The Stroke Unit Story: Where Have We Been and Where Are We Going?

BACKGROUND: The concept of stroke unit care has been discussed for over 50 years, but it is only in the last 25 years that clear evidence of its effectiveness has emerged to inform these discussions. SUMMARY: This review outlines the history of the concept of stroke units to improve recovery after stroke and their evaluation in clinical trials. It describes the first systematic review of stroke unit trials published in 1993, the establishment of a collaborative research group (the Stroke Unit Trialists' Collaboration), the subsequent analyses and updates of the evidence base, and the efforts to implement stroke unit care in routine settings. The final section considers some of the remaining challenges in this area of research and clinical practice. Key Messages: Good quality evidence confirms that stroke patients who are looked after in a stroke unit are more likely to survive and be independent and living at home 1 year after their stroke. The apparent benefits are independent of patient age, sex, stroke type, or initial stroke severity. The benefits are most obvious in units based in a discrete ward (stroke ward). The current challenges include integrating effective stroke units with more recent systems to deliver hyper-acute stroke interventions and implementing stroke units in lower resource regions.

Historical High Complexity Neurosurgery Development of One of the Poorest Brazilian Regions

Human development rates in the Vale do Jequitinhonha, state of Minas Gerais, Brazil, called "Misery Valley," are among the lowest in the country, not to mention the often precarious psychosocial realities that daily contact with these families reveals. The history of neurosurgery at the Neurosurgical Reference Center at the Vale do Jequitinhonha e Mucuri dates from 2004, when the first neurosurgical procedures were performed in the recently organized Section of Neurosurgery. The historical surgical series shows the positive impact of the service. In 2007, the average was 3 neurosurgeries/month. In the last year, 2018, service growth boosted the record to 34.83 neurosurgeries/month. In addition to performing elective surgery, the neurosurgery team supports the emergency team by performing some neurosurgical procedures. The service number of patients operated since the development of the service is nearly 3,000. Neurosurgery at the Santa Casa de Caridade from Diamantina has been made comparable to the best national neurosurgery services.

Closed venereology wards in postwar Hamburg.

BACKGROUND: A number of research results on closed venereology facilities in the Soviet Occupation Zone (SOZ) and the German Democratic Republic (GDR) have been presented in recent years. However, little is known about similar facilities in the Western Occupation Zones (WOZ) and in the early Federal Republic of Germany (FRG). METHOD: We have researched the records of the State Archive in Hamburg. Subsequently, the analysed sources were evaluated using the historically critical method. RESULTS: Three closed venereology wards existed in Hamburg. Compulsory commitments were conducted according to a three-stage procedure. In the immediate postwar period, the wards had barred windows and the doors were locked. Everyday life in the wards was initially determined by the postwar situation - poor facilities, poor hygiene, overcrowding. In the early 1950s, the number of beds was drastically reduced. The function of the wards consisted of isolation and medical care for the compulsorily committed persons. Medical care was in accordance with professional medical standards. DISCUSSION: Closed venereology wards in Hamburg followed the tradition established during the period of the Weimar Republic. This becomes apparent both in terms of the legal framework and in terms of the structure and functions of the wards. Thus, they clearly differ from the closed venereology facilities in the SOZ and in the GDR. These facilities were established in the tradition of Soviet prophylactics institutions. The wards in Hamburg served as isolation and treatment centres, the facilities in the SOZ and in the GDR also had a disciplinary function.

50 years of Hepatology: The Royal Free Hospital School of Hepatology.

Writing about the history of Hepatology would necessarily imply writing about the history of the Liver Unit and the School of Hepatology created by Dr. Sheila Scherlock at the Royal Free Hospital (London). On the 70th anniversary of the creation of the first liver unit (Hammersmith Hospital) this article presents a brief account of the history, organization, structure, educational program and contributions of perhaps the first and the most influential medical research models created for the study of liver diseases: the Royal Free Hospital Liver Unit.

La asistencia sanitaria a los heridos y enfermos del exilio republicano español en Francia: de la improvisación inicial a los campos de concentración (enero-septiembre 1939) / Healthcare to wounded and sick refugees in the spanish republican exile in france: from the initial improvisation to the concentration camps (january-september 1939)

