Relationship between main reproductive parameters and productivity traits in dairy cows / Relação entre os principais parâmetros reprodutivos e características de produtividade em vacas leiteiras

The objective of this study was to determine relationship between Lithuanian dairy cow breed productive and reproductive traits. The study was carried out with 586 fully completed lactation cows: 184 Lithuanian Holstein (H), 320 Lithuanian Black and White (LBW) and 82 Lithuanian Red (LR) cows (291 cows in I, 149 in II and 146 in III and older lactations). Cow productivity and reproduction traits were calculated. H cows in I lactation had a lower insemination index compared to the LR, shorter calving interval (P≤0.05) and service period (P≤0.05) than LBW cows. LBW cows produced 1440.46kg more milk (P≤0.05) with less milk fat and protein content (accordingly 0.28 and 0.22 percent) (P≤0.05) compared with the LRd. The service period of LBW older lactation cows was 21.38 days longer and the insemination index was 0.68 times higher compared to the I lactation cows (P<0.05). LR cows of III and older lactations produced 3742kg more milk (P≤0.05) compared with the I lactation. All cows from 131 and more service period days produced 1420kg more milk with 0.51 percent less fat (P≤0.05) and 0.1 percent less protein than cows with the service period from 91 till 110 days (P≤0.05).

O objetivo deste estudo era determinar a relação entre características produtivas e reprodutivas de vacas leiteiras lituanas. O estudo foi realizado com 586 vacas em lactação totalmente completas: 184 vacas Holstein (H) lituanas, 320 vacas Preto e Branco (LBW) lituanas e 82 vacas Vermelhas (LR) lituanas (291 vacas da raça I, 149 da raça II e 146 da raça III e lactações mais velhas). Foram calculadas a produtividade e as características de reprodução das vacas. As vacas da vaca H da vaca em lactação I tinham um índice de inseminação menor em comparação com a LR, intervalo de parição mais curto (P≤0,05) e período de serviço (P≤0,05) do que as vacas LBW. As vacas LBW produziram 1440,46 kg a mais de leite (P≤0,05) com menos gordura láctea e teor de proteína (consequentemente 0,28 e 0,22 por cento) (P≤0,05) em comparação com a LRd. O período de serviço das vacas de lactação LBW mais velhas foi 21,38 dias mais longo e o índice de inseminação foi 0,68 vezes maior em comparação com as vacas de lactação I (P<0,05). As vacas LR de lactação III e mais velhas produziram 3742 kg mais leite (P≤0,05) em comparação com a I lactação. Todas as vacas de 131 e mais dias de serviço produziram 1420kg mais leite com 0,51% menos gordura (P≤0,05) e 0,1% menos proteína que as vacas com o período de serviço de 91 a 110 dias (P≤0,05).

Pulmonary Coccidioidomycosis: A Case Report and Literature Review.

Coccidioidomycosis is an infectious disease caused by Coccidioides immitis or C. posadasii fungus. Humans usually get infected by inhaling spores risen from the soil. Although in 60 percent of cases symptoms are absent, remaining patients can develop various manifestations of the disease, from flu-like symptoms to severe dissemination or meningitis. In endemic regions (California, Arizona, Mexico, Central, and South America), pulmonary coccidioidomycosis causes 25% of community-acquired cases of pneumonia. We present the first registered case of pulmonary coccidioidomycosis in Lithuania. Clinical presentation, pathogenesis, treatment options, and diagnostic alternatives are discussed.

Bernard Lown y el arte de sanar / Bernard Lown and the art of healing

RESUMEN: Se presenta una semblanza del Dr. Bernard Lown, uno de los más destacados cardiólogos del siglo XX. Muy relevantes fueron sus estudios sobre arritmias ventriculares e isquemia miocárdica, como también la influencia del estrés sobre el umbral de la fibrilación ventricular. Simultáneamente con otros investigadores europeos desarrolló el cardiovertor eléctrico. Se releva particularmente su condición de gran clínico y el trato humano con sus pacientes. Finalmente, se destaca su contribución a evitar una guerra nuclear por lo cual, junto al Dr Chazov, recibió el Premio Nobel de la Paz.

