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1.
Turkiye Parazitol Derg ; 44(4): 264-266, 2020 Dec 02.
Article in English | MEDLINE | ID: mdl-33269575

ABSTRACT

Scabies is a cutaneous infectious disease caused by the ectoparasite Sarcoptes scabiei. The disease has gained attention due to its increasing incidence in recent years. Rare and atypical forms of scabies can imitate many other cutaneous conditions. Such unfamiliar presentations may lead to misdiagnosis and mistreatment. Localised scabies is extremely rare and only few cases have been reported in the relevant literature. Herein, we report the case of a 4-month-old girl presenting with localised scabies limited to the right plantar surface. To the best of our knowledge, scabies restricted to the plantar region has never been reported in the paediatric population. Furthermore, scabies restricted to a single foot has never been reported in any age group. Awareness about the atypical and extraordinary manifestations of scabies can lead to early diagnosis and treatment and, thus, decrease disease-related morbidity and risk of transmission.


Subject(s)
Eczema/diagnosis , Exanthema/diagnosis , Scabies/diagnosis , Animals , Diagnosis, Differential , Eczema/parasitology , Eczema/pathology , Exanthema/parasitology , Exanthema/pathology , Female , Foot Dermatoses/diagnosis , Foot Dermatoses/parasitology , Foot Dermatoses/pathology , Humans , Infant , Sarcoptes scabiei/physiology , Scabies/parasitology , Scabies/pathology
3.
Am J Respir Crit Care Med ; 183(2): 165-70, 2011 Jan 15.
Article in English | MEDLINE | ID: mdl-20935107

ABSTRACT

RATIONALE: Acetaminophen has been hypothesized to increase the risk of asthma and allergic disease, and geohelminth infection to reduce the risk, but evidence from longitudinal cohort studies is lacking. OBJECTIVES: To investigate the independent effects of these exposures on the incidence of wheeze and eczema in a birth cohort. METHODS: In 2005-2006 a population-based cohort of 1,065 pregnant women from Butajira, Ethiopia, was established, to whom 1,006 live singleton babies were born. At ages 1 and 3, questionnaire data were collected on wheeze, eczema, child's use of acetaminophen, and various potential confounders, along with a stool sample for geohelminth analysis. Those without wheeze (n = 756) or eczema (n = 780) at age 1 were analyzed to determine the independent effects of geohelminth infection and acetaminophen use in the first year of life on the incidence of wheeze and eczema by age 3. MEASUREMENTS AND MAIN RESULTS: Wheeze and eczema incidence between the ages of 1 and 3 were reported in 7.7% (58 of 756) and 7.3% (57 of 780) of children, respectively. Acetaminophen use was significantly associated with a dose-dependent increased risk of incident wheeze (adjusted odds ratio = 1.88 and 95% confidence interval 1.03-3.44 for one to three tablets and 7.25 and 2.02-25.95 for ≥ 4 tablets in the past month at age 1 vs. never), but not eczema. Geohelminth infection was insufficiently prevalent (<4%) to compute estimates of effect. CONCLUSIONS: These findings suggest frequent acetaminophen use early in life increases the risk of new-onset wheeze, whereas the role of geohelminth infection on allergic disease incidence remains to be seen as the cohort matures.


Subject(s)
Acetaminophen/adverse effects , Drug Hypersensitivity/epidemiology , Eczema/chemically induced , Eczema/epidemiology , Helminthiasis/epidemiology , Respiratory Sounds/etiology , Analgesics, Non-Narcotic/adverse effects , Causality , Child, Preschool , Cohort Studies , Comorbidity , Dose-Response Relationship, Drug , Eczema/parasitology , Ethiopia/epidemiology , Feces/parasitology , Female , Follow-Up Studies , Helminthiasis/parasitology , Humans , Incidence , Infant , Longitudinal Studies , Male , Odds Ratio , Risk Factors , Surveys and Questionnaires
4.
J Am Acad Dermatol ; 59(6): 1031-42, 2008 Dec.
Article in English | MEDLINE | ID: mdl-18793816

ABSTRACT

Human toxocariasis is a parasitic disease characterized by the presence of larvae of the genus Toxocara in human tissues. T canis and T cati, the adult roundworms of which are found in dog and cat intestines, respectively, are the most common causative agents of the disease. Toxocaral larvae usually cause two severe syndromes: visceral larva migrans and ocular larva migrans, depending on the location of the larvae. Two other syndromes, covert toxocariasis and common toxocariasis, which are less typical and not as severe, have also been described. During the last two decades, cutaneous manifestations such as chronic urticaria, chronic pruritus, and miscellaneous eczema, in patients with Toxocara antibodies, have been studied by different authors. In some cases, these cutaneous manifestations are the only signs indicating the presence of the disease, and they are cured after antihelmintic treatment when there is good patient compliance. In this review, we focus on these particular skin manifestations regarding their clinical description, diagnosis, and treatment.


