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1.
JAMA Psychiatry ; 78(8): 896-902, 2021 08 01.
Article in English | MEDLINE | ID: mdl-33950163

ABSTRACT

Importance: Racial/ethnic and sex disparities in suicide ideation and attempts are well established, with higher risk of suicide ideation and attempt among US racial/ethnic minority school-aged youths (than their White peers) and girls and women (than boys and men). The suicide-related risk of racial/ethnic minority young adults, especially young women, may be strongly influenced by adverse childhood experiences, known early determinants of suicide ideation and attempts. Objectives: To assess lifetime and past-year prevalence estimates of suicide ideation and suicide attempt and to examine sex differences in the role of adverse childhood experiences as a prospective risk factor for Puerto Rican young adults from 2 sociocultural contexts. Design, Setting, and Participants: Data in this longitudinal cohort study are from 4 waves of the Boricua Youth Study, a population-based cohort study of Puerto Rican children from San Juan and Caguas, Puerto Rico, and the South Bronx, New York, 5 to 17 years of age (N = 2491; waves 1-3: 2000-2004) and 15 to 29 years of age (wave 4: 2013-2017). Data analysis was performed from February 26, 2019, to October 16, 2020. Exposures: Adverse childhood experiences were assessed by interview in childhood and early adolescence (waves 1-3) and included child maltreatment (physical, sexual, and emotional abuse and neglect), exposure to violence, parental loss (separation, divorce, and death), and parental maladjustment (mental health problems, substance or alcohol abuse, intimate partner violence, and incarceration). Main Outcomes and Measures: Lifetime and past-year suicide ideation and attempt were assessed in young adulthood (wave 4) using the World Health Organization Composite International Diagnostic Interview. Results: Among 2004 Puerto Rican young adults (80.4% of the original cohort; mean [SD] age, 22.9 [2.8] years; 1019 [50.8%] male), young women compared with young men had a higher prevalence of lifetime suicide attempt (9.5% vs 3.6%) and lifetime suicide ideation (16.4% vs 11.5%), whereas past-year suicide ideation (4.4% vs 2.4%) was not statistically different. Logistic regression models, adjusting for demographics and lifetime psychiatric disorders, found that young women but not young men with more adverse childhood experiences had higher odds of suicide ideation (lifetime; odds ratio [OR], 2.44; 95% CI, 1.54-3.87; past year: OR, 2.56; 95% CI, 1.18-5.55). More adverse childhood experiences were also prospectively associated with lifetime suicide attempt (OR, 1.16; 95% CI, 1.04-1.29), irrespective of sex. Conclusions and Relevance: The findings of this cohort study suggest that, among Puerto Rican young adults from 2 different sociocultural contexts, adverse childhood experiences were relevant to understanding suicide attempt and suicide ideation, the latter specifically among young women. The prevention of cumulative adverse childhood experiences could reduce later risk of suicide attempts and, among young women, for suicide ideation.


Subject(s)
Adverse Childhood Experiences/ethnology , Suicidal Ideation , Suicide, Attempted/ethnology , Adolescent , Adult , Female , Humans , Longitudinal Studies , Male , New York City/ethnology , Prevalence , Puerto Rico/ethnology , Sex Factors , Young Adult
2.
Infancy ; 25(5): 535-551, 2020 09.
Article in English | MEDLINE | ID: mdl-32857437

ABSTRACT

Play offers rich opportunities for toddlers to develop motor, social, cognitive, and language skills, particularly during interactions with adult caregivers who may scaffold toddlers to higher levels of play than toddlers achieve on their own. However, research on play has narrowly focused on children from White, middle-income backgrounds, leaving a dearth of knowledge about dyadic play in diverse cultural communities. We videorecorded 222 Mexican-American mothers playing with their 2-year-old toddlers with a standard set of toys. Play behaviors were coded as nonsymbolic or symbolic (play type) and as expressed through manual, verbal, or multiple channels (play modality). Play between toddlers and mothers was frequent, high in symbolic content, and toddler play closely corresponded with mother play in type and modality: Toddlers' nonsymbolic play related to mothers' nonsymbolic play; toddlers' symbolic play related to mothers' symbolic play; toddlers' manual play related to mothers' manual play; and toddlers' multimodal play related to mothers' multimodal play. Play in Mexican-American mothers and toddlers is frequent, multimodal, and symbolically rich, offering new directions for future research and practice.


