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1.
BMC Womens Health ; 24(1): 274, 2024 May 04.
Article in English | MEDLINE | ID: mdl-38704534

ABSTRACT

BACKGROUND: Giant ovarian cysts (GOCs)complicated with progressive bulbar paralysis (PBP) are very rare, and no such literature about these cases have been reported. Through the diagnosis and treatment of this case, the perioperative related treatment of such patients was analyzed in detail, and early-stage ovarian mucinous carcinoma was unexpectedly found during the treatment, which provided reference for clinical diagnosis and treatment of this kind of diseases. CASE PRESENTATION: In this article, we reported a 38-year-old female patient. The patient was diagnosed with PBP 2 years ago. Examination revealed a large fluid-dominated cystic solid mass in the pelvis measuring approximately 28.6×14.2×8.0 cm. Carbohydrate antigen19-9(CA19-9) 29.20 IU/mL and no other significant abnormalities were observed. The patient eventually underwent transabdominal right adnexal resection under regional anesthesia, epidural block. Postoperative pathology showed mucinous carcinoma in some areas of the right ovary. The patient was staged as stage IA, and surveillance was chosen. With postoperative follow-up 1 month later, her CA19-9 decreased to 14.50 IU/ml. CONCLUSIONS: GOCs combined with PBP patients require a multi-disciplinary treatment. Preoperative evaluation of the patient's PBP progression, selection of the surgical approach in relation to the patient's fertility requirements, the nature of the ovarian cyst and systemic condition are required. Early mucinous ovarian cancer accidentally discovered after operation and needs individualized treatment according to the guidelines and the patient's situation. The patient's dysphagia and respiratory function should be closely monitored during the perioperative period. In addition, moral support from the family is also very important.


Subject(s)
Adenocarcinoma, Mucinous , Ovarian Neoplasms , Humans , Female , Adult , Ovarian Neoplasms/complications , Ovarian Neoplasms/surgery , Ovarian Neoplasms/diagnosis , Adenocarcinoma, Mucinous/complications , Adenocarcinoma, Mucinous/surgery , Adenocarcinoma, Mucinous/diagnosis , Perioperative Care/methods , Ovarian Cysts/surgery , Ovarian Cysts/complications , Ovarian Cysts/diagnosis , Neoplasm Staging
2.
BMJ Case Rep ; 17(3)2024 Mar 08.
Article in English | MEDLINE | ID: mdl-38458762

ABSTRACT

Long-standing, overt hypothyroidism-induced bilateral multiloculated ovarian cysts represent an infrequent occurrence. Our first case, presented with bilateral complex ovarian masses, exhibited overt hypothyroidism symptoms, including lethargy, weight gain and subfertility, prompting consideration for surgical intervention. Similarly, in the second case, a girl aged 11 years with stunting, delayed bone age and academic challenges was referred for surgical exploration due to bilateral complex ovarian masses. Both cases revealed elevated thyroid-stimulating hormone levels during preoperative workup. Commencing levothyroxine replacement therapy resulted in complete regression of ovarian cysts and substantial symptom improvement within an 8-week timeframe. The third case, a previously diagnosed patient with Hashimoto's thyroiditis, benefited from the lessons gleaned in managing the initial cases, responding well to levothyroxine therapy, thereby averting the necessity for surgery in all three instances. These cases underscore the significance of considering thyroid function in the evaluation of ovarian masses and highlight the efficacy of levothyroxine replacement therapy in resolving both hypothyroidism and associated ovarian cysts, thereby obviating the need for surgical intervention.


Subject(s)
Hypothyroidism , Ovarian Cysts , Ovarian Neoplasms , Thyroiditis, Autoimmune , Female , Humans , Thyroxine/therapeutic use , Thyroiditis, Autoimmune/complications , Hypothyroidism/complications , Hypothyroidism/drug therapy , Hypothyroidism/diagnosis , Ovarian Cysts/complications , Ovarian Cysts/surgery , Ovarian Cysts/diagnosis , Ovarian Neoplasms/complications
3.
BMJ Case Rep ; 17(1)2024 Jan 29.
Article in English | MEDLINE | ID: mdl-38286579

ABSTRACT

An adolescent female presented with an acute abdomen and elevated beta-human chorionic gonadotropin levels and underwent a laparoscopy for a suspected ruptured ectopic pregnancy. Intraoperatively, a ruptured haemorrhagic corpus luteal cyst and tissues suggestive of products of conception were noted in the same ovary. Histology confirmed an ovarian ectopic pregnancy. Haemorrhagic ovarian cysts, and ectopic pregnancies, can cause acute pelvic pain in women of childbearing age. Their similar clinical signs and symptoms pose a diagnostic dilemma for any gynaecologist. Ruptured corpus luteal cysts, as well as ruptured ovarian ectopic pregnancies, should be considered rare but differential diagnoses in women presenting with acute abdominal pain, an adnexal mass and ultrasound features of haemoperitoneum. The mainstay of treatment is a diagnostic laparoscopy, which is a safe and feasible management strategy without compromising patient safety or ovarian function in the long run.


