ABSTRACT
The potential benefits of adiponectin replacement therapy extend to numerous human diseases, with current research showing particular interest in its effectiveness against specific cancer forms, especially hormone-related. However, limitations in the pharmacological use of the intact protein have led to a focus on alternative options. AdipoRon is an extensively studied non-peptidic drug candidate for adiponectin replacement therapy. While researchers have explored the efficacy and therapeutic applications of AdipoRon in various disease conditions, their effects against cancer models advanced more, with no review regarding AdipoRon's efficacy against hormone-related cancers being published. The present systematic review aims to fill this gap. Preclinical evidence was compiled from PubMed, EMBASE, COCHRANE, and Google Scholar following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and the manuscript's quality assessment was conducted using the Joanna Briggs Institute (JBI) Checklist Critical Appraisal Tool for Systematic Reviews' Quality. The included nine studies incorporated various cell and animal models of the pancreas, gynaecological system, and osteosarcoma cancers. AdipoRon demonstrated effectiveness against pancreatic cancer by activating p44/42 MAPK, mitochondrial dysfunction, and AMPK-mediated inhibition of ACC1. In gynaecological cancers, it exhibited promising anticancer effects through the activation of AMPK, potential inhibition of mTOR, and modulation of the SET1B/BOD1/AdipoR1 signaling cascade. Against osteosarcoma, AdipoRon worked by perturbing ERK1/2 signaling and reducing p70S6K phosphorylation. AdipoRon shows promise in preclinical studies, but human trials are crucial for clinical safety and effectiveness. Caution is needed due to potential off-target effects, especially in cancer therapy with multi-target approaches. Structural biology and computational methods can help predict these effects.
Subject(s)
Adiponectin , Osteosarcoma , Piperidines , Animals , Humans , AMP-Activated Protein Kinases/metabolism , LogicABSTRACT
Resumo: O raciocínio e a emoção apresentam complexas e numerosas relações entre si, podendo prejudicar ou beneficiar o processamento lógico. Visando investigar a influência da tonalidade afetiva sobre o raciocínio, realizou-se uma revisão sistemática advinda da busca de estudos publicados nas bases de dados do Portal de Periódicos da Capes, Scielo, PubMed e Google Acadêmico. Os descritores utilizados foram: (affective content OR evaluative content OR emotion*) AND (reasoning). Após análise e submissão aos critérios de inclusão e exclusão, restaram 17 artigos, duas dissertações de mestrado e uma tese de doutorado. Apenas um dos estudos foi realizado no Brasil. Os participantes das pesquisas selecionadas tiveram pior desempenho nas tarefas de raciocínio formadas por conteúdos valorativos negativos. Entretanto, os conteúdos negativos influenciaram de forma positiva o raciocínio dedutivo quando se mostravam relevantes para a realização da tarefa. Assim, os estudos selecionados parecem apontar para a importância das emoções sobre o raciocínio humano.
Abstract: Reasoning and emotions have many complex relations which can hinder or benefit logical processing. Intending to investigate the influence of affective content on reasoning, we conducted a systematic review on scientific articles published on the Capes Journals Portal, Scielo, PubMed and Academic Google databases, retrieved using the descriptors (affective content OR evaluative content OR emotion*) AND (reasoning). After analysis and application of inclusion and exclusion criteria, 17 papers, two master's dissertations and one doctorate thesis remained. Only one study was conducted in Brazil. Research participants showed a worse performance in reasoning tasks composed by negative emotional content. However, negative emotional content influenced deductive reasoning positively when they proved to be relevant to the task. Hence, the reviewed studies suggest an importance of emotions for human reasoning.
Résumé : Le raisonnement et l'émotion entretiennent de nombreuses relations complexes qui peuvent entraver ou favoriser le procès logique. Dans le but d'étudier l'influence du contenu affectif sur le raisonnement, on a effectué une revue systématique des articles scientifiques publiés sur les base des données Portail des Périodiques du Capes, Scielo, PubMed et Google Académique, retrouvés en utilisant les descripteurs (affective content OR evaluative content OR emotion*) AND (reasoning). Après l'analyse et application des critères d'inclusion et d'exclusion, 17 articles, deux mémoires de maîtrise et une thèse de doctorat ont été retenus. Une seule étude a été menée au Brésil. Les participants aux recherches ont montré une pire perfomance dans les tâches de raisonnement composés d'un contenu affectif négatif. Cependant, ce contenu a influencé positivement le raisonnement déductif lorsqu'il s'est avéré pertinent pour la tâche. Les études examinées suggèrent donc que les émotions jouent un rôle important dans le raisonnement humain.