Subject(s)
Child Behavior/ethnology , Maternal Behavior/ethnology , Mexican Americans/psychology , Mother-Child Relations/ethnology , Play and Playthings/psychology , Adult , Child, Preschool , Female , Humans , Male , Mexico/ethnology , New York City/ethnology , Young Adult
3.
Appl Psychophysiol Biofeedback ; 45(2): 67-74, 2020 06.
Article in English | MEDLINE | ID: mdl-32193714

ABSTRACT

Heart rate variability (HRV) and end tidal CO2 (ETCO2) in relation to treatment response have not been studied in Latino populations or in comorbid asthma and panic disorder (PD). An extension of previously published research, the current study explored psychophysiological variables as possible mediators of treatment response. Latino treatment completers (N = 32) in the Bronx with asthma-PD received either Cognitive-Behavioral Psychophysiological Therapy (CBPT) or Music Relaxation Therapy (MRT). CBPT included HRV-biofeedback (HRVB); in-the-moment heart rate data to help an individual learn to influence his/her own heart rate. The sample was primarily female (93.8%) and Puerto Rican (81.25%). Treatment groups did not differ on demographics, except for less education in CBPT. The Panic Disorder Severity Scale (PDSS) and Asthma Control Questionnaire (ACQ) assessed changes in symptoms. HRV and ETCO2 were measured at four of eight therapy sessions. Baseline ETCO2 and changes in HRV from first to last of psychophysiology sessions were investigated as mediators of change on ACQ and PDSS. Mixed model analyses indicated in the CPBT group, changes in both asthma control and PD severity were not mediated by changes in HRV. In the CBPT and MRT groups combined, changes in PD severity were not mediated by baseline ETCO2. These findings may be due to the brevity of HRVB in CBPT, multiple treatment components, ETCO2 not directly targeted, and/or unique physiological pathways in Latinos with asthma-PD.


Subject(s)
Asthma/rehabilitation , Biofeedback, Psychology , Carbon Dioxide/metabolism , Cognitive Behavioral Therapy , Heart Rate/physiology , Hispanic or Latino , Music Therapy , Outcome Assessment, Health Care , Panic Disorder/rehabilitation , Relaxation Therapy , Adult , Aged , Asthma/ethnology , Asthma/metabolism , Asthma/physiopathology , Biofeedback, Psychology/methods , Cognitive Behavioral Therapy/methods , Female , Humans , Male , Middle Aged , Music Therapy/methods , New York City/ethnology , Panic Disorder/ethnology , Panic Disorder/metabolism , Panic Disorder/physiopathology , Puerto Rico/ethnology , Relaxation Therapy/methods
4.
Child Dev ; 91(3): 1044-1055, 2020 05.
Article in English | MEDLINE | ID: mdl-31325160

ABSTRACT

Sexual attraction (SA), the earliest stage of sexual orientation, is scarcely studied. This prospective study examined, over 3 years, prevalence, changes in SA, and the role of context, among 946 Puerto Rican youth, aged 11-13 years at initial assessment in the South Bronx (SBx), New York City, and Puerto Rico (PR). Overall, 98.1% of boys and 95.3% of girls reported opposite-sex only SA at some point, whereas 13.8% of girls and 12.0% of boys reported any-same SA. Opposite-sex only SA increased over time, whereas other SAs decreased except for any same-sex SA among SBx girls. Girls in the SBx and younger youth in PR reported more any same-sex SA. Context and culture may play a role in the developmental trajectories of adolescents' SA.


Subject(s)
Adolescent Behavior/ethnology , Adolescent Development , Heterosexuality/ethnology , Homosexuality/ethnology , Sexual Behavior/ethnology , Adolescent , Child , Female , Humans , Male , New York City/ethnology , Prospective Studies , Puerto Rico/ethnology
5.
Ann Behav Med ; 54(4): 223-236, 2020 03 24.
Article in English | MEDLINE | ID: mdl-31586174

