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1.
J Clin Periodontol ; 49(6): 591-598, 2022 06.
Article in English | MEDLINE | ID: mdl-35262196

ABSTRACT

AIM: To investigate whether the periodontal condition as measured by bleeding periodontal pockets is associated with atopic dermatitis, seborrheic dermatitis, and eczema nummulare. MATERIALS AND METHODS: The study population (n = 1871) was obtained from the 46-year follow-up study of the Northern Finland Birth Cohort 1966 study (NFBC1966). The periodontal condition was measured by the number of sites with bleeding periodontal pockets that were ≥4 mm deep. The whole skin of the participants was clinically examined, and diagnoses of skin diseases were made according to the International Classification of Diseases. Prevalence rate ratios (PRR) and 95% confidence intervals (95% CIs) were estimated using Poisson regression models with robust error variance. RESULTS: In this cohort, comprising 46-year-old participants of NFBC1966, the presence of 1-3 and ≥4 bleeding-deepened periodontal pockets (≥4 mm deep) were associated with seborrheic dermatitis (PRR 1.9, 95% CI: 1.3-2.8 and PRR 2.2, 95% CI: 1.4-3.3, respectively) and with eczema nummulare (PRR 1.7, 95% CI: 0.9-3.1 and PRR 1.7, 95% CI: 0.9-3.3, respectively). For non-smokers, the corresponding estimates were 1.7 for seborrheic dermatitis (95% CI: 1.1-2.6) and 1.8 (95% CI: 1.1-3.1) and 1.4 for eczema nummulare (95% CI: 0.7-2.9) and 1.2 (95% CI: 0.5-2.9), respectively. No association was found between bleeding-deepened periodontal pockets and atopic dermatitis. Further adjustments for C-reactive protein, diabetes, and inflammatory diseases did not essentially change the risk estimates among either the total population or the non-smokers. CONCLUSION: Bleeding periodontal pockets appeared to be associated with the presence of seborrheic dermatitis and eczema nummulare.


Subject(s)
Dermatitis, Seborrheic , Eczema , Gingival Diseases , Periodontal Diseases , Birth Cohort , Dermatitis, Seborrheic/complications , Eczema/complications , Eczema/epidemiology , Finland/epidemiology , Follow-Up Studies , Gingival Diseases/complications , Humans , Middle Aged , Periodontal Diseases/complications , Periodontal Diseases/epidemiology , Periodontal Pocket/complications , Periodontal Pocket/epidemiology
2.
J Med Case Rep ; 13(1): 143, 2019 May 13.
Article in English | MEDLINE | ID: mdl-31082330

ABSTRACT

BACKGROUND: Calcium pyrophosphate dihydrate crystal deposition disease is a condition in which calcium pyrophosphate dihydrate crystal is deposited in joint cartilage and ligaments. Calcium pyrophosphate dihydrate crystal deposition disease that involves calcification around the odontoid process of the second cervical vertebra is called crowned dens syndrome. Crowned dens syndrome is accompanied by fever in addition to acute and intense neck, posterior head, and temporal pain; thus, distinguishing crowned dens syndrome may be difficult in the presence of odontogenic infection. To the best of our knowledge, this is the first report describing a patient with crowned dens syndrome with coexisting odontogenic infection. CASE PRESENTATION: A 75-year-old Japanese woman was examined in the Emergency Department of this hospital due to a chief complaint of worsened buccal swelling on the left side. An odontogenic infection was considered, and she underwent her first examination. She presented with a body temperature of 37.4 °C, marked swelling and tenderness of her left lower eyelid through to her left cheek, and pain on the left temporal area. Blood tests revealed a leukocyte count of 6700/µL and a C-reactive protein level of 7.15 mg/dL. There was swelling and pain around the gingiva and acute purulent apical periodontitis of left maxillary second premolar. Cellulitis of the left cheek was diagnosed. After performing drainage of the pus, antibiotic treatment was initiated. Although her clinical symptoms improved, blood tests on day 9 of hospitalization revealed a leukocyte count of 6500/µL and a C-reactive protein level of 25.62 mg/dL, which were indicative of worsening symptoms. Computed tomography was performed to evaluate remote infection and images revealed a calcification around the odontoid process of her second cervical vertebra. When she was referred to the Orthopedic Surgery Department, pseudogout of the cervical spine was diagnosed. Subsequently, oral acetaminophen was initiated, and both her leukocyte count and C-reactive protein improved markedly. CONCLUSIONS: In the presence of persistent fever and abnormally high leukocyte and C-reactive protein indicative of an inflammatory reaction, coexistence of pseudogout should be considered. In particular, when symptoms of temporal pain are present, the possibility of pseudogout of the cervical spine must be considered in the differential diagnosis.


