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1.
PLoS One ; 19(5): e0303268, 2024.
Article in English | MEDLINE | ID: mdl-38768176

ABSTRACT

The Experience of Embodiment Scale (EES) is a recently developed instrument that assesses experiences of living in the body. Here, we prepared a novel Greek translation of the EES and examined its psychometric properties. We initially prepared a Greek translation of the EES using a 5-step procedure recommended for test adaptation studies. Next, in a cross-sectional study, we asked a sample of 933 women from Cyprus to complete the Greek EES, alongside additional, previously validated measures assessing body appreciation, psychological well-being (self-esteem, life satisfaction), eating restriction, perfectionism, and internalisation of appearance ideals. Our analyses showed that EES factorial models based on confirmatory factor analysis (CFA) roundly had poor fit. Conversely, models based on exploratory structural equation modelling (ESEM)-which accounts for the fact that EES items cross-load across factors-had adequate fit to the data. Additionally, we found that both higher-order and bifactor-ESEM models that controlled for the uniqueness of negatively worded items had adequate fit. The bifactor-ESEM model had the best fit of all the models tested, and was invariant across ethnicity (Greeks and Greek-Cypriots) and was unaffected by differential item functioning based on age and body mass index. Additionally, construct validity of the final, optimal model was adequate, especially for its G-factor, as indicated by significant associations with additional constructs in expected directions. These results suggest that a bifactor-ESEM model of the Greek EES has adequate psychometric properties. Our work highlights important psychometric issues relating to the manner in which the EES should (or could) be conceptualised and modelled, which should be considered more fully in future work.


Subject(s)
Psychometrics , Humans , Female , Cyprus , Psychometrics/methods , Adult , Middle Aged , Cross-Sectional Studies , Surveys and Questionnaires , Self Concept , Young Adult , Factor Analysis, Statistical , Body Image/psychology , Personal Satisfaction , Adolescent
2.
Proc Natl Acad Sci U S A ; 121(21): e2318293121, 2024 May 21.
Article in English | MEDLINE | ID: mdl-38753504

ABSTRACT

The antiquity of human dispersal into Mediterranean islands and ensuing coastal adaptation have remained largely unexplored due to the prevailing assumption that the sea was a barrier to movement and that islands were hostile environments to early hunter-gatherers [J. F. Cherry, T. P. Leppard, J. Isl. Coast. Archaeol. 13, 191-205 (2018), 10.1080/15564894.2016.1276489]. Using the latest archaeological data, hindcasted climate projections, and age-structured demographic models, we demonstrate evidence for early arrival (14,257 to 13,182 calendar years ago) to Cyprus and predicted that large groups of people (~1,000 to 1,375) arrived in 2 to 3 main events occurring within <100 y to ensure low extinction risk. These results indicate that the postglacial settlement of Cyprus involved only a few large-scale, organized events requiring advanced watercraft technology. Our spatially debiased and Signor-Lipps-corrected estimates indicate rapid settlement of the island within <200 y, and expansion to a median of 4,000 to 5,000 people (0.36 to 0.46 km-2) in <11 human generations (<300 y). Our results do not support the hypothesis of inaccessible and inhospitable islands in the Mediterranean for pre-agropastoralists, agreeing with analogous conclusions for other parts of the world [M. I. Bird et al., Sci. Rep. 9, 8220 (2019), 10.1038/s41598-019-42946-9]. Our results also highlight the need to revisit these questions in the Mediterranean and test their validity with new technologies, field methods, and data. By applying stochastic models to the Mediterranean region, we can place Cyprus and large islands in general as attractive and favorable destinations for paleolithic peoples.