ABSTRACT

BACKGROUND: Little research has been conducted that integrates, in one explanatory model, the multitude of factors potentially leading to disparities among Latino children. PURPOSE: A longitudinal, observational study tested an explanatory model for disparities in asthma control between Mexican and Puerto Rican children with persistent asthma requiring daily controller medication use. METHODS: Mexican and Puerto Rican children aged 5-12 years (n = 267) and their caregivers (n = 267) were enrolled and completed interviews and child spirometry at baseline and 3, 6, 9, and 12 months postenrollment. A 12 month retrospective children's medical record review was completed. Participants were recruited from two school-based health clinics and the Breathmobile in Phoenix, AZ, and two inner-city hospital asthma clinics in the Bronx, NY. RESULTS: Statistically significant differences in the social/contextual predictors of asthma illness representations (IRs) were noted between Mexican and Puerto Rican caregivers. The structural equation model results revealed differences in asthma control over time by ethnicity. This model accounted for 40%-48% of the variance in asthma control test scores over 12 months. Caregivers' IRs aligned with the professional model of asthma management were associated with better children's asthma control across 1 year. These results also supported the theoretical notion that IRs change over time impacting caregivers' treatment decisions and children's asthma control. CONCLUSIONS: These findings extend a previous cross-sectional model test using a more comprehensive model and longitudinal data and highlight the importance of considering within-group differences for diagnosis and treatment of children coming from the vastly heterogeneous Latino umbrella group. TRIAL REGISTRATION: Trial number NCT01099800.


Subject(s)
Asthma/ethnology , Asthma/nursing , Caregivers/statistics & numerical data , Health Status Disparities , Hispanic or Latino/statistics & numerical data , Arizona/ethnology , Child , Child, Preschool , Female , Humans , Longitudinal Studies , Male , Mexican Americans/statistics & numerical data , Models, Statistical , New York City/ethnology , Puerto Rico/ethnology , Retrospective Studies
6.
J Int Neuropsychol Soc ; 25(9): 901-909, 2019 10.
Article in English | MEDLINE | ID: mdl-31387659

ABSTRACT

OBJECTIVES: Low educational attainment is a risk factor for more rapid cognitive aging, but there is substantial variability in cognitive trajectories within educational groups. The aim of this study was to determine the factors that confer resilience to memory decline within educational strata. METHODS: We selected 2573 initially nondemented White, African American, and Hispanic participants from the longitudinal community-based Washington Heights/Inwood Columbia Aging Project who had at least two visits. We estimated initial memory (intercept) and the rate of memory decline (slope) using up to five occasions of measurement. We classified groups according to the educational attainment groups as low (≤5 years), medium (6-11 years), and high (≥12 years). We used a multiple-group latent growth model to identify the baseline predictors of initial memory performance and rate of memory decline across groups. The model specification considered the influence of demographic, socioeconomic, biomedical, and cognitive variables on the intercept and the slope of memory trajectory. RESULTS: Our results indicated that the three educational groups do not benefit from the same factors. When allowed to differ across groups, the predictors were related to cognitive outcomes in the highly educated group, but we found no unique predictor of cognition for the low educated older adults. CONCLUSIONS: These findings highlight that memory-protective factors may differ across older adults with distinct educational backgrounds, and the need to evaluate a broader range of potential resilience factors for older adults with few years of school.


Subject(s)
Cognitive Aging , Cognitive Dysfunction , Educational Status , Memory Disorders , Memory, Episodic , Aged , Aged, 80 and over , Cognitive Aging/physiology , Cognitive Dysfunction/ethnology , Cognitive Dysfunction/physiopathology , Female , Humans , Longitudinal Studies , Male , Memory Disorders/ethnology , Memory Disorders/physiopathology , New York City/ethnology , Socioeconomic Factors
7.
J Child Psychol Psychiatry ; 60(2): 169-177, 2019 02.
Article in English | MEDLINE | ID: mdl-30052268

ABSTRACT

BACKGROUND: Parenting behaviors have been shown to moderate the association between sensation seeking and antisocial behaviors. METHODS: Data were obtained from the Boricua Youth Study, a longitudinal study of 2,491 Puerto Rican youth living in the South Bronx, New York, and the metropolitan area of San Juan, Puerto Rico. First, we examined the prospective relationship between sensation seeking and antisocial behaviors across 3 yearly waves and whether this relationship varied by sociodemographic factors. Second, we examined the moderating role of parenting behaviors-including parental monitoring, warmth, and coercive discipline-on the prospective relationship between sensation seeking and antisocial behaviors. RESULTS: Sensation seeking was a strong predictor of antisocial behaviors for youth across two different sociocultural contexts. High parental monitoring buffered the association between sensation seeking and antisocial behaviors, protecting individuals with this trait. Low parental warmth was associated with high levels of antisocial behaviors, regardless of the sensation seeking level. Among those with high parental warmth, sensation seeking predicted antisocial behaviors, but the levels of antisocial behaviors were never as high as those of youth with low parental warmth. CONCLUSIONS: Study findings underscore the relevance of person-family context interactions in the development of antisocial behaviors. Future interventions should focus on the interplay between individual vulnerabilities and family context to prevent the unhealthy expression of a trait that is present in many individuals.