Subject(s)
Calcium Pyrophosphate/adverse effects , Chondrocalcinosis/diagnosis , Odontoid Process/diagnostic imaging , Aged , Chondrocalcinosis/etiology , Female , Gingival Diseases/complications , Humans , Mouth Mucosa/microbiology , Neck Pain/etiology , Syndrome , Tomography, X-Ray Computed
3.
Oral Dis ; 25(5): 1335-1343, 2019 Jul.
Article in English | MEDLINE | ID: mdl-30947385

ABSTRACT

OBJECTIVES: The role of dental plaque in gingival lesions caused by oral lichen planus has not been fully defined. The aim of this clinical trial was to evaluate the effects of oral healthcare motivation on clinical variables in patients with gingival oral lichen planus. MATERIAL AND METHODS: Oral lichen planus patients with symptomatic gingival lesions were randomized in control and intervention groups. The intervention group was instructed to effectively remove bacterial biofilm from dental surfaces, while controls did not receive any advice. The outcome variables were as follows: quality of life (OHIP-14), pain, plaque index and clinical severity of the disease (Escudier index). Outcome variables were assessed at 0, 4 and 20 weeks and analysed using an ANOVA model for factorial design. RESULTS: Data from 60 patients were collected. Regression analysis showed a significant positive trend of OHIP-14, plaque index and Escudier index in the intervention group compared to controls (p < 0.05). Pain did not prove significantly different (p = 0.408). CONCLUSIONS: Plaque control improved both OHIP-14 and gingival lesion clinical severity. Oral hygienists should be involved in the multidisciplinary management of patients affected by oral lichen planus with gingival lesions.


Subject(s)
Dental Plaque/prevention & control , Gingival Diseases/complications , Lichen Planus, Oral/complications , Motivation , Oral Hygiene , Quality of Life/psychology , Dental Plaque Index , Humans , Oral Health , Prospective Studies
5.
RFO UPF ; 24(3): 408-412, 2019. tab
Article in Portuguese | LILACS, BBO - Dentistry | ID: biblio-1357703

ABSTRACT

Objetivo: o objetivo desta revisão integrativa crítica foi investigar a relação de fissuras labiopalatinas com doenças gengivais, correlacionando-as à qualidade de vida, de modo a fornecer esclarecimento sobre a temática, mesmo que sejam necessários mais estudos de acompanhamento longitudinal neste tema. Revisão de literatura: a Organização Mundial de Saúde define qualidade de vida correlacionada à condição bucal como a autopercepção do indivíduo sobre a influência de sua condição oral ­ em aspectos relacionados ao seu bem-estar geral, é plausível que ocorra associação com a doença periodontal, além disso, o possível impacto que tais condições podem desempenhar na vida dos indivíduos com fissura labiopalatina ainda é pouco conhecido, tornando-se relevante sintetizar dados dessa provável associação. Considerações finais: a presente revisão enfatizou a análise crítica de estudos transversais e longitudinais, supondo que a adequada compreensão das particularidades desses estudos favoreça o entendimento do impacto das doenças gengivais, associada a pacientes com fissura labiopalatina, e tendo como base que o entendimento desses fatores podem implicar no bem-estar da população estudada, servindo de auxílio na tomada terapêutica e no modo de agir do cirurgião-dentista. Portanto, mais estudos com qualidade metodológica são necessários nesta temática, podendo contribuir para uma definição mais clara da possível associação de piores escores de higiene a um impacto na qualidade de vida de indivíduos com fissura labiopalatina.(AU)