Subject(s)
Abdomen, Acute , Cysts , Ovarian Cysts , Pregnancy, Ectopic , Pregnancy, Ovarian , Pregnancy , Adolescent , Female , Humans , Hemoperitoneum/diagnostic imaging , Hemoperitoneum/etiology , Hemoperitoneum/surgery , Rupture, Spontaneous/complications , Rupture, Spontaneous/surgery , Pregnancy, Ectopic/diagnostic imaging , Pregnancy, Ectopic/surgery , Ovarian Cysts/complications , Ovarian Cysts/surgery , Ovarian Cysts/diagnosis , Rupture/complications , Abdomen, Acute/etiology , Cysts/complications
4.
Clin Endocrinol (Oxf) ; 100(1): 29-35, 2024 01.
Article in English | MEDLINE | ID: mdl-37386805

ABSTRACT

OBJECTIVE: Peripheral precocious puberty (PPP) is the precocious development of secondary sexual characteristics without pulsatile gonadotropin-releasing hormone (GnRH) secretion. In girls, PPP suggests a hyper-oestrogenic state, such as autonomous ovarian cysts and McCune-Albright syndrome (MAS). We aimed to investigate PPP in girls with ovarian cysts, with or without MAS. DESIGN: A retrospective study design was used. PATIENTS AND MEASUREMENTS: The study included 12 girls diagnosed with ovarian cysts with PPP between January 2003 and May 2022. Pelvic sonography was performed in cases of vaginal bleeding or areolar pigmentation in PPP. The clinical characteristics, clinical course and pelvic sonographic findings of girls with ovarian cysts were investigated. RESULTS: We found 18 episodes of ovarian cysts in the 12 girls. The median size of the ovarian cysts was 27.5 mm. Five of the girls were diagnosed with MAS. The median time to spontaneous regression was 6 months. Later, 4 out of 12 girls progressed to central precocious puberty (CPP), and three of them had a recurrence of ovarian cysts. Compared to the non-recurrent and recurrent groups, there was a difference in peak luteinizing hormone (LH) in the GnRH stimulation test and period to cyst regression. CONCLUSIONS: Most ovarian cysts in PPP spontaneously disappear. However, this could be one of the findings of MAS. Some girls progress from PPP to CPP. Therefore, follow-up is necessary for ovarian cysts in patients with PPP. The recurrence of ovarian cysts may occur when spontaneous regression is prolonged.


Subject(s)
Fibrous Dysplasia, Polyostotic , Ovarian Cysts , Puberty, Precocious , Female , Humans , Puberty, Precocious/diagnosis , Retrospective Studies , Remission, Spontaneous , Ovarian Cysts/complications , Ovarian Cysts/diagnosis , Gonadotropin-Releasing Hormone , Fibrous Dysplasia, Polyostotic/complications , Follicle Stimulating Hormone
5.
Pan Afr Med J ; 45: 93, 2023.
Article in English | MEDLINE | ID: mdl-37692981

ABSTRACT

Intestinal obstruction due to adnexal torsion is a rare complication that can be occurred during torsion of an ovarian cyst. A premenopausal woman presented to the emergency department with complaints of abdominal distension, abdominal pain, and obstipation for 2 days. An abdominal radiograph showed signs of large bowel partial obstruction. Hence admission to the surgical department was ordered. Due to deterioration of the patient, a gynaecological evaluation took place. Ultrasonography demonstrated a large ovarian cyst, which was also confirmed by an abdominal computed tomography scan and thus immediate laparotomy was decided. Abdominal hysterectomy with bilateral salpingo-oophorectomy was performed due to torsion of a giant ovarian cyst, which caused intestinal obstruction by compression. The post-operative course of the patient was uneventful. Ovarian torsion should not be eliminated from differential diagnosis when it comes to female patients with clinical presentation relevant to small and/or large bowel obstruction.