Subject(s)
Adolescent Behavior/ethnology , Hispanic or Latino , Juvenile Delinquency/ethnology , Parent-Child Relations/ethnology , Parenting/ethnology , Social Behavior , Adolescent , Child , Child, Preschool , Female , Humans , Longitudinal Studies , Male , New York City/ethnology , Puerto Rico/ethnology
8.
Lupus ; 27(12): 1989-1995, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30092732

ABSTRACT

Objectives Hispanics with systemic lupus erythematosus (SLE) in the United States have more severe disease and damage accrual compared with whites. Data on Hispanics of similar ancestry in geographically different locations is limited but essential in defining genetic and environmental factors for SLE. This study evaluates SLE disease burden in two Dominican communities, Washington Heights in New York City (NYC) and Santiago in the Dominican Republic (DR). Methods Disease activity (SLE Disease Activity Index 2000 (SLEDAI-2K)) and damage (Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI)) were cross-sectionally measured in 76 Dominican SLE patients from the Columbia University Lupus Cohort in NYC and compared with 75 Dominican SLE patients living in Santiago in the DR. Results Mean (±SD) age was 40 (±14) and 36 (±11) years for NYC and DR patients, respectively. Median disease duration was 8 years. Disease activity was mild in both groups (SLEDAI-2K of 3 in NYC versus 4 in the DR). NYC Dominicans had more discoid lesions, positive anti-dsDNA, and anti-SSB antibodies. Dominicans in the DR used more corticosteroids, had less medical insurance, lower educational level, and were more likely to be unemployed, whereas more Dominicans in NYC smoked. NYC patients had a higher SDI compared with SLE patients in the DR (0.96 versus 0.24, p < 0.0001). Statistical significance was maintained in adjusted analysis (1.26 versus 0.57, p < 0.0001). Conclusion SLE Dominican patients in NYC had a higher SDI than those in the DR. Longitudinal studies are needed to ascertain whether this difference is due to biological, environmental factors, immigration patterns or a survival bias.


Subject(s)
Lupus Erythematosus, Systemic/ethnology , Lupus Erythematosus, Systemic/physiopathology , Severity of Illness Index , Adrenal Cortex Hormones/therapeutic use , Adult , Disease Progression , Dominican Republic , Female , Hispanic or Latino , Humans , Linear Models , Lupus Erythematosus, Systemic/drug therapy , Male , Middle Aged , Multivariate Analysis , New York City/ethnology
9.
Am J Health Behav ; 41(5): 561-570, 2017 Sep 01.
Article in English | MEDLINE | ID: mdl-28760178

ABSTRACT

OBJECTIVE: We evaluated the influence of psychosocial factors on HBV screening. METHODS: Sample consisted of 1716 Vietnamese participants in our previous HBV intervention trial, recruited from 36 community-based organizations in Pennsylvania, New Jersey, and New York City between 2009 and 2014. Using the Health Belief Model and Social Cognitive Theory, we measured self-efficacy, knowledge, perceived barriers, perceived benefits, perceived severity, and risk susceptibility. Analysis of covariance was used to compare pre- and post-intervention changes of psychosocial variables. Structural equation modeling was used to explore the direct and indirect effects of the psychosocial variables on HBV screening. RESULTS: Knowledge, self-efficacy, perceived benefits, and perceived barriers were directly associated with HBV screening; knowledge had the strongest effect. Perceived severity and risk susceptibility had indirect association with HBV screening through other variables. Indirect paths among the 6 psychosocial variables were also identified. CONCLUSION: To promote HBV screening among Vietnamese Americans, intervention efforts should focus on increasing knowledge, self-efficacy, and perceived benefits, decreasing perceived barriers, and accounting for the dynamic cognitive processing.