El final de la Guerra Civil Española en Cataluña supuso un punto de inflexión en la vida de casi medio millón de refugiados españoles que traspasaron la frontera pirenaica en el invierno de 1939. En este gran afluente, existieron más de 13.000 heridos y enfermos que tuvieron que ser atendidos por toda la geografía francesa. Con esta investigación, se visibiliza cuáles fueron los itinerarios de los heridos, dónde fueron atendidos y qué características tuvo la asistencia sanitaria hasta que la mayoría de los pacientes fueron reconducidos a campos de concentración situados en el sur de Francia. Nos encontramos ante una realidad compleja que ha sido abordada con documentación localizada en una docena de archivos históricos franceses, testimonios directos y prensa general. Entre los resultados, cabe destacar la necesidad de improvisación de la III República Francesa en materia asistencial, ya que el 70% de los refugiados fueron asistidos en centros acondicionados para la ocasión. En los hospitales, quienes atendieron fueron en su mayoría profesionales sanitarios españoles. Realizaron su labor de una manera digna, a pesar de las restricciones de las autoridades francesas hacia lo que ellos consideraron "el problema español"

The end of the Spanish Civil War in Catalonia influenced the lives of almost half a million of Spanish refugees that crossed the Pyrenean border in the winter of 1939. In this large migration wave, more than 13,000 wounded and sick people had to be treated within French territory. With this research, we examine the routes of the wounded, the places where they were treated, and the features of their healthcare before they were transported to the concentration camps in southern France. This information has been analysed using documentation of 12 French historical archives, direct testimonials and general press. The results emphasize the Third French Republic’s ability to improvise in the healthcare field, where 70% of the refugees were treated in specially equipped healthcare centres. Those who treated refugees in hospitals were mostly Spanish healthcare professionals. They carried out their work in a dignified manner, despite restrictions from French authorities towards what they considered to be "the Spanish problem"

George Riddoch (1888-1947): the driving force behind the treatment of spinal injuries in the UK during the Second World War.

The development of the successful treatment of spinal injuries has been inextricably linked to Sir Ludwig Guttmann and Stoke Mandeville Hospital. The role of George Riddoch has largely been ignored or mentioned merely in relation to Ludwig Guttmann and his appointment as the first Resident Medical Officer at Stoke Mandeville Hospital. Riddoch's contribution was far more significant. New material, comprising Riddoch's letters and memoranda written between 1939 and 1944, reveals his paramount involvement in the setting up of spinal injury units across the UK between 1941 and 1944, and his skill as an administrator and a clinician. Riddoch must be given credit for finding and appointing Ludwig Guttmann.

History, Principles, and Policies of Observation Medicine.

The history of observation medicine has paralleled the rise of emergency medicine over the past 50 years to meet the needs of patients, emergency departments, hospitals, and the US health care system. Just as emergency departments are the safety net of the health system, observation units are the safety net of emergency departments. The growth of observation medicine has been driven by innovations in health care, an ongoing shift of patients from inpatient to outpatient settings, and changes in health policy. These units have been shown to provide better outcomes than traditional care for selected patients.

The controversy over the restructuring of perinatal emergency services in Portugal and the importance of citizen participation in health care decision-making processes.

This article explores the controversial decision made by the Ministry of Health to restructure the perinatal emergency services in Portugal in 2006. Particular emphasis is given to the protests held across the country against, the actors involved, and the arguments put forward for and against the measure, in an attempt to understand the forms of knowledge and experiences brought to the discussion about the issues raised by the decision, and how different forms of knowledge are reconciled under a democratic process. In addition, this article explores the importance of citizen participation, including that which emerges from conflicting relations, in the formulation of health policies.

The controversy over the restructuring of perinatal emergency services in Portugal and the importance of citizen participation in health care decision-making processes / A controvérsia sobre a restruturação dos serviços de urgência perinatal em Portugal e a importância da participação cidadã em processos de decisão sobre saúde

This article explores the controversial decision made by the Ministry of Health to restructure the perinatal emergency services in Portugal in 2006. Particular emphasis is given to the protests held across the country against, the actors involved, and the arguments put forward for and against the measure, in an attempt to understand the forms of knowledge and experiences brought to the discussion about the issues raised by the decision, and how different forms of knowledge are reconciled under a democratic process. In addition, this article explores the importance of citizen participation, including that which emerges from conflicting relations, in the formulation of health policies.

O artigo examina o processo de restruturação dos serviços de emergência perinatal implementado pelo Ministério da Saúde em Portugal em 2006 e tem como objetivo analisar essa decisão controversa. Especial ênfase é dada aos protestos desencadeados no país contra essa medida, os atores envolvidos e os argumentos contra e a favor, de forma a compreender os conhecimentos e as experiências trazidos para discussão dos problemas suscitados pela decisão tomada e como diferentes formas de conhecimento podem ser conciliadas no âmbito de procedimentos democráticos. Além disso, explora a relevância da participação cidadã na formulação de políticas de saúde, incluindo aquela que emerge de relações conflitantes.