Subject(s)
Intestinal Obstruction , Ovarian Cysts , Humans , Female , Intestinal Obstruction/etiology , Intestinal Obstruction/surgery , Abdominal Pain/etiology , Diagnosis, Differential , Ovarian Cysts/complications , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery , Ovarian Torsion , Premenopause
6.
Rev Fac Cien Med Univ Nac Cordoba ; 80(2): 156-157, 2023 06 30.
Article in Spanish | MEDLINE | ID: mdl-37402307

ABSTRACT

The term pseudoascitis is used in patients who give the false impression of ascites, with abdominal distension but without peritoneal free fluid. The case of a 66-year-old woman, hypertensive and hypothyroid with occasional alcohol consumption, who consults due to progressive abdominal distension of 6 months of evolution and diffuse percussion dullness is presented, in whom a paracentesis is performed with the wrong endorsement of examination ultrasound that reports abundant intrabdominal free fluid (Fig. 1), later finding in the CT scan of the abdomen and pelvis an expansive process of cystic appearance of 295mm x 208mm x 250mm. Left anexectomy is programmed (Fig. 2) with pathological report of mucinous ovarian cystadenoma. The case report refers to the availability of the giant ovarian cyst within the differential diagnosis of ascites. If no symptoms or obvious signs of liver, kidney, heart or malignant disease are found and / or ultrasound does not reveal typical signs of intra-abdominal free fluid (fluid in the bottom of the Morrison or Douglas sac, presence of floating free intestinal handles), a CT scan and / or an RMI should be requested before performing paracentesis, which could have potentially serious consequences.


El término pseudoascitis, se utiliza en los pacientes que dan la falsa impresión de ascitis, con distensión abdominal pero sin líquido libre peritoneal. Se presenta el caso de una mujer de 66 años, hipertensa e hipotiroidea con consumo ocasional de alcohol, que consulta por distensión abdominal progresiva de 6 meses de evolución y matidez difusa a la percusión, en quien se realiza una paracentesis con el aval equivoco de examen ecográfico que informa abundante líquido libre  intrabdominal (Fig. 1), hallando posteriormente en TAC de abdomen y pelvis un proceso expansivo de aspecto quístico de 295mm x 208mm x 250mm. Se programa anexectomia izquierda (Fig. 2) con informe anatomopatológico de cistoadenoma mucinoso de ovario. La comunicación del caso remite a tener disponible el quiste ovárico gigante dentro de los diagnósticos diferenciales de ascitis. Si no se hallan síntomas o signos evidentes de insuficiencia hepática, renal, cardiaca o enfermedad maligna y/o la ecografía no revela signos típicos de líquido libre intrabdominal  (líquido en el fondo de saco de Morrison o de Douglas, presencia de asas intestinales libres flotantes), se debería solicitar una TAC y/o una RMI antes de realizar una paracentesis, la cual podría tener consecuencias potencialmente graves.


Subject(s)
Cystadenoma, Mucinous , Ovarian Cysts , Ovarian Neoplasms , Female , Humans , Aged , Ascites/diagnostic imaging , Ascites/etiology , Cystadenoma, Mucinous/diagnosis , Cystadenoma, Mucinous/pathology , Ovarian Neoplasms/diagnosis , Ovarian Cysts/diagnosis , Kidney
7.
JBRA Assist Reprod ; 27(3): 572-575, 2023 09 12.
Article in English | MEDLINE | ID: mdl-37417850

ABSTRACT

An ovarian benign cyst is a common finding in women of reproductive age. However both the disease and its treatment may have an impact on ovarian reserve, resulting in a significant risk of premature ovarian insufficiency. The counselling on fertility preservation is of paramount importance in such cases. We report the management of a young woman with giant bilateral benign adnexal cysts, highlighting the complexity of fertility preservation in such scenario.


Subject(s)
Fertility Preservation , Ovarian Cysts , Ovarian Neoplasms , Female , Humans , Fertility Preservation/methods , Ovarian Cysts/complications , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery , Reproduction
8.
J Pak Med Assoc ; 73(6): 1302-1304, 2023 Jun.
Article in English | MEDLINE | ID: mdl-37427636

ABSTRACT

A 27-year-old married woman came to the emergency room (ER) with the chief complaint of severe pain in the abdomen for 3 days, which was more pronounced in the right iliac fossa, along with the complaint of multiple episodes of vomiting for the last 6 hours. She also gave a history of swelling in the right inguinal region for last 9 months with the complaint of mild on and off pain in the swelling. On physical examination, diagnosis of obstructed inguinal hernia was made. Ultrasonography (USG) of abdomen was of no use, as it only commented on hernial defect and not on the contents of the hernial sac. An emergency surgery was planned; marsupialisation of ovarian cyst, repositioning of fallopian tube along with ovary and herniorrhaphy was performed without any difficulty.