Subject(s)
Asian , Health Knowledge, Attitudes, Practice/ethnology , Hepatitis B/diagnosis , Hepatitis B/ethnology , Adult , Female , Humans , Male , New Jersey/ethnology , New York City/ethnology , Pennsylvania/ethnology , Vietnam/ethnology
10.
Gen Hosp Psychiatry ; 45: 85-90, 2017.
Article in English | MEDLINE | ID: mdl-28274345

ABSTRACT

OBJECTIVES: We examined whether the cut-point 10 for the Patient Health Questionnaire-9 (PHQ9) depression screen used in primary care populations is equally valid for Mexicans (M), Ecuadorians (E), Puerto Ricans (PR) and non-Hispanic whites (W) from inner-city hospital-based primary care clinics; and whether stressful life events elevate scores and the probability of major depressive disorder (MDD). METHODS: Over 18-months, a sample of persons from hospital clinics with a positive initial PHQ2 and a subsequent PHQ9 were administered a stressful life event questionnaire and a Structured Clinical Interview to establish an MDD diagnosis, with oversampling of those between 8 and 12: (n=261: 75 E, 71 M, 51 PR, 64 W). For analysis, the sample was weighted using chart review (n=368) to represent a typical clinic population. Receiver Operating Characteristics analysis selected cut-points maximizing sensitivity (Sn) plus specificity (Sp). RESULTS: The optimal cut-point for all groups was 13 with the corresponding Sn and Sp estimates for E=(Sn 73%, Sp 71%), M=(76%, 81%), PR=(81%, 63%) and W=(80%, 74%). Stressful life events impacted screen scores and MDD diagnosis. CONCLUSIONS: Elevating the PHQ9 cut-point for inner-city Latinos as well as whites is suggested to avoid high false positive rates leading to improper treatment with clinical and economic consequences.


Subject(s)
Depressive Disorder, Major/diagnosis , Depressive Disorder, Major/ethnology , Emigrants and Immigrants/statistics & numerical data , Hispanic or Latino/statistics & numerical data , Hospitals, Urban/statistics & numerical data , Patient Health Questionnaire/standards , Safety-net Providers/statistics & numerical data , Stress, Psychological/ethnology , Adult , Ecuador/ethnology , Female , Humans , Male , Mexico/ethnology , Middle Aged , New York City/ethnology , Puerto Rico/ethnology
11.
J Health Psychol ; 22(1): 68-78, 2017 01.
Article in English | MEDLINE | ID: mdl-26231614

ABSTRACT

Perceiving ethnic discrimination can have aversive consequences for health. However, little is known about whether perceiving language-based (how one speaks a second language) discrimination poses the same risks. This study examined whether perceptions of language-based and ethnic discrimination are associated with mental and physical health. Among 132 Mexican and Dominican immigrant women, perceiving ethnic and language-based discrimination each predicted psychological distress and poorer physical health. When examined together, only ethnic discrimination remained a significant predictor. These results emphasize the importance of understanding how perceived ethnic and language-based discrimination play an integral role in the health of Latina immigrant women.


Subject(s)
Emigrants and Immigrants/psychology , Hispanic or Latino/psychology , Multilingualism , Prejudice , Stress, Psychological/psychology , Adult , Dominican Republic/ethnology , Female , Humans , Mexico/ethnology , New York City/ethnology , Stress, Psychological/ethnology
12.
Psychol Health Med ; 22(6): 633-639, 2017 07.
Article in English | MEDLINE | ID: mdl-27666405

ABSTRACT

Ethnic minority children bear a disproportionate amount of the US asthma burden. We compared asthma morbidity and pulmonary function (%FEV1) in two Caribbean groups living in the Bronx, NY: Puerto Rican and Afro-Caribbean children. Caregiver-child dyads (Puerto Rican: n = 113, M age = 9.89 ± 2.05; Afro-Caribbean: n = 47, Mage = 10.35 ± 2.08) responded to sociodemographic and asthma-related questions, and children's %FEV1 was measured. Puerto Rican children had significantly greater (past year) asthma morbidity, yet there were no significant differences in %FEV1. This discrepancy between objective pulmonary function and asthma morbidity suggests the importance of considering sociocultural factors in pediatric asthma care.


Subject(s)
Asthma/ethnology , Black People/ethnology , Hispanic or Latino/statistics & numerical data , Adolescent , Asthma/physiopathology , Caribbean Region/ethnology , Child , Female , Humans , Male , New York City/ethnology , Puerto Rico/ethnology
13.
Am J Health Behav ; 39(3): 441-50, 2015 May.
Article in English | MEDLINE | ID: mdl-25741688

ABSTRACT

OBJECTIVES: To assess heath literacy, health information seeking, and trust in health-related information among Haitian immigrants seen in primary care. METHODS: Health literacy was measured by the Brief Health Literacy Screen (BHLS); items on health information use were from the 2007 Health Information National Trends Survey. RESULTS: BHLS scores differed according to age, education, and survey language. Participants with lower levels of health literacy tended to be more likely to place "a lot" or "some" trust in family and friends and religious organizations and leaders as sources of information about health or medical topics. CONCLUSIONS: Constructing a culturally-tailored and appropriate intervention regarding health promotion requires understanding how the population accesses and conveys health information.