Resumen: El razonamiento y las emociones tienen relaciones complejas entre sí, que pueden perjudicar o ayudar el procesamiento lógico. Para investigar la influencia del tono afectivo sobre el razonamiento, se realizó una revisión sistemática a partir de la búsqueda de estudios publicados en las bases de datos del Portal de Periódicos Capes, SciELO, PubMed y Google Académico. Los descriptores utilizados fueron los siguientes: (affective content OR evaluative content OR emotion*) AND (reasoning). Después de la aplicación de los criterios de inclusión y exclusión, se seleccionaron 17 artículos, dos disertaciones de maestría y una tesis doctoral. Solo uno de los estudios se llevó a cabo en Brasil. Los participantes de las investigaciones seleccionadas tuvieron un peor desempeño en las tareas de razonamiento formadas por contenidos emocionales negativos. Estos influenciaron de forma positiva el razonamiento deductivo cuando eran relevantes para la realización de la tarea. Los estudios seleccionados parecen evidenciar la importancia de las emociones sobre el razonamiento humano.
Subject(s)
Humans , Male , Female , Emotions , Logic , Stress, PsychologicalABSTRACT
OBJECTIVES: The reduction in size of these systems, which increases their reliability, biocompatibility and robustness, is essential to the complete implantation of the VADs, which is the main focus of the current state of art. Continuous flow VADs are actuated by brushless motors due to their reliability. The objective of the current project was to implement and simulate sensorless speed control in order to actuate VAD. METHODS: In order to increase the robustness of the system even further, a strategy that does not use Hall sensors can be implemented. The sensorless strategy to control speed that was implemented in this work aims to detect the position of the rotor by using the coil of the inactive phase in order to sense the variation in magnetic flux, which comes in the form of back-electromotive forces. RESULTS: A three phase inverter to electrically commute the motor's phases, a conditioning circuit that obtains the back-electromotive forces and a speed controller were developed. The speed control and the commutation logic were implemented by using a microcontroller. The results that were obtained in computational simulations indicated that the three-phase inverter, the commutation logic and the controller reached the project requirements. The implemented microcontroller commutation logic presented the expected behavior. Commutation signals were obtained in six stages, necessary for the correct activation of the phases of the brushless motor. The controller was validated in terms of its step response, demonstrating low overshoot and fast control action in the system. CONCLUSIONS: To further enhance the robustness of the system, an alternative strategy that eliminates the use of Hall sensors can be employed. The sensorless speed control strategy, implemented in this study, detects the position of the rotor by measuring variations in magnetic flux through the coil of the inactive phase, thus relying on back-electromotive forces for detection.
Subject(s)
Computer Simulation , Heart-Assist Devices , S Phase Cell Cycle Checkpoints , LogicABSTRACT
In this article, I use a metaphorical concept in order to propose an interpretation for the dialogical relationship that occurs between I-positions in the human self. Metaphor is a useful tool for scientific production and its heuristic value has been demonstrated in several fields of knowledge. I claim a musico-logical metaphor to explain dynamic dialogic processes that occur when I-positions are in agreement or disagreement relationship. These dialogic processes are based on tension and release and, in a complementary way, can result in contradictory, tautological, or contingency relations between I-positions. These relations were categorized using concepts from Music and Logic, thus creating a theoretical model composed of metaphorical concepts. To provide evidence of how a musico-logical metaphor might contribute to the interpretation of relations between I-positions in the system of self, I discuss a case study of a rural worker and analyze how child labor marked his life trajectory throughout different moments. The musico-logical metaphor might contribute to dialogical processes understanding that occur at the border of the agreement-disagreement dyad in the system of the self, since this metaphor proposes to identify, from a cogenetic understanding, dialogic interactions between I-positions located in this border, thus transforming the agreement-disagreement dyad into a triadic agreement-border-non-agreement set.