Subject(s)
Hernia, Inguinal , Herniorrhaphy , Ovarian Cysts , Adult , Female , Humans , Abdominal Cavity , Fallopian Tubes/surgery , Hernia, Inguinal/diagnosis , Hernia, Inguinal/diagnostic imaging , Hernia, Inguinal/surgery , Ovarian Cysts/diagnosis , Ovarian Cysts/diagnostic imaging , Ovarian Cysts/surgery , Herniorrhaphy/methods
9.
Reprod Biol Endocrinol ; 21(1): 59, 2023 Jun 27.
Article in English | MEDLINE | ID: mdl-37370122

ABSTRACT

OBJECTIVE: This study aimed to explore the optimal time of laparoscopic cystectomy for unilateral ovarian endometrioma patients and evaluate the influence on ovarian reserve. MATERIALS AND METHODS: This prospective randomized controlled study included 88 women with unilateral ovarian endometrioma at a tertiary teaching hospital. All patients received their first identified diagnosis of ovarian endometrioma by ultrasound (> 4 cm and ≤ 10 cm) and were administered an oral contraceptive pill (OC) for one cycle before laparoscopy. They were randomly divided into two groups: laparoscopy at the late luteal phase (group LLP) (n = 44) (termination of OC for two days) and laparoscopy at the early follicular phase (group EFP) (n = 44) (day 3 after menstruation). Basic clinical characteristics were recorded. Serum Anti-Müllerian hormone (AMH) levels were measured at various times to predict ovarian reserve. Serum levels of Anti-Müllerian hormone (AMH) were measured at several time sites to predict the ovarian reserve; AMH and leukocyte esterase (LE) levels of the endometrioma wall were measured. RESULTS: Before surgery, serum AMH levels decreased in both groups from preoperative to one week and six months postoperatively. In contrast, the difference values of group EFP were larger than those of group LLP at postoperative one week and postoperative six months (1.87 ± 0.97 vs. 1.31 ± 0.93, P = 0.07; 1.91 ± 1.06 vs. 1.54 ± 0.93, P = 0.001). The mean rates of postoperative serum AMH decline were 37.92% and 46.34% in group EFP, significantly higher than those in group LLP (25.83% vs. 31.43%, P < 0.001). Ovarian endometrioma wall AMH of group LLP was significantly lower than that of group EFP ([22.86 ± 3.74] vs. [31.02 ± 5.23], P < 0.001). Meanwhile, ovarian endometrioma LE concentration of group LLP was significantly higher than that of group EFP ([482.83 ± 115.88] vs. [371.68 ± 84.49], P<0.001). There was also a significant inverse correlation between leukocyte esterase and AMH concentration in an ovarian endometrioma cyst wall (r=-0.564, P<0.001). CONCLUSION(S): The optimal time for laparoscopic cystectomy for patients with first identified unilateral ovarian endometrioma is the late luteal phase, which reduces ovarian tissue loss and preserves ovarian reserve effectively and safely.


Subject(s)
Endometriosis , Laparoscopy , Ovarian Cysts , Ovarian Reserve , Humans , Female , Endometriosis/surgery , Prospective Studies , Anti-Mullerian Hormone , Ultrasonography , Ovarian Cysts/surgery , Ovarian Cysts/diagnosis
10.
Pan Afr Med J ; 44: 33, 2023.
Article in English | MEDLINE | ID: mdl-37034490

ABSTRACT

Acute abdominal pain in adolescents has a multitude of diagnoses to consider ranging from life-threating ones to other less obvious. In this case report, a 15-year-old girl presented with right lower quadrant abdominal pain and tenderness one month after successful surgical management of acute appendicitis. Post-appendectomy abdominal pain could easily be attributed to post-operative complications, while, in reality, a different disease state may be the cause of the pain. Physicians should have a high index of clinical suspicion, even though the temporal association of events may suggest otherwise. Hemorrhagic ovarian cyst (HOC) should be included in the differential, as it was confirmed with imaging in our case. A conservative treatment approach with progesterone was chosen, with menses resuming 2 days later, leading to regression of the cyst. The clinical significance of this case relies on the timely recognition of a disease entity, in order to distinguish it from complications arising postoperatively.