Joint geriatric and old-age psychiatric wards in the U.K., 1940s-early 1990s: a historical study.

OBJECTIVE: This study aims to investigate the history of joint geriatric-psychiatric units. For policy making and planning of high-quality clinical service models, clinical and social contexts need to be considered. Longitudinal, contextual information can be provided by historical analyses, including the successes and failures of earlier, similar services. Historical analyses complement clinical, randomised controlled studies and may contribute to ensuring optimum outcomes for future schemes. METHODS: Standard historical methodology was used, including searching published sources and institutional and personal archives and conducting a 'witness seminar' and individual oral history interviews. RESULTS: Proposals to create joint units have existed since 1947. Most clinically successful units were led by enthusiastic, dedicated clinicians. Joint units had the potential to provide appropriate assessment and treatment for patients with multiple disorders and education for staff and students. Joint units never became widespread. CONCLUSIONS: Reasons for the limited success of joint geriatric-psychiatric units might have included personalities of individuals, administrative boundaries separating geriatrics and medicine, unequal numbers of geriatricians and old-age psychiatrists, varying professional ideologies about the meaning of 'integrated' services, lack of reciprocity for each other's inpatients and lack of government support. Identified stumbling blocks need to be considered when planning joint clinical schemes. If current research indicates benefits of integrated wards for patients and their families, there needs to be ways to ensure that personal factors and fashions of management or government re-prioritisation will not lead to their premature termination.

The Kent hospital Wound Recovery and Hyperbaric Medicine Center: a brief overview, 1998-2013.

A brief description of the Wound Recovery and Hyperbaric Medicine Center, now in its second decade of service, will inform the general medical community of this valuable asset. Demand for wound care services is predicted to grow steadily over the next several decades. Kent Hospital's vision for wound care is embodied in its thriving Wound Recovery and Hyperbaric Medicine Center. New cost- effective wound healing therapies must be developed and evidence-based practices established. New physicians and support staff must be trained. Only through a blending of high quality clinical care with research and education will these objectives be achieved and future successes in the management of patients and their wounds be made possible.

Cincuenta años del Servicio de Angiología y Cirugía Vascular del Hospital Universitario Central de Asturias (HUCA) de Oviedo (1963-2013). Primer servicio asistencial y docente de España / Fifty years of the Angiology and Vascular Surgery Department in the Central Asturias University Hospital (HUCA) in Oviedo (1963-2013). First healthcare and teaching department in Spain

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Franc D. Ingraham and the genesis of pediatric neurosurgery.

In 1929, Franc D. Ingraham, Harvey Cushing's protégé, established the first pediatric neurosurgical unit in the world at Boston Children's Hospital and dedicated his career to the neurosurgical care of children. He trained with both Cushing and Dandy and spent 1 year working in Oxford with Sherrington, who considered Ingraham to be the finest operative surgeon ever to work in his laboratory. Ingraham was instrumental in developing novel treatments, which he compiled in his classic book, Neurosurgery of Infancy and Childhood. Although he was modest and shy, Ingraham loved to entertain children with magic and enjoyed photography in and out of the operating room. Unfortunately, his career was plagued by personal illness, and he died young in 1965 at the age of 67. Despite his prolific 36-year neurosurgical career, Ingraham remained an associate professor at Harvard at his retirement. To recognize his remarkable contributions, Harvard established an endowed chair in his name in 1967. Ingraham was a pioneer and a leader in the development of pediatric neurosurgery by virtue of his imagination, intelligence, and ability to lead and inspire others. Cushing has come to be regarded as the founder of neurosurgery. It is fair to conclude that Ingraham, his disciple, is the founder of pediatric neurosurgery.

Semmelweis: de médicos: estetoscopios: corbatas y otros atuendos / Semmelweis: about physicians: athetoscopes: neckties and other garments

Por la heroica historia de Ignaz Semmelweis (1818-1865), los médicos hemos sido aconsejados a lavarnos las manos cada vez que examinamos un paciente. Deberíamos hacerlo antes y después, y estar seguros de que él nos viera… Una manifiesta y justificada cruzada a favor de la limpieza de los estetoscopios y contra del uso de batas blancas. Corbatas y otras prendas de vestir, ha venido expresándose en ambientes médicos, primero en forma tímida y ahora con mayor fuerza, al aportarse pruebas convenientes acerca de la inconveniencia de llevarlas. La consigna es la eliminación de las corbatas durante la visita o revistas médicas al considerárselas como diseminadoras de infecciones adquiridas en el hospital. Las corbatas más que un probable reservorío de gérmenes son prendas innecesarias por lo que el médico debe reconocer su eventual riesgo. Las nuevas guías de la Brithish Medical Association incluyen un mayor énfasis en el lavado de las manos y de acuerdo a ella, “es la intervención más importante en el control de las infecciones”. Igualmente, se aboga por un mejor diseño de las salas de hospitalización, mejor provisión de lavamanos o geles antisépticos, políticas más inteligentes en la prescripción de antibióticos y eliminar el uso de ítems tales como corbatas, a veces usadas continuamente y por semanas y solo por raridad enviadas a la lavandería

