SEOM Guidelines 2015: a new era in the collaboration with the Spanish Cancer Research Cooperative Groups

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Neuroma of the radial digital nerve of the middle finger following trigger release.

Trigger digit release is a common surgical procedure with a low complication rate. One of the potential complications is digital nerve injury. Though uncommon, digital nerve injury can be significantly symptomatic to the patient. We report a case of radial digital nerve neuroma formation following trigger release of the middle finger, which is considered to be safe, in terms of risk of digital nerve injury. We discuss our management of the complication, possible pitfalls which may have resulted in the complication in our case and offer possible means of overcoming these pitfalls.

Treatment by collagen conduit of painful post-traumatic neuromas of the sensitive digital nerve: a retrospective study of 10 cases.

OBJECTIVES: The purpose of this retrospective study was to report the results of surgery in painful post-traumatic neuromas of the digital nerves treated by collagen conduits after excision of the neuromas, when two stumps were available. METHODS: We retrospectively reviewed all patients operated on for painful neuroma in our institution and having undergone repair with collagen conduits. Their files were retrieved by a coding file (CCAM version 10). Ten patients involving nine digital nerves and one common digital nerve were included. Primary outcome data points were static two-point discrimination, Semmes-Weinstein monofilament testing, Quick-Dash outcome survey scores, Cold Intolerance Symptom Severity (CISS) score and recurrence of pain at final follow-up. We set up a minimum follow-up period of 6 months after surgery. RESULTS: The patients' average age was 30 years. The average follow-up duration was 11.8 months. Five patients had excellent or good results (50%) at static two-point discrimination testing. Semmes-Weinstein monofilament testing results were full, diminished light touch or diminished protective sensation in nine digits (80%). The average Quick-Dash survey score was 19.3. The average CISS score was 27.8. There was no recurrence of pain. CONCLUSIONS: Our findings indicate that collagen conduit is an effective treatment for post-traumatic painful neuromas of digital nerves and common digital nerves.

Traumatic neuroma of the lower lip / Neuroma traumático del labio inferior

Traumatic neuroma is a rare disorder that represents a reactive proliferation of neural tissue following damage to an adjacent nerve. Clinically, oral lesions usually appear as a nodule of normal or grayish white smooth surface colouration, and patients may complain of pain as a frequent symptom. We report a case of a painless lower lip traumatic neuroma, clinically misdiagnosed as lipoma, in a 24-year old Caucasian woman. On intraoral examination, a yellowish and smooth sessile, well-delimited, painless, nodular lesion measuring 10 mm x 7 mm x 4 mm in size was observed on the mucosal lower lip. An excisional biopsy was performed and the final diagnosis was traumatic neuroma. After 18 months of follow-up, the patient is asymptomatic and there are no signs of recurrence.

El neuroma traumático es un trastorno raro que consiste en una proliferación reactiva del tejido neural tras producirse un daño en un nervio adyacente. Clínicamente, las lesiones orales normalmente aparecen como un nódulo de coloración normal o blanca grisácea, de superficie lisa, y los pacientes pueden quejarse de dolor como síntoma frecuente. Reportamos el caso de un neuroma traumático del labio inferior labio sin dolor, clínicamente mal diagnosticado como lipoma, en una mujer blanca de 24 años. En el examen intraoral, se observó una lesión nodular amarillenta, sésil, lisa, bien delimitada, e indolora, que medía 10 mm x 7 mm x 4 mm de tamaño, en la mucosa del labio inferior. Se realizó una biopsia, y el diagnóstico final fue un neuroma traumático. Después de 18 meses de seguimiento, el paciente se halla asintomático y no hay ninguna señal de recurrencia.

Marjolin's ulcer--a diagnostic dilemma.

Marjolin's ulcer is malignant change in a long-standing ulcer and or scar tissue. Commonly these lesions are treated as chronic ulcers and suspicion of malignancy should be raised with crusting, increase in pain or size of the ulcer and bleeding. We report a case of Marjolin's ulcer arising in a post-traumatic chronic ulcer of sole in a 60-year-old female.

