ABSTRACT
A arteriosclerose de Monckeberg pode ser uma causa rara de isquemia grave dos membros inferiores. Relatamos o caso de um paciente com isquemia crítica do membro inferior, sem condições de revascularização, que evoluiu para amputação. O paciente não apresentava os fatores de risco clássicos para aterosclerose. O diagnóstico anatomopatológico foi de arteriosclerose por calcificação da média de Monckeberg.
Subject(s)
Humans , Male , Middle Aged , Monckeberg Medial Calcific Sclerosis/surgery , Monckeberg Medial Calcific Sclerosis/complications , Ischemia/complications , Ischemia/diagnosis , Lower Extremity/injuriesABSTRACT
BACKGROUND: Since its first description, Mönckeberg's sclerosis has only been related to arterial media calcification, being listed among the primary diseases of the vessels. CASE PRESENTATION: We report here a clinically and histologically confirmed case of Mönckeberg's sclerosis in which the patient presented with massive areas of soft tissue calcifications in the pharynx and larynx. Polysomnographic parameters showed severe obstructive apnea refractory to nasal continuous positive airway pressure. Clinical and laboratory findings excluded concomitant endocrine or rheumatological diseases. CONCLUSION: Our data provide a new insight about Mönckeberg's sclerosis, i.e., the fact that the etiopathogenic process involved in the phenomenon of calcification may not be restricted only to the arteries, but may occur in the entire organism. Further studies of the etiopathogenesis of this disease are needed.