ABSTRACT: This is a biographical note on Bernard Lown MD, recently deceased. He was one of the foremost cardiologist in the XXth century. Relevant were his studies on ventricular arrhythmias and myocardial ischemia, as well the effect of mental stress in lowering the ventricular arrhythmia threshold. Along with European researchs he developed the electric cardiovertor. Special emphasis is placed on his skills as a clinician and is humane approach to patient care. He contributed to international efforts to prevent nuclear war. For this effort he was awarded, along with Dr Chazov, the Nobel Peace Price.

Taming the pandemic? The importance of homemade plant-based foods and beverages as community responses to COVID-19.

Household responses to COVID-19 in different corners of the world represent the primary health care that communities have relied on for preventing and mitigating symptoms. During a very complex and confusing time, in which public health services in multiple countries have been completely overwhelmed, and in some cases even collapsed, these first-line household responses have been quintessential for building physical, mental, and social resilience, and for improving individual and community health. This editorial discusses the outcomes of a rapid-response preliminary survey during the first phase of the pandemic among social and community contacts in five metropolises heavily affected by the COVID-19 health crisis (Wuhan, Milan, Madrid, New York, and Rio de Janeiro), and in twelve rural areas or countries initially less affected by the pandemic (Appalachia, Jamaica, Bolivia, Romania, Belarus, Lithuania, Poland, Georgia, Turkey, Pakistan, Cambodia, and South Africa). We summarized our perspectives as 17 case studies, observing that people have relied primarily on teas and spices ("food-medicines") and that there exist clear international plant favorites, popularized by various new media. Urban diasporas and rural households seem to have repurposed homemade plant-based remedies that they use in normal times for treating the flu and other respiratory symptoms or that they simply consider healthy foods. The most remarkable shift in many areas has been the increased consumption of ginger and garlic, followed by onion, turmeric, and lemon. Our preliminary inventory of food medicines serves as a baseline for future systematic ethnobotanical studies and aims to inspire in-depth research on how use patterns of plant-based foods and beverages, both "traditional" and "new", are changing during and after the COVID-19 pandemic. Our reflections in this editorial call attention to the importance of ethnobiology, ethnomedicine, and ethnogastronomy research into domestic health care strategies for improving community health.

Control perceptions in epilepsy: A transcultural case-control study with focus on auras.

OBJECTIVE: General Locus of Control (GLoC) is used to measure the extent to which people perceive life events as results of their own actions or external factors. This study analyzes the relationship between GLoC and people with epilepsy's (PWE) clinical characteristics, levels of anxiety, depression, religiosity/spirituality, and quality of life, with particular attention to possible influences of auras. METHODS: A case-control study was carried out with 186 consecutive patients with a definite diagnosis of epilepsy in Brazil and Lithuania. Besides clinical and demographic data, all patients answered to internationally validated scales: Rotter's GLoC, Hospital Anxiety and Depression Scale (HADS), Quality of Life in Epilepsy (QOLIE-31), and Index of Core Spiritual Experiences-Revised (INSPIRIT-R). RESULTS: Patient's mean age was 36.15 ±â€¯13.75 years, 61.3% were female, mean age at onset of epilepsy was 17.27 ±â€¯13.59 years, and monthly seizure frequency was 8.22 ±â€¯20.00. People with epilepsy were more depressed than controls, (p = 0.03). Within the group with epilepsy, patients reporting auras and reacting to them had higher levels of depression (p = 0.002) and anxiety (p = 0.004) and lower QOLIE-31 (p = 0.01) score but did not differ in GLoC (p = 0.73) or INSPIRIT-R (p = 0.71). Patients with perceived ability to prevent seizures in response to auras had no increased levels of depression and anxiety. CONCLUSIONS: General Locus of Control externalization in PWE was not confirmed. To perceive and be able to react to auras is associated with increased anxiety and depressive symptoms in PWE but not if it results in preventing seizures. No transcultural differences in these parameters were found.

Skin diseases in internationally adopted children.