Subject(s)
Logic , Metaphor , Child , Humans , Models, Theoretical , KnowledgeABSTRACT
RESUMO: A partir da constatação de contradições cotidianas e de sua recepção na lógica clássica, onde não são admitidas, este trabalho teórico interroga, junto a outros campos, fenômenos linguageiros considerados indesejáveis e, consequentemente, descartáveis em descrições e análises. A discussão reconhece na Lógica paraconsistente avanços importantes para a abordagem das contradições em sistemas lógicos. Na Clínica de Linguagem, tropeços e embaraços são tratados como dados de subjetividade relevantes para elaborações teórico-clínicas; ali encontramos contribuições para discutir a contradição na Psicanálise. Resta dizer que o interesse pela questão decorre da afirmação de Freud de que a vida psíquica é composta de contradições.
ABSTRACT: Based on the observation of everyday contradictions and their reception in classical logic, where they are not admitted, this theoretical work interrogates, together with other fields, linguistic phenomena considered undesirable and disposable in descriptions and analyses. The discussion recognizes in Paraconsistent Logic important advances for the approach of contradictions in logical systems. At the Language Clinic, stumbling blocks and embarrassments are treated as relevant subjectivity data for theoretical-clinical elaborations; there we find contributions to discuss the contradiction in Psychoanalysis. It remains to be said that the interest in the question stems from Freud's assertion that psychic life is made up of contradictions.
Subject(s)
Psychoanalysis , Unconsciousness , LogicABSTRACT
ABSTRACT Games and play are strategies to assist in the cognitive development of children. However, there are still gaps about their effects and associations when it comes to children's cognition. Thus, the objective is to synthesize the influence of active games and play on the cognition of children. The databases searched were: Lilacs, PsycINFO, Pubmed, Scielo and Scopus. Articles with observational or experimental design were included. Their quality was evaluated by means of RoB 2. Five studies were included, in accordance with the eligibility criteria. All studies had an experimental design, with two being conducted chronically, and three, acutely. Three studies showed positive effects of games and play on attention, reaction time, and executive functions: inhibitory control, logical reasoning, verbal factor, numerical factor, spatial factor, and general intelligence. Regarding the methodological quality of the studies, it is necessary to better describe and use the randomization allocation process, be more careful with data analysis, and avoid multiple assessments for a single variable. It is concluded that active games and play can generate a positive effect on the attention and executive functions of children. Further research is needed for an understanding of the relationship that parameters such as intensity, length and types of activities have with cognition.
RESUMO Jogos e brincadeiras são estratégias para auxiliar no desenvolvimento cognitivo do público infantil. Contudo ainda existem lacunas sobre os efeitos e associações dos jogos e brincadeiras ativos na cognição de crianças. Assim, o objetivo é sintetizar a influência dos jogos e brincadeiras ativos na cognição de crianças. As bases de dados foram: Lilacs, PsycINFO, Pubmed, Scielo e Scopus. Foram incluídos artigos com delineamento observacional ou experimental. A qualidade dos artigos foi avaliada com a RoB 2. Cinco estudos foram incluídos seguindo os critérios de elegibilidade. Todos os estudos apresentaram delineamento experimental, dois realizados de forma crônica e três de forma aguda. Três estudos apresentaram efeitos positivos dos jogos e brincadeiras na atenção, tempo de reação e funções executivas: controle inibitório, raciocínio lógico, fator verbal, fator numérico, fator espacial e inteligência geral. Quanto à qualidade metodológica dos estudos é necessário melhor descrição e utilização do processo de alocação da randomização, maior cuidado na análise de dados e evitar múltiplas avaliações para uma variável. Conclui-se que jogos e brincadeiras ativos podem gerar efeito positivo para a atenção e funções executivas de crianças. Mais estudos são necessários para compreensão da relação de parâmetros como intensidade, duração e tipos de atividades com a cognição.
Subject(s)
Cognition , Play and Playthings/psychology , Attention , Child , Systematic Reviews as Topic , Intelligence , Logic , MemoryABSTRACT
OBJECTIVE: To present a reflection on the importance of logical thinking for clinical nursing care. METHOD: Reflection paper. REFLECTION: The exercise of an effective clinical care brings with it the need for logical thinking and adequate reasoning for safe and effective nursing practices. Therefore, training based on philosophical principles that encourage the increase of logical and critical thinking is considered unquestionable, ensuring professionals the systematization of assistance with the application of the nursing process based on scientific understanding and strong arguments supported by the path of truthfulness, morality, ethics and critical self-reflection in order to value clinical practices. FINAL CONSIDERATIONS: The importance of logical thinking for nursing care is ratified here, supporting nursing care systematization and the nursing process stages. Thus, nurses can use clinical reasoning skills to deliver a humane, ethical, and effective professional performance.