Subject(s)
Emigrants and Immigrants/psychology , Health Literacy , Information Seeking Behavior , Female , Haiti/ethnology , Humans , Male , Middle Aged , New York City/ethnology , Trust
14.
Child Dev ; 85(6): 2339-54, 2014.
Article in English | MEDLINE | ID: mdl-25345480

ABSTRACT

Using longitudinal data, the authors assessed 585 Dominican, Chinese, and African American adolescents (Grades 6-8, M(age) at W1 = 11.83) to determine patterns over time of perceived ethnic-racial discrimination from adults and peers; if these patterns varied by gender, ethnicity, and immigrant status; and whether they are associated with psychological (self-esteem, depressive symptoms) and social (friend and teacher relationship quality, school belonging) adjustment. Two longitudinal patterns for adult discrimination and three longitudinal patterns for peer discrimination were identified using a semiparametric mixture model. These trajectories were distinct with regard to the initial level, shape, and changes in discrimination. Trajectories varied by gender and ethnicity and were significantly linked to psychological and social adjustment. Directions for future research and practice are discussed.


Subject(s)
Adaptation, Psychological , Adolescent Behavior/psychology , Ethnicity/psychology , Interpersonal Relations , Racism/psychology , Social Adjustment , Adolescent , Black or African American/ethnology , Black or African American/psychology , Asian/ethnology , Asian/psychology , Child , Depression/ethnology , Depression/psychology , Dominican Republic/ethnology , Ethnicity/ethnology , Female , Hispanic or Latino/ethnology , Hispanic or Latino/psychology , Humans , Longitudinal Studies , Male , New York City/ethnology , Peer Group , Self Concept
15.
Carcinogenesis ; 35(1): 69-75, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24177223

ABSTRACT

Polycyclic aromatic hydrocarbons (PAH) are a class of chemicals common in the environment. Certain PAH are carcinogenic, although the degree to which genetic variation influences susceptibility to carcinogenic PAH remains unclear. Also unknown is the influence of genetic variation on the procarcinogenic effect of in utero exposures to PAH. Benzo[a]pyrene (B[a]P) is a well-studied PAH that is classified as a probable human carcinogen. Within our New York City-based cohort, we explored interactions between maternal exposure to airborne PAH during pregnancy and maternal and newborn haplotypes (and in one case, a single-nucleotide polymorphism) in key B[a]P metabolism genes on B[a]P-DNA adducts in paired cord blood samples. The study subjects included non-smoking African-American (n = 132) and Dominican (n = 235) women with available data on maternal PAH exposure, paired cord adducts and genetic data who resided in the Washington Heights, Central Harlem and South Bronx neighborhoods of New York City. We selected seven maternal and newborn genes related to B[a]P metabolism, detoxification and repair for our analyses: CYP1A1, CYP1A2, CYP1B1, GSTM3, GSTT2, NQO1 and XRCC1. We found significant interactions between maternal PAH exposure and haplotype on cord B[a]P-DNA adducts in the following genes: maternal CYP1B1, XRCC1 and GSTM3, and newborn CYP1A2 and XRCC1 in African-Americans; and maternal XRCC1 and newborn NQO1 in Dominicans. These novel findings highlight differences in maternal and newborn genetic contributions to B[a]P-DNA adduct formation, as well as ethnic differences in gene-environment interactions, and have the potential to identify at-risk subpopulations who are susceptible to the carcinogenic potential of B[a]P.


Subject(s)
DNA Adducts/genetics , Haplotypes , Maternal Exposure , Polycyclic Aromatic Hydrocarbons/toxicity , Black or African American/genetics , Aryl Hydrocarbon Hydroxylases/genetics , Cohort Studies , Cytochrome P-450 CYP1A2/genetics , Cytochrome P-450 CYP1B1 , DNA Adducts/blood , DNA-Binding Proteins/genetics , Dominican Republic/ethnology , Female , Fetal Blood , Glutathione Transferase/genetics , Humans , Infant, Newborn , NAD(P)H Dehydrogenase (Quinone)/genetics , New York City/ethnology , Polycyclic Aromatic Hydrocarbons/blood , Polymorphism, Single Nucleotide , Pregnancy , Smoking , X-ray Repair Cross Complementing Protein 1
16.
AIDS Behav ; 17(3): 961-75, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23001411