Internationally adopted children often present diseases contracted in the country of origin. Skin diseases are common in new arrivals, and diagnosis may prove challenging for GPs or even dermatologists if they are inexperienced in the extensive geographic and ethnic diversity of international adoptees. To analyse the frequency and characteristics of skin diseases in international adoptees. In total, 142 adoptees were evaluated for a cross-sectional cohort study. The most frequent diseases observed at arrival were dermatological conditions. Of the adoptees, 70% presented at least one skin disease, of which 57.5% were infectious; Tinea capitis being the most frequent (n = 42). The recovery rate of Tinea capitis was 89% (n = 32/36). Ten cases of scabies were diagnosed. Other diseases included viral skin infection (n = 22), with 16 cases of Molluscum contagiosum and bacterial infection. Skin diseases are very common in internationally adopted children. There is a need for close collaboration between dermatologists and paediatricians to diagnose such infections, as well as clear guidelines to treat them.

Self-reported physical inactivity and health complaints: a cross-sectional study of Lithuanian adolescent schoolgirls.

The study aimed to investigate the associations between physical inactivity and health complaints in relation to posttraumatic stress (PTS) symptoms, behavioral and nutritional factors, and sense of coherence (SOC) in eighth-grade girls enrolled in secondary schools in Kaunas, Lithuania. A random sample of girls (N = 862) was interviewed anonymously on health complaints, physical activity level, PTS symptoms, Antonovsky's SOC scale, health behaviors, and dietary patterns. All health complaints were significantly associated with physical inactivity. Crude odds ratio (OR) for physical inactivity and health complaints was 1.67 (95%CI: 1.09-2.56); after adjusting for PTS symptoms, the OR decreased to 1.57 (95%CI: 0.95-2.45); further adjustment for smoking, daily alcohol intake, daily consumption of fresh vegetables, and SOC decreased the OR to 1.25 (95%CI: 0.76-2.04). The effect of PTS symptoms and sense of coherence remained stable after all adjustments. The significant association between physical inactivity and health complaints was mediated by PTS symptoms.

Self-reported physical inactivity and health complaints: a cross-sectional study of Lithuanian adolescent schoolgirls / Autorrelato de queixas de inatividade e saúde física: um estudo transversal entre adolescentes / Autoinforme sobre la inactividad física y quejas de salud: un estudio transversal entre las adolescentes

The study aimed to investigate the associations between physical inactivity and health complaints in relation to posttraumatic stress (PTS) symptoms, behavioral and nutritional factors, and sense of coherence (SOC) in eighth-grade girls enrolled in secondary schools in Kaunas, Lithuania. A random sample of girls (N = 862) was interviewed anonymously on health complaints, physical activity level, PTS symptoms, Antonovsky’s SOC scale, health behaviors, and dietary patterns. All health complaints were significantly associated with physical inactivity. Crude odds ratio (OR) for physical inactivity and health complaints was 1.67 (95%CI: 1.09-2.56); after adjusting for PTS symptoms, the OR decreased to 1.57 (95%CI: 0.95-2.45); further adjustment for smoking, daily alcohol intake, daily consumption of fresh vegetables, and SOC decreased the OR to 1.25 (95%CI: 0.76-2.04). The effect of PTS symptoms and sense of coherence remained stable after all adjustments. The significant association between physical inactivity and health complaints was mediated by PTS symptoms.

O estudo tem como objetivo investigar a associação entre queixas de inatividade e saúde física em relação ao transtorno do estresse pós-traumático (TEPT), sintomas comportamentais e fatores nutricionais, bem como o senso de coerência (SOC) entre alunas da oitava série. Uma amostra aleatória de alunas (N = 862) foi entrevistada anonimamente sobre: queixas de saúde, nível de atividade física, sintomas de TEPT, escala SOC de Antonovsky, comportamentos de saúde e padrões alimentares. Todas as queixas de saúde foram significativamente associadas à inatividade física. A razão de odds (OR) não ajustada de inatividade física para queixas de saúde foi de 1,67 (IC95%: 1,09-2,56), e após o ajuste para os sintomas de TEPT reduziu para 1,57 (IC95%: 0,95-2,45); somado-se o ajuste para tabagismo, ingestão de álcool diária, legumes frescos e redução da escala SOC, houve diminuição da OR para 1.25 (IC95%: 0,76-2,04). Observou-se uma associação significativa entre as queixas de inatividade e de saúde física, mediadas pelos sintomas de TEPT.