Subject(s)
Nursing Process , Thinking , Clinical Competence , Humans , Logic , Problem SolvingABSTRACT
The aim of the present study was to analyze the incidence of fracture of ProDesign Logic system instruments in endodontic treatments performed by a specialist, in addition to identifying the dental group, arch, and the root canal thirds in which the fractures occurred more frequently. Digital radiographs and medical records were initially analyzed and resulted in the selection of 561 teeth (1302 canals) treated between 2018 and 2020, using the ProDesign Logic system instruments. These data were reassessed to determine the occurrence of fractures and identify the dental group and root canal thirds in which they occurred. Then, the data were statistically analyzed using the Fisher's Exact Test (p < 0.05). The general fracture rates were 8.5 and 3.69%, considering the number of teeth and canals treated, respectively. Mandibular first molars were the teeth most associated with the occurrence of fractures (19.1%). When the arches were compared, there was no statistical difference regarding the number of fractures in the different root canal thirds (p = 0.307). However, they were more frequent in the apical third in both arches (p = 0.000). The incidence of fracture of ProDesign Logic system instruments was relatively high and occurred more frequently in the apical third of molars.
Subject(s)
Logic , Root Canal Preparation , Cross-Sectional Studies , Equipment Design , Incidence , Retrospective StudiesABSTRACT
The application of automation techniques to water pump systems, combined with modern control techniques, has been increasing the hydraulic and energy efficiency of such systems. In this context, the objective of this work is to present an intelligent method of flow control based on Brain Emotional Learning Basic Intelligent Control (BELBIC), which will be applied to an experimental workbench of a pumping system, located in the Energy Efficiency and Energy Quality Laboratory (LEEQE) at Federal University of Pernambuco (UFPE). The parameters of this controller are optimized with a particle swarm optimization (PSO) technique with minimization of Integral Absolute Error (IAE). Initial tests were performed in a computational environment so that the system's performance could be pre-tested, thereby the dynamics of the system was modeled from real data generated in the process. The experimental results were obtained through the implementation of this control system in a programmable logic controller (PLC), which was the device responsible for all the automation of the workbench previously mentioned. The data of this workbench were collected using a supervisory system exclusively developed for this work. These data were then used to analyze the performance of the proposed control system, which demonstrated that its behavior was efficient.
Subject(s)
Algorithms , Industry , Automation , Logic , Physical PhenomenaABSTRACT
In recent decades, precariousness has become an increasingly prominent feature of life in many countries. At the same time as precarious forms of social relations have proliferated, self-help books have become tremendously popular. This article examines five best-selling self-help books in Mexico - two promoting mental wellness, one providing financial advice, one about romantic relationships, and one sharing inspirational lessons regarding success - to explore how self-help texts reflect the cultural logic of precariousness. While encouraging readers to overcome challenges, think positively, and transform bad habits into good ones, the texts present visions of human agency free from social constraint. Self-help books in Mexico reproduce a cultural logic that corresponds to material realities of precariousness in work and family life. This logic helps account for the expanding popularity of the genre and encourages a marginalization of the sociological imagination in popular culture - a marginalization that sociologists should contest through greater public engagement.
Au cours des dernières décennies, la précarité est devenue une caractéristique de plus en plus importante de la vie dans de nombreux pays. Parallèlement à la prolifération des formes précaires de relations sociales, les livres d'auto-assistance sont devenus extrêmement populaires. Cet article examine cinq livres d'auto-assistance les plus vendus au Mexique - deux promouvant le bien-être mental, un fournissant des conseils financiers, un sur les relations amoureuses, et un partageant des leçons inspirantes sur le succès - pour explorer comment les textes d'auto-assistance reflètent la logique culturelle de la précarité. Tout en encourageant les lecteurs à surmonter les difficultés, à penser de manière positive et à transformer les mauvaises habitudes en bonnes habitudes, les textes présentent des visions de l'agence humaine libérée des contraintes sociales. Les livres d'auto-assistance au Mexique reproduisent une logique culturelle qui correspond aux réalités matérielles de la précarité dans la vie professionnelle et familiale. Cette logique contribue à expliquer la popularité croissante du genre et encourage la marginalisation de l'imaginaire sociologique dans la culture populaire - une marginalisation que les sociologues devraient contester en s'engageant davantage auprès du public.
