ABSTRACT
BACKGROUND: Poly-l-lactic acid (PLLA) is an injectable volumizer with biostimulatory properties used for volumetric structural rejuvenation in patients with facial fat volume loss but has increasingly been utilized for off-face applications. OBJECTIVE: The objectives of this randomized, double-blind, placebo-controlled single center study was to assess the safety and effectiveness of PLLA for the treatment of lower extremity cellulite in adult women. METHODS: 31 healthy women were enrolled in the study. Eligible subjects received 3 treatments every 4 weeks with either PLLA (treatment group) or saline (control group) injections combined with subcision, into each of the glutes or thighs. Follow-up visits were at 1, 3, and 6 months after treatment. Assessments included live ratings, rating of standardized pictures by a blinded evaluator, patient questionnaires, safety, and tolerability ratings. RESULTS: At the 3 and 6-month follow-up, there was a statistically significant change in the global aesthetic improvement scale (GAIS) compared to baseline as assessed by blinded investigators. Significant improvements were shown in the cellulite severity scale (CSS) as well as in the subject satisfaction questionnaires. Treatments were found to be tolerable, and no severe treatment-related adverse events occurred. CONCLUSION: Repeated PLLA treatments combined with subcision are effective and safe in improving the appearance of cellulite. J Drugs Dermatol. 20(5): doi:10.36849/JDD.5380.
Subject(s)
Cellulite/drug therapy , Cellulose/administration & dosage , Cosmetic Techniques/adverse effects , Lactic Acid/administration & dosage , Mannitol/administration & dosage , Patient Satisfaction , Adult , Cellulite/diagnosis , Cellulite/psychology , Cellulose/adverse effects , Double-Blind Method , Esthetics , Female , Follow-Up Studies , Humans , Injections, Subcutaneous , Lactic Acid/adverse effects , Lower Extremity , Mannitol/adverse effects , Placebos/administration & dosage , Placebos/adverse effects , Severity of Illness Index , Surveys and Questionnaires/statistics & numerical data , Treatment OutcomeABSTRACT
En este artículo se presenta un instrumento que evalúa la imagen corporal y los síntomas del Trastorno Dismórfico, la versión de auto-informe del Body Dysmorphic Disorder Examination (BDDE-C; Examen del Trastorno Dismórfico Corporal) de Reiter y Rosen (2000). El objetivo de nuestra investigación fue validar dicha entrevista en una muestra de población española. Para ello se administraron diferentes cuestionarios a una muestra de sujetos pertenecientes a población general y otra muestra de usuarias de centros de estética. Se realizaron los siguientes análisis de resultados: análisis factorial, correlación con otros instrumentos de medida, fiabilidad test-retest y comparación de medias en función de distintas variables. Además, se analiza el nivel de insatisfacción corporal en general y para cada una de las partes del cuerpo, tanto en hombres como en mujeres (AU)