El objetivo del estudio fue investigar la asociación entre inactividad física y molestias de salud en relación con síntomas de estrés postraumático (SEP), factores nutricionales y de comportamiento, así como el sentido de coherencia (SDC) entre las niñas de octavo grado. Una muestra aleatoria de las niñas (N = 862) fueron entrevistadas de forma anónima sobre las quejas de salud, el nivel de actividad física, los SEP, escala SOC de Antonovsky, conductas de salud, los hábitos alimentarios. Todas las quejas de salud se asociaron significativamente con la inactividad física. El odds ratio (OR) no ajustado de la inactividad física para las quejas de salud fue de 1,67 (IC95%: 1,09-2,56), después del ajuste para los SEP se redujo a 1,57 (IC95%: 0,95-2,45); tras los ajustes debidos al tabaco, bebidas alcohólicas diarias, verduras frescas, el SDC disminuyó a 1,25 (IC95%: 0,76-2,04). Se encontró una asociación significativa entre la inactividad y las quejas de salud fueron medidas por los SEP.

Inappropriate antibiotic prescribing and demand for antibiotics in patients with upper respiratory tract infections is hardly different in female versus male patients as seen in primary care.

BACKGROUND: Unnecessary prescribing of antibiotics is a major public health concern. General practitioners (GPs) prescribe most antibiotics, often for upper respiratory tract infections (URTIs), and have in general been shown to prescribe antibiotics more often to women. No studies have examined the influence of patient gender on unnecessary antibiotic prescribing. OBJECTIVES: To study a possible gender difference in unnecessary antibiotic prescriptions for URTIs in general practice; to assess whether a possible difference is explained by patient demand for antibiotics. METHODS: Post-hoc analysis of a cross-sectional study including 15,022 patients with URTI (acute rhinitis, acute otitis media, acute sinusitis, acute pharyngotonsillitis) from Argentina, Denmark, Lithuania, Russia, Spain and Sweden (HAPPY AUDIT Project). The association between gender and unnecessary antibiotic prescriptions, unadjusted and adjusted for treatment demand, was analysed using logistic regression models. RESULTS: A total of 25% of patients with URTI received antibiotics; in 45% of the cases, antibiotics were unnecessary. Overall, no gender difference for unnecessary prescribing of antibiotics for URTIs was found. Women with acute otitis media received an unnecessary antibiotic twice as often as men (14.4% versus 7.1%). In Danish patients with acute pharyngotonsillitis, there was a gender difference in unnecessary prescriptions for antibiotics (women 29.1% versus men 48.6%). Some 14% of patients receiving unnecessary antibiotics demonstrated a demand for antibiotics, but no gender difference was found in this group. CONCLUSION: This study indicated a high rate of unnecessary antibiotic prescribing for URTIs in general practice, but overall found no gender differences in receiving unnecessary antibiotic prescriptions.

Comparative analysis of endogenous plant pararetroviruses in cultivated and wild Dahlia spp.

Two distinct caulimoviruses, Dahlia mosaic virus (DMV) and Dahlia common mosaic virus, and an endogenous plant pararetroviral sequence (DvEPRS) were reported in Dahlia spp. DvEPRS, previously referred to as DMV-D10, was originally identified in the US from the cultivated Dahlia variabilis, and has also been found in New Zealand, Lithuania and Egypt, as well as in wild dahlia species growing in their natural habitats in Mexico. Sequence analysis of three new EPRSs from cultivated dahlias from Lithuania [D10-LT; 7,159 nucleotide level (nt)], New Zealand (D10-NZ, 7,156 nt), and the wild species, Dahlia rupicola, from Mexico (D10-DR, 7,133 nt) is reported in this study. The three EPRSs have the structure and organization typical of a caulimovirus species and showed identities among various open reading frames (ORFs) ranging between 71 and 97 % at the nt when compared to those or the known DvEPRS from the US. Examination of a dataset of seven full-length EPRSs obtained to date from cultivated and wild Dahlia spp. provided clues into genetic diversity of these EPRSs from diverse sources of dahlia. Phylogenetic analyses, mutation frequencies, potential recombination events, selection, and fitness were evaluated as evolutionary evidences for genetic variation. Assessment of all ORFs using phylogenomic and population genetics approaches suggests a wide genetic diversity of EPRSs occurring in dahlias. Phylogenetic analyses show that the EPRSs from various sources form one clade indicating a lack of clustering by geographical origin. Grouping of various EPRSs into two host taxa (cultivated vs. wild) shows little divergence with respect to their origin. Population genetic parameters demonstrate negative selection for all ORFs, with the reverse transcriptase region more variable than other ORFs. Recombination events were found which provide evolutionary evidence for genetic diversity among dahlia-associated EPRSs. This study contributes to an increased understanding of molecular population genetics and evolutionary pathways of these reverse transcribing viral elements.