Subject(s)
Books , Sociology , Humans , Imagination , Logic , MexicoABSTRACT
When people seek to understand concepts from an incomplete set of examples and counterexamples, there is usually an exponentially large number of classification rules that can correctly classify the observed data, depending on which features of the examples are used to construct these rules. A mechanistic approximation of human concept-learning should help to explain how humans prefer some rules over others when there are many that can be used to correctly classify the observed data. Here, we exploit the tools of propositional logic to develop an experimental framework that controls the minimal rules that are simultaneously consistent with the presented examples. For example, our framework allows us to present participants with concepts consistent with a disjunction and also with a conjunction, depending on which features are used to build the rule. Similarly, it allows us to present concepts that are simultaneously consistent with two or more rules of different complexity and using different features. Importantly, our framework fully controls which minimal rules compete to explain the examples and is able to recover the features used by the participant to build the classification rule, without relying on supplementary attention-tracking mechanisms (e.g. eye-tracking). We exploit our framework in an experiment with a sequence of such competitive trials, illustrating the emergence of various transfer effects that bias participants' prior attention to specific sets of features during learning.
Subject(s)
Concept Formation , Logic , Bias , Humans , LearningABSTRACT
A major hypothesis about conditionals is the Equation in which the probability of a conditional equals the corresponding conditional probability: p(if A then C) = p(C|A). Probabilistic theories often treat it as axiomatic, whereas it follows from the meanings of conditionals in the theory of mental models. In this theory, intuitive models (system 1) do not represent what is false, and so produce errors in estimates of p(if A then C), yielding instead p(A & C). Deliberative models (system 2) are normative, and yield the proportion of cases of A in which C holds, i.e., the Equation. Intuitive estimates of the probability of a conditional about unique events: If covid-19 disappears in the USA, then Biden will run for a second term, together with those of each of its clauses, are liable to yield joint probability distributions that sum to over 100%. The error, which is inconsistent with the probability calculus, is massive when participants estimate the joint probabilities of conditionals with each of the different possibilities to which they refer. This result and others under review corroborate the model theory.
Subject(s)
COVID-19 , Judgment , Humans , Logic , Models, Psychological , Probability , Problem Solving , SARS-CoV-2ABSTRACT
This work details a methodology of design and test of a new prototype emergency mechanical ventilator called Fenix for the COVID-19 crisis in Peru. This equipment was manufactured with industrial equipment for the embedded and pneumatic systems, such as a Programmable Logic Controller (PLC), proportional flow valves, sensors, uninterruptible power supply (UPS), industrial panel HMI 15" and other electrical and pneumatic parts from Festo and Schneider Electric. This selection was in accordance with safety requirements based on ISO 80601-2-12: 2020-02. This study included two ventilatory modes, pressure- controlled in continuous mandatory ventilation (PC-CMV) and volume-controlled in continuous mandatory ventilation (VC-CMV), these control algorithms were evaluated analytically and experimentally in a FLUKE VT-650 Gas Flow Analyzer and an Acculung Fluke connected with a computer for comparing 9 ventilatory parameters in 4 different states as µ, simulation of the variation of the pressure control in a patient, and Ï´, simulation of alveolar recruitment in an intensive care patient, both states to PC-CMV, and also ß, simulation of the variation of the flow control in a patient, and α, simulation of alveolar recruitment in an intensive care patient, both last states to VC-CMV. Additionally, we study the pressure, volume, and flow graphs in the Fenix user interface for comparison with data recovered from Fluke Medical VT650 Gas Flow Analyzer. The results demonstrate an error in the flow measurement for the 4 states due to the peaks that are not detected by the low-pass filter of the sensor, however, a similar trend is seen in the control ventilatory graphs of the calibrator. Finally, the ventilator prototype provides ventilatory support, with a maximum tidal volume error of 12.93 % and inspiratory pressure of -20.15 % with respect to the set value; and it allows to monitor the main ventilation parameters with a calculation error between -6 to 25 %.Clinical Relevance - Established the design of emergency mechanical ventilator using PLC and industrial components.