Subject(s)
Archaeology , Humans , Cyprus , Archaeology/methods , History, Ancient , Human Migration/history , Demography/methods
3.
Rev Lat Am Enfermagem ; 32: e4173, 2024.
Article in English, Spanish, Portuguese | MEDLINE | ID: mdl-38695430

ABSTRACT

OBJECTIVE: the aim of this study is to investigate the relationship between death distress, psychological adjustment, optimism, pessimism and perceived stress among nurses working during the COVID-19 pandemic. METHOD: this study was designed as cross-sectional/cohort. The population of the study involved 408 nurses from Northern Cyprus, which are registered as full members of the Nurse Council. The sample comprised 214 nurses, who volunteered to participate in the study. The study data was collected using a web-based online survey (Demographic form, the Coronavirus Stress Measure, The Optimism and Pessimism Questionnaire, The Brief Adjustment Scale-6, The Death Distress Scale). RESULTS: the results indicated that perceived stress significantly and negatively predicted optimism (ß = -0.21, p < 0.001) and pessimism (ß = 0.38, p < 0.001). Perceived stress had significant and positive predictive effects on psychological adjustment (ß = 0.31, p < 0.001) and death distress (ß = 0.17, p < 0.01). Further analysis results revealed that pessimism mediates the association of stress with psychological adjustment and death distress; however, optimism only mediates the effect of stress on psychological adjustment among nurses. CONCLUSION: a low level of pessimism is effective in strengthening nurses' psychological adjustment skills againt perceived stress and death distress. Nurses should consider behavioral strategies to help reduce the level of pessimism during periods such as pandemics. BACKGROUND: (1) High levels of perceived stress increased higher score of psychological adjustment. (2) Pessimism mediates the association of stress with adjustment and death distress. (3) Optimism only mediates the effect of stress on psychological adjustment among nurses.


Subject(s)
COVID-19 , Optimism , Pandemics , Pessimism , Humans , COVID-19/psychology , COVID-19/epidemiology , Cross-Sectional Studies , Optimism/psychology , Female , Adult , Male , Pessimism/psychology , Middle Aged , Emotional Adjustment , Nurses/psychology , Cyprus , Attitude to Death , Adaptation, Psychological , Cohort Studies , Stress, Psychological/epidemiology , Stress, Psychological/psychology , Psychological Distress , SARS-CoV-2 , Surveys and Questionnaires , Young Adult
5.
Sci Rep ; 14(1): 9632, 2024 04 26.
Article in English | MEDLINE | ID: mdl-38671010

ABSTRACT

Archaeological evidence supports sporadic seafaring visits to the Eastern Mediterranean island of Cyprus by Epipaleolithic hunter-gatherers over 12,000 years ago, followed by permanent settlements during the early Neolithic. The geographical origins of these early seafarers have so far remained elusive. By systematically analysing all available genomes from the late Pleistocene to early Holocene Near East (c. 14,000-7000 cal BCE), we provide a comprehensive overview of the genetic landscape of the early Neolithic Fertile Crescent and Anatolia and infer the likely origins of three recently published genomes from Kissonerga-Mylouthkia (Cypriot Late Pre-Pottery Neolithic B, c. 7600-6800 cal BCE). These appear to derive roughly 80% of their ancestry from Aceramic Neolithic Central Anatolians residing in or near the Konya plain, and the remainder from a genetically basal Levantine population. Based on genome-wide weighted ancestry covariance analysis, we infer that this admixture event took place roughly between 14,000 and 10,000 BCE, coinciding with the transition from the Cypriot late Epipaleolithic to the Pre-Pottery Neolithic A (PPNA). Additionally, we identify strong genetic affinities between the examined Cypro-LPPNB individuals and later northwestern Anatolians and the earliest European Neolithic farmers. Our results inform archaeological evidence on prehistoric demographic processes in the Eastern Mediterranean, providing important insights into early seafaring, maritime connections, and insular settlement.


Subject(s)
Archaeology , Cyprus , Humans , Human Migration/history , Genome, Human , History, Ancient , DNA, Ancient/analysis , Genetics, Population
6.
Nutrients ; 16(8)2024 Apr 21.
Article in English | MEDLINE | ID: mdl-38674928