Subject(s)
Abdomen, Acute , Appendicitis , Ovarian Cysts , Female , Adolescent , Humans , Appendectomy/methods , Abdominal Pain/complications , Appendicitis/diagnosis , Appendicitis/surgery , Appendicitis/complications , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery
11.
Pan Afr Med J ; 44: 42, 2023.
Article in English | MEDLINE | ID: mdl-37070025

ABSTRACT

A case of a 53-year-old postmenopausal woman presenting a giant ovarian cystic mucinous tumor weighing 24 kg is reported here. When she was seen first at our outpatient clinic, she had gross abdominal distension since 2 years, and she complained of unbearable aggressive pain. Her computed tomography (CT) scan was done which came suggestive of ovarian serous cystadenoma of large massive size 35 x 40 x 32 cm with moderate ascites. On exploratory laparotomy, a giant, totally cystic, vascularized and smooth mass attached to the right ovary was encountered. On the postoperative tenth day, she was discharged without any problem. Histopathology report of the right ovarian cystic mass came suggestive of multiloculated cyst with capsule intact with Borderline Mucinous tumor of right ovary weighing 24 kg. This is both one of the largest known examples in the literature and the largest ovarian cyst ever seen at our institution.


Subject(s)
Cystadenoma, Mucinous , Ovarian Cysts , Ovarian Neoplasms , Humans , Female , Middle Aged , Cystadenoma, Mucinous/diagnosis , Cystadenoma, Mucinous/surgery , Cystadenoma, Mucinous/pathology , Postmenopause , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/surgery , Ovarian Neoplasms/pathology , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery , Ascites
12.
Medicina (Kaunas) ; 59(2)2023 Jan 17.
Article in English | MEDLINE | ID: mdl-36837388

ABSTRACT

Abdominal cystic masses are diagnosed during the intrauterine period and have a relatively low incidence. Fetal ovarian cysts are the most common form diagnosed prenatally or immediately after birth. The pathophysiology of the development of these types of tumors is not fully elucidated, with ovarian hyperstimulation caused by maternal and placental hormones being the most accepted hypothesis. During intrauterine development, the diagnosis of fetal ovarian cysts is most often made accidentally during usual check-up ultrasounds corresponding to the first, second, and third trimesters of pregnancy. We conducted a scoping review with the aim to map the current knowledge regarding the treatment of fetal ovarian cysts diagnosed in the intrauterine period. Focusing on the articles published in the last 10 years in the specialized literature, we tried to identify a conceptualization regarding the surveillance and treatment of these anomalies.


Subject(s)
Ovarian Cysts , Ultrasonography, Prenatal , Pregnancy , Female , Humans , Placenta , Ovarian Cysts/diagnosis , Ovarian Cysts/therapy , Pregnancy Trimester, Third
13.
Z Gastroenterol ; 61(2): 172-177, 2023 Feb.
Article in English | MEDLINE | ID: mdl-36470286

ABSTRACT

BACKGROUND: Acute epiploic appendagitis is a rare differential diagnosis of unclear or acute abdomen. AIM: To describe - by means of a scientific case report - the extraordinary diagnosis of acute epiploic appendagitis along with contained diverticulitis and incarcerated herniation of the greater omentum into the hernial sac of a former trocar site (medical history, significant for laparoscopic ovarian cyst removal) in a 29-year-old female based on experiences obtained in the successful clinical case management, and on selective references from medical scientific literature. CASE SUMMARY: Medical history: A 29-year-old female was admitted with abdominal pain in the lower left quadrant. She reported a laparoscopic ovarian cyst removal 3 years prior. Physical examination of the abdomen revealed tenderness in the lower left quadrant without a palpable mass.Leading diagnoses were found using transabdominal ultrasound and confirmed by an abdominal CT scan; namely, incarcerated trocar hernia, diverticulitis of sigmoid colon, and acute epiploic appendagitis. Therapeutic approach was comprised of an explorative laparoscopy (because of the incarcerated hernia), adhesiolysis, removal of a tip of the greater omentum out of the hernial sac, closure of the hernial orifice, and removal of an unclear, inflamed, and bloody fatty tissue from the wall of the descending colon (histopathological investigation confirmed acute epiploic appendagitis). This was flanked by conservative treatment of diverticulitis of the sigmoid colon.Further clinical course was uneventful, with discharge on the 3rd postoperative day with favorable long-term outcome, characterized by no further complaints for 15 months. DISCUSSION: Acute epiploic appendagitis is an inflammatory, usually self-limiting condition of the epiploic appendages of the colon. It typically manifests with abdominal pain in the lower left quadrant. Imaging is an important diagnostic tool to determine whether the patient has, in fact, acute epiploic appendagitis, so recognizing the characteristic oval lesions with the surrounding inflammation and central fat attenuation on CT, as well as the hyperechoic oval lesions with a hypoechoic peripheral band on ultrasound images is crucial. Nevertheless, it is often overlooked in patients and confused with other differential diagnoses, such as appendicitis or diverticulitis. Although the condition appears infrequently, it is essential to be proficient in the diagnostic evaluation, as a misdiagnosis may lead to unnecessary treatment and even surgical intervention. IN CONCLUSION: , the patient was initially diagnosed with an incarcerated abdominal hernia, and therefore subsequently underwent surgery. The inflamed epiploic appendage was discovered in laparoscopic exploration, removed, and confirmed through the histopathology report. This is an approach to be performed with great caution so as not to 1. : misinterpret an inflamed diverticula or covered perforation of it as well as not 2. : overlooking a peritoneal tumor lesion.