An international serotype 3 clone causing pediatric noninvasive infections in Israel, Costa Rica, and Lithuania.

BACKGROUND: Serotype 3 is known for its ability to cause invasive diseases worldwide. In the United States, after introduction of the 7-valent pneumococcal conjugate vaccine (PCV7), the prevalence of a serotype 3 clone (Netherlands-31/ST180) increased. The present study was aimed to evaluate the importance of serotype 3 clones in noninvasive infections in Israel, Costa Rica, and Lithuania. METHODS: Molecular typing and antibiotic resistance were performed on 77 serotype 3 strains recovered from pediatric noninvasive infections during 2003-2005, and on 50 carried strains from healthy carriers. RESULTS: Serotype 3 ranked second among isolates from noninvasive infections in Costa Rica and Lithuania, and seventh among the Israeli isolates. Pulsed field gel electrophoresis (PFGE) analysis revealed the presence of 1 major cluster (64/77, 83%); this cluster comprised 60/64 fully susceptible strains that corresponded to the Netherlands-31/ST180 clone, and 4/64 multidrug-resistant strains, all from Lithuania, that corresponded to ST505, a double locus variant of ST180. Two additional fully susceptible clones, ST458 (11/77, 14%) and ST1116 (2/77, 3%), were found among the Israeli and Costa Rican strains, respectively. The same PFGE clusters identified among noninvasive infections were found among 50 isolates from carriers, with the same molecular characteristics. CONCLUSIONS: Serotype 3 accounts for a large proportion of mucosal disease in children, even before the introduction of PCV7. The data presented here describe for the first time the importance of a multidrug-resistant serotype 3 clone, ST505, in noninvasive infections.

Drug and alcohol services in middle-income countries.

PURPOSE OF REVIEW: The present review summarizes current research in middle-income countries on drug and alcohol services for prevention, screening, treatment, care and rehabilitation between June 2006 and December 2007. RECENT FINDINGS: There is a dearth of scientific literature on prevention, treatment and rehabilitation in middle-income countries and no novel effective approaches reported during the review period. The Lancet Series on Global Mental Health showed only 0.7% of all papers reviewed were on low-income and middle-income countries. Several studies in these countries confirmed the effectiveness of brief interventions in treating alcohol use disorders at a primary care level. One study on alcohol screening in Brazil produced a promising screening tool. Other studies reported the availability of pharmacological and nonpharmacological treatments for alcohol and drug use disorders. Overall, poor accessibility to services and delayed onset of treatment persist. Political and cultural environments play a crucial role in providing services to fulfill treatment needs. SUMMARY: During the review period, reports from middle-income countries on alcohol and drug services were very limited. A few studies in some countries confirm the effectiveness of brief interventions in primary care settings. There is an obvious need for more research on alcohol and drug treatment services in middle-income countries.

A cross-cultural investigation of the role of foot size in physical attractiveness.

Disparate cultural practices suggest that small foot size may contribute to female attractiveness. Two hypotheses potentially explain such a pattern. Sexual dimorphism in foot size may lead observers to view small feet as feminine and large feet as masculine. Alternately, because small female feet index both youth and nulliparity, evolution may have favored a male preference for this attribute in order to maximize returns on male reproductive investment. Whereas the observational hypothesis predicts symmetrical polarizing preferences, with small feet being preferred in women and large feet being preferred in men, the evolutionary hypothesis predicts asymmetrical preferences, with the average phenotype being preferred in men. Using line drawings that varied only in regard to relative foot size, we examined judgments of attractiveness in nine cultures. Small foot size was generally preferred for females, while average foot size was preferred for males. These results provide preliminary support for the hypothesis that humans possess an evolved preference for small feet in females.

Drug in four countries meet U.S. standards.

Antiretroviral drugs from four developing countries have been found to meet United States Pharmacopoeia standards for the active drug amount listed on the label, according to a study in the May 1 Clinical Infectious Diseases.