ABSTRACT

Associations between subjective well-being (SWB) and dietary habits, employment status, and habitual activities are increasingly capturing the focus of researchers as well as policymakers worldwide. This study aimed to explore these associations in a sample of the population in Greece and Cyprus via an online survey. In total, 936 questionnaires (470: Cyprus, 466: Greece) were analyzed to study the associations between the Mediterranean Diet (MD) (using the 14-item MEDAS score, (14-MEDAS)), subjective well-being (SWB), and several socioeconomic factors. Key remarks of this survey highlight the positive impact of MD adherence on some well-being items. Namely, statistically significant differences were found on the following items: Satisfied with life (p < 0.001), Life worthwhile (p < 0.001), Feeling happy (p < 0.001), worried (p = 0.005), and depressed (p = 0.001), when comparing Low MD adherence (14-MEDAS < 5) to High MD adherence (14-MEDAS > 10). Other lifestyle habits such as spending time with friends and family, spending time in nature, and habitual physical activity were associated with aspects of SWB such as Life satisfaction, Life worthwhile, Feeling happy, and energetic. The findings support adherence to the MD, since it is associated with higher life satisfaction and self-reported happiness in this sample and should be considered when developing health policies on well-being.


Subject(s)
Diet, Mediterranean , Humans , Diet, Mediterranean/statistics & numerical data , Diet, Mediterranean/psychology , Greece , Cyprus , Male , Female , Adult , Middle Aged , Surveys and Questionnaires , Personal Satisfaction , Feeding Behavior/psychology , Socioeconomic Factors , Life Style , Quality of Life , Aged , Exercise/psychology , Young Adult
7.
Orphanet J Rare Dis ; 19(1): 167, 2024 Apr 18.
Article in English | MEDLINE | ID: mdl-38637882

ABSTRACT

The report covers the current and past activities of the department Molecular Genetics-Function and Therapy (MGFT) at the Cyprus Institute of Neurology and Genetics (CING), an affiliated Reference Center for the European Reference Network on Rare Endocrine Conditions (Endo-ERN).The presented data is the outcome of > 15 years long standing collaboration between MGFT and endocrine specialists from the local government hospitals and the private sector. Up-to-date > 2000 genetic tests have been performed for the diagnosis of inherited rare endocrine disorders. The major clinical entities included Congenital Adrenal Hyperplasia (CAH) due to pathogenic variants in CYP21A2 gene and Multiple Endocrine Neoplasia (MEN) type 2 due to pathogenic variants in the RET proto-oncogene. Other rare and novel pathogenic variants in ANOS1, WDR11, FGFR1, RNF216, and CHD7 genes were also found in patients with Congenital Hypogonadotropic Hypogonadism. Interestingly, a few patients with Disorders of Sexual Differentiation (DSD) shared rare pathogenic variants in the SRD5A2, HSD17B3 and HSD3B2 while patients with Glucose and Insulin Homeostasis carried theirs in GCK and HNF1A genes. Lastly, MGFT over the last few years has established an esteemed diagnostic and research program on premature puberty with emphasis on the implication of MKRN3 gene on the onset of the disease and the identification of other prognosis biomarkers.As an Endo-ERN member MGFT department belongs to this large European network and holds the same humanistic ideals which aim toward the improvements of health care for patients with rare endocrine conditions in respect to improved and faster diagnosis.


Subject(s)
Adrenal Hyperplasia, Congenital , Endocrine System Diseases , Multiple Endocrine Neoplasia Type 2a , Humans , Cyprus , Multiple Endocrine Neoplasia Type 2a/diagnosis , Multiple Endocrine Neoplasia Type 2a/genetics , Endocrine System Diseases/diagnosis , Endocrine System Diseases/genetics , Adrenal Hyperplasia, Congenital/diagnosis , Adrenal Hyperplasia, Congenital/genetics , Genetic Testing , Ubiquitin-Protein Ligases , Steroid 21-Hydroxylase/genetics , Membrane Proteins/genetics , 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
8.
Afr J Reprod Health ; 28(2): 107-115, 2024 Feb 28.
Article in English | MEDLINE | ID: mdl-38425233

ABSTRACT

This study was conducted as a pretest-posttest quasi-experimental design to determine the effect of planned education on the genital hygiene behaviors of secondary school female students in northern Cypurs. The research was conducted with 290 adolescents. Data were collected by using a personal information form and the Genital Hygiene Behavior Scale (GHBS). The paired sample t-test was used to analyze the data. It was determined that only 55.2 % of the adolescents received genital hygiene training, 11.7% had a genital infection and 48.6% used cosmetic products for the genital area. After education, there was a statistically significant increase in the GHBS scores and its dimensions, indicating the effectiveness and necessity of genital hygiene education. Genital hygiene education had a positive effect on the knowledge and practices of adolescent females. Therefore, planned education on genital hygiene, in which nurses play an important role, can be conducted regularly educations and home visits.