Subject(s)
Abdomen, Acute , Diverticulitis , Ovarian Cysts , Female , Humans , Adult , Abdomen, Acute/diagnosis , Abdomen, Acute/etiology , Abdomen, Acute/surgery , Diagnosis, Differential , Abdominal Pain/etiology , Diverticulitis/diagnosis , Hernia/complications , Hernia/diagnosis , Ovarian Cysts/complications , Ovarian Cysts/diagnosis
14.
Int J Gynaecol Obstet ; 161(3): 702-710, 2023 Jun.
Article in English | MEDLINE | ID: mdl-36373872

ABSTRACT

Surgical abnormalities of the adnexa in children and adolescents include a variety of ovarian and paraovarian lesions ranging from benign functional cysts to malignant tumors, torsion of the ovary and/or the fallopian tube, and adnexal infectious lesions ranging from salpingitis to tubo-ovarian abscesses. Presentations vary from asymptomatic pelvic masses to acute abdomen, and some ovarian tumors might present with precocious puberty or virilization. Acute pain might be caused by hemorrhage or rupture of ovarian or paraovarian cysts, adnexal torsion or adnexal infection. Differential diagnosis of adnexal masses should include peri-appendiceal abscess in all age groups, and endometriomas and ectopic pregnancy in adolescents. This review provides guidance on the differentiation between adnexal abnormalities, based on important clues from clinical assessment and diagnostic workup, and ultimately on the decision making about the need for surgery, its level of urgency, and the type of surgery to clinicians of all specialties involved in the care of young females.


Subject(s)
Adnexal Diseases , Cysts , Gynecology , Ovarian Cysts , Female , Child , Adolescent , Humans , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery , Adnexal Diseases/diagnosis , Adnexal Diseases/surgery , Adnexal Diseases/pathology , Torsion Abnormality/diagnosis , Torsion Abnormality/surgery
15.
J Pediatr Hematol Oncol ; 45(1): e126-e127, 2023 01 01.
Article in English | MEDLINE | ID: mdl-35398866

ABSTRACT

BACKGROUND: In newborns and infants, ovarian lesions can be detected during ultrasound examination before or after birth. Malignant ovarian lesions account for <1% of malignancies in newborns. However, in case of doubt about the nature of the lesion, surgery with tissue collection for histopathologic evaluation should be considered with the absolute condition of fertility preservation. OBSERVATIONS: The aim of this publication was to describe a case report of a 3-day-old infant who presented an ovarian lesion on postnatal ultrasound, with features suggesting a malignant nature of the ovary. In the described case, laparoscopy and mini-laparotomy were performed, torsion was excluded. The ovary was preserved, and histopathologic examination excluded the malignant nature of the lesion. CONCLUSION: A detailed analysis of the clinical status, laboratory tests, and imaging studies is necessary before making a final decision on further therapeutic, especially surgical management of a newborn with an ovarian lesion.


Subject(s)
Fertility Preservation , Laparoscopy , Ovarian Cysts , Ovarian Neoplasms , Infant , Female , Infant, Newborn , Humans , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery , Ovarian Neoplasms/pathology , Laparoscopy/methods , Retrospective Studies
16.
Tunis Med ; 101(10): 780-782, 2023 Oct 05.
Article in English | MEDLINE | ID: mdl-38465761