Objective: This critical integrative review aimed to investigate the relationship between cleft lip and palate and gingival diseases, correlating them to quality of life to provide clarification on the subject, even if further studies on long-term follow-up on this subject are required. Literature review: The World Health Organization defines oral health-related quality of life as the self-perception of individuals on the influence of their oral condition - in aspects related to their general well-being. It is likely associated with periodontal disease. Moreover, the impact that such conditions may have on the life of individuals with cleft lip and palate is still little known, making it relevant to synthesize the data of this potential association. Final considerations: The present review focused on the critical analysis of cross-sectional and longitudinal studies, assuming that an adequate appreciation of the particularities of these studies favors the understanding of the impact of gingival disease associated with patients with cleft lip and palate. The understanding of these factors may imply in the well-being of the population studied, aiding the therapeutic choice and the conduct of dentists. Therefore, further studies with methodological quality are required on this subject, which may contribute to a clearer definition of the potential association of worse hygiene scores with an impact on the quality of life of individuals with cleft lip and palate.(AU)


Subject(s)
Humans , Quality of Life , Cleft Lip/complications , Cleft Palate/complications , Gingival Diseases/complications , Oral Health , Observational Studies as Topic
6.
Community Dent Oral Epidemiol ; 46(6): 535-544, 2018 12.
Article in English | MEDLINE | ID: mdl-29971825

ABSTRACT

OBJECTIVES: Root caries has increased as a clinical problem in recent decades. However, the use of multiple waves of longitudinal follow-up data in estimating root caries increment has not been previously attempted. The aims of this study were to quantify root caries increment from a longitudinal study of older adults with 4 oral examinations over 11 years and to examine behavioural factors associated with root caries. METHODS: A secondary analysis was undertaken using data collected in 4 waves (baseline, 2-year, 5-year and 11-year) of the South Australian Dental Longitudinal Study which began in 1991/92. The study group consisted of a stratified random sample of people aged 60+ years at baseline. A total of 358 participants with complete oral examinations in all 4 waves were included. The examinations were performed by trained and calibrated dentists. Baseline behavioural risk factors (toothbrushing frequency, flossing frequency, dental visiting pattern, reason for dental visiting and tobacco smoking status) and time in years across the 4 waves were the main exposures. Baseline clinical oral conditions (gingival condition and gingival recession), demographic and socio-economic risk factors served as covariates. Root caries was measured as mean number of untreated root surfaces (root DS) and decayed/filled root surfaces (root DFS) at each wave of examinations. Multivariable multilevel growth model using linear regression analysis was used to get an estimate for root caries increment and associated oral health-related behaviours adjusting for all the covariates. RESULTS: Findings from the multivariable models indicated that the annual increment of root DS and root DFS were 0.07 (SE = 0.01) and 0.11 (SE = 0.02) surfaces, respectively. Irregular brushing (E [SE] = 0.25 [0.12]), visiting the dentist only for problems (E [SE] = 0.30 [0.13]) and smoking (E [SE] = 0.33 [0.12]) were risk factors for the increase in root DS. Irregular flossing and more frequent dental visit were associated with the increase in root DFS. CONCLUSIONS: Root caries increased slowly across time among relatively healthier Australian older adults. Irregular brushing, unfavourable dental visiting and tobacco smoking were risk factors for the increase in untreated root caries, while irregular flossing and more frequent dental visiting were associated with the increase in root DFS.


Subject(s)
Root Caries/epidemiology , Aged , Dental Devices, Home Care , Female , Gingival Diseases/complications , Gingival Diseases/epidemiology , Humans , Longitudinal Studies , Male , Middle Aged , Oral Hygiene , Risk Factors , Root Caries/etiology , Smoking/adverse effects , Socioeconomic Factors , South Australia/epidemiology , Toothbrushing
8.
J Intellect Disabil Res ; 62(3): 187-198, 2018 03.
Article in English | MEDLINE | ID: mdl-29114946