Cette étude a été menée sous la forme d'un plan quasi-expérimental prétest-posttest pour déterminer l'effet de l'éducation planifiée sur les comportements d'hygiène génitale des étudiantes du secondaire. La recherche a été menée auprès de 290 adolescents. Les données ont été collectées à l'aide d'un formulaire de renseignements personnels et de l'échelle de comportement en matière d'hygiène génitale (GHBS). Le test t pour échantillons appariés a été utilisé pour analyser les données. Il a été constaté que seulement 55,2 % des adolescents avaient reçu une formation en hygiène génitale, 11,7 % souffraient d'une infection génitale et 48,6 % utilisaient des produits cosmétiques pour la région génitale. Après l'éducation, il y a eu une augmentation statistiquement significative des scores GHBS et de ses dimensions, indiquant l'efficacité et la nécessité de l'éducation à l'hygiène génitale. L'éducation à l'hygiène génitale a eu un effet positif sur les connaissances et les pratiques des adolescentes. Par conséquent, une éducation planifiée sur l'hygiène génitale, dans laquelle les infirmières jouent un rôle important, peut être dispensée régulièrement et des visites à domicile.


Subject(s)
Health Knowledge, Attitudes, Practice , Hygiene , Humans , Adolescent , Female , Cyprus , Hygiene/education , Schools , Health Education
9.
Genes (Basel) ; 15(3)2024 Feb 28.
Article in English | MEDLINE | ID: mdl-38540378

ABSTRACT

Inherited cardiomyopathies represent a highly heterogeneous group of cardiac diseases. DNA variants in genes expressed in cardiomyocytes cause a diverse spectrum of cardiomyopathies, ultimately leading to heart failure, arrythmias, and sudden cardiac death. We applied massive parallel DNA sequencing using a 72-gene panel for studying inherited cardiomyopathies. We report on variants in 25 families, where pathogenicity was predicted by different computational approaches, databases, and an in-house filtering analysis. All variants were validated using Sanger sequencing. Familial segregation was tested when possible. We identified 41 different variants in 26 genes. Analytically, we identified fifteen variants previously reported in the Human Gene Mutation Database: twelve mentioned as disease-causing mutations (DM) and three as probable disease-causing mutations (DM?). Additionally, we identified 26 novel variants. We classified the forty-one variants as follows: twenty-eight (68.3%) as variants of uncertain significance, eight (19.5%) as likely pathogenic, and five (12.2%) as pathogenic. We genetically characterized families with a cardiac phenotype. The genetic heterogeneity and the multiplicity of candidate variants are making a definite molecular diagnosis challenging, especially when there is a suspicion of incomplete penetrance or digenic-oligogenic inheritance. This is the first systematic study of inherited cardiac conditions in Cyprus, enabling us to develop a genetic baseline and precision cardiology.


Subject(s)
Cardiomyopathies , Multifactorial Inheritance , Humans , Cyprus/epidemiology , Cardiomyopathies/genetics , Mutation , Sequence Analysis, DNA
10.
J Antimicrob Chemother ; 79(5): 933-934, 2024 May 02.
Article in English | MEDLINE | ID: mdl-38442334

ABSTRACT

Recent European-wide data place Cyprus and Greece in the highest positions of total antimicrobial consumption. While this level of consumption might be partly attributed to the high rates of infections due to MDR bacteria in these countries, several other reasons should be sought to help apply local measures, to decrease inappropriate and excess antimicrobial use. The present viewpoint aims to provide a roadmap for interventions, by briefly discussing the various factors that underlie antimicrobial use and prescribing practices in Greece and Cyprus.