ABSTRACT

INTRODUCTION: Psoriasis is a common chronic inflammatory condition, often beginning in childhood in approximately one-third of cases. It can be associated with various other autoimmune diseases such as rheumatoid arthritis, celiac disease, and thyroid disorders. However, its co-occurrence with Van Wyk Grumbach syndrome has not been described in the pediatric population. This syndrome, resulting from untreated hypothyroidism, is characterized by early puberty and ovarian cysts. OBSERVATION: A 15-year-old adolescent with a diagnosis of psoriasis since the age of 9 presented with chronic constipation and headaches. She exhibited early puberty (menarche at 9 years) and academic regression. Clinical examination revealed growth retardation and arterial hypertension. Hormonal analyses revealed primary hypothyroidism : Free Thyroxine (FT4)=7pmol/mL(9- 20 pmol/l), Thyroid Stimulating Hormone (TSH)=200 mIU/mL( 0,4 - 5 mUI/ml.). The ultrasound and scintigraphic appearance were suggestive of thyroiditis. Additionally, she experienced menstrual irregularities and pelvic pain. Radiological exploration revealed a left ovarian cyst. The diagnosis of Van Wyk Grumbach syndrome was established due to early puberty, hypothyroidism, and polycystic ovary. Treatment with l-thyroxine led to stabilization of blood pressure and hormonal levels. Her height remained below the target adult height. CONCLUSION: Assessment of thyroid function appears necessary in pediatric patients with psoriasis. Early hormonal replacement therapy for hypothyroidism may alleviate the symptoms of Van Wyk Grumbach syndrome and mitigate its impact on stature.


Subject(s)
Hypothyroidism , Ovarian Cysts , Humans , Child , Female , Adolescent , Hypothyroidism/complications , Hypothyroidism/diagnosis , Hypothyroidism/drug therapy , Thyroxine/therapeutic use , Syndrome , Ovarian Cysts/complications , Ovarian Cysts/diagnosis , Ovarian Cysts/drug therapy
17.
JAAPA ; 35(12): 61-63, 2022 Dec 01.
Article in English | MEDLINE | ID: mdl-36412944

ABSTRACT

ABSTRACT: Benign mature cystic teratomas are a form of ovarian germ cell tumor that originates from primordial germ cells in the ovaries. Of the three types of teratoma neoplasms, benign mature cystic teratomas (also called dermoid cysts) are the most common. Patients may present with intermittent abdominal or pelvic pain, abdominal enlargement, dysmenorrhea, dyspareunia, or may be asymptomatic. Clinicians should have a high suspicion for benign mature cystic teratomas, which account for more than 20% of all ovarian neoplasms. This article focuses on the clinical symptoms, ovarian growth characteristics, pathophysiology, potential complications, management options, and recurrence of benign mature cystic teratomas.


Subject(s)
Ovarian Cysts , Ovarian Neoplasms , Teratoma , Female , Humans , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery , Teratoma/diagnosis , Teratoma/surgery , Teratoma/pathology , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/surgery
18.
Medicine (Baltimore) ; 101(43): e31643, 2022 Oct 28.
Article in English | MEDLINE | ID: mdl-36316838

ABSTRACT

RATIONALE: Anti-glomerular basement membrane (anti-GBM) disease during gestation is sparse and even rarer when combined with bilateral large corpus luteum cysts. In this case, we report a case of anti-GBM disease in the early stage of pregnancy with ruptured newly formed bilateral large corpus luteum cysts. PATIENT CONCERNS: A 24-year-old female was initially diagnosed with anti-GBM disease. During treatment, abdominal distention and vaginal bleeding successively staged. The results of the first gynecological ultrasound and abdominal CT were negative. DIAGNOSIS: Based on the dynamic imaging change of the ovaries, the elevated human chorionic gonadotropin (hCG) and sex hormones, and the pathological findings, a diagnosis of anti-GBM disease with rupture of the newly formed bilateral corpus luteum cysts during early pregnancy was considered. INTERVENTIONS: The patient was treated with corticosteroids, plasma-exchange along with intensive hemodialysis. Then, to confirm the diagnosis, laparoscopic debulking of bilateral ovarian cysts and curettage were performed. OUTCOMES: After treatment, the anti-GBM antibody titer declined and the condition of the patient was still stable 2 months following discharge. LESSONS: As clinicians, we should be aware that even if the first imaging tests are negative, the relevant indicators should be reviewed dynamically based on the condition of the patients. Additionally, this case raised the question of whether anti-GBM disease was associated with pregnancy and giant corpus luteum cysts, which needs further investigations.