Traumatic neuroma of the lower lip.

Traumatic neuroma is a rare disorder that represents a reactive proliferation of neural tissue following damage to an adjacent nerve. Clinically, oral lesions usually appear as a nodule of normal or grayish white smooth surface colouration, and patients may complain of pain as a frequent symptom. We report a case of a painless lower lip traumatic neuroma, clinically misdiagnosed as lipoma, in a 24-year-old Caucasian woman. On intraoral examination, a yellowish and smooth sessile, well-delimited, painless, nodular lesion measuring 10 mm x 7 mm x 4 mm in size was observed on the mucosal lower lip. An excisional biopsy was performed and the final diagnosis was traumatic neuroma. After 18 months of follow-up, the patient is asymptomatic and there are no signs of recurrence.

Embryonal rhabdomyosarcoma secondary to an open fracture of the tibia: a case report and review of literature.

Embryonal rhabdomyosarcoma (ERMS) is a highly malignant tumor in children and adolescents. It rarely occurs in adults. A 47-year-old patient presented with ERMS of the muscle flap transplant 20 years after an open type III-comminuted fracture of the lower leg. The affected leg was amputated. The patient refused adjuvant chemotherapy and one year after surgery remains disease-free and in good general condition.

Traumatic neuroma around the celiac trunk after gastrectomy mimicking a nodal metastasis: a case report.

Traumatic neuroma is a well-known disorder that occurs after trauma or surgery involving the peripheral nerve and develops from a nonneoplastic proliferation of the proximal end of a severed, partially transected, or injured nerve. We present a case of traumatic neuroma around the celiac trunk after gastrectomy in a 56-year-old man, which was confirmed by pathology. CT demonstrated the presence of a lobulated, homogeneous, hypoattenuating mass around the celiac trunk, mimicking a nodal metastasis.

Traumatic Neuroma around the Celiac Trunk after Gastrectomy Mimicking a Nodal Metastasis: A Case Report

Traumatic neuroma is a well-known disorder that occurs after trauma or surgery involving the peripheral nerve and develops from a nonneoplastic proliferation of the proximal end of a severed, partially transected, or injured nerve. We present a case of traumatic neuroma around the celiac trunk after gastrectomy in a 56-year-old man, which was confirmed by pathology. CT demonstrated the presence of a lobulated, homogeneous, hypoattenuating mass around the celiac trunk, mimicking a nodal metastasis.

Management of neuromas.

After nerve injury and regeneration, significant pain may be associated with the scar and altered sensation observed within the distribution of the injured nerve. A bulbous swelling may form at the severed nerve end, constituting a traumatic neuroma. The development of a painful neuroma may be more disabling to the patient than an area of anesthesia or even loss of motor function. Effective treatment of the painful neuroma remains a difficult problem. Diminished productivity, alterations in patient lifestyle, and possible progression to chronic pain syndromes must be considered within the scope of neuroma management, and treatment must focus on alleviating the pain and restoring the functional loss caused by the nerve injury. Careful patient selection is the cornerstone of successful outcomes. Once the patient has been selected, the surgical management of the painful neuroma throughout the body is based on basic principles that vary only slightly from region to region. Using these tenets, a neuroma management algorithm has been developed based on the pathophysio-logy of the neuroma, the results of experimental studies, review of patient outcomes, and understanding the psychology of pain in the surgical patient.

Skeletal muscle metastases at sites of documented trauma.