Subject(s)
Anti-Bacterial Agents , Drug Utilization , Anti-Bacterial Agents/therapeutic use , Humans , Cyprus , Greece , Drug Utilization/statistics & numerical data , Bacterial Infections/drug therapy
11.
PLoS One ; 19(3): e0299765, 2024.
Article in English | MEDLINE | ID: mdl-38507432

ABSTRACT

Navigation in the Mediterranean in the Neolithic is studied here through the boats that were used, the degree of technical specialisation in their construction and, above all, their chronology. After a brief explanation of the exceptional site of La Marmotta, the characteristics and chronology of the five canoes found at the settlement and one of the nautical objects linked to Canoe 1 are discussed. This will allow a reflection on the capability of Neolithic societies for navigation owing to their high technological level. This technology was an essential part in the success of their expansion, bearing in mind that in a few millennia they occupied the whole Mediterranean from Cyprus to the Atlantic seaboard of the Iberian Peninsula.


Subject(s)
Ships , Italy , Cyprus
12.
J Cancer Educ ; 39(2): 211-212, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38356115

ABSTRACT

This paper explores a novel approach in cancer healthcare, underscoring the significance of fostering health literacy among doctors by enhancing their ability to employ linguistically oriented strategies to extract and interpret the linguistic behavior of patients. The focus is on the Greek-Cypriot context, where research on health literacy is still in its nascent stages.


Subject(s)
Health Literacy , Neoplasms , Physicians , Humans , Cyprus , Delivery of Health Care
13.
Eur J Public Health ; 34(2): 402-410, 2024 Apr 03.
Article in English | MEDLINE | ID: mdl-38326993

ABSTRACT

BACKGROUND: During the COVID-19 pandemic, the majority of patients received ambulatory treatment, highlighting the importance of primary health care (PHC). However, there is limited knowledge regarding PHC workload in Europe during this period. The utilization of COVID-19 PHC indicators could facilitate the efficient monitoring and coordination of the pandemic response. The objective of this study is to describe PHC indicators for disease surveillance and monitoring of COVID-19's impact in Europe. METHODS: Descriptive, cross-sectional study employing data obtained through a semi-structured ad hoc questionnaire, which was collectively agreed upon by all participants. The study encompasses PHC settings in 31 European countries from March 2020 to August 2021. Key-informants from each country answered the questionnaire. Main outcome: the identification of any indicator used to describe PHC COVID-19 activity. RESULTS: Out of the 31 countries surveyed, data on PHC information were obtained from 14. The principal indicators were: total number of cases within PHC (Belarus, Cyprus, Italy, Romania and Spain), number of follow-up cases (Croatia, Cyprus, Finland, Spain and Turkey), GP's COVID-19 tests referrals (Poland), proportion of COVID-19 cases among respiratory illnesses consultations (Norway and France), sick leaves issued by GPs (Romania and Spain) and examination and complementary tests (Cyprus). All COVID-19 cases were attended in PHC in Belarus and Italy. CONCLUSIONS: The COVID-19 pandemic exposes a crucial deficiency in preparedness for infectious diseases in European health systems highlighting the inconsistent recording of indicators within PHC organizations. PHC standardized indicators and public data accessibility are urgently needed, conforming the foundation for an effective European-level health services response framework against future pandemics.


Subject(s)
COVID-19 , Humans , COVID-19/epidemiology , Pandemics , Cross-Sectional Studies , Primary Health Care , Cost of Illness , Cyprus
14.
J Fish Biol ; 104(5): 1401-1410, 2024 May.
Article in English | MEDLINE | ID: mdl-38346402

ABSTRACT

Invasive species pose serious threats to ecosystems. To reduce ecological and economic consequences of invasions, efforts are made to control invaders and evaluating the effects of such efforts is paramount. Lionfishes (Pterois volitans and Pterois miles) are native to the Indo-Pacific Ocean and pose a major threat to local ecosystems in the invaded Atlantic and Mediterranean. Culling via spearfishing is a widespread measure to limit lionfish population size in invaded ranges. However, like most hunted fishes, lionfish alter their behavior after repeated culling, potentially decreasing the effectiveness of future culls. Previous studies on lionfish in the Caribbean have shown that lionfish are less bold after repeated culling. However, the impact of culling on lionfish in their newest invasive range, the Mediterranean, remains enigmatic. To determine the behavioral changes in response to culling in this second area of invasion, we tested for effects of culling on the behavior of lionfish in Cyprus, a region heavily impacted by the lionfish invasion in the Mediterranean. We compared the response of lionfish to an approaching free diver holding a metal pole (imitating a spear fisher) between protected areas where spearfishing is restricted and areas where culls are frequently conducted. We also assessed whether activity, hiding pattern, and site fidelity differed between these culled and unculled sites. Overall, we found limited effects of culling on the traits measured, indicating surprising resistance to culling-induced behavioral changes in Mediterranean lionfish. Future studies should monitor invasive lionfish population densities and the effects of culling in more detail to tailor management plans and reduce the negative effects of these fish in specific invaded ranges.