ABSTRACT

BACKGROUND: Several risk factors for cardiovascular disease (CVD) have been identified among adults with intellectual disabilities (ID). Periodontitis has been reported to increase the risk of developing a CVD in the general population. Given that individuals with ID have been reported to have a higher prevalence of poor oral health than the general population, the purpose of this study was to determine whether adults with ID with informant reported gum disease present greater reported CVD than those who do not have reported gum disease and whether gum disease can be considered a risk factor for CVD. METHODS: Using baseline data from the Longitudinal Health and Intellectual Disability Study from which informant survey data were collected, 128 participants with reported gum disease and 1252 subjects without reported gum disease were identified. A series of univariate logistic regressions was conducted to identify potential confounding factors for a multiple logistic regression. RESULTS: The series of univariate logistic regressions identified age, Down syndrome, hypercholesterolemia, hypertension, reported gum disease, daily consumption of fruits and vegetables and the addition of table salt as significant risk factors for reported CVD. When the significant factors from the univariate logistic regression were included in the multiple logistic analysis, reported gum disease remained as an independent risk factor for reported CVD after adjusting for the remaining risk factors. Compared with the adults with ID without reported gum disease, adults in the gum disease group demonstrated a significantly higher prevalence of reported CVD (19.5% vs. 9.7%; P = .001). CONCLUSION: After controlling for other risk factors, reported gum disease among adults with ID may be associated with a higher risk of CVD. However, further research that also includes clinical indices of periodontal disease and CVD for this population is needed to determine if there is a causal relationship between gum disease and CVD.


Subject(s)
Cardiovascular Diseases/epidemiology , Gingival Diseases/epidemiology , Intellectual Disability/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Cardiovascular Diseases/etiology , Comorbidity , Female , Gingival Diseases/complications , Health Surveys , Humans , Longitudinal Studies , Male , Middle Aged , Midwestern United States/epidemiology , Risk Factors , Young Adult
10.
Nat Rev Dis Primers ; 3: 17038, 2017 Jun 22.
Article in English | MEDLINE | ID: mdl-28805207

ABSTRACT

Periodontal diseases comprise a wide range of inflammatory conditions that affect the supporting structures of the teeth (the gingiva, bone and periodontal ligament), which could lead to tooth loss and contribute to systemic inflammation. Chronic periodontitis predominantly affects adults, but aggressive periodontitis may occasionally occur in children. Periodontal disease initiation and propagation is through a dysbiosis of the commensal oral microbiota (dental plaque), which then interacts with the immune defences of the host, leading to inflammation and disease. This pathophysiological situation persists through bouts of activity and quiescence, until the affected tooth is extracted or the microbial biofilm is therapeutically removed and the inflammation subsides. The severity of the periodontal disease depends on environmental and host risk factors, both modifiable (for example, smoking) and non-modifiable (for example, genetic susceptibility). Prevention is achieved with daily self-performed oral hygiene and professional removal of the microbial biofilm on a quarterly or bi-annual basis. New treatment modalities that are actively explored include antimicrobial therapy, host modulation therapy, laser therapy and tissue engineering for tissue repair and regeneration.


Subject(s)
Gingival Diseases/complications , Inflammation/blood , Periodontal Diseases/complications , Periodontitis/complications , Adult , Aggressive Periodontitis/complications , Anti-Bacterial Agents/therapeutic use , Biofilms/growth & development , Dental Plaque/complications , Dental Plaque/physiopathology , Dental Plaque/prevention & control , Female , Gingiva/pathology , Gingival Diseases/epidemiology , Gingival Diseases/physiopathology , Humans , Inflammation/complications , Microbiota/physiology , Oral Hygiene/methods , Periodontal Diseases/epidemiology , Periodontal Diseases/physiopathology , Periodontal Diseases/prevention & control , Periodontal Ligament/pathology , Periodontitis/epidemiology , Prevalence , Risk Factors , Tooth Loss/complications , Tooth Loss/etiology , Treatment Outcome
11.
Med. oral patol. oral cir. bucal (Internet) ; 22(2): e214-e218, mar. 2017. ilus, tab
Article in English | IBECS | ID: ibc-161239

ABSTRACT

BACKGROUND: Relapse of granulomatous epulis is common after surgery because of local irritations, hormonal level in vivo, or incomplete resection. Currently, if recurrence occurs, then extraction of the teeth adjacent to the lesion is commonly performed, which may influence the aesthetics or masticatory function. Thus, a more effective and less aggressive treatment method is urgently demanded, particularly for the recurring lesion. This study investigated the effects of the intralesional pingyangmycin (PYM) injections for the recurrent granulomatous epulis and assessed the complications. MATERIAL AND METHODS: A total of 16 patients with recurrent granulomatous epulis underwent intralesional PYM injections, between July 2010 and June 2014. The effects and complications of the treatment were retrospectively reviewed. RESULTS: The total number of injections performed was 48 (for all patients). The median number of injections per patient was three (range, two to four). All cases completely recovered with no recurrence and resorption of the alveolar bone after a follow-up of more than 12 months. The complications included slight bleeding, local swelling and pain following injection. All these symptoms resolved 7 to 10 days after the injection. CONCLUSIONS: In summary, intralesional PYM injections may be a preferred option for recurring granulomatous epulis