Subject(s)
Skin Diseases, Parasitic/diagnosis , Toxocariasis/pathology , Adult , Animals , Child , Child, Preschool , Dogs , Eczema/diagnosis , Eczema/parasitology , Humans , Pruritus/diagnosis , Pruritus/parasitology , Toxocara/immunology , Toxocariasis/diagnosis , Toxocariasis/immunology , Urticaria/diagnosis , Urticaria/parasitology
6.
Acta bioquím. clín. latinoam ; 36(2): 263-267, jun. 2002. ilus, tab
Article in Spanish | BINACIS | ID: bin-7894

ABSTRACT

Con el objeto de evaluar la importancia que tiene el hallazgo de Demodex sp. en dermatología humana, se realizó el presente estudio de casos y controles, completando con análisis químico del parásito. Los casos presentaban rosácea o eccematide seborreica, mientras que los controles, piel normal. Las muestras fueron extraídas del rostro mediante aplicación de cintas adhesivas transparentes sobre la piel, las que luego se adhirieron a portaobjetos para buscar el artrópodo por microscopía. El hallazgo de un solo parásito fue suficiente como criterio de positividad. Además se realizó análisis espectrofotométrico de los parásitos, por fluorescencia de rayos X. El 36,6 por ciento de los casos presentó Demodex sp. asociado con dermatitis perioral, rosácea, eccematide seborreica y en conducto nasal asociado a Staphylococcus aureus. Solamente en el 3,3 por ciento de los controles se demostró la presencia del parásito. Odds Ratio: 16,79; X²:8,44; p: 0,0036, límite de confianza 95 por ciento. El análisis espectrométrico por fluorescencia de rayos X, demostró presencia de: calcio, titanio, hierro, azufre, fósforo, cobre, níquel, zinc, potasio, cloro, magnesio, aluminio y silicio en los artrópodos, correspondiendo al cobre y al hierro los picos de mayor intensidad. Luego del tratamiento para Demodex sp. se produjo remisión de los cuadros. Se concluye que existe asociación estadísticamente significativa entre las dermatopatías mencionadas y Demodex sp. El cobre y el hierro de los parásitos podrían, eventualmente, contribuir a agravar los cuadros por reacciones alérgicas (AU)


Subject(s)
Humans , Male , Adult , Female , Middle Aged , Mite Infestations/etiology , Mites/pathogenicity , Opportunistic Infections , Skin/parasitology , Mite Infestations/drug therapy , Mites/drug effects , Skin Diseases, Parasitic/etiology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Dermatitis, Perioral/complications , Dermatitis, Perioral/parasitology , Rosacea/complications , Rosacea/parasitology , Skin Diseases, Eczematous/complications , Skin Diseases, Eczematous/parasitology , Eczema/complications , Eczema/parasitology , Stress, Psychological/complications , Pyrethrins/therapeutic use , Dermatitis, Perioral , Virus Diseases/complications , Permethrin/therapeutic use
7.
Bol. méd. Hosp. Infant. Méx ; 55(2): 83-8, feb. 1998. tab, ilus
Article in Spanish | LILACS | ID: lil-232672

ABSTRACT

Introducción. La dermatitis microbiana numular (DMN) se ha reportado en México con una frecuencia de 0.5 a 6 por ciento de la consulta dermatológica. Se realizó este estudio con el objeto de conocer el comportamiento de la DMN en nuestra población. Material y métodos. Se estudiaron retrospectivamente 33 casos, de enero de 1996 a enero de 1997, en el Hospital Infantil de México Federico Gómez. Resultados. La DMN representa el 2.78 por ciento de la consulta de dermatología de primera vez. Predomina en hombres con 63 por ciento de los casos. La edad media fue de 4 años y 10.8 meses con una desviación estándar (DE) de 7.4 meses. La forma diseminada fue la más común, afectando con mayor frecuencia extremidades inferiores. El tiempo de evolución el diagnóstico fue de 8.8 meses con DE de 2.3 meses. Se evidenció foco infeccioso en 79 por ciento de los casos, siendo rinosinusitis y parasitosis los más comunes. La biometría hemática reportó eosinofilia en más de la mitad de los pacientes. Sólo se encontró asociación a dermatitis atópica y atopia en 5 casos. La primavera fue la estación con mayor prevalencia. El tratamiento fue con antibióticos y antiparasitarios sistémicos en 27 pacientes y antihistamínicos en 9. Sólo un paciente requirió esteroide tópico. Más del 70 por ciento evolucionaron satisfactoriamente. Conclusiones. Los hallazgos de este estudio son similares a los referidos en la literatura mundial respecto a epidemiología, cuadro clínico y asociación con enfermedades infecciosas


Subject(s)
Humans , Male , Female , Child, Preschool , Adolescent , Anti-Bacterial Agents/therapeutic use , Eczema/classification , Eczema/epidemiology , Eczema/etiology , Eczema/microbiology , Eczema/parasitology , Histamine H1 Antagonists/therapeutic use , Leg/physiopathology , Skin Diseases, Infectious/classification , Skin Diseases, Infectious/epidemiology , Skin Diseases, Infectious/etiology
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