Subject(s)
Introduced Species , Perciformes , Animals , Perciformes/physiology , Mediterranean Sea , Behavior, Animal , Cyprus , Population Density , Conservation of Natural Resources
15.
Thorax ; 79(6): 495-507, 2024 May 20.
Article in English | MEDLINE | ID: mdl-38388489

ABSTRACT

INTRODUCTION: Elevated particulate matter (PM) concentrations of anthropogenic and/or desert dust origin are associated with increased morbidity among children with asthma. OBJECTIVE: The Mitigating the Health Effects of Desert Dust Storms Using Exposure-Reduction Approaches randomised controlled trial assessed the impact of exposure reduction recommendations, including indoor air filtration, on childhood asthma control during high desert dust storms (DDS) season in Cyprus and Greece. DESIGN, PARTICIPANTS, INTERVENTIONS AND SETTING: Primary school children with asthma were randomised into three parallel groups: (a) no intervention (controls); (b) outdoor intervention (early alerts notifications, recommendations to stay indoors and limit outdoor physical activity during DDS) and (c) combined intervention (same as (b) combined with indoor air purification with high efficiency particulate air filters in children's homes and school classrooms. Asthma symptom control was assessed using the childhood Asthma Control Test (c-ACT), spirometry (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC)) and fractional exhaled nitric oxide (FeNO). RESULTS: In total, 182 children with asthma (age; mean=9.5, SD=1.63) were evaluated during 2019 and 2021. After three follow-up months, the combined intervention group demonstrated a significant improvement in c-ACT in comparison to controls (ß=2.63, 95% CI 0.72 to 4.54, p=0.007), which was more profound among atopic children (ß=3.56, 95% CI 0.04 to 7.07, p=0.047). Similarly, FEV1% predicted (ß=4.26, 95% CI 0.54 to 7.99, p=0.025), the need for any asthma medication and unscheduled clinician visits, but not FVC% and FeNO, were significantly improved in the combined intervention compared with controls. CONCLUSION: Recommendations to reduce exposure and use of indoor air filtration in areas with high PM pollution may improve symptom control and lung function in children with asthma. TRIAL REGISTRATION NUMBER: NCT03503812.


Subject(s)
Asthma , Dust , Humans , Asthma/prevention & control , Child , Male , Female , Cyprus , Particulate Matter/analysis , Particulate Matter/adverse effects , Air Pollution/adverse effects , Air Pollution/analysis , Environmental Exposure/adverse effects , Environmental Exposure/prevention & control , Greece , Air Filters , Air Pollution, Indoor/adverse effects , Air Pollution, Indoor/prevention & control , Nitric Oxide/analysis , Air Pollutants/analysis , Air Pollutants/adverse effects , Forced Expiratory Volume
16.
Comput Biol Med ; 171: 108094, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38335823

ABSTRACT

Pseudomonas aeruginosa, a resilient gram-negative bacterium, poses a persistent threat as a leading cause of nosocomial infections, particularly in resource-constrained regions. Despite existing treatment and control measures, the bacterium continues to challenge healthcare systems, especially in developing nations. This paper introduces a fractional-order model to elucidate the dynamic behavior of nosocomial infections caused by P. aeruginosa and to compare the efficacy of carbapenems and aminoglycosides in treatment. The model's existence and uniqueness are established, and both global and local stability are confirmed. The effective reproduction number is computed, revealing an epidemic potential with a value of 1.02 in Northern Cyprus. Utilizing real-life data from a university hospital and employing numerical simulations, our results indicate that patients exhibit higher sensitivity and lower resistance to aminoglycoside treatment compared to carbapenems. Aminoglycosides consistently outperform carbapenems across key metrics, including the reduction of susceptible population, infection numbers, treatment efficacy, total infected population, hospital occupancy, and effective reproduction number. The fractional-order approach emerges as a suitable and insightful tool for studying the transmission dynamics of the disease and assessing treatment effectiveness. This research provides a robust foundation for refining treatment strategies against P. aeruginosa infections, contributing valuable insights for healthcare practitioners and policymakers alike.