Subject(s)
Humans , Sclerotherapy/methods , Granulomatosis, Orofacial/surgery , Bleomycin/administration & dosage , Recurrence , Postoperative Complications , Gingival Diseases/complications , Injections, Intralesional/methods
12.
San Lorenzo; UPAP; 2017. [20] p. ilus.
Non-conventional in Spanish | BDNPAR | ID: biblio-914101

ABSTRACT

Las enfermedades gingiviales y perodontales son un conjunto de enfermedades producidas por microorganismos que afectan las estructuras que sostienen los dientes como; encía, ligamentos, huesos alveolar, hay dos grandes grupos de enfermedad de la encías: 1. La gingivitis, afecta solo la encía 2. La periodontitis,además de la inflamación de la encía, produce una destrucción profunda e irreversibles, que afecta al hueso alveolar, al cemento del diente y al ligamento periodontal.


Subject(s)
Humans , Adult , Oral Hygiene , Periodontics/methods , Dental Care , Guidelines as Topic/analysis , Gingival Diseases , Gingivitis , Periodontitis , Case Reports , Fluoridation , Dental Caries Activity Tests , Dental Prophylaxis , Gingival Diseases/complications , Gingivitis/blood
15.
Oral Health Prev Dent ; 14(1): 41-7, 2016.
Article in English | MEDLINE | ID: mdl-26106653

ABSTRACT

PURPOSE: To establish an inventory of knowledge, attitudes and daily pratice of dental and medical practitioners in France regarding oral health care and its relationship to pregnancy, particularly to preterm delivery and low birth-weight infants. MATERIALS AND METHODS: A questionnaire was distributed to health-care professionals (n= 460), consisting of 100 prenatal care practitioners (obstetricians, midwives) and 360 dentists, about their knowledge of oral alterations during pregnancy, the possible association between periodontal disorders and preterm/low birth weight, and their conduct toward their patients. RESULTS: Bleeding gums and pregnancy gingivitis were the oral manifestations most often cited by all the practitioners. In contrast, prenatal care practitioners were unaware of epulis and a greater percentage of them than dentists believed caries risk to increase during pregnancy. The most adverse pregnancy outcomes cited were risk of premature delivery and chorioamniotis. Only dentists had received initial training on pregnancy complications. Finally, all health professionals point out the lack of continuing education on this topic. CONCLUSION: The present results underline the need for a better initial professional education and continuing education regarding pregnancy and oral health conditions and emphasise the need to update the guidelines in health care practices for pregnant women for a more effective prevention of risk-related adverse pregnancy outcomes, such as pre-term birth or pre-eclampsia.


Subject(s)
Education, Dental , Gynecology/education , Midwifery/education , Obstetrics/education , Periodontal Diseases/complications , Pregnancy Complications , Attitude of Health Personnel , Chorioamnionitis/etiology , Dental Care , Female , France , Gingival Diseases/complications , Gingival Hemorrhage/complications , Gingivitis/complications , Humans , Infant, Low Birth Weight , Infant, Newborn , Practice Patterns, Dentists' , Practice Patterns, Physicians' , Pre-Eclampsia/etiology , Pregnancy , Pregnancy Outcome , Premature Birth , Prenatal Care
17.
J Laryngol Otol ; 129(6): 607-10, 2015 Jun.
Article in English | MEDLINE | ID: mdl-26074261

ABSTRACT

BACKGROUND: Pregnancy-associated pyogenic granuloma (pregnancy tumour) is not uncommon. However, control of severe bleeding associated with the lesion by transarterial embolisation has never been reported. CASE REPORT: We report the case of a 33-year-old pregnant woman (34 weeks gestation) who presented with a pregnancy-associated pyogenic granuloma of the mandibular gingiva with a life-threatening haemorrhage. The bleeding stopped soon after transarterial micro-embolisation and regressed after one month; thus, no further surgical excision was needed. The patient was free of post-operative wound pain and infection, and there was no recurrence after one year of follow up. CONCLUSION: In general, surgical excision is the first treatment choice for pregnancy tumours. However, it is limited by the risk of marked deformity or incomplete excision when large lesions or difficult surgical areas are encountered. For large tumours, transarterial embolisation may be a safer alternative.


