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1.
Adv Skin Wound Care ; 36(7): 1-4, 2023 Jul 01.
Article in English | MEDLINE | ID: mdl-37338952

ABSTRACT

ABSTRACT: Eccrine angiomatous hamartoma (EAH) is a rare hamartoma characterized by a benign proliferation of eccrine glands and vascular structures in the dermis. These tumors rarely regress spontaneously, so surgical excision of the involved tissue is required when pain or enlargement occurs. Here, the authors report the clinical case of a patient affected by an extremely painful EAH with the atypical localization at the last phalanx of the thumb of the right hand with involvement of nail matrix and nail bed. This report aims to emphasize the application of Mohs micrographic surgery for the treatment of painful EAH in a very difficult area at potential risk of amputation while preserving the maximum anatomical integrity and function of the damaged area. These results can pave the way for the use of Mohs micrographic surgery for very carefully selected benign neoplasms when their surgical removal is required.


Subject(s)
Hamartoma , Sweat Gland Diseases , Humans , Mohs Surgery , Sweat Gland Diseases/diagnosis , Sweat Gland Diseases/surgery , Sweat Gland Diseases/pathology , Eccrine Glands/pathology , Eccrine Glands/surgery , Hamartoma/complications , Hamartoma/surgery , Hamartoma/pathology , Hand , Pain
3.
Medicine (Baltimore) ; 100(20): e25971, 2021 May 21.
Article in English | MEDLINE | ID: mdl-34011082

ABSTRACT

RATIONALE: Eccrine poroma, a benign cutaneous neoplasm originating from the intraepidermal portion of the eccrine sweat duct, is relatively common in clinical practice. Nevertheless, the 1 presenting as spindle-shaped plaque is extremely rare and easily misdiagnosed as seborrheic keratosis or other dermatoses. Thus, the current study demonstrates a case of eccrine poroma with unique clinical manifestation. PATIENTS CONCERNS: A 47-year-old man presented with a spindle-shaped plaque on his left sole for 6 years. DIAGNOSES: Based on the clinical and histopathological manifestations, diagnosis of eccrine poroma was established. INTERVENTIONS: Surgical excision under local anesthesia was performed. OUTCOMES: No recurrence or malignant transformation occurred within 6-month follow-up. LESSONS: Eccrine poroma typically presents as a dome-shaped nodule on palm or sole. But this case reminded us the lesion presenting as a spindle-shaped plaque on sole can not rule out the possibility of eccrine poroma.


Subject(s)
Eccrine Glands/pathology , Poroma/diagnosis , Sweat Gland Neoplasms/diagnosis , Eccrine Glands/surgery , Foot , Humans , Male , Middle Aged , Poroma/pathology , Poroma/surgery , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/surgery , Treatment Outcome
5.
Am J Case Rep ; 20: 1896-1901, 2019 Dec 19.
Article in English | MEDLINE | ID: mdl-31852881

ABSTRACT

BACKGROUND Syringoid eccrine carcinoma (SEC) is an extremely rare malignant adnexal neoplasm derived from eccrine sweat glands, of unknown pathogenesis. We report a case of this rare entity presenting in the abdomen, which is the only one reported in this area and the only case of SEC in a patient with so many comorbidities. CASE REPORT A 58-year-old black male from Brazil reported a nodular lesion in the abdomen with a progressive increase in size and pain and local burning sensation. The histopathological examination showed a syringoid eccrine carcinoma. CONCLUSIONS We present a rare case of SEC and did an extensive literature review in order to describe the clinical characteristics, histopathological findings, immunohistochemical profile, treatments, and difficulties found in the diagnosis of this tumor. To avoid misdiagnosis, we gave special attention to biopsy quality.


Subject(s)
Abdominal Wall/pathology , Abdominal Wall/surgery , Carcinoma/surgery , Eccrine Glands/pathology , Eccrine Glands/surgery , Sweat Gland Neoplasms/surgery , Syringoma/surgery , Humans , Male , Middle Aged , Rare Diseases
6.
An. bras. dermatol ; 93(6): 893-895, Nov.-Dec. 2018. graf
Article in English | LILACS | ID: biblio-973624

ABSTRACT

Abstract: Squamoid eccrine ductal carcinoma is a cutaneous malignancy that originates from the eccrine sweat gland. A 76-year-old woman presented with an asymptomatic papule on her nose that had been present for one year. Dermoscopy showed pseudocysts, irregular linear crown vessels, and yellowish-brown globules surrounded by white halos. This is the first dermoscopic description of squamoid eccrine ductal carcinoma. Studies with more cases are needed to confirm the dermoscopic characterization of this tumor.