Subject(s)
Cross Infection , Pseudomonas Infections , Humans , Pseudomonas aeruginosa , Cross Infection/drug therapy , Cross Infection/epidemiology , Cross Infection/microbiology , Cyprus , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Pseudomonas Infections/drug therapy , Pseudomonas Infections/epidemiology , Pseudomonas Infections/microbiology , Carbapenems/pharmacology , Carbapenems/therapeutic use , Aminoglycosides , Microbial Sensitivity Tests
17.
Sci Total Environ ; 922: 171247, 2024 Apr 20.
Article in English | MEDLINE | ID: mdl-38423333

ABSTRACT

Irrigation is considered a form of agricultural intensification and is of significant importance in arid and semi-arid regions, such as those in the Mediterranean basin. This region differs substantially from temperate ones, in terms of climate, land-use policies and types of agricultural systems. Therefore, how biodiversity is affected by agricultural intensification may also differ substantially from countries in north-western Europe. We investigated the effect of irrigation on butterfly diversity and abundance at two different spatial scales in an agricultural region in northern Cyprus, an area representative of typical lowland agricultural practices of the Eastern Mediterranean. We investigated how local field-scale management (irrigated vs rain-fed) and the proportion of irrigated land at a larger scale of 0.25 km2 affected the abundance and diversity of butterflies and herbaceous plant species. Butterflies and herbaceous plants were surveyed in field boundaries adjacent to agricultural fields located in paired plots that had contrasting levels of irrigation. Butterflies in the field boundaries along agricultural fields were strongly positively affected by irrigation in the adjacent fields both in terms of abundance and species diversity, whereas the effect of irrigation at the larger scale of the 0.25-km2 plot was less prominent. Species composition of butterflies and plants did not correlate. However, plant abundance and alpha diversity of the vegetation in the field boundaries correlated with both abundance and alpha diversity of the butterflies when the abundance of plants was relatively low, in particular, when grasses were omitted from the data set. Crop species associated with irrigated fields contributed to the observed patterns. Comparing the results of this study with those reported for temperate regions in northwestern Europe reveals that the effectiveness of management schemes on biodiversity depend on biogeographical region, highlighting the risk of making broad assumption on the effectiveness of management strategies on biodiversity.


Subject(s)
Butterflies , Animals , Farms , Biodiversity , Agriculture , Plants , Cyprus , Ecosystem
18.
PLoS One ; 19(2): e0292790, 2024.
Article in English | MEDLINE | ID: mdl-38315645

ABSTRACT

Cyprus was conquered from several populations because of its special geographical location. In this study, 406 unrelated Cypriot samples were tested based on their mitochondrial DNA. In more detail, 185 were Greek Cypriots, 114 Armenian Cypriots and 107 Maronite Cypriots. This is the first time where the mitochondrial DNA of Greek Cypriots, Armenian Cypriots and Maronite Cypriots is compared with the aim of characterizing the maternal ancestry of Cypriots. The control region of the mtDNA is the most informative in terms of studying maternal ancestry and consists of three hypervariable regions (HVS-I, HVS-II, HVS-III). The hypervariable regions can provide important information regarding the maternal ancestor of the tested samples. The entire control region of the mtDNA was used to determine the mitotypes and subsequently the haplogroups of all the Cypriot DNA samples. Based on the aforementioned analyses, Greek Cypriots were found to be genetically closer to Armenian Cypriots, while Greek Cypriots and Armenian Cypriots showed moderate genetic differentiation with Maronite Cypriots. The most prevalent haplogroups among Cypriots were haplogroups H and U, while R0 is common but in different frequencies for Greek Cypriots, Armenian Cypriots and Maronite Cypriots. It is proposed that the maternal ancestor may have originated during the Neolithic period and/or the Bronze age.


