects the HRQoL remained slightly worse both before and at 12 months after surgery.


Subject(s)
Cataract Extraction/rehabilitation , Pain, Postoperative/drug therapy , Patient Satisfaction , Quality of Life , Visual Acuity , Adult , Aged , Aged, 80 and over , Cataract Extraction/adverse effects , Female , Follow-Up Studies , Humans , Lens Implantation, Intraocular , Male , Middle Aged , Pain Measurement , Pain, Postoperative/etiology , Postoperative Period , Surveys and Questionnaires , Treatment Outcome , Vision, Ocular
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