Subject(s)
Humans , Female , Aged , Skin Neoplasms/pathology , Carcinoma, Squamous Cell/diagnosis , Eccrine Glands/pathology , Skin Neoplasms/surgery , Skin Neoplasms/diagnosis , Immunohistochemistry , Carcinoma, Squamous Cell/surgery , Carcinoma, Squamous Cell/pathology , Early Diagnosis , Dermoscopy , Diagnosis, Differential , Eccrine Glands/surgery
7.
An Bras Dermatol ; 93(6): 893-895, 2018.
Article in English | MEDLINE | ID: mdl-30484539

ABSTRACT

Squamoid eccrine ductal carcinoma is a cutaneous malignancy that originates from the eccrine sweat gland. A 76-year-old woman presented with an asymptomatic papule on her nose that had been present for one year. Dermoscopy showed pseudocysts, irregular linear crown vessels, and yellowish-brown globules surrounded by white halos. This is the first dermoscopic description of squamoid eccrine ductal carcinoma. Studies with more cases are needed to confirm the dermoscopic characterization of this tumor.


Subject(s)
Carcinoma, Squamous Cell/diagnosis , Eccrine Glands/pathology , Skin Neoplasms/pathology , Aged , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/surgery , Dermoscopy , Diagnosis, Differential , Early Diagnosis , Eccrine Glands/surgery , Female , Humans , Immunohistochemistry , Skin Neoplasms/diagnosis , Skin Neoplasms/surgery
8.
Exp Dermatol ; 27(6): 678-681, 2018 06.
Article in English | MEDLINE | ID: mdl-29392864

ABSTRACT

We describe a simple and efficient method to isolate eccrine sweat glands from the human scalp. This method is inspired by the hair graft harvesting method used in hair transplantation. Based on the recently described anatomical relationship between the scalp hair follicle and the eccrine gland, we have found that scalp follicular unit grafts are an excellent eccrine gland isolation source, especially for the coiled component. In order to make the gland visible for stereoscopic microdissection, the follicular units need to be previously stained with a vital dye like methylene blue or neutral red. The simplicity and efficiency of this isolation method should encourage further research into human eccrine sweat gland function which has always been hindered by the difficulty of gland isolation.


Subject(s)
Coloring Agents , Eccrine Glands/surgery , Scalp , Staining and Labeling/methods , Eccrine Glands/anatomy & histology , Hair Follicle/anatomy & histology , Humans , Methylene Blue , Microdissection , Neutral Red , Scalp/anatomy & histology , Tissue and Organ Harvesting/methods
11.
Indian J Cancer ; 54(4): 695-696, 2017.
Article in English | MEDLINE | ID: mdl-30082561

ABSTRACT

Eccrine spiradenoma is one of the rare adnexal tumors with eccrine differentiation; however, it is considered to have apocrine differentiation. Around 50 cases of eccrine spiradenoma have been reported in the literature. Due to vascularity and painful symptoms, it is often confused with the painful lesions of skin such as glomus tumor and angioleiomyoma. Surgical excision is considered the gold standard for the treatment of these cases, with low rates of recurrence. Here, we present a 52-year-old male who presented with a nodular lesion in the left side of chest for the past 4 years. Surgical excision was performed and the tissue was sent for histopathological examination. Eccrine Spiradenoma may present congenitally or spontaneously as tumor of the sweat glands with unclear etiology. Early accurate diagnosis is very important in preventing chances of recurrence and more importantly identifying onset of malignant transformation.


Subject(s)
Acrospiroma/diagnosis , Adenoma/diagnosis , Eccrine Glands/surgery , Sweat Gland Neoplasms/diagnosis , Acrospiroma/pathology , Acrospiroma/surgery , Adenoma/pathology , Adenoma/surgery , Eccrine Glands/pathology , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/pathology , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/surgery
16.
An Bras Dermatol ; 90(3 Suppl 1): 235-8, 2015.
Article in English | MEDLINE | ID: mdl-26312727

ABSTRACT

Eccrine syringofibroadenoma is a rare benign adnexal neoplasm derived from cells of the acrosyringium of eccrine sweat glands. ESFA usually manifests as a solitary nodule on the extremities of elderly patients, but it may also present as papules, nodules or plaques. Its clinical appearance is nonspecific and malignant neoplasms should be considered in the differential diagnosis. However, histopathological findings are typical. The main treatment is surgical excision. In order to illustrate a typical presentation of the tumor, we report a case of solitary eccrine syringofibroadenoma, including the surgical treatment used and its result.