OBJECTIVE: Hematogenous metastases to skeletal muscles have been reported to be rare. We report eight biopsy-proven cases of skeletal metastases occurring in sites of previously documented skeletal muscle trauma. We retrospectively reviewed MR imaging examinations obtained at a large orthopedic surgical oncology service from January 1994 through December 2000 for biopsy-proven metastases to skeletal muscles. Our retrospective review revealed 28 patients with biopsy-proven skeletal muscle metastases. Of these 28 patients, eight had a documented clinical history of previous trauma at the site of skeletal metastasis. Five of these eight patients underwent MR imaging before the development of a metastasis. MR imaging revealed a hematoma in three of the five patients and a partial muscle tear in two of the five patients. The hematomas and partial muscle tears were in the same skeletal muscle location in which the metastatic disease subsequently developed. Metastatic disease was documented by MR imaging and subsequent biopsy. CONCLUSION: Skeletal muscle injury may alter muscle physiology and result in increased susceptibility to the development of metastatic disease at such sites.

Acute squamous cell carcinoma arising within a recent burn scar in a 14-year-old boy.

We have described the case of a 14-year-old boy who developed an acute squamous cell carcinoma within a healed burn scar 6 weeks after thermal injury. This is a rare condition necessitating early excision and histopathologic confirmation of clearance. The authors recommend early skin grafting of deep partial- and full-thickness burns to prevent future malignant transformation and a low index of suspicion of any nodules or ulceration appearing within a healed burn.

Tumores malignos no pós-transplante renal / Malignant neoplasias in post renal transplant

Analisamos 105 neoplasias malignas em 94 pacientes (6,2 porcento) - 11 deles com 2 tipos diferentes de neoplasias - observados em um grupo de 1.511 pacientes transplantados renais, entrre janeiro de 1965 a dezembro de 1990. Dos 105 casos de neoplasias malignas observadas 85 casos eram da linhagem epitelial e 20 casos de linhagem mesenquimal. Das neoplasias da linhagem epitelial, 33 casos (31.41 porcento) eram de pele - 19 casos espinocelulares, (CEC) 12 casos basocelulares (CBC) e 2 casos espino-basocelulares - , 14 casos (13,3 porcento) eram de língua, lábio ou períneo e 38 casos (36,2 porcento) eram de outros tipos: Fígado (8), intestino (5), rim primitivo (5), tireóide(3), colo uterino(5),endométrtio(3), melanoma(3), mama(2), pulmäo(2) e indiferenciados(2). Das neoplasias de linhagem mesenquimal, a mais frequente foi o sarcoma de Kaposi (9 casos), seguido de linfoma (4), leucemis(3) e outros tipos(4). A incidência de neoplasia aumentou com o tempo pós-transplante: de 0 a 12 meses, 1,05 porcento; de 13 a 60 meses, 2,83 porcento; de 61 a 120 meses,3,91 porcento; de 121 a 180 meses, 6,64 porcento; e de 181 a 240 meses, 7,46 porcento. Quanto à tipagem HLA,A,B, a incidencia de CEC e CBC foi mais frequente em portadores de antígenos A3, B7 e B27. Nenhum caso desse tipo de tumor ocorreu em pacientes HLA B17 e B35 positivos. Portadores de antígenos A3, B7 e B17 estiveram associados a presença de outras neoplasias epiteliais. Os portadores de neoplasia da linhagem mesenquimal tinham mais frequentemente antígenos A9, A28 e B12. O prognóstico foi pior nos casos das neoplasias de linhagem mesenquimal, onde a mortalidade foi de 60 porcento. Concluímos que as neoplasias malignas säo um tipo de complicaçäo importante no pós-transplante renal, sendo as mais frequentes aquelas da linhagem epitelial (81 porcento).(au)

Aneurysms of the superficial temporal artery: literature review and case reports.

Superficial temporal artery (STA) aneurysms are a medical rarity. There are less than 200 patients reported in the literature. The majority of cases are of traumatic etiology and occur in young men. The senior authors reported a case of STA aneurysm in 1978. We now review the literature and report on three additional patients with STA aneurysm and a fourth patient with a temporal lipoma that was diagnosed initially as an aneurysm. This is the first report of a preoperative diagnosis of STA aneurysm that subsequently proved incorrect.