Subject(s)
Glossitis , Humans , Glossitis/etiology , Glossitis/drug therapy , Antiviral Agents/therapeutic useABSTRACT
Vitamins are organic compounds present in low concentrations in food, performing vital and specific cell metabolism functions. Vitamin B12 is essential for red blood cell formation in the bone marrow and its deficiency is caused, mainly, by gastrointestinal malabsorption. In addition to systemic manifestations, oral signs and symptoms have also been associated to this condition such as glossitis, papillary atrophy, painful erythema areas, burning sensation, dysgeusia, lingual paresthesia and itching. This study aims to report four cases of oral manifestations caused by vitamin B12 deficiency. All patients presented oral mucosa lesions. Vitamin B12 deficiency was diagnosed based in clinical characteristics and complementary exams. Oral supplementation for vitamin B12 deficiency was conducted/realized in three patients, while one patient was treated with parenteral doses. All of them showed partial or total remission of the signs and symptoms.
Subject(s)
Glossitis , Tongue Diseases , Vitamin B 12 Deficiency , Glossitis/complications , Glossitis/drug therapy , Humans , Vitamin B 12/therapeutic use , Vitamin B 12 Deficiency/complications , Vitamin B 12 Deficiency/diagnosis , Vitamin B 12 Deficiency/drug therapySubject(s)
Humans , Male , Adult , Female , Middle Aged , Glossitis/diagnosis , Glossitis/pathology , Fluconazole/therapeutic use , Glossitis/drug therapyABSTRACT
Herpes simplex virus (HSV) infections in an immunocompromised host may be atypical in location and morphology. Lesions are more extensive and aggressive, slow healing or nonhealing and extremely painful. Intraoral lesions are ulcerative and may involve any intraoral, oropharyngeal, or esophageal site. Herpetic geometric glossitis is a recently described form of lingual HSV infection in an immunocompromised patient. It was described as ulcer on the dorsum of the tongue sensitive for acyclovir therapy. A patient is presented with acute myelogenous leukemia that developed herpetic geometric glossitis which was acyclovir resistant.
Subject(s)
Acyclovir/therapeutic use , Antiviral Agents/therapeutic use , Glossitis/drug therapy , Glossitis/virology , Herpes Simplex/diagnosis , Herpes Simplex/drug therapy , Leukemia, Myeloid, Acute/complications , Drug Resistance, Viral , Humans , Male , Middle Aged , Tongue/pathology , Treatment FailureABSTRACT
Oral soft tissue lesions, which clinically appear red, are common. These lesions may present themselves in different clinical forms. They may be patchy, spotted, macular, papular, nodular, localized, diffuse, single, multiple and so on. Lesions that appear red may be considered primary when they appear when they appear as a result of local causes. They are secondary when their occurence is a result of systemic pathology. It is not uncommon that red lesions may be associated with pigmented or white lesions. In this chapter, commonly encountered red lesions of the oral mucosa are briefly discussed (AU)