Cross-Sectional Survey of Mental Health Risk Factors and Comparison of the Monoamine oxidase A Gene DNA Methylation Level in Different Mental Health Conditions among Oilfield Workers in Xinjiang, China.

The incidence of psychological problems among occupational groups is becoming increasingly more serious, and adverse psychological conditions will seriously affect the working ability of occupational groups and harm the health of their bodies. This study adopted a multi-stage stratified cluster sampling method to conduct a cross-sectional survey on the mental health of 3631 oil workers in Karamay, Xinjiang from March 2017 to June 2018. The mental health status of oil workers was evaluated using the Symptom Checklist-90, and mental health risk factors were evaluated. The correlation between the monoamine oxidase A (MAOA) gene and mental health was analyzed, and the DNA methylation level of the MAOA gene was compared between the normal group and the abnormal group. The results show the incidence of mental health problems among oil workers according to differences in age, nationality, type of work, length of service, professional title, shift work, and marital status. The evaluation of mental health risk factors revealed that shift work, occupational stress, and high payment/low return affect mental health. The somatization scores of different genotypes of rs6323 in the MAOA gene were statistically significant (p < 0.05), suggesting that the somatization scores of different genotypes of rs6323 were different. According to the average rank, the TT genotype group had the highest score, followed by the GT genotype group, and the GG genotype group had the lowest score. The level of DNA methylation in the abnormal group was lower than that in the normal group (p < 0.05). The results suggested that occupational mental health can be enhanced by improving shift work, reducing stress, and balancing effort and reward. This preliminary investigation suggests that methylation status can affect mental health, indicating that methylation level may be a predictor of mental health status.

Work stress, personality traits, and cortisol secretion: Testing a model for job burnout.

BACKGROUND: Job stressors can cause a salivary cortisol secretion dysregulation which in turn can lead to burnout. However, job stressors do not induce the same cortisol secretion dysregulation and psychic consequences systematically to all workers. Personality traits may influence job stressor's adaptation. The objectives of this study were (a) to verify the mediating effect cortisol has on the relationship between work conditions and burnout, and (b) to identify the moderate mediation effects that personality traits have on the relationship between work conditions and salivary cortisol secretion. METHOD: Multilevel regression analyses were carried out on a sample of 352 employees in 34 Québec firms. Saliva samples were collected five times a day (on awakening, 30 minutes after awakening, at 2 p.m., 4 p.m., and bedtime) on three days (1 day off, 2 work days). Work conditions variables comprised skill utilization, decision authority, psychological demands, physical demands, job insecurity, irregular schedules, number of working hours, and social support. Personality traits included self-esteem, locus of control, and the Big Five. Both work conditions and personality traits were assessed with a psychosocial questionnaire. RESULTS: The level of salivary cortisol secretion was negatively associated with burnout. Certain workplace and personality variables had a significant effect on emotional exhaustion (psychological demands was positively associated, social support from supervisors was negatively associated) and on cortisol levels (job insecurity was negatively associated). Cortisol did not play any mediating role in the relationship between work conditions and burnout, which is moderated by personality traits. CONCLUSIONS: We conclude that work conditions (skill utilization, decision authority, psychological demands, physical demands, job insecurity, irregular schedules, number of working hours, and social support) and the interaction of personality traits with work conditions have no indirect effects on burnout.