Subject(s)
DNA, Mitochondrial , Humans , Greece , Armenia , DNA, Mitochondrial/genetics , Cyprus , Haplotypes
19.
Niger J Clin Pract ; 27(2): 188-193, 2024 Feb 01.
Article in English | MEDLINE | ID: mdl-38409146

ABSTRACT

BACKGROUND: Congenital diseases are still an important medical, social, and economic problem all over the world. In North Cyprus, in addition to other reasons, early prenatal diagnostic measures are undertaken to prevent births with thalassemia major, a locally widespread genetic disease. AIM: This study aims to evaluate the results of prenatal invasive diagnostic tests performed in a private obstetrics clinic in Northern Cyprus and show the diagnosis process of thalassemia and chromosomal anomalies. MATERIALS AND METHODS: This study is a retrospective, descriptive study. Chorionic villus sampling (CVS) results and the amniocentesis tests performed between 1990 and 2022 are evaluated. Thalassemia and chromosome analysis of samples obtained by CVS and amniocentesis tests were performed. To diagnose alpha or beta thalassemia and sickle cell, 239 CVS was performed. And to diagnose chromosomal anomalies, 396 CVS and amniocentesis were performed. RESULTS: The mean age of the 480 pregnant women included in the study was 31.12 years (18-46) and 30% of them were older than 34 years. The most common indications for invasive prenatal diagnostic test (IPDT) were; mother/father thalassemia minor/major, advanced maternal age, high risk of ultrasonography erase findings, and the noninvasive screening test. The result of IPDT detected 7.3% chromosomal anomaly and 69.5% thalassemia and sickle cell anemia. Of the 239 CVS performed to diagnose alpha or beta thalasemia and sickle cell, 23.4% beta major, 42.3% beta minor, and 2.1% alpha minor were diagnosed. Of the 396 CVS and amniocentesis performed to diagnose chromosomal anormalies; 2.8% of Down syndrome and 4.54% of other chromosomal anomalies were diagnosed. CONCLUSION: IPDT is important in correctly diagnosing fetal anomalies at the prenatal stage to help families decide at the right time.


Subject(s)
Anemia, Sickle Cell , Chromosome Disorders , Thalassemia , Pregnancy , Female , Humans , Adolescent , Young Adult , Adult , Middle Aged , Retrospective Studies , Cyprus , Prenatal Diagnosis/methods , Chorionic Villi Sampling , Chromosome Aberrations , Diagnostic Tests, Routine
20.
Int J Older People Nurs ; 19(1): e12593, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38268314

ABSTRACT

BACKGROUND: Social activities decelerate the deterioration of mental capacity in older people and improve their physical and psychosocial health. Valid and reliable measurement tools are needed to determine the social activity status of older people and plan health services to protect their mental health. OBJECTIVE: This study aimed to adapt the Social Activities Scale for Community-Dwelling Older People Requiring Support (SASOS) into Turkish. METHODS: This methodological study was conducted in Northern Cyprus between January and June 2022. Convenience sampling was used to recruit 155 community-dwelling older people who needed support. Expert opinion, item-content validity index, and scale-content validity index were used to evaluate content validity. Internal consistency and test-retest reliability tests were used to evaluate reliability. Exploratory factor analysis was used to evaluate construct validity. The Loneliness Scale for Elderly was used to evaluate concurrent validity. RESULTS: The Cronbach's alpha of SASOS was 0.90. Additionally, correlation coefficients of all items ranged between 0.61 and 0.79. Exploratory factor analysis revealed a three-factor structure. 'Interactions with friends and neighbors' was the factor that explained the highest variance (46%). There was a negative, weak, and statistically significant relationship between the scores obtained from the social loneliness subscale of LSE and all three subscales of SASOS. CONCLUSIONS: The Turkish version of SASOS is a valid, reliable instrument to evaluate social activities in community-dwelling older people who needed support. IMPLICATIONS FOR PRACTICE: The SASOS has been identified as a valuable measure for assessing the social support needs of older individuals. It serves as a guide for both planning and evaluating interventions to enhance their health.


Subject(s)
Independent Living , Aged , Humans , Psychometrics , Reproducibility of Results , Cyprus , Factor Analysis, Statistical
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