Subject(s)
Embolization, Therapeutic/methods , Gingival Diseases/complications , Granuloma, Pyogenic/complications , Hemorrhage/therapy , Pregnancy Complications , Adult , Female , Hemorrhage/etiology , Humans , Pregnancy
18.
J Clin Periodontol ; 42(4): 356-62, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25728699

ABSTRACT

AIM: To evaluate the impact of a structured plaque control intervention on clinical and patient-centred outcomes for patients with gingival manifestations of oral lichen planus. MATERIALS AND METHODS: Eighty-two patients were recruited into a 20-week randomized controlled trial. The intervention was structured plaque control comprising powered tooth brushing and inter-dental cleaning advice. Control subjects continued with their normal dental plaque control regimen. The primary outcome measure was the oral health impact profile (OHIP) with secondary outcomes of pain, plaque index, mucosal disease score and cost-effectiveness. RESULTS: Overall, the intervention patients showed statistically significant improvements in OHIP sum ordinal and OHIP dichotomous scores compared with control. There were improvements in the functional limitation, psychological discomfort and physical disability domains at 4- and 20-weeks and in the psychological disability domain at 20-weeks. The intervention was successful in reducing plaque compared to control (p < 0.001) and improvements were observed using the mucosal disease indices at the 4- and 20-week follow-ups (p < 0.001). CONCLUSION: A structured plaque control intervention was effective in improving the oral health-related quality of life and clinically observed gingival lesions. This study provides evidence to include intensive plaque control within patients' initial and on-going management.


Subject(s)
Dental Plaque/prevention & control , Gingival Diseases/complications , Lichen Planus, Oral/complications , Attitude to Health , Dental Devices, Home Care , Dental Plaque Index , Equipment Design , Female , Follow-Up Studies , Gingival Diseases/classification , Humans , Lichen Planus, Oral/classification , Longitudinal Studies , Male , Middle Aged , Oral Health , Oral Hygiene/education , Oral Hygiene/instrumentation , Pain Measurement/methods , Patient-Centered Care , Quality of Life , Toothbrushing/instrumentation , Treatment Outcome
20.
Article in English | MEDLINE | ID: mdl-25532099

ABSTRACT

Even from the distant past the aesthetic perception in an individual was diminished by the presence of gap between the central incisors. This condition is found under the term "dents du bonheur" or "lucky teeth" and is encountered even among world famous figures including Brigitte Bardot, Eliah Wood, Madonna, Zac Efron, Amy Winehouse and Elton John. The teeth gaps are still considered main reasons for dissatisfaction of the dental patients and reasons for the requirement of aesthetic treatment. The purpose of this study is to exhibit the influence of the etiological factors in the occurrence of diastema mediana classified according to the dominance of their occurrence expressed in percentage values. Materials of this investigation were 100 patients with diastema mediana from the following factors: inheritance, disproportion in the dental arches, inborn or acquired missing teeth, harmful oral habits, high insertion of the labial frenulum as well as mesiodens. After the diagnosis and evaluation of the etiological factor for diastema mediana was performed, a decision regarding the course of treatment was made in direction of the removal of the etiological factor at an early age and orthodontic treatment. The end of the orthodontic treatment in a group of the patients was the beginning of prosthodontic reconstruction. From our clinical investigation we came to the realization that in 49 patients (49%) the hereditary influence was a dominant factor, next followed disproportions and discrepancies in the dental arch in 14 (14%), inborn or acquired missing teeth in 11 patients (11%), harmful oral habits in 10 (10%), high frenulum insertion in 4 (4%), and pathological objects between central incisors, mesiodens, iatrogenic factors and periodontal disease, in 3 of the clinical cases (3%) each. We concluded that the occurrence of diastema mediana is multi-causal. The dominant place is occupied by the hereditary factors. With regard to the mutual relationship between the multitudes of factors in the occurrence of diastema mediana, the diagnosis should be made conciliary and the clinical treatment should be interdisciplinary including a prosthodontist, orthodontist and oral surgeon.


Subject(s)
Anodontia/complications , Diastema/etiology , Orthodontics, Corrective/methods , Tooth Loss/complications , Dental Arch/pathology , Diastema/therapy , Gingival Diseases/complications , Humans
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