ABSTRACT

The present study examined cognitive and emotional correlates of sexual decision-making among three groups of Dominican adolescents: (a) Dominican youth who were born and raised in New York City, (b) Dominican youth who recently immigrated to New York City from the Dominican Republic, and (c) Dominican adolescents who were born and currently reside in the Dominican Republic. Data were collected via self-administered questionnaires from Dominican mother-adolescent dyads in New York City (n = 1,008) and the Dominican Republic (n = 213). Across groups, positive emotion constructs were consistently among the most important correlates of intentions to engage in sexual intercourse while issues related to STIs and HIV showed the lowest correlations. Interestingly, positive correlations with intentions to engage in intercourse were found among Dominican-residing males, as were positive correlations with intentions among Dominican-residing females. The implications for HIV prevention programs for Dominican youth are discussed.


Subject(s)
Adolescent Behavior , Cognition/physiology , Emotions/physiology , Hispanic or Latino/ethnology , Sexual Behavior , Adolescent , Adolescent Behavior/ethnology , Adolescent Behavior/psychology , Decision Making/physiology , Dominican Republic/ethnology , Female , Health Knowledge, Attitudes, Practice/ethnology , Humans , Male , New York City/ethnology , Sexual Behavior/ethnology , Sexual Behavior/psychology , Surveys and Questionnaires , United States/ethnology
17.
J Urban Hist ; 38(2): 294-318, 2012.
Article in English | MEDLINE | ID: mdl-22826891

ABSTRACT

Urban historians have greatly expanded their geographical purview in recent years, incorporating suburbs and hinterlands into their analysis of social and environmental change. Urban environmental historians and suburban historians have played a critical role in the regionalization of urban history over the last decade. This case study of the development of New York City's water supply reveals the benefits of taking a regional approach to urban history. From the New York Public Library to Central Park's Great Lawn to neighborhood parks, the New York City landscape bears the traces of the continuous development of the city's water network. Expansion of the water system in rural hinterlands enabled municipal officials to put urban reservoirs to new uses, creating some of the city's most beloved public spaces. The rehabilitation of urban infrastructure underscores the intimate linkages between rural development and the urban built environment.


Subject(s)
City Planning , Public Health , Sanitation , Urban Population , Urbanization , Water Supply , City Planning/economics , City Planning/education , City Planning/history , City Planning/legislation & jurisprudence , Drinking Water , History, 19th Century , History, 20th Century , History, 21st Century , New York City/ethnology , Public Health/economics , Public Health/education , Public Health/history , Public Health/legislation & jurisprudence , Sanitation/economics , Sanitation/history , Sanitation/legislation & jurisprudence , Urban Population/history , Urbanization/history , Urbanization/legislation & jurisprudence , Water Supply/economics , Water Supply/history , Water Supply/legislation & jurisprudence
18.
J Environ Monit ; 14(3): 1035-43, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22334237

ABSTRACT

Prenatal mercury exposure and its fetotoxic effects may be of particular concern in urban immigrant communities as a result of possible contributing cultural factors. The most common source of exposure in these communities is ingestion of fish and shellfish contaminated with methylmercury. Other sources of exposure may occur in ritualistic practices associated with Hispanic and Caribbean-based religions. This study 1) assessed total mercury levels in both random urine specimens from pregnant women, and in cord blood; and 2) examined environmental sources of exposure from a convenience sample in a predominantly Caribbean immigrant population in Brooklyn, New York. A questionnaire designed in collaboration with health professionals from the Caribbean community assessed the frequency of fish consumption, ritualistic practices, occupational exposures, and use of dental amalgams and mercury-containing skin and household products. The geometric mean for total mercury in cord blood was 2.14 µg L(-1) (95%CI: 1.76-2.60) (n = 78), and 0.45 µg L(-1) (95%CI: 0.37-0.55) (n = 183) in maternal urine corrected for creatinine (µg g(-1)). Sixteen percent of cord blood mercury levels exceeded the estimated equivalent of U.S. Environmental Protection Agency's Reference Dose (5.8 µg L(-1) blood). Predictors of cord blood mercury included maternal fish consumption and foreign birth of the mother. Predictors of urine mercury included foreign birth of the mother, number of dental amalgams, and special product use. There were no reports of mercury use in ritualistic practices or in cosmetics; however some women reported use of religious medals and charms. This study characterized risk factors for mercury exposure in a sample of urban, predominantly Caribbean-born blacks. Findings may help target interventions in this population, which might include appropriate fish selection and consumption frequency during pregnancy, and safe handling of mercury-containing products in the home.