Since the heroic history of Ignaz Semmelweis (1818´1865), we doctors have been advised to wash our hands every time we examine a patient. We should have to do it before and sfter, and be sure that the patients is seeing us… An overt and warranted crusade in favor of cleaning stethoscopes and against the use of medical gowns, neckties and other clothing items has begun expressing itselfin medical spheres, first in timed form and now with greater force, thanks to convincing test regarding the inconvenience of their use. The main message is the alimination of neckties during examinations or medical rounds, considering that these are vehicles of infection acquired in the hospital. Neckties, more than probable reservoirs of germs, are unnecessary clothing items, reason why doctors must recognize their possible risk. The new guidelines of the Medical Brithish Association include a greater emphasis on the washing of hands and according to it, “(it) is the most important intervention in the control of infections”. Also, it pleads for a better design of hospital rooms, better provision of sink and/or antiseptic gels, more intelligent policies for antibiotic prescriptions and the elimination of the use of items such as neckties, sometimes used continuously and for weeks and only rarely washed

Stroke units: many questions, some answers.

BACKGROUND: The development of specialized stroke units has been a landmark innovation in acute stroke care. However, the high scientific evidence level for the recommendation for stroke units to provide clinical attention for acute stroke patients does not correspond to the level of stroke unit implementation. A narrative, nonsystematic review on published studies on stroke units was conducted, with special emphasis on those demonstrating their efficacy and effectiveness. We also attempt to provide some answers to several open questions regarding practical issues of stroke units. SUMMARY OF REVIEW: Stroke units represent the most efficacious model for care provision compared with general ward care and stroke teams. Every stroke patient can benefit from stroke unit care. These units are efficient, cost-effective and their benefits are consistent over time. Compared with other specific stroke therapies such as aspirin or intravenous thrombolytic agents, stroke units have a higher target population and higher benefit in terms of number of deaths and/or dependencies avoided. New approaches in stroke unit management such as the implementation of noninvasive monitoring or alternative clinical pathways could improve their benefit even further. CONCLUSION: Stroke units are cost-effective and need to be considered as a priority in health-care provision for stroke patients.

Relato histórico de la infectología española / History of Infectious Diseases in Spain

En el presente manuscrito se hace un breve resumen de lo que ha sido la historia de la infectología en España. Se consideran cuatro secciones referidas, en primer lugar, a los orígenes de una especialidad fruto de la necesidad de contar con expertos que dieran solución de una forma práctica y moderna a los diferentes problemas planteados por los pacientes con enfermedades infecciosas. En segundo lugar, la aparición del sida al comienzo de los años ochenta dio lugar a un enorme florecimiento en el campo de las enfermedades infecciosas, que trajo consigo la creación de unidades específicas dedicadas no sólo al control de los problemas asociados directamente con la infección por el virus de la inmunodeficiencia humana, sino al tratamiento de las infecciones oportunistas con comitantes. En tercer lugar, en estos últimos años ha despuntado de forma alarmante el problema de la infección nosocomial, problema de plena actualidad que obliga a la presencia de infectólogos expertos en este campo. Finalmente, la emigración y los viajes han requerido de los especialistas en enfermedades infecciosas una formación especial en salud internacional, lo que acrecienta la importancia de la disciplina de infectología (AU)

This paper includes a brief summary of the clinical historyof the diagnosis and treatment of infectious diseases in Spain. Firstly, the origins of a specialty arising from the need for specialists to attend to, in a practical and modern form, the different health problems of patients affected by infectious diseases, are described. Secondly, the appearance of AIDS, at the beginning of the 1980’s, prompted the creation of specific units dedicated to the care of problems associated with human immunodeficiency virus (HIV) infection and the concomitant opportunistic infections arising from the immunodeficiency arising from the HIV infection. Thirdly, in the last decades and even today, nosocomial infections have appeared as an alarming problem, needing the presence of specialist physicians in this field. Finally, emigration and international travel require specialists ininfectious diseases with specific expertise in international health, once more highlighting the importance of the specialty of Infectious Diseases (AU)