[Hepatitis B prevention after occupational exposure]. / Profylakse mod hepatitis B efter erhvervsmaessig eksposition.

The course of a programme for protection from hepatitis B after occupational exposure is assessed. Passive/active prophylaxis from hepatitis B was offered to 51 persons but only 28% completed the entire regimen. The programme for vaccination of staff prior to exposure must be intensified and not only this programme but also the protective programme after exposure must include reminders to individuals who do not follow the programme.

An outbreak of psittacosis in Minnesota turkey industry workers: implications for modes of transmission and control.

From June through November 1986, an outbreak of psittacosis occurred in turkey industry workers in central Minnesota. A total of 186 suspect cases were identified, and 122 cases (66%) were serologically confirmed. Cases occurred in three turkey processing plants, two rendering plants, one farm, and one "further processing" plant (where meat is removed from previously eviscerated carcasses and consumer products, such as roasts, are made). As in previous outbreaks, workers exposed to the viscera of infected birds were at greatest risk of becoming infected. However, our data showed that 31 (25%) of the confirmed cases occurred in workers at the further processing plant who had contact only with previously eviscerated carcasses. Although the specific source of infection and the mode of transmission in these workers are unclear, the use of gloves and masks by all processing workers during an outbreak might help to limit exposure. Control measures, which focused on identifying and treating ill turkey flocks, were initiated in early September; however, cases continued to occur in turkey industry workers through November. One of the flocks suspected of causing illness appeared healthy and, therefore, was not treated. Chlamydia psittaci infection in this flock was confirmed by culture after the flock had been processed. A rapid test for diagnosing C. psittaci infection in turkey flocks at the time of processing might be useful in preventing exposure of large numbers of workers.

Human immunodeficiency virus infection in health care workers. A method for estimating individual occupational risk.

Physicians and other health care workers are concerned about their occupational risk of acquiring human immunodeficiency virus infection. We have developed an approach that can help health care workers estimate their cumulative risk of infection with human immunodeficiency virus. Illustrations are used to develop a score that reflects an individual's occupational exposures and social behavior. This score is then translated into the probability that the worker is infected.

Do hospital personnel in hyperendemic areas require immunization against hepatitis B virus (HBV) infection? Is vertical transmission of HBV infection common in this group?

Medical personnel working in contact with blood and blood-contaminated body fluids are often considered to be a high-risk group for hepatitis B virus (HBV) infection and, as a result, it is recommended that they should be vaccinated against this infection. To find out if this is necessary in a country hyperendemic for HBV infection and to see if parents transmit the infection to their offspring, a total of 336 volunteer hospital employees, and 103 children of 47 of them, were tested for HBsAg, anti-HBc, anti-HBs, HBeAg and anti-HBe using the radioimmunoassay technique. Of these, 242 (72%) were found to have evidence of past or present HBV infection and only 94 (28%) had no such evidence. The infection prevalence in the 47 parents was 68% comparable to that of the total sample. Only 9 of their 103 children were positive for HBV markers. All tested parents of these positive children were either negative for all markers or positive for anti-HBs. The HBV infection prevalence among this hospital population is not different from that of the general Ethiopian population, and vertical transmission appears unlikely in this group. Therefore, mass vaccination of hospital staff in hyperendemic areas is unnecessary.

Glove perforation during plastic surgery.

Intraoperative perforation of surgical gloves is common. Nine hundred and forty surgical gloves were tested after 100 consecutive plastic surgical operations, each involving a surgeon, a variable number of assistants and a scrub nurse. In the first 52 operations, single gloves were used and 21.5% of the staff were found to have a perforated glove. In the second 48 operations, double gloves were used by all members of the surgical team and the number with perforations (of both inner and outer gloves) was reduced to 9%. Most perforations occurred on the dorsum of the hand and fingers and on the thumb tip, especially in the non-dominant hand. The risk of acquiring AIDS due to glove perforation is low but the consequences of such an event could be lethal.

AIDS: the contamination risk in urological surgery.

Increasing numbers of patients infected with the Human Immunodeficiency Virus (HIV) will be encountered in surgical practice. The risk of exposure to the virus during urological surgery is unknown. In an attempt to quantify the risk and to identify procedures that require change, 427 consecutive urological operations were prospectively assessed for contamination of the surgeon's skin, face and mucous membranes by potentially infected body fluids. Contamination occurred in 136 procedures (32%), of which 37 of 123 (30%) were open operations and 99 of 304 (33%) were endoscopic. Contamination of the face and eyes accounted for 46% (46 of 99 operations) of the contamination occurring in endoscopic surgery. Attention must be paid to reducing exposure of the surgeons' skin to patients' body fluids. The surgeons' eyes should be protected by modification of urological techniques and equipment to avoid spillage.

An avoidable occupational hazard during mastoid surgery.

Conjunctival innoculation is a previously unrecognized hazard for the otologist during mastoid surgery. This experiment assess the spread of droplet contamination during temporal bone dissection. The results suggest that otologists and assistants should wear eye protection during exposure of the mastoid antrum by drilling.

[The psychiatric facility and AIDS]. / Psychiatrische Einrichtung und AIDS.

There is still a lack of interest in problems emerging in the institutional treatment of the psychiatric AIDS-patient. The small number of articles dealing with the treatment of the acute ill is reported. None of them regards the risk of HIV-infection for chronic mental ill or mental retarded persons in greater institutions. Ethical, legal, and practical implications of this problem are discussed.

Increased incidence of Campylobacter pylori infection in gastroenterologists: further evidence to support person-to-person transmission of C. pylori.

The mode transmission of Campylobacter pylori is still unknown, although several studies have suggested person-to-person transmission. In this study the incidence of active C. pylori infection in an endoscopy staff was compared with that in general practitioners and normal blood donors. Since endoscopy workers are in close contact with patients, many of whom would be likely to have active C. pylori infection, it was likely that there would be an increased incidence of active C. pylori infection in endoscopists if the organism can spread from person to person. The incidence of active C. pylori infection in the group of gastroenterologists was 52%, compared with 21% in an age-matched group of blood donors. This finding was statistically significant (p less than 0.01). In comparison, the incidence of active C. pylori infection in the endoscopy nurses and general practitioners was not statistically different from that in the normal population.

Occupational infection with human immunodeficiency virus (HIV). Risks and risk reduction.

As the epidemic of the acquired immunodeficiency syndrome (AIDS) expands, the prevalence of the human immunodeficiency virus (HIV) infection in health care environments will increase and health care workers in many locations are likely to be at increased risk for exposure. The Fifth Annual Advances in Occupational Cancer Conference, held in December 1988 in San Francisco, addressed occupational HIV infection. Symposium participants concluded that the risk of HIV infection for health care workers is low but not zero. Implementation of universal blood and body fluid precautions was agreed to as an appropriate method of preventing exposure to HIV, especially for preventing needlestick accidents. Current standards for hospital waste disposal were judged to be adequate to prevent transmission of HIV, and confidential testing for HIV antibody in health care workers with follow-up counseling was recommended where indicated. It was also agreed that the risk of occupational exposure to HIV does not free health care workers from the responsibility to provide care to infected persons.