Subject(s)
Emigrants and Immigrants/statistics & numerical data , Environmental Pollutants/metabolism , Maternal Exposure/statistics & numerical data , Mercury/metabolism , Adolescent , Adult , Diet/statistics & numerical data , Environmental Pollutants/blood , Environmental Pollutants/urine , Female , Fetal Blood/metabolism , Humans , Mercury/blood , Mercury/urine , Middle Aged , New York City/ethnology , Pregnancy , Seafood/statistics & numerical data , West Indies , Young Adult
19.
Alcohol Clin Exp Res ; 36(7): 1205-11, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22316139

ABSTRACT

BACKGROUND: Acculturation to life in the United States is a known predictor of Hispanic drinking behavior. We compare the ability of 2 theoretical models of this effect-sociocultural theory and general stress theory-to account for associations between acculturation and drinking in a sample of Mexican Americans. Limitations of previous evaluations of these theoretical models are addressed using a broader range of hypothesized cognitive mediators and a more direct measure of acculturative stress. In addition, we explore nonlinearities as possible underpinnings of attenuated acculturation effects among men. METHODS: Respondents (N = 2,595, current drinker N = 1,351) were interviewed as part of 2 recent multistage probability samples in a study of drinking behavior among Mexican Americans in the United States. The ability of norms, drinking motives, alcohol expectancies, and acculturation stress to account for relations between acculturation and drinking outcomes (volume and heavy drinking days) were assessed with a hierarchical linear regression strategy. Nonlinear trends were assessed by modeling quadratic effects of acculturation and acculturation stress on cognitive mediators and drinking outcomes. RESULTS: Consistent with previous findings, acculturation effects on drinking outcomes were stronger for women than men. Among women, only drinking motives explained acculturation associations with volume or heavy drinking days. Among men, acculturation was linked to increases in norms, and norms were positive predictors of drinking outcomes. However, adjusted effects of acculturation were nonexistent or trending in a negative direction, which counteracted this indirect normative influence. Acculturation stress did not explain the positive associations between acculturation and drinking. CONCLUSIONS: Stress and alcohol outcome expectancies play little role in the positive linear association between acculturation and drinking outcomes, but drinking motives appear to at least partially account for this effect. Consistent with recent reports, these results challenge stress models of linear acculturation effects on drinking outcomes and provide (partial) support for sociocultural models. Inconsistent mediation patterns-rather than nonlinearities-represented a more plausible statistical description of why acculturation-drinking associations are weakened among men.


Subject(s)
Acculturation , Alcohol Drinking/ethnology , Mexican Americans/ethnology , Adult , Alcohol Drinking/psychology , Arizona/ethnology , California/ethnology , Cross-Sectional Studies , Female , Humans , Male , Mexican Americans/psychology , New Mexico/ethnology , New York City/ethnology , Pennsylvania/ethnology , Texas/ethnology , United States/ethnology
20.
J Immigr Minor Health ; 14(2): 251-8, 2012 Apr.
Article in English | MEDLINE | ID: mdl-21479888

ABSTRACT

Peer outreach models have been successful in addressing HIV risk behaviors of drug users. Patients in methadone maintenance treatment programs who were migrants from Puerto Rico and/or familiar with drug use there were trained to conduct HIV-related peer outreach. A group randomized design was implemented; patients in the Experimental (E) condition (n = 80) received training and conducted 12 weeks of outreach. Half of the patients completed the training and outreach. At follow-up, patients in the E condition who conducted outreach felt they were more helpful to their community, showed a trend for engaging in more vocational activities, and were more likely to talk with others about HIV, compared to those who did not conduct outreach and those in the Control condition (n = 78). Drug treatment patients who are migrants can be trained as peer outreach workers and short-term benefits were found. Longer term maintenance of benefits should be assessed.


Subject(s)
HIV Infections/prevention & control , Hispanic or Latino , Methadone/therapeutic use , Narcotics/therapeutic use , Opiate Substitution Treatment/methods , Peer Group , Adult , Community-Institutional Relations , Emigrants and Immigrants , Female , HIV Infections/ethnology , Humans , Male , Middle Aged , New York City/epidemiology , New York City/ethnology , Puerto Rico/ethnology , Risk-Taking , Sexual Behavior , Social Support , Substance-Related Disorders/ethnology , Substance-Related Disorders/rehabilitation , Treatment Outcome
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