ABSTRACT
Se presenta la experiencia del consultorio de Patología Vulvar del Hospital Clínico de la Universidad de Chile, sobre liquen escleroso de la vulva, la que abarca desde 1976 a 1987. Durante este lapso se diagnosticaron 34 casos nuevos de esta enfermedad, evaluándose los resultados del tratamiento con propionato de testosterona y fluocortolona a lo largo de un seguimiento promedio de 3,2 años. Once de las treinta y cuatro pacientes, se controlaron por medio de biopsias vulvares. Comprobándose en dos casos mejoría histológica de las lesiones. No se observó tendencia a la malignización en ninguna de las pacientes estudiadas
Subject(s)
Child , Adolescent , Adult , Middle Aged , Humans , Female , Lichen Planus/drug therapy , Vulvar Diseases/drug therapy , Biopsy , Chronic Disease , Fluocortolone/therapeutic use , Testosterone/therapeutic use , Vulva/pathologySubject(s)
Adrenal Cortex Hormones/therapeutic use , Chlorquinaldol/therapeutic use , Dermatitis/drug therapy , Fluocortolone/therapeutic use , Pregnadienediols/therapeutic use , Clinical Trials as Topic , Double-Blind Method , Drug Combinations , Drug Evaluation , Fluocortolone/analogs & derivatives , Humans , Ointments , PlacebosABSTRACT
The object of the present study was to investigate the clinical efficacy of Nerisona fatty ointment in very skin conditions. A total of 37 patients, most of them with chronic dermatoses, was treated. Either very good or good results were achieved in 100% of the cases. The side effects observed were very slight.
Subject(s)
Fluocortolone/administration & dosage , Pregnadienediols/administration & dosage , Skin Diseases/drug therapy , Adolescent , Adult , Child , Child, Preschool , Chronic Disease , Clinical Trials as Topic , Drug Evaluation , Fluocortolone/adverse effects , Fluocortolone/analogs & derivatives , Fluocortolone/therapeutic use , Humans , Infant , Middle Aged , OintmentsABSTRACT
Nerisone cream (diflucortolon valerate 0.1%) has been clinically compared with fluocinolon-acetate on a double blind basis. The trial was carried out on 30 patients. The author comments that the results, in spite of some slight casuisties, appear to indicate a certain superiority of Nerisone cream when compared with the competitor's preparation.