Subject(s)
COVID-19 , Humans , Logic , Peru , SARS-CoV-2 , Ventilators, MechanicalABSTRACT
El artículo aporta respuestas a la pregunta ¿Cuál es la potencia explicativa de la teoría de las RS? Se enumeran diversas aplicaciones de las RS como constructos de significación colectiva del sentido común de las personas. Se apela a las problemáticas clásicas abordadas y los distintos campos disciplinares que abarcan. La potencia explicativa de las RS se analiza en términos de las diferentes lógicas de la explicación que implican las escuelas psicológicas y sociales que se compatibilizan con las RS. Se analiza el método comparativo como lógica explicativa y técnica que potencia las explicaciones para fenómenos que asocian RS y diversas teorías. La posmodernidad presenta innumerables desafíos a las ciencias humanas. Las RS pueden contribuir para varios de ellos demostrando ser una técnica poderosa. La actualidad de las RS consiste en develar los sentidos implicados en el sentido común contribuyendo a la comprensión del mundo actual y su gobernanza AU
The article provides answers to the question: What is the explanatory power of the SR theory? Various applications of SR are listed as constructs of collective meaning of people's common sense. It appeals to the classic problems addressed and the different disciplinary fields they cover.The explanatory power of the SR is analyzed in terms of the different logics of the explanation implied by the psychological and social schools that are compatible with the SR.The comparative method is analyzed as an explanatory and technical logic that enhances explanations for phenomena that associate SR and various theories.Postmodernity presents myriad challenges to the human sciences. RS can contribute to several of them proving to be a powerful technique. SR today consists of unveiling the meanings involved in common sense, contributing to the understanding of the current world and its governance AU
Subject(s)
Perception , Knowledge , Comprehension , Theory of Mind , Logic , MethodsABSTRACT
Este artículo tuvo como objetivo comprender la integración de la filosofía de Charles Peirce en la Ciencia de la Información. Desde el punto de vista metodológico, se trata de una investigación cualitativa y cuantitativa con el uso de técnicas bibliométricas. Los datos bibliográficos se recopilaron de cuatro bases de datos, dos específicas de Ciencias de la Información: Bibliotecas y Resúmenes de Ciencias de la Información de ProQuest - LISA y la base de datos de referencia de artículos de revistas en Ciencias de la Información; y dos multidisciplinarias: Scopus y Web of Science. Los resultados muestran que la filosofía Peirceana se está consolidando como una contribución teórica importante en las investigaciones y publicaciones de Ciencias de la Información, considerando el número relativamente significativo (114) de publicaciones recuperadas de las bases de datos antes mencionadas. Estos trabajos abordan el pragmatismo en estudios sobre gestión del conocimiento, sistemas de información, filosofía de la información, así como en la organización del conocimiento, especialmente relacionados con la comprensión o el proceso inferencial de indexación en sistemas de información. El artículo concluye que existe un interés creciente entre la comunidad científica de las Ciencias de la Información por desarrollar la filosofía de Peirce de una manera holística, no limitada al primer nivel de la semiótica peirceana, la gramática especulativa, ya que también incluye estudios que profundizan en la inferencia, proceso vinculado a la Lógica Pura(AU)
The purpose of the study was to understand the integration of Charles Peirce's philosophy into information science. From a methodological point of view, it is a qualitative and quantitative study based on bibliometric techniques. The bibliographic data were obtained from four databases, two specifically related to information sciences: ProQuest - LISA Information Sciences Libraries and Abstracts, and the reference database for articles from information sciences journals; and two multidisciplinary databases: Scopus and Web of Science. Results show that Peircean philosophy is gradually consolidating as an important theoretical contribution in information sciences studies and publications, considering the relatively significant number (114) of publications retrieved from the aforementioned databases. These studies address pragmatism in research about knowledge management, information systems, information philosophy and knowledge organization, particularly as related to understanding or the inferential indexing process in information systems. The article concludes that there is a growing interest by the information sciences scientific community to develop Peirce's philosophy in a holistic manner, not limited to the first level of Peircean semiotics and speculative grammar, for it also includes studies dealing with inference, a process related to pure logic(AU)
Subject(s)
Humans , Philosophy , Bibliometrics , Information Science , LogicABSTRACT
Dual-chamber pacemaker is a fully automatic pacemaker with the function of simulating human physiological pacing. It regulates pacing by programming different refractory periods and various special functions, which are closely related to arrhythmia. After in-depth understanding of these special functions, regular electrocardiogram follow-up analysis is required to provide individualized optimal program control and so is appropriate the administration of the pacemaker's special functions to better provide optimal clinical guidance for patients with arrhythmia.