Subject(s)
Eccrine Glands/pathology , Fibroadenoma/pathology , Sweat Gland Neoplasms/pathology , Syringoma/pathology , Aged, 80 and over , Ankle , Biopsy , Eccrine Glands/surgery , Female , Fibroadenoma/surgery , Humans , Sweat Gland Neoplasms/surgery , Syringoma/surgery , Treatment Outcome
17.
An. bras. dermatol ; 90(3,supl.1): 235-238, May-June 2015. ilus
Article in English | LILACS | ID: lil-755753

ABSTRACT

Abstract

Eccrine syringofibroadenoma is a rare benign adnexal neoplasm derived from cells of the acrosyringium of eccrine sweat glands. ESFA usually manifests as a solitary nodule on the extremities of elderly patients, but it may also present as papules, nodules or plaques. Its clinical appearance is nonspecific and malignant neoplasms should beconsidered in the differential diagnosis. However, histopathological findings are typical. The main treatment is surgical excision. In order to illustrate a typical presentation of the tumor, we report a case of solitary eccrine syringofibroadenoma, including the surgical treatment used and its result.

.


Subject(s)
Aged, 80 and over , Female , Humans , Eccrine Glands/pathology , Fibroadenoma/pathology , Sweat Gland Neoplasms/pathology , Syringoma/pathology , Ankle , Biopsy , Eccrine Glands/surgery , Fibroadenoma/surgery , Sweat Gland Neoplasms/surgery , Syringoma/surgery , Treatment Outcome
18.
Am J Dermatopathol ; 37(2): 167-70, 2015 Feb.
Article in English | MEDLINE | ID: mdl-24335519

ABSTRACT

Eccrine nevus shows increase in number or size of eccrine glands, whereas hair follicle nevus is composed of densely packed normal vellus hairs, and eccrine-pilar angiomatous nevus reveals increase of eccrine, pilar, and angiomatous structures. No case with increased number of both eccrine glands and hair follicles only in the dermis has been previously reported. A 10-month-old girl presented with cutaneous hamartoma with overlying skin hyperpigmentation on her left hypochondrium since 3 months of age, in whom the lesion was completely excised. Histopathology demonstrated evidently increased number of both eccrine glands and hair follicles in the dermis with reactive hyperplasia of collagen fibers. No recurrence occurred after the tumor was completely excised. A term "hybrid eccrine gland and hair follicle hamartoma" is proposed for this unique lesion.


Subject(s)
Eccrine Glands/pathology , Hair Follicle/pathology , Hamartoma/pathology , Neoplasms, Adnexal and Skin Appendage/pathology , Nevus/pathology , Skin Neoplasms/pathology , Biopsy , Eccrine Glands/surgery , Female , Hair Follicle/surgery , Hamartoma/classification , Hamartoma/surgery , Humans , Infant , Neoplasms, Adnexal and Skin Appendage/classification , Neoplasms, Adnexal and Skin Appendage/surgery , Nevus/classification , Nevus/surgery , Predictive Value of Tests , Skin Neoplasms/classification , Skin Neoplasms/surgery , Terminology as Topic
19.
Am J Dermatopathol ; 36(8): 679-82, 2014 Aug.
Article in English | MEDLINE | ID: mdl-25051045

ABSTRACT

Cutaneous ciliated cysts (CCC) are rare benign cysts known to occur in the lower extremities of females of reproductive age. Currently, there are 2 theories that attempt to explain the histogenesis of this rare entity. The theory of Mullerian heterotopia provides a plausible histogenetic explanation for the vast majority of CCC. A proposed alternative theory is the ciliated metaplasia of eccrine glands. We believe that previously reported cases of CCC include 2 distinct entities. We report, herein, the first case reported in the literature of a cutaneous ciliated eccrine cyst occurring on the scalp.


Subject(s)
Cysts/pathology , Eccrine Glands/pathology , Scalp/pathology , Biomarkers/analysis , Biopsy , Cysts/chemistry , Cysts/surgery , Eccrine Glands/chemistry , Eccrine Glands/surgery , Female , Humans , Immunohistochemistry , Metaplasia , Middle Aged , Scalp/chemistry , Scalp/surgery
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