Subject(s)
Anti-Glomerular Basement Membrane Disease , Ovarian Cysts , Pregnancy , Female , Humans , Young Adult , Adult , Anti-Glomerular Basement Membrane Disease/complications , Corpus Luteum , Ovarian Cysts/complications , Ovarian Cysts/diagnosis , Ovarian Cysts/surgery , Rupture/complications
19.
Jpn J Radiol ; 40(12): 1213-1234, 2022 Dec.
Article in English | MEDLINE | ID: mdl-35916971

ABSTRACT

There are many types of ovarian tumors, and these different types often form cystic masses with a similar appearance, which can make their differentiation difficult. However, with the exclusion of rare ovarian tumors, the number of ovarian tumors encountered in daily practice is somewhat fixed. It goes without saying that magnetic resonance imaging (MRI) is useful for differentiating ovarian tumors. In this review, we summarize the differential diagnoses for each of the five types of MRI findings commonly encountered in daily practice. First, unilocular cystic masses without mural nodules/solid components include benign lesions such as serous cystadenoma, functional cysts, surface epithelial inclusion cysts, paratubal cysts, and endometriosis. Second, multilocular cystic ovarian lesions include mucinous tumors and ovarian metastases. It should be noted that mucinous tumors may be diagnosed as borderline or carcinoma, even if no solid component is observed. Third, cystic lesions with mural nodules that are unrelated to endometriosis include serous borderline tumor and serous carcinoma. Cystic lesions with solid components are more likely to be malignant, but some may be diagnosed as benign. Fourth, ovarian tumors deriving from endometriosis include seromucinous borderline tumors, endometrioid carcinoma, and clear cell carcinoma. These tumors sometimes need to be differentiated from serous tumors. Finally, cystic lesions with lipid contents include teratoma-related tumors. In mature cystic teratoma, mural nodules (called "Rokitansky protuberance" or "dermoid nipple") are sometimes seen, but they do not suggest malignancy. Some of these lesions can be diagnosed accurately by considering their characteristic imaging findings, their changes over time, MRI findings other than those of the primary lesion, and information from other modalities such as tumor markers. To ensure the optimal treatment for ovarian tumors, it is important to estimate the histological type as well as to diagnose whether a lesion is benign or malignant.


Subject(s)
Carcinoma , Endometriosis , Neoplasms, Glandular and Epithelial , Ovarian Cysts , Ovarian Neoplasms , Teratoma , Female , Humans , Ovarian Neoplasms/diagnostic imaging , Ovarian Neoplasms/pathology , Ovarian Cysts/diagnosis , Ovarian Cysts/pathology , Diagnosis, Differential , Endometriosis/diagnostic imaging , Magnetic Resonance Imaging
20.
Andes Pediatr ; 93(2): 253-258, 2022 Apr.
Article in Spanish | MEDLINE | ID: mdl-35735305

ABSTRACT

INTRODUCTION: Bilateral complex ovarian cysts in newborns are rare and their reporting becomes imperative to in crease knowledge about the best therapeutic management. OBJECTIVE: To describe the clinical case of a newborn with a diagnosis of bilateral complex ovarian cysts and to discuss the conditions for conservative or surgical management according to the ultrasound characteristics of the cyst. CLINICAL CASE: At 35 weeks of gestational age, prenatal ultrasound identified the presence of cystic masses in both adnexa, so it was decided to interrupt the pregnancy by cesarean section at 37 weeks. After birth, bilateral ovarian cysts of 3.5 x 4.4 x 2.7 and 3.4 x 2.4 x 3.3 cm, right and left, respectively, were corro borated. The right cyst had a septum of 1.4 mm thick and thickened wall of 3 mm which was com patible with complex cysts. On the 4th day of extrauterine life, laparoscopic vacuum aspiration and deroofing with electrocautery of the upper wall of both cysts was performed, without complications. The diagnosis of ovarian serous cystadenoma was made by pathological anatomy. CONCLUSIONS: We describe a case with adequate prenatal diagnosis and laparoscopic surgical intervention of a bilateral ovarian cyst > 4 cm. Prenatal diagnosis is essential for choosing the best therapy management (con servative or surgical) depending on the echography characteristics of the cyst. Neonatal surgery is recommended for simple ovarian cysts >4 cm, complex cysts regardless of their size, and those that become complex cysts during conservative management.


Subject(s)
Cystadenoma , Ovarian Cysts , Ovarian Neoplasms , Cesarean Section , Cystadenoma/diagnosis , Cystadenoma/surgery , Female , Humans , Infant , Infant, Newborn , Ovarian Cysts/diagnosis , Ovarian Cysts/pathology , Ovarian Cysts/surgery , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/surgery , Pregnancy , Ultrasonography, Prenatal
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