Subject(s)
Pacemaker, Artificial , Arrhythmias, Cardiac/etiology , Arrhythmias, Cardiac/therapy , Electrocardiography , Humans , Logic , Pacemaker, Artificial/adverse effectsABSTRACT
This paper presents a computational method based on non-classical logic dedicated to routing management and information stream control in communication networks. Paraconsistent logic (PL) was used to create an algorithmic structure whose main property is to accept contradiction. Moreover, a computational structure, the denominated paraconsistent data analyzer (PDAPAL2v), was constructed to perform routing management in communication networks. Direct comparisons of PDAPAL2v with a classical logic system that simulates routing conditions were made in the laboratory. In the conventional system, the paraconsistent algorithms were considered as binary logic gates, and in the tests, the same adjustment limits of PDAPAL2v were applied. Using a database with controlled insertion of noise, we obtained an efficacy of 97% in the detection of deteriorated packets with PDAPAL2v and 72% with the conventional simulation system. Functional tests were carried out, showing that PDAPAL2v is able to assess the conditions and degradation of links and perform the analysis and correlation of various inputs and variables, even if the signals have contradictory values. From practical tests in the laboratory, the proposed method represents a new way of managing and controlling communication network routes with good performance.
Subject(s)
Algorithms , Computer Communication Networks , Communication , Computer Simulation , LogicABSTRACT
Abstract. Objective. This study characterized the electroencephalographic correlation (rEEG) between prefrontal and parietalcortices in young men while solving logical-mathematical problems after 18 sessions of cognitive training. Method. Two training groups were formed: one trained with gradually increased complexity (CT), the other with no increase in complexity (ST). Results. CT had a greater number of correct responses in the post-training evaluation than ST and showed a higher correlation between the left frontopolar-parietal cortices in almost all EEG bands, and between the dorsolateral-parietal cortices in the alpha1 band while solving math problems post-training. Results suggest that major functional synchronization between the left prefrontal and parietal cortices plays an important role in improving mathematical problem-solving after cognitive training.
Resumen Objetivo. El presente estudio caracteriza la correlación electroencefalográfica (rEEG) entre las cortezas prefrontal y parietal en hombres jóvenes durante la resolución de problemas lógico-matemáticos después de 18 sesiones de entrenamiento cognitivo. Método. Se formaron dos grupos de entrenamiento: uno entrenado con un incremento gradual de complejidad (CT) y el otro sin incremento de complejidad (ST). Resultados. El grupo CT presentó un mayor número de respuestas correctas que el grupo ST en la evaluación post entrenamiento, a su vez mostró un incremento en la correlación entre las cortezas frontopolar y parietal izquierdas en la mayoría de las bandas, así como entre las cortezas dorsolateral y parietal en la banda alfa1 durante la resolución de problemas posterior al entrenamiento. Los resultados sugieren que el incremento en la sincronización funcional entre las cortezas prefrontal y parietal izquierdas juega un rol importante en la resolución de problemas matemáticos después del entrenamiento cognitivo.
Subject(s)
Humans , Male , Adult , Electroencephalography , Cognitive Training , Logic , Mathematics , MexicoABSTRACT
Abstract Dual-chamber pacemaker is a fully automatic pacemaker with the function of simulating human physiological pacing. It regulates pacing by programming different refractory periods and various special functions, which are closely related to arrhythmia. After in-depth understanding of these special functions, regular electrocardiogram follow-up analysis is required to provide individualized optimal program control and so is appropriate the administration of the pacemaker's special functions to better provide optimal clinical guidance for patients with arrhythmia.
Subject(s)
Pacemaker, Artificial/adverse effects , Arrhythmias, Cardiac/etiology , Arrhythmias, Cardiac/therapy , Electrocardiography , LogicABSTRACT
Nos proponemos un recorrido por los escritos de Freud, que apunte a cernir los lazos entre creatividad y psicoanálisis, junto con los aportes de M. Klein y J. Lacan, con el propósito de dilucidar el novedoso aporte de D. Winnicott, acerca de una creación primaria, anterior a la sublimación, fundante de la zona propicia para la apertura de lo posible a ser subjetivado
We propose a journey through the writings of Freud, which aims to close the ties between creativity and psychoanalysis, together with the contributions of M. Klein and J. Lacan, in order to elucidate the novel contribution of D. Winnicott, about a primary creation, prior to sublimation, founding of the area conducive to the opening of the possible to be subjectivated